Ronan M. T. Fleming - Publications, H-index & Citations

Ronan M. T. Fleming

ollscoil na gaillimhe-university of galway

44H指数

165论文数

1.4W被引数

收录论文 46

发表时间

KinForm: kinetics-informed feature optimised representation models for enzyme kcat and KM prediction KinForm：基于动力学信息特征优化的酶kcat和KM预测模型

npj Systems Biology and Applications

IF3.5

2026-03-28

OAAI

Saleh Alwer; Ronan M. T. Fleming

Constraint-based modelling of metabolic dysregulation in Gaucher disease: mitochondrial dysfunction and disrupted cholesterol homeostasis

Orphanet Journal of Rare Diseases

IF3.5

2026-01-20

OAAI

Yanjun Liu; Xi Luo; Samira Ranjbar; Johannes M. F. G. Aerts; Martijn van der Lienden; Andrea Dardis; Ronan M. T. Fleming

Characterisation of conserved and reacting moieties in chemical reaction networks 化学反应网络中保守和反应基团的表征

Journal of Theoretical Biology

IF2

2026-01-01

PREAI

Rahou, Hadjar; Haraldsdottir, Hulda S.; Martinelli, Filippo; Thiele, Ines; Fleming, Ronan M. T.

XomicsToModel: omics data integration and generation of thermodynamically consistent metabolic models XomicsToModel：组学数据整合和热力学一致代谢模型的生成

Nature Protocols

IF16

2025-12-01

PREAI

German Preciat; Agnieszka B. Wegrzyn; Xi Luo; Ines Thiele; Thomas Hankemeier; Ronan M. T. Fleming

GBA1 Gene-Associated Transcriptomic Signatures Reveal Risk Genes in Parkinson’s Disease GBA1基因相关的转录组特征揭示了帕金森病中的风险基因

Biomedicines 2025, Vol. 13, Page 2799

IF3.9

2025-11-18

OAAI

Yanjun Liu; Xi Luo; Ronan M. T. Fleming

mzQuality: An Open-Source Software Tool for Quality Monitoring and Reporting of Targeted Mass Spectrometry Measurements mzQuality：一个用于靶向质谱测量质量监控和报告的开源软件工具

Journal of the American Society for Mass Spectrometry

IF2.7

2025-07-25

OAAI

Marielle van der Peet; Pascal Maas; Agnieszka Wegrzyn; Lieke Lamont; Ronan Fleming; Constance Bordes; Stéphanie Debette; Amy Harms; Thomas Hankemeier; Alida Kindt

The role of dopaminergic medication and specific pathway alterations in idiopathic and PRKN/PINK1-mediated Parkinson's disease 多巴胺能药物的作用以及特发性与PRKN/PINK1介导的帕金森病中的特定通路改变

SCIENCE ADVANCES

IF12.5

2025-05-16

PREAI

Balck, Alexander; Borsche, Max; Campbell, Philip; Luo, Xi; Harvey, John; Brueckmann, Theresa; Ludwig, Charlotte; Harms, Amy; Lohmann, Katja; Brown, Emmeline; Morris, Huw R.; Schapira, Anthony H.; Hankemeier, Thomas; Fleming, Ronan; Szymczak, Silke

A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites 一个包含247,092种不同人类微生物的基因组规模代谢重建资源，跨越多个大陆、年龄组和身体部位。

CELL SYSTEMS

IF7.7

2025-02-01

OAAI

Heinken, Almut; Hulshof, Timothy Otto; Nap, Bram; Martinelli, Filippo; Basile, Arianna; O'Brolchain, Amy; O'Sullivan, Neil Francis; Gallagher, Celine; Magee, Eimer; Mcdonagh, Francesca; Lalor, Ian; Bergin, Maeve; Evans, Phoebe; Daly, Rachel; Farrell, Ronan; Delaney, Rose Mary; Hill, Saoirse; Mcauliffe, Saoirse Roisin; Kilgannon, Trevor; Fleming, Ronan M. T.; Thinnes, Cyrille C.; Thiele, Ines

Identification of metabolites reproducibly associated with Parkinson's Disease via meta-analysis and computational modelling

NPJ PARKINSONS DISEASE

IF8.2

2024-06-29

OAAI

Luo, Xi; Liu, Yanjun; Balck, Alexander; Klein, Christine; Fleming, Ronan M. T.

Omics data integration suggests a potential idiopathic Parkinson's disease signature

COMMUNICATIONS BIOLOGY

IF5.1

2023-11-20

OAAI

Zagare, Alise; Preciat, German; Nickels, Sarah. L.; Luo, Xi; Monzel, Anna S.; Gomez-Giro, Gemma; Robertson, Graham; Jaeger, Christian; Sharif, Jafar; Koseki, Haruhiko; Diederich, Nico J.; Glaab, Enrico; Fleming, Ronan M. T.; Schwamborn, Jens C.

Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine 用于个性化医疗的7,302人类微生物的基因组规模代谢重建

NATURE BIOTECHNOLOGY

IF41.7

2023-01-19

OAAI

Heinken, Almut; Hertel, Johannes; Acharya, Geeta; Ravcheev, Dmitry A. A.; Nyga, Malgorzata; Okpala, Onyedika Emmanuel; Hogan, Marcus; Magnusdottir, Stefania; Martinelli, Filippo; Nap, Bram; Preciat, German; Edirisinghe, Janaka N. N.; Henry, Christopher S. S.; Fleming, Ronan M. T.; Thiele, Ines

Phenotype-Agnostic Molecular Subtyping of Neurodegenerative Disorders: The Cincinnati Cohort Biomarker Program (CCBP)

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2020-10-08

OAAI

Sturchio, Andrea; Marsili, Luca; Vizcarra, Joaquin A.; Dwivedi, Alok K.; Kauffman, Marcelo A.; Duker, Andrew P.; Lu, Peixin; Pauciulo, Michael W.; Wissel, Benjamin D.; Hill, Emily J.; Stecher, Benjamin; Keeling, Elizabeth G.; Vagal, Achala S.; Wang, Lily; Haslam, David B.; Robson, Matthew J.; Tanner, Caroline M.; Hagey, Daniel W.; El Andaloussi, Samir; Ezzat, Kariem; Fleming, Ronan M. T.; Lu, Long J.; Little, Max A.; Espay, Alberto J.

Personalized whole-body models integrate metabolism, physiology, and the gut microbiome

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2020-05-28

125

OAAI

Thiele, Ines; Sahoo, Swagatika; Heinken, Almut; Hertel, Johannes; Heirendt, Laurent; Aurich, Maike K.; Fleming, Ronan M. T.

MEMOTE for standardized genome-scale metabolic model testing (vol 38, pg 272, 2020)标准化基因组规模代谢模型测试备忘录 (第38卷，272页，2020页)

NATURE BIOTECHNOLOGY

IF41.7

2020-03-19

OAAI

Lieven, Christian; Beber, Moritz E.; Olivier, Brett G.; Bergmann, Frank T.; Ataman, Meric; Babaei, Parizad; Bartell, Jennifer A.; Blank, Lars M.; Chauhan, Siddharth; Correia, Kevin; Diener, Christian; Draeger, Andreas; Ebert, Birgitta E.; Edirisinghe, Janaka N.; Faria, Jose P.; Feist, Adam M.; Fengos, Georgios; Fleming, Ronan M. T.; Garcia-Jimenez, Beatriz; Hatzimanikatis, Vassily; van Helvoirt, Wout; Henry, Christopher S.; Hermjakob, Henning; Herrgard, Markus J.; Kaafarani, Ali; Kim, Hyun Uk; King, Zachary; Klamt, Steffen; Klipp, Edda; Koehorst, Jasper J.; Koenig, Matthias; Lakshmanan, Meiyappan; Lee, Dong-Yup; Lee, Sang Yup; Lee, Sunjae; Lewis, Nathan E.; Liu, Filipe; Ma, Hongwu; Machado, Daniel; Mahadevan, Radhakrishnan; Maia, Paulo; Mardinoglu, Adil; Medlock, Gregory L.; Monk, Jonathan M.; Nielsen, Jens; Nielsen, Lars Keld; Nogales, Juan; Nookaew, Intawat; Palsson, Bernhard O.; Papin, Jason A.; Patil, Kiran R.; Poolman, Mark; Price, Nathan D.; Resendis-Antonio, Osbaldo; Richelle, Anne; Rocha, Isabel; Sanchez, Benjamin J.; Schaap, Peter J.; Sheriff, Rahuman S. Malik; Shoaie, Saeed; Sonnenschein, Nikolaus; Teusink, Bas; Vilaca, Paulo; Vik, Jon Olav; Wodke, Judith A. H.; Xavier, Joana C.; Yuan, Qianqian; Zakhartsev, Maksim; Zhang, Cheng

