Clarissa Gerhäuser - Publications, H-index & Citations

Clarissa Gerhäuser

german cancer research center

62H指数

215论文数

2.4W被引数

收录论文 47

发表时间

Recurrent mechanisms of biallelic epigenetic inactivation reveal new putative tumour suppressor genes in prostate cancer 前列腺癌中双等位基因表观遗传失活的复发机制揭示了新的潜在肿瘤抑制基因

Nature Communications

IF15.7

2026-09-09

OAAI

Daria Kiriy; Francesco Favero; Clarissa Gerhäuser; Jessica Heilmann; Pavlo Lutsik; Francisco German Rodriguez Gonzalez; Alessio Locallo; Jakob Schmidt Jespersen; Andreas J. Gruber; Andre V. Olsen; Barbara Hernando; Kevin CL Cheng; Diogo Pellegrina; Geoff Macintyre; G. Steven Bova; Daniel S. Brewer; Robert G. Bristow; Mark N. Brook; Benedikt Brors; Adam Butler; Géraldine Cancel-Tassin; Niall M. Corcoran; Olivier Cussenot; Ros A. Eeles; Abraham Gihawi; Etsehiwot G. Girma; Vincent J. Gnanapragasam; Anis Hamid; Vanessa M. Hayes; Housheng Hansen He; Christopher M. Hovens; Eddie L. Imada; G. Maria Jakobsdottir; Chol-Hee Jung; Francesca Khani; Zsofia Kote-Jarai; Philippe P. Lamy; Gregory Leeman; Massimo Loda; Luigi Marchionni; Ramyar Molania; Anthony T. Papenfuss; Bernard Pope; Lucio R. Queiroz; Tobias Rausch; Brian Robinson; Atef Sahli; Karina D. Sørensen; Sebastian Uhrig; David C. Wedge; Yaobo Xu; Takafumi N. Yamaguchi; Claudio Zanettini; Colin S. Cooper; Thorsten Schlomm; Jüri Reimand; Joachim Weischenfeldt

Integrated signatures define mutational processes in prostate cancer 整合特征定义前列腺癌中的突变过程

Nature

IF48.5

2026-09-09

OAAI

Andreas J. Gruber; André V. Olsen; Barbara Hernando; Kevin C. L. Cheng; Clarissa Gerhäuser; Marina Torres; Francesco Favero; Daria Kiriy; Ángel Fernández-Sanromán; Juan Maria Roldan-Romero; Lucy Barton; Diogo Pellegrina; G. Steven Bova; Daniel S. Brewer; Mark N. Brook; Benedikt Brors; Adam Butler; Géraldine Cancel-Tassin; Niall M. Corcoran; Olivier Cussenot; Abraham Gihawi; Etsehiwot G. Girma; Vincent J. Gnanapragasam; Anis A. Hamid; Vanessa M. Hayes; Housheng Hansen He; Christopher M. Hovens; Eddie L. Imada; G. Maria Jakobsdottir; Chol-Hee Jung; Francesca Khani; Zsofia Kote-Jarai; Philippe Lamy; Gregory Leeman; Massimo Loda; Pavlo Lutsik; Luigi Marchionni; Ramyar Molania; Anthony T. Papenfuss; Bernard Pope; Lucio R. Queiroz; Tobias Rausch; Brian Robinson; Atef Sahli; Karina D. Sørensen; Takafumi N. Yamaguchi; Sebastian Uhrig; Yaobo Xu; Claudio Zanettini; Ronald Simon; Guido Sauter; Ros A. Eeles; Colin S. Cooper; Robert G. Bristow; David C. Wedge; Thorsten Schlomm; Geoff Macintyre; Jüri Reimand; Joachim Weischenfeldt

Clonal evolution and transcriptional plasticity shape metastatic dissemination routes in prostate cancer 克隆演化和转录可塑性塑造了前列腺癌的转移播散途径

Nature Communications

IF15.7

2025-12-23

OAAI

Migle Mikutenaite; Evdoxia Karadoulama; Francesco Favero; Alessio Locallo; Francisco German Rodriguez Gonzalez; Daria Kiriy; Tina Keshavarzian; Kira Furlano; Markus Graefen; Robert G. Bristow; Clarissa Gerhäuser; Christoph Plass; Guido Sauter; Ronald Simon; Mathieu Lupien; Sarah Minner; Thorsten Schlomm; Joachim Weischenfeldt

Prostate cancer cells converge to an inflammatory-like state upon metastatic dissemination 前列腺癌细胞在发生转移性播散时趋近于一种炎症样状态。

Nature Communications

IF15.7

2025-12-23

OAAI

Tina Keshavarzian; Kira Furlano; Giacomo Grillo; Lisanne Mout; Christopher Arlidge; Faizan Hasan; Ankita Nand; Migle Mikutenaite; Evdoxia Karadoulama; Ashish Goyal; Elisabeth L. Pezzuto; Jessica Heilmann; Jakub Sykora; Sarah Minner; Thorsten Schlomm; Guido Sauter; Ronald Simon; Housheng Hansen He; Joachim Weischenfeldt; Christoph Plass; Clarissa Gerhäuser; Mathieu Lupien

