Anders Tengholm - Publications, H-index & Citations

Anders Tengholm

Uppsala University

42H指数

141论文数

5.2K被引数

收录论文 65

发表时间

The Welander TIA1 mutation dedifferentiates insulin-producing cells — reversal by a GLP-1 receptor agonist Welander TIA1基因突变使胰岛素分泌细胞去分化——GLP-1受体激动剂可逆转此过程

Journal of Biological Chemistry

IF3.9

2026-03-03

OAAI

Tongjian Zhao; Jing Cen; Xuan Wang; Mingyu Yang; Joey Lau; Anders Tengholm; Åke Sjöholm; Nils Welsh

Real-time detection of somatostatin release from single islets reveals hypersecretion in type 2 diabetes 实时检测单个胰岛中生长抑素释放揭示了2型糖尿病中的高分泌现象

ACTA PHYSIOLOGICA

IF0

2025-01-13

OAAI

Yang, MY; Mandal, K; Södergren, M; Dumral, Ö; Winroth, L; Tengholm, A

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

DIABETOLOGIA

IF10.2

2024-05-14

OAAI

Ibrahim, Hazem; Balboa, Diego; Saarimaeki-Vire, Jonna; Montaser, Hossam; Dyachok, Oleg; Lund, Per-Eric; Omar-Hmeadi, Muhmmad; Kvist, Jouni; Dwivedi, Om P.; Lithovius, Vaino; Barsby, Tom; Chandra, Vikash; Eurola, Solja; Ustinov, Jarkko; Tuomi, Tiinamaija; Miettinen, Paivi J.; Barg, Sebastian; Tengholm, Anders; Otonkoski, Timo

Bo Hellman, 19 June 1930-4 December 2023

DIABETOLOGIA

IF10.2

2024-04-25

OAAI

Gylfe, Erik; Tengholm, Anders

OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion

CELL REPORTS

IF6.9

2024-04-01

OAAI

Panagiotou, Styliani; Tan, Kia Wee; Nguyen, Phuoc My; Mueller, Andreas; Oqua, Affiong Ika; Tomas, Alejandra; Wendt, Anna; Eliasson, Lena; Tengholm, Anders; Solimena, Michele; Idevall-Hagren, Olof

Indicator-dependent differences in detection of local intracellular Ca2+release events evoked by voltage-gated Ca2+entry in pancreatic β-cells

CELLULAR SIGNALLING

IF3.7

2023-09-01

OAAI

Yang, Mingyu; Dyachok, Oleg; Xu, Yunjian; Gylfe, Erik; Idevall-Hagren, Olof; Tengholm, Anders

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells

NATURE BIOTECHNOLOGY

IF41.7

2022-03-03

169

OAAI

Balboa, Diego; Barsby, Tom; Lithovius, Vaino; Saarimaki-Vire, Jonna; Omar-Hmeadi, Muhmmad; Dyachok, Oleg; Montaser, Hossam; Lund, Per-Eric; Yang, Mingyu; Ibrahim, Hazem; Naatanen, Anna; Chandra, Vikash; Vihinen, Helena; Jokitalo, Eija; Kvist, Jouni; Ustinov, Jarkko; Nieminen, Anni I.; Kuuluvainen, Emilia; Hietakangas, Ville; Katajisto, Pekka; Lau, Joey; Carlsson, Per-Ola; Barg, Sebastian; Tengholm, Anders; Otonkoski, Timo

Mitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion

MOLECULAR METABOLISM

IF6.6

2021-09-01

OAAI

Vishnu, N.; Hamilton, A.; Bagge, A.; Wernersson, A.; Cowan, E.; Barnard, H.; Sancak, Y.; Kamer, K. J.; Spegel, P.; Fex, M.; Tengholm, A.; Mootha, V. K.; Nicholls, D. G.; Mulder, H.

Glucose-induced cAMP elevation in β-cells involves amplification of constitutive and glucagon-activated GLP-1 receptor signalling 葡萄糖诱导的 β 细胞cAMP升高涉及组成型和胰高血糖素激活的GLP-1受体信号传导的放大

ACTA PHYSIOLOGICA

IF5.6

2021-01-09

OAAI

Shuai, Hongyan; Xu, Yunjian; Ahooghalandari, Parvin; Tengholm, Anders

Metabolic regulation of calcium signaling in beta cells Β 细胞中钙信号的代谢调节

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2020-07-01

OAAI

Idevall-Hagren, Olof; Tengholm, Anders

Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes

NATURE COMMUNICATIONS

IF15.7

2020-04-20

OAAI

Omar-Hmeadi, Muhmmad; Lund, Per-Eric; Gandasi, Nikhil R.; Tengholm, Anders; Barg, Sebastian

?-Hydroxybutyrate does not mediate glucose inhibition of glucagon secretion ？-羟基丁酸不介导胰高血糖素分泌的葡萄糖抑制

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-04-01

OAAI

Yu, Qian; Lai, Bao Khanh; Ahooghalandari, Parvin; Helander, Anders; Gylfe, Erik; Gilon, Patrick; Tengholm, Anders

In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-01-21

OAAI

Petrenko, Volodymyr; Gandasi, Nikhil R.; Sage, Daniel; Tengholm, Anders; Barg, Sebastian; Dibner, Charna

Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

CELLS

IF5.2

2019-12-15

OAAI

Pietila, Ilkka; Van Mourik, Djenolan; Tamelander, Andreas; Kriz, Viterslav; Claesson-Welsh, Lena; Tengholm, Anders; Welsh, Michael

A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells

CELLS

IF5.2

2019-12-06

OAAI

Xu, Yunjian; Schwede, Frank; Wienk, Hans; Tengholm, Anders; Rehmann, Holger

Cyclic AMP links glucose stimulation to somatostatin secretion in δ-cells

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2019-08-14

OAAI

Tengholm, Anders

Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis

ELIFE

IF0

2019-05-20

OAAI

Gucek, Alenka; Gandasi, Nikhil R.; Omar-Hmeadi, Muhmmad; Bakke, Marit; Doskeland, Stein O.; Tengholm, Anders; Barg, Sebastian

Glucose controls glucagon secretion by directly modulating cAMP in alpha cells 葡萄糖通过直接调节 α 细胞中的cAMP来控制胰高血糖素的分泌

DIABETOLOGIA

IF10.2

2019-04-05

OAAI

Yu, Qian; Shuai, Hongyan; Ahooghalandari, Parvin; Gylfe, Erik; Tengholm, Anders

Fusion Pore Regulation by EPAC2/cAMP Controls Cargo Release during Insulin Exocytosis

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Gucek, Alenka; Gandasi, Nikhil R.; Omar-Hmeadi, Muhmmad; Bakke, Marit; Doskeland, Stein; Tengholm, Anders; Barg, Sebastian

Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling

DIABETES

IF7.5

2019-01-22

OAAI

Ghiasi, Seyed Mojtaba; Dahlby, Tina; Andersen, Caroline Hede; Haataja, Leena; Petersen, Solrun; Omar-Hmeadi, Muhmmad; Yang, Mingyu; Pihl, Celina; Bresson, Sophie Emilie; Khilji, Muhammad Saad; Klindt, Kristian; Cheta, Oana; Perone, Marcelo J.; Tyrberg, Bjorn; Prats, Clara; Barg, Sebastian; Tengholm, Anders; Arvan, Peter; Mandrup-Poulsen, Thomas; Marzec, Michal Tomasz

研究方向