MEMOTE for standardized genome-scale metabolic model testing 标准化基因组规模代谢模型测试备忘录

NATURE BIOTECHNOLOGY

IF41.7

2020-03-02

283

OAAI

Lieven, Christian; Beber, Moritz E.; Olivier, Brett G.; Bergmann, Frank T.; Ataman, Meric; Babaei, Parizad; Bartell, Jennifer A.; Blank, Lars M.; Chauhan, Siddharth; Correia, Kevin; Diener, Christian; Draeger, Andreas; Ebert, Birgitta E.; Edirisinghe, Janaka N.; Faria, Jose P.; Feist, Adam M.; Fengos, Georgios; Fleming, Ronan M. T.; Garcia-Jimenez, Beatriz; Hatzimanikatis, Vassily; van Helvoirt, Wout; Henry, Christopher S.; Hermjakob, Henning; Herrgard, Markus J.; Kaafarani, Ali; Kim, Hyun Uk; King, Zachary; Klamt, Steffen; Klipp, Edda; Koehorst, Jasper J.; Koenig, Matthias; Lakshmanan, Meiyappan; Lee, Dong-Yup; Lee, Sang Yup; Lee, Sunjae; Lewis, Nathan E.; Liu, Filipe; Ma, Hongwu; Machado, Daniel; Mahadevan, Radhakrishnan; Maia, Paulo; Mardinoglu, Adil; Medlock, Gregory L.; Monk, Jonathan M.; Nielsen, Jens; Nielsen, Lars Keld; Nogales, Juan; Nookaew, Intawat; Palsson, Bernhard O.; Papin, Jason A.; Patil, Kiran R.; Poolman, Mark; Price, Nathan D.; Resendis-Antonio, Osbaldo; Richelle, Anne; Rocha, Isabel; Sanchez, Benjamin J.; Schaap, Peter J.; Malik Sheriff, Rahuman S.; Shoaie, Saeed; Sonnenschein, Nikolaus; Teusink, Bas; Vilaca, Paulo; Vik, Jon Olav; Wodke, Judith A. H.; Xavier, Joana C.; Yuan, Qianqian; Zakhartsev, Maksim; Zhang, Cheng

LC-MS/MS analysis of the central energy and carbon metabolites in biological samples following derivatization by dimethylaminophenacyl bromide

JOURNAL OF CHROMATOGRAPHY A

IF4

2019-12-01

OAAI

Willacey, Cornelius C. W.; Naaktgeboren, Martijn; Moreno, Edinson Lucumi; Wegrzyn, Agnieszka B.; van der Es, Daan; Karu, Naama; Fleming, Ronan M. T.; Harms, Amy C.; Hankemeier, Thomas

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson's Disease 微生物组和纵向代谢组数据的综合分析揭示了微生物-宿主相互作用对帕金森病硫代谢的影响

CELL REPORTS

IF6.9

2019-11-01

109

OAAI

Hertel, Johannes; Harms, Amy C.; Heinken, Almut; Baldini, Federico; Thinnes, Cyrille C.; Glaab, Enrico; Vasco, Daniel A.; Pietzner, Maik; Stewart, Isobel D.; Wareham, Nicholas J.; Langenberg, Claudia; Trenkwalder, Claudia; Krueger, Rejko; Hankemeier, Thomas; Fleming, Ronan M. T.; Mollenhauer, Brit; Thiele, Ines

Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease 肠道微生物中次级胆汁酸代谢的系统评估揭示了炎症性肠病中不同的代谢能力

MICROBIOME

IF12.7

2019-05-15

219

OAAI

Heinken, Almut; Raycheev, Dmitry A.; Baldini, Federico; Heirendt, Laurent; Fleming, Ronan M. T.; Thiele, Ines

Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0 使用COBRA Toolbox v.3.0创建和分析基于生化约束的模型

NATURE PROTOCOLS

IF16

2019-02-20

723

OAAI

Heirendt, Laurent; Arreckx, Sylvain; Pfau, Thomas; Mendoza, Sebastian N.; Richelle, Anne; Heinken, Almut; Haraldsdottir, Hulda S.; Wachowiak, Jacek; Keating, Sarah M.; Vlasov, Vanja; Magnusdottir, Stefania; Ng, Chiam Yu; Preciat, German; Zagare, Alise; Chan, Siu H. J.; Aurich, Maike K.; Clancy, Catherine M.; Modamio, Jennifer; Sauls, John T.; Noronha, Alberto; Bordbar, Aarash; Cousins, Benjamin; El Assal, Diana C.; Valcarcel, Luis V.; Apaolaza, Inigo; Ghaderi, Susan; Ahookhosh, Masoud; Ben Guebila, Marouen; Kostromins, Andrejs; Sompairac, Nicolas; Le, Hoai M.; Ma, Ding; Sun, Yuekai; Wang, Lin; Yurkovich, James T.; Oliveira, Miguel A. P.; Vuong, Phan T.; El Assal, Lemmer P.; Kuperstein, Inna; Zinovyev, Andrei; Hinton, H. Scott; Bryant, William A.; Aragon Artacho, Francisco J.; Planes, Francisco J.; Stalidzans, Egils; Maass, Alejandro; Vempala, Santosh; Hucka, Michael; Saunders, Michael A.; Maranas, Costas D.; Lewis, Nathan E.; Sauter, Thomas; Palsson, Bernhard O.; Thiele, Ines; Fleming, Ronan M. T.

Automated microfluidic cell culture of stem cell derived dopaminergic neurons

SCIENTIFIC REPORTS

IF3.9

2019-02-11

OAAI

Kane, Khalid I. W.; Moreno, Edinson Lucumi; Hachi, Siham; Walter, Moriz; Jarazo, Javier; Oliveira, Miguel A. P.; Hankemeier, Thomas; Vulto, Paul; Schwamborn, Jens C.; Thoma, Martin; Fleming, Ronan M. T.

研究方向