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B

Beat Bornhäuser

University Children's Hospital Zurich
H指数:38
被引数:1.1万

个人简介

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荣誉奖项

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ADVANCED DRUG RESPONSE PROFILING AND IMMUNOPHENOTYPING TO PRIORITIZE TREATMENT OPTIONS FOR PEDIATRIC MDS WITH EXCESS BLASTS
EJC Paediatric Oncology
IF0
2025-11-010
OAAI
Haladik, Ben; Maurer-Granofszky, Margarita; Hurt, Anna; Koelbl, Claudia M.; Scheidegger, Nastassja; Gutnik, Silvia; Steffen, Fabio; De Moerloose, Barbara; Hasle, Henrik; Ussowicz, Marek; Vinci, Luca; Noellke, Ayami Yoshimi; Bourquin, Jean-Pierre; Niemeyer, Charlotte; Schmugge, Markus; Bornhauser, Beat; Erlacher, Miriam; Dworzak, Michael N.; Boztug, Kaan
INTEGRATED IMMUNOPHENOTYPING AND DRUG RESPONSE PROFILING REVEALS SUBTYPE-SPECIFIC SUSCEPTIBILITIES IN PEDIATRIC MDS WITH EXCESS BLASTS
EJC Paediatric Oncology
IF0
2025-11-010
OA
Scheidegger-Egloff, Nastassja; Gutnik, Silvia; Moeller, Claudia; Steffen, Fabio; Arpagaus, Arianna; Schori, Larissa; Schuehle, Selina; Bohler, Sheila; Haladik, Ben; Hurt, Anna; Koebl, Claudia M.; Granofszky, Margarita Maurer; De Moerloose, Barbara; Hasle, Henrik; Niemeyer, Charlotte; Ussowicz, Marek; Vinci, Luca; Yoshimi-Noellke, Ayami; Boztug, Kaan; Dworzak, Michael N.; Bourquin, Jean-Pierre; Erlacher, Miriam; Schmugge, Markus; Bornhauser, Beat
Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12

NUP98::KDM5A融合癌蛋白通过转录和表观遗传重编程直接激活CDK12

Nature Communications
IF15.7
2025-05-190
OAAI
Selina Troester; Thomas Eder; Nadja Wukowits; Martin Piontek; Pablo Fernández-Pernas; Johannes Schmoellerl; Ben Haladik; Gabriele Manhart; Melanie Allram; Margarita Maurer-Granofszky; Nastassja Scheidegger; Karin Nebral; Giulio Superti-Furga; Roland Meisel; Beat Bornhauser; Peter Valent; Michael N. Dworzak; Johannes Zuber; Kaan Boztug; Florian Grebien
SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response

