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C

Chase L. Beisel

helmholtz association

45H指数
157论文数
7.3K被引数
收录论文 75
发表时间
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Guide DNA — not RNA — expands the CRISPR toolkit指导DNA-而不是RNA-扩展了CRISPR工具包
errNature Biotechnology
IF41.7
err2026-05-15
err0
PREAI
errChase L. Beisel
err分享
err收藏
RNA-triggered cell killing with CRISPR–Cas12a2CRISPR–Cas12a2介导的RNA触发细胞杀伤
errNature
IF48.5
err2026-05-06
err0
errOAAI
errPaul Scholz; Jared Thompson; Kadin T. Crosby; Torsten Fauth; Nathan M. Krah; Grant Schlauderaff; Robin Back; Zachary A. Berkheimer; Alivia Jolley; Dirk Sombroek; Rebekka Medert; Christian Zurek; Oleg Dmytrenko; Emily Wilson; Friso T. Schut; Jared Rutter; Xiaoyang Zhang; Michael Krohn; Ryan N. Jackson; Chase L. Beisel; Yang Liu
err分享
err收藏
RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunityRNA触发的Cas12a3切割tRNA尾部以执行细菌免疫。
errNature
IF48.5
err2026-01-07
err0
errOAAI
errOleg Dmytrenko; Biao Yuan; Kadin T. Crosby; Max Krebel; Xiye Chen; Jakub S. Nowak; Andrzej Chramiec-Głąbik; Bamidele Filani; Anne-Sophie Gribling-Burrer; Wiep van der Toorn; Max von Kleist; Tatjana Achmedov; Redmond P. Smyth; Sebastian Glatt; Jack P. K. Bravo; Dirk W. Heinz; Ryan N. Jackson; Chase L. Beisel
err分享
err收藏
Comprehensive analysis of CRISPR array repeat mutations reveals subtype-specific patterns and links to spacer dynamicsCRISPR阵列重复序列突变的综合分析揭示了与间隔序列动态相关的亚型特异性模式
errmicroLife
IF0
err2026-01-01
err0
PREAI
errMitrofanov, Alexander; Beisel, Chase L.; Baumdicker, Franz; Alkhnbashi, Omer S.; Backofen, Rolf
err分享
err收藏
An updated evolutionary classification of CRISPR–Cas systems including rare variants包含稀有变体的CRISPR–Cas系统更新后的进化分类
errNature Microbiology
IF19.4
err2025-11-06
err0
errOAAI
errKira S. Makarova; Sergey A. Shmakov; Yuri I. Wolf; Pascal Mutz; Han Altae-Tran; Chase L. Beisel; Stan J. J. Brouns; Emmanuelle Charpentier; David Cheng; Jennifer Doudna; Daniel H. Haft; Philippe Horvath; Sylvain Moineau; Francisco J. M. Mojica; Patrick Pausch; Rafael Pinilla-Redondo; Shiraz A. Shah; Virginijus Siksnys; Michael P. Terns; Jesse Tordoff; Česlovas Venclovas; Malcolm F. White; Alexander F. Yakunin; Feng Zhang; Roger A. Garrett; Rolf Backofen; John van der Oost; Rodolphe Barrangou; Eugene V. Koonin
err分享
err收藏
PAM-interacting domain turn-helix 51 motifs can improve Cas9-SpRY activityPAM-interacting domain turn-helix 51 motifs可以增强Cas9-SpRY活性
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-08-28
err0
PREAI
errEggenschwiler, Reto; Hoffmann, Thomas; Dmytrenko, Oleg; Opitz, Mika; Ackel-Zakour, Marlene; Wang, Pascal; McCallan, Shannon A.; Fraguas-Eggenschwiler, Mariane; Niemann, Heiner; Patronov, Atanas; Beisel, Chase L.; Cantz, Tobias
err分享
err收藏
Efficient encapsulation of CRISPR-Cas9 RNP in bioreducible nanogels and release in a cytosol-mimicking environment在生物可还原纳米凝胶中高效包封CRISPR-Cas9 RNP及其在细胞质模拟环境中的释放
errDiscover Nano
IF4.5
err2025-07-26
err0
errOAAI
errPeter Westarp; Thorsten Keller; Jessica Brand; Sonja Horvat; Krystyna Albrecht; Chase Beisel; Juergen Groll
err分享
err收藏
AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attackAcrVIB1通过促进易受RNase攻击的非功能性crRNA结合，抑制CRISPR-Cas13b免疫。
errMOLECULAR CELL
IF16.6
err2025-02-01
err1
errOAAI
errWandera, Katharina G.; Schmelz, Stefan; Migur, Angela; Kibe, Anuja; Lukat, Peer; Achmedov, Tatjana; Caliskan, Neva; Blankenfeldt, Wulf; Beisel, Chase L.
err分享
err收藏
A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection
errNATURE BIOTECHNOLOGY
IF41.7
err2024-10-31
err0
PREAI
errJabalera, Ylenia; Tascon, Igor; Samperio, Sara; Lopez-Alonso, Jorge P.; Gonzalez-Lopez, Monika; Aransay, Ana M.; Abascal-Palacios, Guillermo; Beisel, Chase L.; Ubarretxena-Belandia, Iban; Perez-Jimenez, Raul
