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陈耕 封面图

陈耕 (Geng Chen)

The Chinese University of Hong Kong, Shenzhen

43H指数
275论文数
9.3K被引数
收录论文 91
发表时间
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Structures of G-protein coupled receptor HCAR3 in complex with selective agonists reveal the basis for ligand recognition and selectivityG蛋白偶联受体HCAR3与选择性激动剂复合物的结构揭示了配体识别和选择性的基础
errPLOS BIOLOGY
IF7.2
err2025-12-08
err0
PREAI
errYe, Fang; Zhang, Zhiyi; Zhang, Binghao; Li, Xinyu; Deng, Jiaxi; Miao, Qian; Ning, Peiruo; Chi, Yunlin; Chen, Geng; Wu, Zhangsong; Wang, Qian; Xu, Lezhi; Gong, Ningjie; Cheng, Bangning; Ma, Zhigang; Qian, Chungen; Zhu, Lizhe; Pan, Xin; Du, Yang
err分享
err收藏
Ultrasonic-Stoichiometric Dual Regulation of Antisite Defects for Enhanced Electromagnetic Wave Absorption
errADVANCED FUNCTIONAL MATERIALS
IF19
err2025-12-01
err0
PREAI
errChen, Geng; Hui, Shengchong; Zhang, Limin; Deng, Lechun; Shen, Hao; Li, Xuexiang; Li, Xiangcheng; Chen, Qiang; Wu, Hongjing
err分享
err收藏
Study on the Effects and Mechanism of Action of Tungsten/Calcium Fluoride System on the Combustion Characteristics of Delay Composition钨/氟化钙体系对延期药燃烧特性的效应及作用机理研究
errPropellants Explosives Pyrotechnics
IF2
err2025-11-01
err0
PREAI
errHao, Bo; Dong, Zhitao; Cui, Yuxiang; Chen, Geng; Lu, Yuangen
err分享
err收藏
Calreticulin Enhances Therapeutic Immune Responses of Dry Thermostat-Stressed Hepatocellular Carcinoma Cell Vaccine钙网蛋白增强干恒温器应激的肝细胞癌细胞的疫苗治疗性免疫反应
errACS Nano
IF16
err2025-10-13
err0
PREAI
errDa Zhang; Xinyue Fu; Chenxi Zhou; Xiaohua Xing; Youshi Zheng; Yang Zhou; Xiaoyuan Zheng; Geng Chen; Jianhua Zou; Yongyi Zeng; Xiaolong Liu
err分享
err收藏
Combustion Rate Regulation and Combustion Characteristics Analysis of Near-Zero Oxygen Balance Tungsten Delay Compositions Based on 1-μm Tungsten Powder for One-Second Delay Time基于1-μm钨粉、用于一秒延迟时间的近零氧平衡钨延迟组分的燃烧速率调控与燃烧特性分析
errCOMBUSTION SCIENCE AND TECHNOLOGY
IF1.5
err2025-10-01
err0
PREAI
errLu, Yuan-Gen; Hao, Bo; Dong, Zhi-Tao; Chen, Geng; Zhang, Li
err分享
err收藏
Ginsenoside Accumulation and Enzyme Functional Characterization of Zingibroside R1 and Ginsenoside Ro Biosynthesis in Panax zingiberensis人参皂苷积累及zingibroside R1和人参皂苷Ro生物合成中酶的功能表征在Panax zingiberensis中
errPlant Physiology and Biochemistry
IF5.7
err2025-10-01
err0
PREAI
errYunfei Hu; Chenshuo Zhang; Geng Chen; Guanghui Zhang; Ming Zhao; Shengchao Yang; Junrong Tang; Qingyan Tang
err分享
err收藏
Mechanism and function of GPR3 regulated by a negative allosteric modulatorGPR3受负变构调节剂的调节机制与功能
errNature Communications
IF15.7
err2025-08-27
err0
errOAAI
errGeng Chen; Jana Bláhová; Nico Staffen; Harald Hübner; Nadja Nunhöfer; Chen Qiu; Peter Gmeiner; Dorothee Weikert; Yang Du; Jun Xu
err分享
err收藏
Dual-Locking the SARS-CoV-2 Spike Trimer: An Amphipathic Molecular Bolt Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition双重锁定SARS-CoV-2刺突三聚体：一种两亲性分子锁扣稳定保守的可成药界面以抑制冠状病毒
errADVANCED SCIENCE
IF14.1
err2025-04-26
err0
errOAAI
errLi, SL; Ye, F; Zheng, YC; Wang, J; Peng, HR; Zhu, LL; Chen, LL; Yu, T; Ge, H; He, JQ; Zhang, BH; Wu, JY; Zhang, ZY; Jiang, LL; Chen, G; Zhao, P; Lan, K; Zhao, ZJ; Qian, XH; Xu, K; Du, Y; Li, HL
err分享
err收藏
Structures of G-protein coupled receptor HCAR1 in complex with Gi1 protein reveal the mechanistic basis for ligand recognition and agonist selectivityG蛋白偶联受体HCAR1与Gi1蛋白复合物的结构揭示了配体识别和激动剂选择性的机制基础
errPLOS BIOLOGY
IF7.2
err2025-04-15
err0
errOAAI
errPan, Xin; Ye, Fang; Ning, Peiruo; Yu, Yiping; Zhang, Zhiyi; Wang, Jingxuan; Chen, Geng; Wu, Zhangsong; Qiu, Chen; Li, Jiancheng; Chen, Bangning; Zhu, Lizhe; Qian, Chungen; Du, Yang
