Le Cong - Publications, H-index & Citations

Le Cong

stanford university school of medicine

40H指数

140论文数

3.0W被引数

收录论文 31

发表时间

Surfaceome CRISPR activation screening uncovers ligands regulating tumor sensitivity to NK cell killing 表面组CRISPR激活筛选揭示调控肿瘤对NK细胞杀伤敏感性的配体

Nature Communications

IF15.7

2026-08-06

OAAI

Ravi K. Dinesh; Xiaotong Wang; Imran A. Mohammad; Pari Gunasekaran; Kostas Stiklioraitis; Jeremy R. Villafuerte; Anirudh Rao; Rogelio A. Hernandez-Lopez; John B. Sunwoo; Le Cong

Programmable RNA translation through deep learning-driven IRES discovery and de novo generation 通过深度学习驱动的IRES发现和从头生成实现可编程RNA翻译

Nature Machine Intelligence

IF23.9

2026-04-24

PREAI

Yanyi Chu; Di Yin; Dan Yu; Guangxue Xu; Junze Zhang; Xiaotong Wang; Yue Shen; Yupeng Li; Ning Zhao; Yi Zhu; Jason Zhang; Hani Goodarzi; Mengdi Wang; Le Cong

Motion Planning of Mobile Robots in Dynamic Environments with Neural Network Based on Dynamic Window Approach 基于动态窗口法及神经网络的动态环境下移动机器人运动规划

MULTI-DISCIPLINARY TRENDS IN ARTIFICIAL INTELLIGENCE, MIWAI 2025, PT III

IF0

2026-01-01

PREAI

Mai The Anh; Le Thai An; Dang Thai Son; Ta Hung Cuong; Dinh Van Nam; Le Dinh Cong; Nguyen Quang Hai

Publisher Correction: CRISPR-GPT for agentic automation of gene-editing experiments 出版商更正：CRISPR-GPT 用于代理式自动化基因编辑实验

Nature Biomedical Engineering

IF26.6

2025-12-08

OAAI

Yuanhao Qu; Kaixuan Huang; Ming Yin; Kanghong Zhan; Dyllan Liu; Di Yin; Henry C. Cousins; William A. Johnson; Xiaotong Wang; Mihir Shah; Russ B. Altman; Denny Zhou; Mengdi Wang; Le Cong

CRISPR-GPT for agentic automation of gene-editing experiments CRISPR-GPT用于基因编辑实验的代理自动化

Nature Biomedical Engineering

IF26.6

2025-07-30

OAAI

Yuanhao Qu; Kaixuan Huang; Ming Yin; Kanghong Zhan; Dyllan Liu; Di Yin; Henry C. Cousins; William A. Johnson; Xiaotong Wang; Mihir Shah; Russ B. Altman; Denny Zhou; Mengdi Wang; Le Cong

Computationally guided high-throughput engineering of an anti-CRISPR protein for precise genome editing in human cells

CELL REPORTS METHODS

IF4.5

2024-10-01

OAAI

Marsiglia, Julia; Vaalavirta, Kia; Knight, Estefany; Nakamura, Muneaki; Cong, Le; Hughes, Nicholas W.

A 5′ UTR language model for decoding untranslated regions of mRNA and function predictions (vol 6, pg 449, 2024)

NATURE MACHINE INTELLIGENCE

IF23.9

2024-08-02

OAAI

Chu, Yanyi; Yu, Dan; Li, Yupeng; Huang, Kaixuan; Shen, Yue; Cong, Le; Zhang, Jason; Wang, Mengdi

A 5′ UTR language model for decoding untranslated regions of mRNA and function predictions

NATURE MACHINE INTELLIGENCE

IF23.9

2024-04-05

OAAI

Chu, Yanyi; Yu, Dan; Li, Yupeng; Huang, Kaixuan; Shen, Yue; Cong, Le; Zhang, Jason; Wang, Mengdi

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology

NEURON

IF15

2024-04-01

OAAI

Chemparathy, Augustine; Guen, Yann Le; Chen, Sunny; Lee, Eun-Gyung; Leong, Lesley; Gorzynski, John E.; Jensen, Tanner D.; Ferrasse, Alexis; Xu, Guangxue; Xiang, Hong; Belloy, Michael E.; Kasireddy, Nandita; Pena-Tauber, Andres; Williams, Kennedy; Stewart, Ilaria; Talozzi, Lia; Wingo, Thomas S.; Lah, James J.; Jayadev, Suman; Hales, Chadwick M.; Peskind, Elaine; Child, Daniel D.; Roeber, Sigrun; Keene, C. Dirk; Cong, Le; Ashley, Euan A.; Yu, Chang -En; Greicius, Michael D.

