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Y

Yuji Kashiwakura

jichi medical university
H指数:27
被引数:2,771

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Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation

构建一种紧凑型高保真金黄色葡萄球菌Cas9变体，并阐明其扩展靶向范围及活化的机制

Nature Communications
IF15.7
2026-04-160
OAAI
Satoshi N. Omura; Ryoya Nakagawa; Shohei Kajimoto; Sae Okazaki; Soh Ishiguro; Hideto Mori; Kosuke Onishi; Yuji Kashiwakura; Takafumi Hiramoto; Kio Horinaka; Mamoru Tanaka; Hisato Hirano; Kasey Jividen; Keitaro Yamashita; Shengdar Q. Tsai; Nozomu Yachie; Tsukasa Ohmori; Hiroshi Nishimasu; Osamu Nureki
Therapeutic base editing to generate a gain-of-function F9 variant for hemophilia B

通过治疗性碱基编辑生成具有获得性功能的F9变体以治疗血友病B

Blood
IF23.1
2025-10-280
OAAI
Nemekhbayar Baatartsogt; Yuji Kashiwakura; Takafumi Hiramoto; Rina Ito; Rikako Sato; Yasumitsu Nagao; Hina Naruoka; Haruka Takata; Morisada Hayakawa; Khishigjargal Batjargal; Tomoki Togashi; Atsushi Hoshino; Taro Shimizu; Yusuke Sato; Tatsuhiro Ishida; Osamu Nureki; Tsukasa Ohmori
The factor (F)VIII K1693N mutation (FVIII-Nara) in a patient with moderate hemophilia A confers resistance to thrombin-catalyzed cleavage at Arg1689 involving P4ʹ position

中等型血友病A患者中的因子（F）Ⅷ K1693N突变（FVIII-Nara）导致其对凝血酶催化的Arg1689裂解（涉及P4'位点）产生抵抗

Journal of Thrombosis and Haemostasis
IF5
2025-05-130
PRE
Shoko Furukawa; Nemekhbayar Baatartsogt; Takeshi Kawamura; Kaoru Horiuchi; Masaaki Doi; Yuji Kashiwakura; Tsukasa Ohmori; Keiji Nogami

研究方向

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T
Tsukasa Ohmori
H 指数:32论文数:173被引数:4,385
Y
Yoichi Sakata
H 指数:48论文数:300被引数:9,167
S
Seiji Madoiwa
H 指数:29论文数:127被引数:3,744
J
Jun Mimuro
H 指数:33论文数:197被引数:4,183
A
Akira Ishiwata
H 指数:16论文数:42被引数:931
N
Nemekhbayar Baatartsogt
H 指数:6论文数:29被引数:138
H
Hiromi Kumon
H 指数:54论文数:673被引数:9,708
Y
Yasutomo Nasu
H 指数:46论文数:576被引数:7,506
M
Masami Watanabe
H 指数:46论文数:513被引数:8,373
M
Morisada Hayakawa
H 指数:22论文数:61被引数:1,892