logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
T

Tyler Jacks

Howard Hughes Medical Institute
H指数:158
被引数:12.5万

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Lineage identity governs oncogene dependence in mouse NSCLC models of KRAS inhibitor resistance

谱系身份调控小鼠KRAS抑制剂耐药性非小细胞肺癌模型中的癌基因依赖性

Nature Genetics
IF29
2026-09-300
PRE
Nicolas Mathey-Andrews; Carrie L. Rodriguez; Bing Shui; Agata L. Patriotis; William M. Rideout; Victor Z. Chen; Ileana Murazzi; Phaedra Ghazi; Milton R. Cornwall-Brady; Manyuan Liu; Morgan G. Heileman; Marianna Trakala; Carla P. Concepcion-Crisol; Dian Yang; Tyler Jacks
Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis

空间谱系示踪揭示了肿瘤生长和转移的动态空间架构

Nature Genetics
IF29
2026-09-020
PRE
Matthew G. Jones; Dawei Sun; Kyung Hoi Joseph Min; William N. Colgan; Haoyu Wang; Tivadar Török; Juliano Ribeiro; Jessie Xue; Erik C. Cardoso; Yao Rong; Luyi Tian; Jackson A. Weir; Victor Z. Chen; Luke W. Koblan; Kathryn E. Yost; Nicolas Mathey-Andrews; Edridge D’Souza; Andrew J. C. Russell; Robert R. Stickels; Karol S. Balderrama; William M. Rideout; Min Dai; Giovanni Marrero; Vipin Kumar; Anjali Saqi; Benjamin Herzberg; Benjamin Izar; Howard Y. Chang; Joo-Hyeon Lee; Tyler Jacks; Fei Chen; Jonathan S. Weissman; Nir Yosef; Dian Yang
Pancreatic cancer-restricted cryptic antigens are targets for T cell recognition

胰腺癌特异性隐蔽抗原是T细胞识别的靶点

SCIENCE
IF45.8
2025-05-080
PRE
Ely, Zackery A.; Kulstad, Zachary J.; Gunaydin, Gurcan; Addepalli, Sudarsana; Verzani, Eva K.; Casarrubios, Marta; Clauser, Karl R.; Wang, Xilin; Lippincott, Isabelle E.; Louvet, Cedric; Schmitt, Thomas; Kapner, Kevin S.; Agus, Miles P.; Hennessey, Connor J.; Cleary, James M.; Hadrup, Sine R.; Klaeger, Susan; Su, Jennifer; Jaeger, Alex M.; Wolpin, Brian M.; Raghavan, Srivatsan; Smith, Eric L.; Greenberg, Philip D.; Aguirre, Andrew J.; Abelin, Jennifer G.; Carr, Steven A.; Jacks, Tyler; Freed-Pastor, William A.
Intrinsic electrical activity drives small-cell lung cancer progression

固有电活动驱动小细胞肺癌进展

NATURE
IF48.5
2025-02-123
OA
Peinado, Paola; Stazi, Marco; Ballabio, Claudio; Margineanu, Michael-Bogdan; Li, Zhaoqi; Colon, Caterina I.; Hsieh, Min-Shu; Pal Choudhuri, Shreoshi; Stastny, Victor; Hamilton, Seth; Le Marois, Alix; Collingridge, Jodie; Conrad, Linus; Chen, Yinxing; Ng, Sheng Rong; Magendantz, Margaret; Bhutkar, Arjun; Chen, Jin-Shing; Sahai, Erik; Drapkin, Benjamin J.; Jacks, Tyler; Vander Heiden, Matthew G.; Kopanitsa, Maksym V.; Robinson, Hugh P. C.; Li, Leanne
Discovery and therapeutic potential of novel cryptic peptides in pancreatic cancer
CANCER RESEARCH
IF16.6
2024-09-150
PRE
Ely, Zackery A.; Kulstad, Zachary J.; Gunaydin, Gurcan; Addepalli, Sudarsana; Verzani, Eva K.; Abelin, Jennifer G.; Casarrubios, Marta; Clauser, Karl R.; Wang, Xilin; Lippincott, Isabelle; Louvet, Cedric; Schmitt, Tom; Agus, Miles; Kapner, Kevin S.; Hennessey, Connor J.; Cleary, James; Hadrup, Sine R.; Klaeger, Susan; Su, Jennifer; Jaeger, Alex M.; Wolpin, Brian M.; Raghavan, Srivatsan; Smith, Eric; Greenberg, Philip D.; Aguirre, Andrew J.; Carr, Steven A.; Jacks, Tyler; Freed-Pastor, William A.
Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment

胰腺癌的空间分辨分析确定了肿瘤微环境的治疗相关重塑

NATURE GENETICS
IF31.8
2024-09-031
PRE
Shiau, Carina; Cao, Jingyi; Gong, Dennis; Gregory, Mark T.; Caldwell, Nicholas J.; Yin, Xunqin; Cho, Jae-Won; Wang, Peter L.; Su, Jennifer; Wang, Steven; Reeves, Jason W.; Kim, Tae Kyung; Kim, Youngmi; Guo, Jimmy A.; Lester, Nicole A.; Bae, Jung Woo; Zhao, Ryan; Schurman, Nathan; Barth, Jamie L.; Ganci, Maria L.; Weissleder, Ralph; Jacks, Tyler; Qadan, Motaz; Hong, Theodore S.; Wo, Jennifer Y.; Roberts, Hannah; Beechem, Joseph M.; Fernandez-del Castillo, Carlos; Mino-Kenudson, Mari; Ting, David T.; Hemberg, Martin; Hwang, William L.
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma (vol 21, pg 1163, 2015)

BET家族蛋白和组蛋白去乙酰化酶的联合抑制作为胰腺导管腺癌的潜在的基于表观遗传学的疗法 (第21卷，1163页，2015)

NATURE MEDICINE
IF50
2024-05-300
OA
Mazur, Pawel K.; Herner, Alexander; Mello, Stephano S.; Wirth, Matthias; Hausmann, Simone; Sanchez-Rivera, Francisco J.; Lofgren, Shane M.; Kuschma, Timo; Hahn, Stephan A.; Vangala, Deepak; Trajkovic-Arsic, Marija; Gupta, Aayush; Heid, Irina; Noeel, Peter B.; Braren, Rickmer; Erkan, Mert; Kleeff, Joerg; Sipos, Bence; Sayles, Leanne C.; Heikenwalder, Mathias; Hessmann, Elisabeth; Ellenrieder, Volker; Esposito, Irene; Jacks, Tyler; Bradner, James E.; Khatri, Purvesh; Sweet-Cordero, E. Alejandro; Attardi, Laura D.; Schmid, Roland M.; Schneider, Guenter; Sage, Julien; Siveke, Jens T.
Deciphering cell states and genealogies of human haematopoiesis

破译人类造血的细胞状态和家谱

Nature
IF48.5
2024-01-220
OAAI
Chen Weng; Fulong Yu; Dian Yang; Michael Poeschla; L. Alexander Liggett; Matthew G. Jones; Xiaojie Qiu; Lara Wahlster; Alexis Caulier; Jeffrey A. Hussmann; Alexandra Schnell; Kathryn E. Yost; Luke W. Koblan; Jorge D. Martin-Rufino; Joseph Min; Alessandro Hammond; Daniel Ssozi; Raphael Bueno; Hari Mallidi; Antonia Kreso; Javier Escabi; William M. Rideout; Tyler Jacks; Sahand Hormoz; Peter van Galen; Jonathan S. Weissman; Vijay G. Sankaran
Non-canonical MHC class I-associated antigens in pancreatic cancer
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Ely, Zackery A.; Kulstad, Zachary J.; Verzani, Eva K.; Abelin, Jennifer G.; Addepalli, Sudarsana; Clauser, Karl R.; Casarrubios, Marta; Kapner, Kevin S.; Agus, Miles P.; Hennessey, Connor J.; Hadrup, Sine R.; Klaeger, Susan; Su, Jennifer; Jaeger, Alex M.; Wolpin, Brian M.; Raghavan, Srivatsan; Greenberg, Philip D.; Aguirre, Andrew J.; Carr, Steven A.; Jacks, Tyler; Freed-Pastor, William A.
Spatially-constrained optimal transport interaction analysis reveals therapy-associated remodeling in the pancreatic cancer microenvironment
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Shiau, Carina; Cao, Jingyi; Gregory, Mark T.; Gong, Dennis; Yin, Xunqin; Cho, Jae-Won; Wang, Peter L.; Su, Jennifer; Wang, Steven; Reeves, Jason W.; Kim, Tae Kyung; Kim, Youngmi; Guo, Jimmy A.; Lester, Nicole A.; Barth, Jamie L.; Jacks, Tyler; Hong, Theodore S.; Beechem, Joseph M.; Fernandez-del Castillo, Carlos; Mino-Kenudson, Mari; Ting, David T.; Hemberg, Martin; Hwang, William L.
Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity

错配修复缺陷不足以引起肿瘤免疫原性

NATURE GENETICS
IF31.8
2023-09-1446
OAAI
Westcott, Peter M. K.; Muyas, Francesc; Hauck, Haley; Smith, Olivia C.; Sacks, Nathan J.; Ely, Zackery A.; Jaeger, Alex M.; Rideout, William M., III; Zhang, Daniel; Bhutkar, Arjun; Beytagh, Mary C.; Canner, David A.; Jaramillo, Grissel C.; Bronson, Roderick T.; Naranjo, Santiago; Jin, Abbey; Patten, J. J.; Cruz, Amanda M.; Shanahan, Sean-Luc; Cortes-Ciriano, Isidro; Jacks, Tyler
A prime editor mouse to model a broad spectrum of somatic mutations in vivo

prime editor小鼠在体内建立广泛的体细胞突变模型

NATURE BIOTECHNOLOGY
IF41.7
2023-05-1120
OA
Ely, Zackery A.; Mathey-Andrews, Nicolas; Naranjo, Santiago; Gould, Samuel I.; Mercer, Kim L.; Newby, Gregory A.; Cabana, Christina M.; Rideout III, William M.; Jaramillo, Grissel Cervantes; Khirallah, Jennifer M.; Holland, Katie; Randolph, Peyton B.; Freed-Pastor, William A.; Davis, Jessie R.; Kulstad, Zachary; Westcott, Peter M. K.; Lin, Lin; Anzalone, Andrew V.; Horton, Brendan L.; Pattada, Nimisha B.; Shanahan, Sean-Luc; Ye, Zhongfeng; Spranger, Stefani; Xu, Qiaobing; Sanchez-Rivera, Francisco J.; Liu, David R.; Jacks, Tyler
Lung adenocarcinoma promotion by air pollutants

空气污染物对肺腺癌的促进作用

Nature
IF48.5
2023-04-050
PREAI
William Hill; Emilia L. Lim; Clare E. Weeden; Claudia Lee; Marcellus Augustine; Kezhong Chen; Feng-Che Kuan; Fabio Marongiu; Edward J. Evans; David A. Moore; Felipe S. Rodrigues; Oriol Pich; Bjorn Bakker; Hongui Cha; Renelle Myers; Febe van Maldegem; Jesse Boumelha; Selvaraju Veeriah; Andrew Rowan; Cristina Naceur-Lombardelli; Takahiro Karasaki; Monica Sivakumar; Swapnanil De; Deborah R. Caswell; Ai Nagano; James R. M. Black; Carlos Martínez-Ruiz; Min Hyung Ryu; Ryan D. Huff; Shijia Li; Marie-Julie Favé; Alastair Magness; Alejandro Suárez-Bonnet; Simon L. Priestnall; Margreet Lüchtenborg; Katrina Lavelle; Joanna Pethick; Steven Hardy; Fiona E. McRonald; Meng-Hung Lin; Clara I. Troccoli; Moumita Ghosh; York E. Miller; Daniel T. Merrick; Robert L. Keith; Maise Al Bakir; Chris Bailey; Mark S. Hill; Lao H. Saal; Yilun Chen; Anthony M. George; Christopher Abbosh; Nnennaya Kanu; Se-Hoon Lee; Nicholas McGranahan; Christine D. Berg; Peter Sasieni; Richard Houlston; Clare Turnbull; Stephen Lam; Philip Awadalla; Eva Grönroos; Julian Downward; Tyler Jacks; Christopher Carlsten; Ilaria Malanchi; Allan Hackshaw; Kevin Litchfield; James DeGregori; Mariam Jamal-Hanjani; Charles Swanton

研究方向

暂未获取到该数据
A
Arjun Bhutkar
H 指数:43论文数:237被引数:1.0万
R
Roderick T. Bronson
H 指数:164论文数:1,099被引数:10.9万
F
Francisco J. Sánchez‐Rivera
H 指数:36论文数:188被引数:7,042
T
Tuomas Tammela
H 指数:52论文数:222被引数:1.6万
P
Peter M.K. Westcott
H 指数:20论文数:78被引数:2,669
M
Matthew G. Vander Heiden
H 指数:119论文数:700被引数:9.1万
D
Denise Crowley
H 指数:40论文数:103被引数:1.8万
M
Mary C. Beytagh
H 指数:8论文数:71被引数:754
M
Monte M. Winslow
H 指数:55论文数:375被引数:1.3万
Ö
Ömer Yılmaz
H 指数:69论文数:832被引数:2.5万