err分享
err收藏
Phages to the rescue: in situ editing of the gut microbiota
errTRENDS IN MICROBIOLOGY
IF14.9
err2024-10-01
err0
errOAAI
errKamm, Charlotte; Beisel, Chase L.
err分享
err收藏
Ten Years of the Synthetic Biology Summer Course at Cold Spring Harbor Laboratory
errACS SYNTHETIC BIOLOGY
IF3.9
err2024-09-20
err0
errOAAI
errHaynes, Karmella A.; Andrews, Lauren B.; Beisel, Chase L.; Chappell, James; Samaniego, Christian E. Cuba; Dueber, John E.; Dunlop, Mary J.; Franco, Elisa; Lucks, Julius B.; Noireaux, Vincent; Savage, David F.; Silver, Pamela A.; Smanski, Michael; Young, Eric
err分享
err收藏
MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in the Drosophila gut during inflammation
errPLOS PATHOGENS
IF4.9
err2024-08-19
err3
errOAAI
errArias-Rojas, Aranzazu; Arifah, Adini Q.; Angelidou, Georgia; Alshaar, Belal; Schombel, Ursula; Forest, Emma; Frahm, Dagmar; Brinkmann, Volker; Paczia, Nicole; Beisel, Chase L.; Gisch, Nicolas; Iatsenko, Igor
err分享
err收藏
Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-08-17
err0
errOAAI
errKhakimzhan, Aset; Izri, Ziane; Thompson, Seth; Dmytrenko, Oleg; Fischer, Patrick; Beisel, Chase; Noireaux, Vincent
err分享
err收藏
TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases
errNATURE COMMUNICATIONS
IF15.7
err2024-07-13
err3
errOAAI
errJiao, Chunlei; Peeck, Natalia L.; Yu, Jiaqi; Ghaem Maghami, Mohammad; Kono, Sarah; Collias, Daphne; Martinez Diaz, Sandra L.; Larose, Rachael; Beisel, Chase L.
err分享
err收藏
A cell-free transcription-translation pipeline for recreating methylation patterns boosts DNA transformation in bacteria
errMOLECULAR CELL
IF16.6
err2024-07-01
err2
errOAAI
errVento, Justin M.; Durmusoglu, Deniz; Li, Tianyu; Patinios, Constantinos; Sullivan, Sean; Ttofali, Fani; van Schaik, John; Yu, Yanying; Wang, Yanyan; Barquist, Lars; Crook, Nathan; Beisel, Chase L.
err分享
err收藏
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-04-25
err4
errOAAI
errVialetto, Elena; Miele, Solange; Goren, Moran G.; Yu, Jiaqi; Yu, Yanying; Collias, Daphne; Beamud, Beatriz; Osbelt, Lisa; Lourenco, Marta; Strowig, Till; Brisse, Sylvain; Barquist, Lars; Qimron, Udi; Bikard, David; Beisel, Chase L.
err分享
err收藏
Expanding the flexibility of base editing for high-throughput genetic screens in bacteria
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-03-18
err3
errOAAI
errGawlitt, Sandra; Collins, Scott P.; Yu, Yanying; Blackman, Samuel A.; Barquist, Lars; Beisel, Chase L.
err分享
err收藏
A Hitchhiker's guide to CRISPR editing tools in bacteria
errEMBO REPORTS
IF6.2
err2024-02-12
err5
errOAAI
errKrink, Nicolas; Nikel, Pablo Ivan; Beisel, Chase L.
err分享
err收藏
CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron基于CRISPR筛选拟杆菌的胆汁易感性小RNA调节剂
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-01-31
err3
errOAAI
errPrezza, Gianluca; Liao, Chunyu; Reichardt, Sarah; Beisel, Chase L.; Westermann, Alexander J.
err分享
err收藏
Improved prediction of bacterial CRISPRi guide efficiency from depletion screens through mixed-effect machine learning and data integration
errGENOME BIOLOGY
IF9.4
err2024-01-11
err9
errOAAI
errYu, Yanying; Gawlitt, Sandra; Barros E Sousa, Lisa; Merdivan, Erinc; Piraud, Marie; Beisel, Chase L.; Barquist, Lars
err分享
err收藏

研究方向

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合作学者
合作期刊
J
Jennifer A. Doudna
H 指数: 149 · 论文数: 674
Y
Yuri I. Wolf
H 指数: 121 · 论文数: 518
顾
顾臻 (Zhen Gu)
H 指数: 120 · 论文数: 517
P
Pamela A. Silver
H 指数: 116 · 论文数: 525
赵宏宇 封面图
赵宏宇 (Hongyu Zhao)
H 指数: 115 · 论文数: 1.4K
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