Integrative analysis of RNA expression signatures and recurrent genomic alterations before treatment: link to menopausal status, short-term endocrine therapy response and disease-free survival in luminal breast cancer RNA表达特征与复发基因组改变的整合分析：治疗前与绝经状态、短期内分泌治疗反应及无病生存期的关联性研究（在腔面乳腺癌中）

ESMO Open

IF8.3

2025-11-21

OAAI

G. Zhang; H. Ni; L. Mishieva; S. Bartels; M. Christgen; H. Christgen; L.D. Kandt; M. Raap; R.E. Kates; O. Gluz; M. Graeser; S. Kümmel; U. Nitz; C. Plass; U. Mansmann; C. zu Eulenburg; C. Gerhäuser; H.H. Kreipe; N. Harbeck

Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard Pipeline Olympics：针对DNA甲基化测序数据，基于实验金标准的可延续性计算工作流基准测试

NUCLEIC ACIDS RESEARCH

IF13.1

2025-10-28

OAAI

Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo

A predictive endocrine resistance index accurately stratifies luminal breast cancer treatment responders and nonresponders 一个预测性内分泌抵抗指数能够准确地对腔面型乳腺癌治疗反应者和非反应者进行分层。

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2025-10-01

OAAI

Zhang, Guokun; Jurinovic, Vindi; Bartels, Stephan; Christgen, Matthias; Christgen, Henriette; Kandt, Leonie Donata; Mishieva, Lidiya; Ni, Hua; Raap, Mieke; Klein, Janin; Katzke, Anna-Lena; Hofmann, Winfried; Steinemann, Doris; Kates, Ronald E.; Gluz, Oleg; Graeser, Monika; Kummel, Sherko; Nitz, Ulrike; Plass, Christoph; Lehmann, Ulrich; Eulenburg, Christine zu; Mansmann, Ulrich; Gerhauser, Clarissa; Harbeck, Nadia; Kreipe, Hans H.

EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells EpiCRISPR靶向Arx基因的甲基化启动小鼠胰腺 α 向胰岛素产生细胞的瞬时转换

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2023-03-16

OAAI

Dordevic, Marija; Stepper, Peter; Feuerstein-Akgoz, Clarissa; Gerhauser, Clarissa; Paunovic, Verica; Tolic, Anja; Rajic, Jovana; Dinic, Svetlana; Uskokovic, Aleksandra; Grdovic, Nevena; Mihailovic, Mirjana; Jurkowska, Renata Z.; Jurkowski, Tomasz P.; Jovanovic, Jelena Arambasic; Vidakovic, Melita

DNA methylation biomarkers for noninvasive detection of triple-negative breast cancer using liquid biopsy 使用液体活检对三阴性乳腺癌进行无创检测的DNA甲基化生物标志物

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2022-11-08

OAAI

Manoochehri, Mehdi; Borhani, Nasim; Gerhaeuser, Clarissa; Assenov, Yassen; Schoenung, Maximilian; Hielscher, Thomas; Christensen, Brock C.; Lee, Min Kyung; Grone, Hermann-Josef; Lipka, Daniel B.; Bruening, Thomas; Brauch, Hiltrud; Ko, Yon-Dschun; Hamann, Ute

A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation

NATURE COMMUNICATIONS

IF15.7

2022-04-19

OAAI

Llimos, Gerard; Gardeux, Vincent; Koch, Ute; Kribelbauer, Judith F.; Hafner, Antonina; Alpern, Daniel; Pezoldt, Joern; Litovchenko, Maria; Russeil, Julie; Dainese, Riccardo; Moia, Riccardo; Mahmoud, Abdurraouf Mokhtar; Rossi, Davide; Gaidano, Gianluca; Plass, Christoph; Lutsik, Pavlo; Gerhauser, Clarissa; Waszak, Sebastian M.; Boettiger, Alistair; Radtke, Freddy; Deplancke, Bart

Epigenetic quantification of circulating immune cells in peripheral blood of triple-negative breast cancer patients

CLINICAL EPIGENETICS

IF4.4

2021-11-17

OAAI

Manoochehri, Mehdi; Hielscher, Thomas; Borhani, Nasim; Gerhaeuser, Clarissa; Fletcher, Olivia; Swerdlow, Anthony J.; Ko, Yon-Dschun; Brauch, Hiltrud; Bruening, Thomas; Hamann, Ute

Random forest-based modelling to detect biomarkers for prostate cancer progression 基于随机森林的建模检测前列腺癌进展的生物标志物

