未登录 Cilia-independent gas-liquid transport, athird mechanism mediating airway mucus clearance 非纤毛依赖的气-液传输:调节气道黏液清除的第三种机制 Shenoy, Siddharth K.; Gutay, Mark; Brown, Ian; Rogers, Troy D.; Banner, Kane; Olegario, Nico; Griffin, Nicholas; Goodell, Henry P.; Yoder, Bryan; Lalush, David S.; Edwards, David A.; Boucher, Richard C.; Grubb, Barbara R.; Button, Brian 分享 收藏
BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance BPIFB1丢失改变气道粘液特性并减少粘液纤毛清除 Donoghue, Lauren J.; Markovetz, Matthew R.; Morrison, Cameron B.; Chen, Gang; McFadden, Kathryn M.; Sadritabrizi, Taraneh; Gutay, Mark I.; Kato, Takafumi; Rogers, Troy D.; Snead, Jazmin Y.; Livraghi-Butrico, Alessandra; Button, Brian; Ehre, Camille; Grubb, Barbara R.; Hill, David B.; Kelada, Samir N. P. 分享 收藏
Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration Mikami, Yu; Grubb, Barbara R.; Rogers, Troy D.; Dang, Hong; Asakura, Takanori; Kota, Pradeep; Gilmore, Rodney C.; Okuda, Kenichi; Morton, Lisa C.; Sun, Ling; Chen, Gang; Wykoff, Jason A.; Ehre, Camille; Vilar, Juan; van Heusden, Catharina; Livraghi-Butrico, Alessandra; Gentzsch, Martina; Button, Brian; Stutts, M. Jackson; Randell, Scott H.; O'Neal, Wanda K.; Boucher, Richard C. 分享 收藏
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Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection 全基因组双向CRISPR筛选将粘蛋白鉴定为调节SARS-CoV-2感染的宿主因子 Biering, Scott B.; Sarnik, Sylvia A.; Wang, Eleanor; Zengel, James R.; Leist, Sarah R.; Schafer, Alexandra; Sathyan, Varun; Hawkins, Padraig; Okuda, Kenichi; Tau, Cyrus; Jangid, Aditya R.; Duffy, Connor, V; Wei, Jin; Gilmore, Rodney C.; Alfajaro, Mia Madel; Strine, Madison S.; Nguyenla, Xammy; Van Dis, Erik; Catamura, Carmelle; Yamashiro, Livia H.; Belk, Julia A.; Begeman, Adam; Stark, Jessica C.; Shon, D. Judy; Fox, Douglas M.; Ezzatpour, Shahrzad; Huang, Emily; Olegario, Nico; Rustagi, Arjun; Volmer, Allison S.; Livraghi-Butrico, Alessandra; Wehri, Eddie; Behringer, Richard R.; Cheon, Dong-Joo; Schaletzky, Julia; Aguilar, Hector C.; Puschnik, Andreas S.; Button, Brian; Pinsky, Benjamin A.; Blish, Catherine A.; Baric, Ralph S.; O'Neal, Wanda K.; Bertozzi, Carolyn R.; Wilen, Craig B.; Boucher, Richard C.; Carette, Jan E.; Stanley, Sarah A.; Harris, Eva; Konermann, Silvana; Hsu, Patrick D. 分享 收藏
Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis Kato, Takafumi; Radicioni, Giorgia; Papanikolas, Micah J.; Stoychev, Georgi, V; Markovetz, Matthew R.; Aoki, Kazuhiro; Porterfield, Melody; Okuda, Kenichi; Cardenas, Selene M. Barbosa; Gilmore, Rodney C.; Morrison, Cameron B.; Ehre, Camille; Burns, Kimberlie A.; White, Kristen K.; Brennan, Tara A.; Goodell, Henry P.; Thacker, Holly; Loznev, Henry T.; Forsberg, Lawrence J.; Nagase, Takahide; Rubinstein, Michael; Randell, Scott H.; Tiemeyer, Michael; Hill, David B.; Kesimer, Mehmet; O'Neal, Wanda K.; Ballard, Stephen T.; Freeman, Ronit; Button, Brian; Boucher, Richard C. 分享 收藏
