未登录 Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification 全基因组测序揭示了冠状动脉钙化的两个基因座，并将ARSE鉴定为血管钙化的调节剂 de Vries, Paul S.; Conomos, Matthew P.; Singh, Kuldeep; Nicholson, Christopher J.; Jain, Deepti; Hasbani, Natalie R.; Jiang, Wanlin; Lee, Sujin; Lino Cardenas, Christian L.; Lutz, Sharon M.; Wong, Doris; Guo, Xiuqing; Yao, Jie; Young, Erica P.; Tcheandjieu, Catherine; Hilliard, Austin T.; Bis, Joshua C.; Bielak, Lawrence F.; Brown, Michael R.; Musharoff, Shaila; Clarke, Shoa L.; Terry, James G.; Palmer, Nicholette D.; Yanek, Lisa R.; Xu, Huichun; Heard-Costa, Nancy; Wessel, Jennifer; Selvaraj, Margaret Sunitha; Li, Rebecca H.; Sun, Xiao; Turner, Adam W.; Stilp, Adrienne M.; Khan, Alyna; Newman, Anne B.; Rasheed, Asif; Freedman, Barry I.; Kral, Brian G.; McHugh, Caitlin P.; Hodonsky, Chani; Saleheen, Danish; Herrington, David M.; Jacobs, David R., Jr.; Nickerson, Deborah A.; Boerwinkle, Eric; Wang, Fei Fei; Heiss, Gerardo; Jun, Goo; Kinney, Greg L.; Sigurslid, Haakon H.; Doddapaneni, Harshavardhan; Hall, Ira M.; Bensenor, Isabela M.; Broome, Jai; Crapo, James D.; Wilson, James G.; Smith, Jennifer A.; Blangero, John; Vargas, Jose D.; Mosquera, Jose Verdezoto; Smith, Joshua D.; Viaud-Martinez, Karine A.; Ryan, Kathleen A.; Young, Kendra A.; Taylor, Kent D.; Lange, Leslie A.; Emery, Leslie S.; Bittencourt, Marcio S.; Budoff, Matthew J.; Montasser, May E.; Yu, Miao; Mahaney, Michael C.; Mahamdeh, Mohammed S.; Fornage, Myriam; Franceschini, Nora; Lotufo, Paulo A.; Natarajan, Pradeep; Wong, Quenna; Mathias, Rasika A.; Gibbs, Richard A.; Do, Ron; Mehran, Roxana; Tracy, Russell P.; Kim, Ryan W.; Nelson, Sarah C.; Damrauer, Scott M.; Kardia, Sharon L. R.; Rich, Stephen S.; Fuster, Valentin; Napolioni, Valerio; Zhao, Wei; Tian, Wenjie; Yin, Xianyong; Min, Yuan-, I; Manning, Alisa K.; Peloso, Gina; Kelly, Tanika N.; O'Donnell, Christopher J.; Morrison, Alanna C.; Curran, Joanne E.; Zapol, Warren M.; Bowden, Donald W.; Becker, Lewis C.; Correa, Adolfo; Mitchell, Braxton D.; Psaty, Bruce M.; Carr, John Jeffrey; Pereira, Alexandre C.; Assimes, Themistocles L.; Stitziel, Nathan O.; Hokanson, John E.; Laurie, Cecelia A.; Rotter, Jerome I.; Vasan, Ramachandran S.; Post, Wendy S.; Peyser, Patricia A.; Miller, Clint L.; Malhotra, Rajeev 分享 收藏
分享 收藏
Electronic cigarette vaping with aged coils causes acute lung injury in mice Goto, Shunsaku; Grange, Robert M. H.; Pinciroli, Riccardo; Rosales, Ivy A.; Li, Rebecca; Boerboom, Sophie L.; Ostrom, Katrina F.; Marutani, Eizo; Wanderley, Hatus, V; Bagchi, Aranya; Colvin, Robert B.; Berra, Lorenzo; Minaeva, Olga; Goldstein, Lee E.; Malhotra, Rajeev; Zapol, Warren M.; Ichinose, Fumito; Yu, Binglan 分享 收藏
High-Throughput Assay to Screen Small Molecules for Their Ability to Prevent Sickling of Red Blood Cells Nakagawa, Akito; Cooper, Marissa K.; Kost-Alimova, Maria; Berstler, James; Yu, Binglan; Berra, Lorenzo; Klings, Elizabeth S.; Huang, Mary S.; Heeney, Matthew M.; Bloch, Donald B.; Zapol, Warren M. 分享 收藏
The Antarctic Weddell seal genome reveals evidence of selection on cardiovascular phenotype and lipid handling Noh, Hyun Ji; Turner-Maier, Jason; Schulberg, S. Anne; Fitzgerald, Michael L.; Johnson, Jeremy; Allen, Kaitlin N.; Huckstadt, Luis A.; Batten, Annabelle J.; Alfoldi, Jessica; Costa, Daniel P.; Karlsson, Elinor K.; Zapol, Warren M.; Buys, Emmanuel S.; Lindblad-Toh, Kerstin; Hindle, Allyson G. 分享 收藏
Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction Malhotra, Rajeev; Nicholson, Christopher J.; Wang, Dongyu; Bhambhani, Vijeta; Paniagua, Samantha; Slocum, Charles; Sigurslid, Haakon H.; Cardenas, Christian L. Lino; Li, Rebecca; Boerboom, Sophie L.; Chen, Yin-Ching; Hwang, Shih-Jen; Yao, Chen; Ichinose, Fumito; Bloch, Donald B.; Lindsay, Mark E.; Lewis, Gregory D.; Aragam, Jayashri R.; Hoffmann, Udo; Mitchell, Gary F.; Hamburg, Naomi M.; Vasan, Ramchandran S.; Benjamin, Emelia J.; Larson, Martin G.; Zapol, Warren M.; Cheng, Susan; Roh, Jason D.; O'Donnell, Christopher J.; Nguyen, Christopher; Levy, Daniel; Ho, Jennifer E. 分享 收藏
