Steven K. Albanese - Publications, H-index & Citations

Steven K. Albanese

schrodinger inc.

14H指数

39论文数

1.2K被引数

收录论文 14

发表时间

Discovery of 2H-Pyrrolo[3; 4-c]pyridin-3-one Derivatives as Type-III c-MET Inhibitors Enabled by Free-Energy Perturbation Calculations 通过自由能微扰计算发现2H-吡咯并[3;4-c]吡啶-3-酮衍生物作为III型c-MET抑制剂

ACS Medicinal Chemistry Letters

IF4

2026-05-08

PREAI

Eric Therrien; Shulu Feng; Katherine Amberg-Johnson; Nadim Shaikh; Pradeep Patil; Sarmistha Majumdar; Nikita Abraham; Daniel Eiler; Steffen Kutter; Steven K. Albanese; Susanta Haldar; Kyle G. Kroeck; Christian Atsriku; Aleksey I. Gerasyuto; Adam M. Levinson

Structure-Based Discovery of Imidazo[4; 5-c]pyridine SARM1 Modulators Showing Paradoxical Activation 基于结构的咪唑并[4;5-c]吡啶SARM1调节剂的发现及其显示出的矛盾性激活

Journal of Medicinal Chemistry

IF6.8

2026-04-08

PREAI

Steven K. Albanese; Brittany E. Hopkins; Andrea M. Olland; Alexis Fairman; Nadim Shaikh; Shulu Feng; Mahesh Thakkar; Andreas Verras; Alexey Dementiev; Ward G. Walkup 4th; Christian Atsriku; Harathi D. Srinivas; Wayne Allen; Khuram Ashraf; Pieter H. Bos; Peng Hsiao; Kyle Kroeck; Zhijian Liu; Anu Nagarajan; Christopher T. Szlenk; Mats Svensson; Zachary Lee Johnson; Kanishk Kapilashrami; Stephen Rubino; Andrew Kaplan; Adam M. Levinson

Predicting Resistance to Small Molecule Kinase Inhibitors

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2025-02-20

PREAI

Nagarajan, Anu; Amberg-Johnson, Katherine; Paull, Evan; Huang, Kunling; Ghanakota, Phani; Chandrasinghe, Asela; Elk, Jackson Chief; Sampson, Jared M.; Wang, Lingle; Abel, Robert; Albanese, Steven K.

The maximal and current accuracy of rigorous protein-ligand binding free energy calculations 严格的蛋白质-配体结合自由能计算的最大和当前准确性

COMMUNICATIONS CHEMISTRY

IF6.2

2023-10-14

OAAI

Ross, Gregory A.; Lu, Chao; Scarabelli, Guido; Albanese, Steven K.; Houang, Evelyne; Abel, Robert; Harder, Edward D.; Wang, Lingle

Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance Abl激酶的突变与药物结合动力学的改变表明伊马替尼耐药的新机制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-11-16

PREAI

Lyczek, Agatha; Berger, Benedict-Tilman; Rangwala, Aziz M.; Paung, YiTing; Tom, Jessica; Philipose, Hannah; Guo, Jiaye; Albanese, Steven K.; Robers, Matthew B.; Knapp, Stefan; Chodera, John D.; Seeliger, Markus A.

Structural basis for isoform-specific inhibition of human CTPS1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-09-28

OAAI

Lynch, Eric M.; DiMattia, Michael A.; Albanese, Steven; van Zundert, Gydo C. P.; Hansen, Jesse M.; Quispe, Joel D.; Kennedy, Madison A.; Verras, Andreas; Borrelli, Kenneth; Toms, Angela, V; Kaila, Neelu; Kreutter, Kevin D.; McElwee, Joshua J.; Kollman, Justin M.

Is Structure-Based Drug Design Ready for Selectivity Optimization?