SOD2是蛋白酶体降解的调控因子，促进适应性细胞饥饿反应。

CELL REPORTS
IF6.9
2025-04-010
PRE
Ibrahim, Nurul Khalida; Schreek, Sabine; Cinar, Buesra; Stasche, Anna Sophie; Lee, Su Hyun; Zeug, Andre; Dolgner, Tim; Niessen, Julia; Ponimaskin, Evgeni; Shcherbata, Halyna; Fehlhaber, Beate; Bourquin, Jean-Pierre; Bornhauser, Beat; Stanulla, Martin; Pich, Andreas; Gutierrez, Alejandro; Hinze, Laura
Caspase-2 kills cells with extra centrosomes
SCIENCE ADVANCES
IF12.5
2024-11-010
OAAI
Rizzotto, Dario; Vigorito, Vincenza; Rieder, Patricia; Gallob, Filip; Moretta, Gian Mario; Soratroi, Claudia; Riley, Joel S.; Bellutti, Florian; Veli, Stefano Li; Mattivi, Alessia; Lohmuller, Michael; Herzog, Sebastian; Bornhauser, Beat C.; Jacotot, Etienne D.; Villunger, Andreas; Fava, Luca L.
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers
HAEMATOLOGICA
IF7.9
2024-06-201
OAAI
Spriano, Filippo; Sartori, Giulio; Sgrignani, Jacopo; Barnabei, Laura; Arribas, Alberto J.; Guala, Matilde; Del Amor, Ana Maria Carrasco; Tomasso, Meagan R.; Tarantelli, Chiara; Cascione, Luciano; Golino, Gaetanina; Riveiro, Maria E.; Bortolozzi, Roberta; Lupia, Antonio; Paduano, Francesco; Huguet, Samuel; Rezai, Keyvan; Rinaldi, Andrea; Margheriti, Francesco; Ventura, Pedro; Guarda, Greta; Costa, Giosue; Rocca, Roberta; Furlan, Alberto; Verdonk, Luuk M.; Innocenti, Paolo; Martin, Nathaniel I.; Viola, Giampietro; Driessen, Christoph; Zucca, Emanuele; Stathis, Anastasios; Gahtory, Digvijay; van den Nieuwboer, Maurits; Bornhauser, Beat; Alcaro, Stefano; Trapasso, Francesco; Cristobal, Susana; Padrick, Shae B.; Pazzi, Natalina; Cavalli, Franco; Cavalli, Andrea; Gaudio, Eugenio; Bertoni, Francesco
Proteogenomic profiling uncovers differential therapeutic vulnerabilities between TCF3::PBX1 and TCF3::HLF translocated B-cell acute lymphoblastic leukemia
HAEMATOLOGICA
IF7.9
2024-02-290
OAAI
Bluemel, Lena; Bernardi, Flavia; Picard, Daniel; Diaz, Jacob Torrejon; Jepsen, Vera H.; Hasselmann, Rebecca; Schliehe-Diecks, Julian; Bartl, Jasmin; Qin, Nan; Bornhauser, Beat; Bhatia, Sanil; Marovka, Blerim; Marsaud, Veronique; Dingli, Florent; Loew, Damarys; Stanulla, Martin; Bourqin, Jean-Pierre; Borkhardt, Arndt; Remke, Marc; Ayrault, Olivier; Fischer, Ute
CD127 is expressed by acute lymphoblastic leukemias and is efficiently targeted by the IL7R-antagonist OSE-127 through macrophage-mediated antibody dependent phagocytosis
CANCER RESEARCH
IF16.6
2023-04-041
PRE
Baccelli, Irene; Lenk, Lennart; Laqua, Anna; Winterberg, Dorothee; Dietterle, Anna; Corallo, Frederique; Taurelle, Julien; Narbeburu, Emma; Bornhauser, Beat; Bourquin, Jean-Pierre; Vogiatzi, Fotini; Raffel, Simon; Schrappe, Martin; Cario, Gunnar; Brueggemann, Monika; Schewe, Denis M.; Poirier, Nicolas
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia
SCIENCE ADVANCES
IF12.5
2022-12-096
OAAI
Jin, Qi; Diaz, Blanca Gutierrez; Pieters, Tim; Zhou, Yalu; Narang, Sonali; Fijalkwoski, Igor; Borin, Cristina; Van Laere, Jolien; Payton, Monique; Cho, Byoung-Kyu; Han, Cuijuan; Sun, Limin; Serafin, Valentina; Yacu, George; Von Loocke, Wouter; Basso, Giuseppe; Veltri, Giulia; Dreveny, Ingrid; Ben-Sahra, Issam; Ah Goo, Young; Safgren, Stephanie L.; Tsai, Yi-Chien; Bornhauser, Beat; Suraneni, Praveen Kumar; Gaspar-Maia, Alexandre; Kandela, Irawati; Van Vlierberghe, Pieter; Crispino, John D.; Tsirigos, Aristotelis; Ntziachristos, Panagiotis
Functional analysis of structural variants in single cells using Strand-seq

使用strne-seq对单细胞中的结构变体进行功能分析

NATURE BIOTECHNOLOGY
IF41.7
2022-11-2416
OAAI
Jeong, Hyobin; Grimes, Karen; Rauwolf, Kerstin K.; Bruch, Peter-Martin; Rausch, Tobias; Hasenfeld, Patrick; Benito, Eva; Roider, Tobias; Sabarinathan, Radhakrishnan; Porubsky, David; Herbst, Sophie A.; Erarslan-Uysal, Busra; Jann, Johann-Christoph; Marschall, Tobias; Nowak, Daniel; Bourquin, Jean-Pierre; Kulozik, Andreas E.; Dietrich, Sascha; Bornhauser, Beat; Sanders, Ashley D.; Korbel, Jan O.
Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis
BLOOD ADVANCES
IF7.1
2022-08-227
OAAI
Vogiatzi, Fotini; Heymann, Julia; Muller, Kristina; Winterberg, Dorothee; Drakul, Aneta; Rosner, Thies; Lenk, Lennart; Heib, Michelle; Gehlert, Carina Lynn; Cario, Gunnar; Schrappe, Martin; Claviez, Alexander; Bornhauser, Beat; Bourquin, Jean-Pierre; Bomken, Simon; Adam, Dieter; Frielitz, Fabian-Simon; Maecker-Kolhoff, Britta; Stanulla, Martin; Valerius, Thomas; Peipp, Matthias; Kellner, Christian; Schewe, Denis M.

研究方向

暂未获取到该数据
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M
Martin Stanulla
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G
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H 指数:51论文数:367被引数:1.0万
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Cornelia Eckert
H 指数:48论文数:277被引数:1.0万
M
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H 指数:112论文数:819被引数:4.3万
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H 指数:117论文数:453被引数:11.5万
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V
Viktoras Frismantas
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