err分享
err收藏
USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance
errSCIENTIFIC REPORTS
IF3.9
err2025-03-14
err0
errOAAI
errZhou, Bo; Li, Jie; Wu, Shuai; Zhang, Haomiao; Luo, Yuanbo; Chen, Jingxiang; Chen, Geng
err分享
err收藏
Telomere-to-telomere genome assembly and 3D chromatin architecture of Centella asiatica insight into evolution and genetic basis of triterpenoid saponin biosynthesis端粒到端粒基因组组装和3D染色质结构揭示积雪草在三萜皂苷生物合成中的进化和遗传基础
errHORTICULTURE RESEARCH
IF8.5
err2025-02-07
err0
errOAAI
errSong, Wan-ling; Chen, Bao-zheng; Feng, Lei; Chen, Geng; He, Si-mei; Hao, Bing; Zhang, Guang-hui; Dong, Yang; Yang, Sheng-chao
err分享
err收藏
Targeting Mesothelin Enhances Personalized Neoantigen Vaccine Induced Antitumor Immune Response in Orthotopic Pancreatic Cancer Mouse Models靶向Mesothelin增强个性化新抗原疫苗诱导的正位胰腺癌小鼠模型中的抗肿瘤免疫应答
errADVANCED SCIENCE
IF14.1
err2025-01-31
err0
errOAAI
errCai, ZX; Li, ZL; Zhong, WT; Lin, FZ; Dong, XQ; Ye, HH; Guo, YT; Chen, G; Yu, XL; Yu, HJ; Tang, RJ; Liu, XL
err分享
err收藏
Investigation of human aging at the single-cell level单细胞水平的人类衰老研究
errAGEING RESEARCH REVIEWS
IF12.4
err2024-11-01
err0
PREAI
errLi, Yunjin; Wang, Qixia; Xuan, Yuan; Zhao, Jian; Li, Jin; Tian, Yuncai; Chen, Geng; Tan, Fei
err分享
err收藏
Structural basis for ligand recognition of the human hydroxycarboxylic acid receptor HCAR3
errCELL REPORTS
IF6.9
err2024-11-01
err0
errOAAI
errYe, Fang; Pan, Xin; Zhang, Zhiyi; Xiang, Xufu; Li, Xinyu; Zhang, Binghao; Ning, Peiruo; Liu, Aijun; Wang, Qinggong; Gong, Kaizheng; Li, Jiancheng; Zhu, Lizhe; Qian, Chungen; Chen, Geng; Du, Yang
err分享
err收藏
Structural basis for the ligand recognition and G protein subtype selectivity of kisspeptin receptor
errSCIENCE ADVANCES
IF12.5
err2024-08-16
err0
errOAAI
errWu, Zhangsong; Chen, Geng; Qiu, Chen; Yan, Xiaoyi; Xu, Lezhi; Jiang, Shirui; Xu, Jun; Han, Runyuan; Shi, Tingyi; Liu, Yiming; Gao, Wei; Wang, Qian; Li, Jiancheng; Ye, Fang; Pan, Xin; Zhang, Zhiyi; Ning, Peiruo; Zhang, Binghao; Chen, Jing; Du, Yang
err分享
err收藏
Editorial: Comprehensive profiling cancer immunity with multimodal approaches for clinical management
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-04-30
err0
errOAAI
errChen, Geng; Shi, Yi; Xiao, Wenming; Kreil, David P.
err分享
err收藏
Structural and functional characterization of the endogenous agonist for orphan receptor GPR3
errCELL RESEARCH
IF25.9
err2024-01-30
err4
errOAAI
errChen, Geng; Staffen, Nico; Wu, Zhangsong; Xu, Xinyu; Pan, Jinheng; Inoue, Asuka; Shi, Tingyi; Gmeiner, Peter; Du, Yang; Xu, Jun
err分享
err收藏
Integrated omics landscape of hepatocellular carcinoma suggests proteomic subtypes for precision therapy
errCELL REPORTS MEDICINE
IF10.6
err2023-12-01
err14
errOAAI
errXing, Xiaohua; Hu, En; Ouyang, Jiahe; Zhong, Xianyu; Wang, Fei; Liu, Kaixin; Cai, Linsheng; Zhou, Yang; Wang, Yingchao; Chen, Geng; Li, Zhenli; Wu, Liming; Liu, Xiaolong
err分享
err收藏
Developments and challenges in neoadjuvant therapy for locally advanced pancreatic cancer
errWORLD JOURNAL OF GASTROENTEROLOGY
IF5.4
err2023-09-21
err3
errOAAI
errZhou, Bo; Zhang, Shi-Ran; Chen, Geng; Chen, Ping
err分享
err收藏
Clinical evaluation of radiation-induced sinusitis by MRI-based scoring system in nasopharyngeal carcinoma patients
errRADIATION ONCOLOGY
IF3.2
err2023-09-18
err2
errOAAI
errZheng, Wenya; Yan, Tao; Liu, Dongjiao; Chen, Geng; Wen, Yingjuan; Rao, Xiuli; Wang, Yizhe; Zheng, Huijuan; Yang, Jiahong; Peng, Hua
err分享
err收藏