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2020-10-29

OAAI

Albanese, Steven K.; Chodera, John D.; Volkamer, Andrea; Keng, Simon; Abel, Robert; Wang, Lingle

A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization

CELL REPORTS

IF6.9

2019-10-01

OAAI

Wojnarowicz, Paulina M.; Lima e Silva, Raquel; Ohnaka, Masayuki; Lee, Sang Bae; Chin, Yvette; Kulukian, Anita; Chang, Sung-Hee; Desai, Bina; Escolano, Marta Garcia; Shah, Riddhi; Garcia-Cao, Marta; Xu, Sijia; Kadam, Rashmi; Goldgur, Yehuda; Miller, Meredith A.; Ouerfelli, Ouathek; Yang, Guangli; Arakawa, Tsutomu; Albanese, Steven K.; Garland, William A.; Stoller, Glenn; Chaudhary, Jaideep; Norton, Larry; Soni, Rajesh Kumar; Philip, John; Hendrickson, Ronald C.; Iavarone, Antonio; Dannenberg, Andrew J.; Chodera, John D.; Pavletich, Nikola; Lasorella, Anna; Campochiaro, Peter A.; Benezra, Robert

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

NATURE COMMUNICATIONS

IF15.7

2019-06-19

102

OAAI

Minuesa, Gerard; Albanese, Steven K.; Xie, Wei; Kazansky, Yaniv; Worroll, Daniel; Chow, Arthur; Schurer, Alexandra; Park, Sun-Mi; Rotsides, Christina Z.; Taggart, James; Rizzi, Andrea; Naden, Levi N.; Chou, Timothy; Gourkanti, Saroj; Cappel, Daniel; Passarelli, Maria C.; Fairchild, Lauren; Adura, Carolina; Glickman, J. Fraser; Schulman, Jessica; Famulare, Christopher; Patel, Minal; Eibl, Joseph K.; Ross, Gregory M.; Bhattacharya, Shibani; Tan, Derek S.; Leslie, Christina S.; Beuming, Thijs; Patel, Dinshaw J.; Goldgur, Yehuda; Chodera, John D.; Kharas, Michael G.

Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations

COMMUNICATIONS BIOLOGY

IF5.1

2018-06-13

OAAI

Hauser, Kevin; Negron, Christopher; Albanese, Steven K.; Ray, Soumya; Steinbrecher, Thomas; Abel, Robert; Chodera, John D.; Wang, Lingle

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

ELIFE

IF0

2018-02-21

OAAI

Ruff, Emily F.; Muretta, Joseph M.; Thompson, Andrew R.; Lake, Eric W.; Cyphers, Soreen; Albanese, Steven K.; Hanson, Sonya M.; Behr, Julie M.; Thomas, David D.; Chodera, John D.; Levinson, Nicholas M.

A small molecule pan Id protein antagonist shows strong antitumor activity

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Wojnarowicz, Paulina M.; Desai, Bina; Chin, Yvette; Lee, Sang Bae; Garcia-Cao, Marta; Ouerfelli, Ouathek; Yang, Guangli; Xu, Sijia; Goldgur, Yehuda; Miller, Meredith A.; Chaudhary, Jaideep; Garland, William A.; Albanese, Steven K.; Soni, Rajesh; Philip, John; Norton, Larry; Rosen, Neal; Hendrickson, Ronald C.; Zhou, Xi Kathy; Iavarone, Antonio; Dannenberg, Andrew J.; Chodera, John D.; Pavletich, Nikola; Lasorella, Anna; Benezra, Robert

Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2016-08-02

OAAI

Xu, Jianing; Pham, Can G.; Albanese, Steven K.; Dong, Yiyu; Oyama, Toshinao; Lee, Chung-Han; Rodrik-Outmezguine, Vanessa; Yao, Zhan; Han, Song; Chen, David; Parton, Daniel L.; Chodera, John D.; Rosen, Neal; Cheng, Emily H.; Hsieh, James J.

Simulating mTOR Hyperactivating Mutations to Understand Functionally Significant Structural Rearrangements

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Albanese, Steven; Xu, Jianing; Hsieh, James; Chodera, John D.

研究方向