The initiation and progression of pancreatic ductal adenocarcinoma through a p53 lens

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Hanson, Kathryn J.; Minor, Allegra C.; Flowers, Brittany M.; Kaiser, Alyssa M.; Hughes, Nicholas; Vogel, Hannes; Cong, Le; Attardi, Laura D.

Integrative analysis of functional genomic screening and clinical data identifies a protective role for spironolactone in severe COVID-19

CELL REPORTS METHODS

IF4.5

2023-07-01

OAAI

Cousins, Henry C.; Kline, Adrienne Sarah; Wang, Chengkun; Qu, Yuanhao; Zengel, James; Carette, Jan; Wang, Mengdi; Altman, Russ B.; Luo, Yuan; Cong, Le

Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes

NEURON

IF15

2022-08-01

OAAI

Li, Liang; Fang, Fang; Feng, Xue; Zhuang, Pei; Huang, Haoliang; Liu, Pingting; Liu, Liang; Xu, Adam Z.; Qi, Lei S.; Cong, Le; Hu, Yang

Machine-learning-optimized Cas12a barcoding enables the recovery of single-cell lineages and transcriptional profiles

MOLECULAR CELL

IF16.6

2022-08-01

OAAI

Hughes, Nicholas W.; Qu, Yuanhao; Zhang, Jiaqi; Tang, Weijing; Pierce, Justin; Wang, Chengkun; Agrawal, Aditi; Morri, Maurizio; Neff, Norma; Winslow, Monte M.; Wang, Mengdi; Cong, Le

Editorial: CRISPR and alternative approaches

BIOTECHNOLOGY JOURNAL

IF3.1

2022-06-21

PREAI

Kapusi, Eszter; Cong, Le; Stoger, Eva

dCas9-based gene editing for cleavage-free genomic knock-in of long sequences

NATURE CELL BIOLOGY

IF19.1

2022-02-10

OAAI

Wang, Chengkun; Qu, Yuanhao; Cheng, Jason K. W.; Hughes, Nicholas W.; Zhang, Qianhe; Wang, Mengdi; Cong, Le

Deciphering pathogenicity of variants of uncertain significance with CRISPR-edited iPSCs

TRENDS IN GENETICS

IF16.3

2021-12-01

OAAI

Guo, Hongchao; Liu, Lichao; Nishiga, Masataka; Cong, Le; Wu, Joseph C.

Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes 常规I型树突状细胞在肿瘤引流淋巴结中维持增殖性肿瘤抗原特异性TCF-1 CD8 T细胞库

IMMUNITY

IF26.3

2021-10-01

154

OAAI

Schenkel, Jason M.; Herbst, Rebecca H.; Canner, David; Li, Amy; Hillman, Michelle; Shanahan, Sean-Luc; Gibbons, Grace; Smith, Olivia C.; Kim, Jonathan Y.; Westcott, Peter; Hwang, William L.; Freed-Pastor, William A.; Eng, George; Cuoco, Michael S.; Rogers, Patricia; Park, Jin K.; Burger, Megan L.; Rozenblatt-Rosen, Orit; Cong, Le; Pauken, Kristen E.; Regev, Aviv; Jacks, Tyler

A CRISPR Landing for Genome Rewriting at Locus-Scale

CRISPR JOURNAL

IF4

2021-04-01

OAAI

Hughes, Nicholas W.; Cong, Le

Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects 微生物单链退火蛋白使CRISPR基因编辑工具具有更高的敲入效率和更低的脱靶效应

NUCLEIC ACIDS RESEARCH

IF13.1

2021-02-22

OAAI

Wang, Chengkun; Cheng, Jason K. W.; Zhang, Qianhe; Hughes, Nicholas W.; Xia, Qiong; Winslow, Monte M.; Cong, Le

A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer

CANCER DISCOVERY

IF33.3

2021-02-19

OAAI

Cai, Hongchen; Chew, Su Kit; Li, Chuan; Tsai, Min K.; Andrejka, Laura; Murray, Christopher W.; Hughes, Nicholas W.; Shuldiner, Emily G.; Ashkin, Emily L.; Tang, Rui; Hung, King L.; Chen, Leo C.; Lee, Shi Ya C.; Yousefi, Maryam; Lin, Wen-Yang; Kunder, Christian A.; Cong, Le; McFarland, Christopher D.; Petrov, Dmitri A.; Swanton, Charles; Winslow, Monte M.

研究方向