CLINICAL EPIGENETICS

IF4.4

2019-10-22

OAAI

Toth, Reka; Schiffmann, Heiko; Hube-Magg, Claudia; Buescheck, Franziska; Hoeflmayer, Doris; Weidemann, Soeren; Lebok, Patrick; Fraune, Christoph; Minner, Sarah; Schlomm, Thorsten; Sauter, Guido; Plass, Christoph; Assenov, Yassen; Simon, Ronald; Meiners, Jan; Gerhaeuser, Clarissa

A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites

SCIENTIFIC REPORTS

IF3.9

2018-10-19

OAAI

Milenkovic, Dragan; Vanden Berghe, Wim; Morand, Christine; Claude, Sylvain; van de Sandt, Annette; Gorressen, Simone; Monfoulet, Laurent-Emmanuel; Chirumamilla, Chandra S.; Declerck, Ken; Szic, Katarzyna Szarc Vel; Lahtela-Kakkonen, Maija; Gerhauser, Clarissa; Merx, Marc W.; Kelm, Malte

Intratumor heterogeneity in epigenetic patterns

SEMINARS IN CANCER BIOLOGY

IF15.7

2018-08-01

OAAI

Assenov, Yassen; Brocks, David; Gerhaeuser, Clarissa

Impact of dietary gut microbial metabolites on the epigenome 膳食肠道微生物代谢产物对表观基因组的影响

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2018-04-23

OAAI

Gerhauser, Clarissa

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats (vol 49, pg 1052, 2017)

NATURE GENETICS

IF31.8

2017-11-01

OAAI

Brocks, David; Schmidt, Christopher R.; Daskalakis, Michael; Jang, Hyo Sik; Shah, Nakul M.; Li, Daofeng; Li, Jing; Zhang, Bo; Hou, Yiran; Laudato, Sara; Lipka, Daniel B.; Schott, Johanna; Bierhoff, Holger; Assenov, Yassen; Helf, Monika; Ressnerova, Alzbeta; Islam, Md Saiful; Lindroth, Anders M.; Haas, Simon; Essers, Marieke; Imbusch, Charles D.; Brors, Benedikt; Oehme, Ina; Witt, Olaf; Lubbert, Michael; Mallm, Jan-Philipp; Rippe, Karsten; Will, Rainer; Weichenhan, Dieter; Stoecklin, Georg; Gerhauser, Clarissa; Oakes, Christopher C.; Wang, Ting; Plass, Christoph

Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer

ONCOGENE

IF7.3

2017-07-31

OAAI

Heilmann, K.; Toth, R.; Bossmann, C.; Klimo, K.; Plass, C.; Gerhauser, C.

Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease

SCIENTIFIC REPORTS

IF3.9

2017-07-11

OAAI

Istas, Geoffrey; Declerck, Ken; Pudenz, Maria; Szic, Katarzyna Szarc Vel; Lendinez-Tortajada, Veronica; Leon-Latre, Montserrat; Heyninck, Karen; Haegeman, Guy; Casasnovas, Jose A.; Tellez-Plaza, Maria; Gerhauser, Clarissa; Heiss, Christian; Rodriguez-Mateos, Ana; Vanden Berghe, Wim

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

NATURE GENETICS

IF31.8

2017-06-12

235

OAAI

Brocks, David; Schmidt, Christopher R.; Daskalakis, Michael; Jang, Hyo Sik; Shah, Nakul M.; Li, Daofeng; Li, Jing; Zhang, Bo; Hou, Yiran; Laudato, Sara; Lipka, Daniel B.; Schott, Johanna; Bierhoff, Holger; Assenov, Yassen; Helf, Monika; Ressnerova, Alzbeta; Islam, Md Saiful; Lindroth, Anders M.; Haas, Simon; Essers, Marieke; Imbusch, Charles D.; Brors, Benedikt; Oehme, Ina; Witt, Olaf; Luebbert, Michael; Mallm, Jan-Philipp; Rippe, Karsten; Will, Rainer; Weichenhan, Dieter; Stoecklin, Georg; Gerhaeuser, Clarissa; Oakes, Christopher C.; Wang, Ting; Plass, Christoph

Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer ER阳性乳腺癌中启动子高甲基化抑制indoleamine-2，3-双加氧酶1的表达

ONCOIMMUNOLOGY

IF6.3

2017-02-07

OAAI

Dewi, Dyah L.; Mohapatra, Soumya R.; Cabanes, Saioa Blanco; Adam, Isabell; Patterson, Luis F. Somarribas; Berdel, Bianca; Kahloon, Masroor; Thuemann, Loreen; Loth, Stefanie; Heilmann, Katharina; Weichenhan, Dieter; Muecke, Oliver; Heiland, Ines; Wimberger, Pauline; Kuhlmann, Jan Dominik; Kellner, Karl-Heinz; Schott, Sarah; Plass, Christoph; Platten, Michael; Gerhaeuser, Clarissa; Trump, Saskia; Opitz, Christiane A.

研究方向