研究方向

生物化学与分子生物学生物与医药结构生物学深圳市基础研究面上项目，2022年10月至2025年10月Chen QiuYiming LiuXiaoyi YanQiaohui LiShirui JiangJun XuXin PanFang YeZhiyi ZhangPeiruo NingBinghao ZhangLezhi XuBangning ChengXufu XiangChungen Qian*Yang Du*催乳素释放肽受体信号转导与G蛋白偶联选择性结构研究蛋白质组学泛素连接酶Geng Chen#*Chen Qiu#Runyuan HanTingyi ShiWei GaoQian WangJiancheng LiJing Chen*: eadn7771.structural basisligand recognitionG protein subtype selectivitykisspeptin receptorXinyu LiAijun LiuQinggong WangKaizheng GongLizhe ZhuGeng Chen*hydroxycarboxylic acid receptor HCAR3Nico StaffenZhangsong WuXinyu XuJinheng PanAsuka InouePeter GmeinerYang Du孤儿受体GPR3内源性配体结构与功能表征Geng Chen#Haoqing WangSheng CaoJie HengXavier DeupiGPCR结构测定Yezhou Liu#Wenping Lyu#Junlin WangQiwen LiaoG蛋白偶联受体结构生物学Qiwen Liao#Wenping LyuWei Gao#Guodong HeZicheng ZengThian‐Sze Wong#Shiyi GanXiankun WangYunjun GeHaizhan JiaoQiang ChenYezhou LiuGydo CP van ZundertMichael J RobertsonGeorgios SkiniotisHongli HuN-甲酰肽作为病原体相关分子模式的识别结构基础Maximilian F SchmidtChen BaiQiuyuan LuZheng LiuShuai Fang#Rakhee GantiTatiana A ChernovaLi ZhouDuc DuongHiroaki KiyokawaMing LiBo ZhaoNatalia ShcherbikYury O Chernoff内吞作用调控朊蛋白分子伴侣机制Ling MaHuihui LiuRichard D YeCryo-EM结构胆汁酸受体TGR5
合作学者
合作期刊
王
王军 (Jun Wang)
H 指数: 222 · 论文数: 3.2K
A
Arieh Warshel
H 指数: 123 · 论文数: 594
张
张丽 (Li Zhang)
H 指数: 121 · 论文数: 2.6K
J
John H. Zhang
H 指数: 115 · 论文数: 1.5K
G
Gordon K. Smyth
H 指数: 113 · 论文数: 595
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