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Phase 1/2 AAV5-hRKp.RPGR RPGR (Botaretigene Sparoparvovec) Gene Therapy: Safety and Efficacy in RPGR-Associated X-Linked Retinitis Pigmentosa Michaelides, Michel; Besirli, Cagri G.; Yang, Yesa; De Guimaraes, Thales A. C.; Wong, Sui Chien; Huckfeldt, Rachel M.; Comander, Jason I.; Sahel, Jose-Alain; Shah, Syed Mahmood; Tee, James J. L.; Kumaran, Neruban; Georgiadis, Anastasios; Minnick, Pansy; Zeldin, Robert; Naylor, Stuart; Xu, Jialin; Clark, Michael; Anglade, Eddy; Wong, Peggy; Fleck, Penny R.; Fung, Albert; Peluso, Colleen; Kalitzeos, Angelos; Georgiou, Michalis; Ripamonti, Caterina; Smith, Alexander J.; Ali, Robin R.; Forbes, Alexandria; Bainbridge, James 分享 收藏
QM107, a novel CD148 (RTP Type J) activating peptide therapy for treating neovascular age-related macular degeneration Arokiasamy, Samantha; Balderstone, Michaela J. M.; Shaik, Faheem; Cristante, Enrico; Moseley, Thomas C.; Madoo, Akshay; Rizzi, Matteo; Bainbridge, James W.; Tsoyi, Konstantin; Rosas, Ivan O.; Whiteford, James R.; De Rossi, Giulia 分享 收藏
Restoration of vision after transplantation of photoreceptors (vol 485, pg 99, 2012) 视力的恢复：光感受器移植后（vol 485, pg 99, 2012） Pearson, R. A.; Barber, A. C.; Rizzi, M.; Hippert, C.; Xue, T.; West, E. L.; Duran, Y.; Smith, A. J.; Chuang, J. Z.; Azam, S. A.; Luhmann, U. F. O.; Benucci, A.; Sung, C. H.; Bainbridge, J. W.; Carandini, M.; Yau, K. -W.; Sowden, J. C.; Ali, R. R. 分享 收藏
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Effective AAV-mediated gene replacement therapy in retinal organoids modeling AIPL1-associated LCA4 Sai, Hali; Ollington, Bethany; Rezek, Farah O.; Chai, Niuzheng; Lane, Amelia; Georgiadis, Tassos; Bainbridge, James; Michaelides, Michel; Sacristan-Reviriego, Almudena; Perdigao, Pedro R. L.; Leung, Amy; van der Spuy, Jacqueline 分享 收藏
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First-in-Human Gene Therapy Trial of AAV8-hCARp.h CNGB3 in Adults and Children With CNGB3-associated Achromatopsia Michaelides, Michel; Hirji, Nashila; Wong, Sui Chien; Besirli, Cagri G.; Zaman, Serena; Kumaran, Neruban; Georgiadis, Anastasios; Smith, Alexander J.; Ripamonti, Caterina; Gottlob, Irene; Robson, Anthony G.; Thiadens, Alberta; Henderson, Robert H.; Fleck, Penny; Anglade, Eddy; Dong, Xiangwen; Capuano, George; Lu, Wentao; Berry, Pamela; Kane, Thomas; Naylor, Stuart; Georgiou, Michalis; Kalitzeos, Angelos; Ali, Robin R.; Forbes, Alexandria; Bainbridge, James 分享 收藏
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Investigation of PTC124-mediated translational readthrough in a retinal organoid model of AIPL1-associated Leber congenital amaurosis Leung, Amy; Sacristan-Reviriego, Almudena; Perdigao, Pedro R. L.; Sai, Hali; Georgiou, Michalis; Kalitzeos, Angelos; Carr, Amanda -Jayne F.; Coffey, Peter J.; Michaelides, Michel; Bainbridge, James; Cheetham, Michael E.; Spuy, Jacqueline van der 分享 收藏
Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis Zihni, Ceniz; Georgiadis, Anastasios; Ramsden, Conor M.; Sanchez-Heras, Elena; Haas, Alexis J.; Nommiste, Britta; Semenyuk, Olha; Bainbridge, James W. B.; Coffey, Peter J.; Smith, Alexander J.; Ali, Robin R.; Balda, Maria S.; Matter, Karl 分享 收藏
Antioxidant and lipid supplementation improve the development of photoreceptor outer segments in pluripotent stem cell-derived retinal organoids West, Emma L.; Majumder, Paromita; Naeem, Arifa; Fernando, Milan; O'Hara-Wright, Michelle; Lanning, Emily; Kloc, Magdalena; Ribeiro, Joana; Ovando-Roche, Patrick; Shum, Ian O.; Jumbu, Neeraj; Sampson, Robert; Hayes, Matt; Bainbridge, James W. B.; Georgiadis, Anastasios; Smith, Alexander J.; Gonzalez-Cordero, Anai; Ali, Robin R. 分享 收藏
Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization Klaska, Izabela P.; White, Anne; Villacampa, Pilar; Hoke, Justin; Abelleira-Hervas, Laura; Maswood, Ryea N.; Ali, Robin R.; Bunce, Catey; Unwin, Richard D.; Cooper, Garth J. S.; Bishop, Paul N.; Bainbridge, James W. 分享 收藏
RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Muller glial cell hypertrophy in progressive retinal degeneration RNAi介导的波形蛋白或胶质纤维酸性蛋白的抑制可防止进行性视网膜变性中Muller胶质细胞肥大的建立 Hippert, Claire; Graca, Anna B.; Basche, Mark; Kalargyrou, Aikaterini A.; Georgiadis, Anastasios; Ribeiro, Joana; Matsuyama, Ayako; Aghaizu, Nozie; Bainbridge, James W.; Smith, Alexander J.; Ali, Robin R.; Pearson, Rachael A. 分享 收藏
Pathological Angiogenesis Requires Syndecan-4 for Efficient VEGFA-Induced VE-Cadherin Internalization De Rossi, Giulia; Vahatupa, Maria; Cristante, Enrico; Arokiasamy, Samantha; Liyanage, Sidath E.; May, Ulrike; Pellinen, Laura; Uusitalo-Jarvinen, Hannele; Bainbridge, James W.; Jarvinen, Tero A. H.; Whiteford, James R. 分享 收藏
Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors Ribeiro, Joana; Procyk, Christopher A.; West, Emma L.; O'Hara-Wright, Michelle; Martins, Monica F.; Khorasani, Majid Moshtagh; Hare, Aura; Basche, Mark; Fernando, Milan; Goh, Debbie; Jumbo, Neeraj; Rizzi, Matteo; Powell, Kate; Tariq, Menahil; Michaelides, Michel; Bainbridge, James W. B.; Smith, Alexander J.; Pearson, Rachael A.; Gonzalez-Cordero, Anai; Ali, Robin R. 分享 收藏
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Contemporary Outcomes and Prognostic Factors of 23-Gauge Vitrectomy for Retained Lens Fragments After Phacoemulsification Chan, Errol W.; Yang, Elizabeth; Eldeeb, Mohab; Bainbridge, James W.; Cruz, Lyndon; Sullivan, Paul S.; Muqit, Mahi M.; Charteris, David G.; Minihan, Miriam; Ezra, Eric; Wickham, Louisa 分享 收藏
Clinical and functional analyses of AIPL1 variants reveal mechanisms of pathogenicity linked to different forms of retinal degeneration Sacristan-Reviriego, Almudena; Le, Hoang Mai; Georgiou, Michalis; Meunier, Isabelle; Bocquet, Beatrice; Roux, Anne-Francoise; Prodromou, Chrisostomos; Bainbridge, James; Michaelides, Michel; van der Spuy, Jacqueline 分享 收藏
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