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A mucoadhesive biodissolvable thin film for localized and rapid delivery of lidocaine for the treatment of vestibulodynia 用于局部和快速递送利多卡因以治疗前庭痛的粘膜粘附性生物可溶性薄膜 Dahl, Denali K.; Whitesell, Ashlyn N.; Sharma-Huynh, Preetika; Maturavongsadit, Panita; Janusziewicz, Rima; Fox, Ryan J.; Loznev, Henry T.; Button, Brian; Schorzman, Allison N.; Zamboni, William; Ban, Jisun; Montgomery, Stephanie A.; Carey, Erin T.; Benhabbour, S. Rahima 分享 收藏
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Inhibition of ATP hydrolysis restores airway surface liquid production in cystic fibrosis airway epithelia van Heusden, Catharina; Button, Brian; Anderson, Wayne H.; Ceppe, Agathe; Morton, Lisa C.; O'Neal, Wanda K.; Dang, Hong; Alexis, Neil E.; Donaldson, Scott; Stephan, Holger; Boucher, Richard C.; Lazarowski, Eduardo R. 分享 收藏
IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis IL-1β 在囊性纤维化的前粘蛋白分泌细胞因子谱中占主导地位 Chen, Gang; Sun, Ling; Kato, Takafumi; Okuda, Kenichi; Martino, Mary B.; Abzhanova, Aiman; Lin, Jennifer M.; Gilmore, Rodney C.; Batson, Bethany D.; O'Neal, Yvonne K.; Volmer, Allison S.; Dang, Hong; Deng, Yangmei; Randell, Scott H.; Button, Brian; Livraghi-Butrico, Alessandra; Kesimer, Mehmet; Ribeiro, Carla M. P.; O'Neal, Wanda K.; Boucher, Richard C. 分享 收藏
Airways mucus pathogenesis in patients with non-cystic fibrosis bronchiectasis Ramsey, Kathryn; Radicioni, Giorgia; Hill, David; Ehre, Camille; Button, Brian; Alexis, Neil E.; Knowles, Michael; Donaldson, Scott; Kesimer, Mehmet; Mcguckin, Michael; Boucher, Richard 分享 收藏
Roles of mucus adhesion and cohesion in cough clearance Button, Brian; Goodell, Henry P.; Atieh, Eyad; Chen, Yu-Cheng; Williams, Robert; Shenoy, Siddharth; Lackey, Elijah; Shenkute, Nathan T.; Cai, Li-Heng; Dennis, Robert G.; Boucher, Richard C.; Rubinstein, Michael 分享 收藏
Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH 囊性纤维化患者的病理性粘液和粘液清除受损是由于浓度增加而不是pH改变所致 Hill, David B.; Long, Robert F.; Kissner, William J.; Atieh, Eyad; Garbarine, Ian C.; Markovetz, Matthew R.; Fontana, Nicholas C.; Christy, Matthew; Habibpour, Mehdi; Tarran, Robert; Forest, M. Gregory; Boucher, Richard C.; Button, Brian 分享 收藏
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Airway surface liquid pH is not acidic in children with cystic fibrosis Schultz, Andre; Puvvadi, Ramaa; Borisov, Sergey M.; Shaw, Nicole C.; Klimant, Ingo; Berry, Luke J.; Montgomery, Samuel T.; Nguyen, Thien; Kreda, Silvia M.; Kicic, Anthony; Noble, Peter B.; Button, Brian; Stick, Stephen M. 分享 收藏
Sialic acid-to-urea ratio as a measure of airway surface hydration Esther, Charles R., Jr.; Hill, David B.; Button, Brian; Shi, Shuai; Jania, Corey; Duncan, Elizabeth A.; Doerschuk, Claire M.; Chen, Gang; Ranganathan, Sarath; Stick, Stephen M.; Boucher, Richard C. 分享 收藏