Inhaled high dose nitric oxide is a safe and effective respiratory treatment in spontaneous breathing hospitalized patients with COVID-19 pneumonia 在新型冠状病毒肺炎肺炎的自主呼吸住院患者中，吸入大剂量一氧化氮是一种安全有效的呼吸治疗方法。 Fakhr, Bijan Safaee; Di Fenza, Raffaele; Gianni, Stefano; Wiegand, Steffen B.; Miyazaki, Yusuke; Morais, Caio C. Araujo; Gibson, Lauren E.; Chang, Marvin G.; Mueller, Ariel L.; Rodriguez-Lopez, Josanna M.; Ackman, Jeanne B.; Arora, Pankaj; Scott, Louie K.; Bloch, Donald B.; Zapol, Warren M.; Carroll, Ryan W.; Ichinose, Fumito; Berra, Lorenzo 分享 收藏
UBA6 and NDFIP1 regulate the degradation of ferroportin Traeger, Lisa; Wiegand, Steffen B.; Sauer, Andrew J.; Corman, Benjamin H. P.; Peneyra, Kathryn M.; Wunderer, Florian; Fischbach, Anna; Bagchi, Aranya; Malhotra, Rajeev; Zapol, Warren M.; Bloch, Donald B. 分享 收藏
Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome Grange, Robert M. H.; Sharma, Rohit; Shah, Hardik; Reinstadler, Bryn; Goldberger, Olga; Cooper, Marissa K.; Nakagawa, Akito; Miyazaki, Yusuke; Hindle, Allyson G.; Batten, Annabelle J.; Wojtkiewicz, Gregory R.; Schleifer, Grigorij; Bagchi, Aranya; Marutani, Eizo; Malhotra, Rajeev; Bloch, Donald B.; Ichinose, Fumito; Mootha, Vamsi K.; Zapol, Warren M. 分享 收藏
分享 收藏
High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19) Fakhr, Bijan Safaee; Wiegand, Steffen B.; Pinciroli, Riccardo; Gianni, Stefano; Morais, Caio C. A.; Ikeda, Takamitsu; Miyazaki, Yusuke; Marutani, Eizo; Di Fenza, Raffaele; Larson, Grant M.; Parcha, Vibhu; Gibson, Lauren E.; Chang, Marvin G.; Arora, Pankaj; Carroll, Ryan W.; Kacmarek, Robert M.; Ichinose, Fumito; Barth, William H.; Kaimal, Anjali; Hohmann, Elizabeth L.; Zapol, Warren M.; Berra, Lorenzo 分享 收藏
分享 收藏
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance 靶向循环乳酸以减轻细胞内NADH:NAD失衡的工程酶 Patgiri, Anupam; Skinner, Owen S.; Miyazaki, Yusuke; Schleifer, Grigorij; Marutani, Eizo; Shah, Hardik; Sharma, Rohit; Goodman, Russell P.; To, Tsz-Leung; Bao, Xiaoyan Robert; Ichinose, Fumito; Zapol, Warren M.; Mootha, Vamsi K. 分享 收藏
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype Malhotra, Rajeev; Mauer, Andreas C.; Cardenas, Christian L. Lino; Guo, Xiuqing; Yao, Jie; Zhang, Xiaoling; Wunderer, Florian; Smith, Albert, V; Wong, Quenna; Pechlivanis, Sonali; Hwang, Shih-Jen; Wang, Judy; Lu, Lingyi; Nicholson, Christopher J.; Shelton, Georgia; Buswell, Mary D.; Barnes, Hanna J.; Sigurslid, Haakon H.; Slocum, Charles; O'Rourke, Caitlin; Rhee, David K.; Bagchi, Aranya; Nigwekar, Sagar U.; Buys, Emmanuel S.; Campbell, Catherine Y.; Harris, Tamara; Budoff, Matthew; Criqui, Michael H.; Rotter, Jerome, I; Johnson, Andrew D.; Song, Ci; Franceschini, Nora; Debette, Stephanie; Hoffmann, Udo; Kaelsch, Hagen; Noethen, Markus M.; Sigurdsson, Sigurdur; Freedman, Barry, I; Bowden, Donald W.; Jckel, Karl-Heinz; Moebus, Susanne; Erbel, Raimund; Feitosa, Mary F.; Gudnason, Vilmundur; Thanassoulis, George; Zapol, Warren M.; Lindsay, Mark E.; Bloch, Donald B.; Post, Wendy S.; O'Donnell, Christopher J. 分享 收藏
分享 收藏
Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation Jain, Isha H.; Zazzeron, Luca; Goldberger, Olga; Marutani, Eizo; Wojtkiewicz, Gregory R.; Ast, Tslil; Wang, Hong; Schleifer, Grigorij; Stepanova, Anna; Brepoels, Kathleen; Schoonjans, Luc; Carmeliet, Peter; Galkin, Alexander; Ichinose, Fumito; Zapol, Warren M.; Mootha, Vamsi K. 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome Schleifer, Grigorij; Marutani, Eizo; Ferrari, Michele; Sharma, Rohit; Skinner, Owen; Goldberger, Olga; Grange, Robert Matthew Henry; Peneyra, Kathryn; Malhotra, Rajeev; Wepler, Martin; Ichinose, Fumito; Bloch, Donald B.; Mootha, Vamsi K.; Zapol, Warren M. 分享 收藏
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
未登录.png){kind=icon}