Salvatore Spicuglia - Publications, H-index & Citations

Salvatore Spicuglia

tagc

38H指数

186论文数

5.6K被引数

收录论文 63

发表时间

Exonic enhancers are a widespread class of dual-function regulatory elements 外显子增强子是一类广泛的双功能调控元件

Nature Communications

IF15.7

2026-04-02

OAAI

Jean-Christophe Mouren; Magali Torres; Antoinette van Ouwerkerk; Iris Manosalva; Frederic Gallardo; Salvatore Spicuglia; Benoit Ballester

Homeodomain-driven oncogenic diversion to a γδTCR phenotype in T-cell Acute Lymphoblastic Leukemia T细胞急性淋巴细胞白血病中同源域驱动的致癌转移至 γ δ tcr表型

Blood

IF23.1

2026-01-29

PREAI

Antoine Pinton; Lucien Courtois; Manon Delafoy; Mickaël Bonnet; Agata Cieslak; Ludovic Lhermitte; Mathieu Simonin; Marie-Emilie Dourthe; Aurore Touzart; Guillaume P. Andrieu; Hervé Dombret; André Baruchel; Salvatore Spicuglia; Dominique Payet-Bornet; Nicolas Boissel; Elizabeth Macintyre; Vahid Asnafi

Upregulation of ALDH1 as an adaptive epigenetic response to anthracyclines in acute myeloid leukemia ALDH1的上调作为急性髓系白血病对蒽环类药物的适应性表观遗传反应

HemaSphere

IF14.6

2025-10-28

OAAI

Francesco Leonetti; Sladjana Kosanovic; Rocio Rebollidos-Rios; Iris Manosalva; Céline Baier; Muhube Yazir; Andrada Constantinescu; Charbel Souaid; Raquel Pequerul; Miroslava Kari Adamcova; Mehak Shaikh; Magdalena Havlová; Regis Costello; Jaume Farrés; Guillaume Martin; Meritxell Alberich-Jorda; Salvatore Spicuglia; Mileidys Perez-Alea

Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors 乳腺癌中肿瘤间及肿瘤内ALDH1异质性为ALDH1A特异性抑制剂识别出治疗机会

Cell Chemical Biology

IF7.2

2025-09-30

PREAI

Raquel Pequerul; Andrada Constantinescu; Bassam Janji; Akinchan Kumar; Céline Baier; Iris Manosalva; Xavier Parés; Oscar Palacios; Salvatore Spicuglia; Delphine Colignon; Axelle Berrou; Guy Fournet; Paul Berchard; Guillaume Martin; Ismail Ceylan; Rocio Rebollido-Rios; Jaume Farrés; Mileidys Perez-Alea

Unraveling an enhancer-silencer regulatory element showing epistatic interaction with a variant that escaped genome-wide association studies 解析一个与逃脱全基因组关联研究的变异体表现出上位性相互作用的增强子-沉默子调控元件

Cell Genomics

IF9

2025-05-28

OAAI

Mathieu Adjemout; Samia Nisar; Amélie Escandell; Romain Torres; Magali Torres; Hong Thu Nguyen Huu; Alassane Thiam; Iris Manosalva; Babacar Mbengue; Alioune Dieye; Véronique Adoue; Salvatore Spicuglia; Pascal Rihet; Sandrine Marquet

Progressive Elevation of Store-Operated Calcium Entry-Associated Regulatory Factor (SARAF) and Calcium Pathway Dysregulation in Multiple Sclerosis 多发性硬化中与受体操纵性钙离子内流相关的调节因子（SARAF）的进行性升高及钙离子通路失调

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-05-09

OAAI

Taha, Safa; Aljishi, Muna; Sultan, Ameera; Al-Nashmi, Moudi E.; Bakhiet, Moiz; Spicuglia, Salvatore; Belhocine, Mohamed

Comprehensive mapping of genetic variation at Epromoters reveals pleiotropic association with multiple disease traits

NUCLEIC ACIDS RESEARCH

IF13.1

2024-12-27

OAAI

Wan, Jing; van Ouwerkerk, Antoinette; Mouren, Jean-Christophe; Heredia, Carla; Pradel, Lydie; Ballester, Benoit; Andrau, Jean-Christophe; Spicuglia, Salvatore

DNA methylation as a new tool for the differential diagnosis between T-LBL and lymphocyte-rich thymoma

JOURNAL OF PATHOLOGY

IF5.2

2024-09-27

OAAI

Latiri, Mehdi; Belhocine, Mohamed; Smith, Charlotte; Garnier, Nathalie; Balducci, Estelle; Pinton, Antoine; Andrieu, Guillaume P.; Bruneau, Julie; Spicuglia, Salvatore; Jamain, Stephane; Latapie, Violaine; de Montpreville, Vincent Thomas; Chalabreysse, Lara; Marx, Alexander; Girard, Nicolas; Besse, Benjamin; Plass, Christoph; Gibault, Laure; Badoual, Cecile; Macintyre, Elizabeth; Asnafi, Vahid; Molina, Thierry Jo; Touzart, Aurore

Neonatal CD4+ T cells have a characteristic transcriptome and epigenome and respond to TCR stimulation with proliferation and yet a limited immune response

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2023-12-26

PREAI

Kempis-Calanis, Linda Aimara; Rodriguez-Jorge, Otoniel; Gutierrez-Reyna, Darely Yarazeth; Ventura-Martinez, Carlos Jesus; Spicuglia, Salvatore; Medina-Rivera, Alejandra; Thieffry, Denis; Gonzalez, Aitor; Santana, Maria Angelica

Understanding enhancer function to understand human disease

BIOESSAYS

IF2.7

2023-08-29

OAAI

Spicuglia, Salvatore; Rada-Iglesias, Alvaro

G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions

NATURE GENETICS

IF31.8

2023-07-03

OAAI

Esnault, Cyril; Magat, Talha; El Aabidine, Amal Zine; Garcia-Oliver, Encar; Cucchiarini, Anne; Bouchouika, Soumya; Lleres, David; Goerke, Lutz; Luo, Yu; Verga, Daniela; Lacroix, Laurent; Feil, Robert; Spicuglia, Salvatore; Mergny, Jean-Louis; Andrau, Jean-Christophe

Epromoters are new players in the regulatory landscape with potential pleiotropic roles

BIOESSAYS

IF2.7

2023-05-28

OAAI

Malfait, Juliette; Wan, Jing; Spicuglia, Salvatore

Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor α-chain locus

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Yeh, JH; Lecine, P; Nunes, JA; Spicuglia, S; Ferrier, P; Olive, D; Imbert, J

Definition of a T-cell receptor β gene core enhancer of V(D)J recombination by transgenic mapping

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Tripathi, RK; Mathieu, N; Spicuglia, S; Payet, D; Verthuy, C; Bouvier, G; Depetris, D; Mattei, MG; Hempel, WM; Ferrier, P

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Zhou, HQ; Spicuglia, S; Hsieh, JJD; Mitsiou, DJ; Hoiby, T; Veenstra, GJC; Korsmeyer, SJ; Stunnenberg, HG

Short tandem repeats are important contributors to silencer elements in T cells

NUCLEIC ACIDS RESEARCH

IF13.1

2023-03-17

OAAI

Hussain, Saadat; Sadouni, Nori; van Essen, Dominic; Dao, Lan T. M.; Ferre, Quentin; Charbonnier, Guillaume; Torres, Magali; Gallardo, Frederic; Lecellier, Charles-Henri; Sexton, Tom; Saccani, Simona; Spicuglia, Salvatore

TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3' neo-enhancer

HAEMATOLOGICA

IF7.9

2023-01-12

OAAI

Smith, Charlotte; Goyal, Ashish; Weichenhan, Dieter; Allemand, Eric; Mayakonda, Anand; Toprak, Umut; Riedel, Anna; Balducci, Estelle; Manojkumar, Manisha; Pejkovska, Anastasija; Muecke, Oliver; Sollier, Etienne; Bakr, Ali; Breuer, Kersten; Lutsik, Pavlo; Hermine, Olivier; Spicuglia, Salvatore; Asnafi, Vahid; Plass, Christoph; Touzart, Aurore

Current challenges in understanding the role of enhancers in disease 了解增强剂在疾病中的作用的当前挑战

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-12-08

OAAI

Zaugg, Judith Barbara; Sahlen, Pelin; Andersson, Robin; Alberich-Jorda, Meritxell; de Laat, Wouter; Deplancke, Bart; Ferrer, Jorge; Mandrup, Susanne; Natoli, Gioacchino; Plewczynski, Dariusz; Rada-Iglesias, Alvaro; Spicuglia, Salvatore

Severe COVID-19-associated variants linked to chemokine receptor gene control in monocytes and macrophages

GENOME BIOLOGY

IF9.4

2022-04-14

OAAI

Stikker, Bernard S.; Stik, Gregoire; van Ouwerkerk, Antoinette F.; Trap, Lianne; Spicuglia, Salvatore; Hendriks, Rudi W.; Stadhouders, Ralph

Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers

GENOME RESEARCH

IF5.5

2021-12-21

OAAI

Mikulasova, Aneta; Kent, Daniel; Trevisan-Herraz, Marco; Karataraki, Nefeli; Fung, Kent T. M.; Ashby, Cody; Cieslak, Agata; Yaccoby, Shmuel; van Rhee, Frits; Zangari, Maurizio; Thanendrarajan, Sharmilan; Schinke, Carolina; Morgan, Gareth J.; Asnafi, Vahid; Spicuglia, Salvatore; Brackley, Chris A.; Corcoran, Anne E.; Hambleton, Sophie; Walker, Brian A.; Rico, Daniel; Russell, Lisa J.

研究方向