Tune H. Pers - Publications, H-index & Citations

Tune H. Pers

university of copenhagen

81H指数

262论文数

5.1W被引数

收录论文 92

发表时间

Cagrilintide and retatrutide combination therapy enhances weight loss and metabolic outcomes in obese male rats 卡格列汀和雷肽鲁肽联合疗法增强肥胖雄性大鼠的体重减轻和代谢结局

Nature Metabolism

IF20.8

2026-09-15

PREAI

Jonas Petersen; Christoffer Merrild; Stephanie Kjærulff Holm; Nigel Kurgan; Shad Hassan; Cecilie Vad Mathiesen; Stina Börchers; Charlotte Svendsen; Sergio D’Anna; Nicoline R. Andersen; Anders Bue Klein; Andreas M. Fritzen; Atul S. Deshmukh; Tune H. Pers; Christoffer Clemmensen

Single-cell profiling identifies obesity-disrupted brain glucose sensing 单细胞分析鉴定了肥胖破坏的脑葡萄糖传感

Nature Communications

IF15.7

2026-08-31

OAAI

Jenny M. Brown; Marie A. Bentsen; Anja Moltke Jørgensen; Thomas Svava Nielsen; Dylan M. Belmont-Rausch; Din Selmanovic; Oksana Dmytriyeva; Charlotte Høy Kruse; Nadia N. Aalling; Dana C. Schwalbe; Oliver Knights Møller; John N. Campbell; Anna Secher; Michael W. Schwartz; Tune H. Pers

Semaglutide attenuates neuroinflammation in male mice 司美格鲁肽减轻雄性小鼠的神经炎症

Nature Communications

IF15.7

2026-06-09

OAAI

Dylan M. Belmont-Rausch; Mette Q. Ludwig; Marie A. Bentsen; Stine N. Hansen; Anna Secher; Dorte Holst; Jaime Moreno; Vivek Das; Kristoffer L. Egerod; Anne-Mette Bjerregaard; Kristoffer Niss; Sarah Bau; Charles Pyke; Kevin Dalgaard; Myrte Merkestein; Franziska Wichern; Charlotte Thim Hansen; Joseph Polex-Wolf; Lotte Bjerre Knudsen; Tune H. Pers

A cross-species atlas of the dorsal vagal complex reveals neural mediators of the effects of cagrilintide on energy balance 跨物种背侧迷走神经复合体图谱揭示了卡格里林肽对能量平衡效应的神经中介

Nature Metabolism

IF20.8

2026-06-08

OAAI

Mette Q. Ludwig; Bernd Coester; Desiree Gordian; Shad Hassan; Abigail J. Tomlinson; Mouhamadoul Habib Toure; Oliver P. Christensen; Greta Lommi; Anja Moltke-Prehn; Jenny M. Brown; Dylan M. Belmont-Rausch; Sarah Bau; Cagri Bodur; Anika Gowda; Iris Wu; Stace Kernodle; Victoria Dong; Mike Ayensu-Mensah; Paul V. Sabatini; Jae Hoon Shin; Melissa Kirigiti; Kristoffer L. Egerod; Christelle Le Foll; Sofia Lundh; Marina Kjærgaard Gerstenberg; Thomas A. Lutz; Paul Kievit; Anna Secher; Kirsten Raun; Martin G. Myers; Tune H. Pers

Heterogeneity of the intestinal mononuclear phagocyte compartment in health and inflammatory bowel disease 肠道单核吞噬细胞系统在健康与炎症性肠病中的异质性

Science Immunology

IF16.3

2025-12-12

PREAI

Thomas M. Fenton; Line Wulff; Venla Väänänen; Gareth-Rhys Jones; Camilla Koldbæk Lemvigh; Lene B. Riis; Mads Damsgaard Wewer; Julien Vandamme; Peter B. Jørgensen; Calum C. Bain; Kirstine G. Belling; Gwo-Tzer Ho; Tune H. Pers; Anja Poulsen; Gorm R. Madsen; Ole H. Nielsen; Henrik L. Jakobsen; Jose MG. Izarzugaza; Flemming Bendtsen; Søren Brunak; Allan M. Mowat; Lars R. Olsen; Urs Mörbe; William W. Agace

Sustained diabetes remission induced by FGF1 involves a shift in transcriptionally distinct AgRP neuron subpopulations FGF1诱导的持续性糖尿病缓解涉及转录差异的AgRP神经元亚群的变化

Molecular Metabolism

IF6.6

2025-12-09

OAAI

Nadia Aalling; Petar V. Todorov; Shad Hassan; Dylan M. Belmont-Rausch; Oliver Pugerup Christensen; Claes Ottzen Laurentiussen; Anja M. Jørgensen; Kimberly M. Alonge; Jarrad M. Scarlett; Zaman Mirzadeh; Jenny M. Brown; Michael W. Schwartz; Tune H. Pers

The NMDA Receptor Antagonist Memantine Modulates Aging and Stress Resilience NMDA受体拮抗剂美金刚调节衰老和压力恢复力

AGING CELL

IF7.1

2025-11-01

OAAI

Juozaityte, Vaida; Pregnolato, Chiara; Abay-norgaard, Steffen; Rausch, Dylan Matthew; Mcintyre, Rebecca L.; Gerhart-hines, Zachary; Pers, Tune H.; Salcini, Anna Elisabetta; Clemmensen, Christoffer

Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism 人体肠道内常见细菌合成的多肽改善了啮齿类动物的代谢

Nature Microbiology

IF19.4

2025-07-31

OAAI

Yong Fan; Liwei Lyu; Ruben Vazquez-Uribe; Wanliang Zhang; Mareike Bongers; Andreas Koulouktsis; Mengliu Yang; Vita Sereika-Bejder; Tulika Arora; Evelina Stankevic; Jeremy Armetta; Franziska Zosel; Charlotta D. de la Cour; Lotte Simonsen; Alina Kulakova; Michael Wierer; Pernille Harris; Joachim Gæde; Peter Rossing; Filip K. Knop; Tune H. Pers; Tue Haldor Hansen; Trine Nielsen; Ling Li; Kristian Strømgaard; Gangyi Yang; Morten Otto Alexander Sommer; Oluf Pedersen

Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3 Cagrilintide通过大脑amylin受体1和3降低体重

eBioMedicine

IF10.8

2025-07-03

PREAI

Alexandra Oliveira Carvas; Andrea Leuthardt; Patricia Kulka; Greta Lommi; Shad Hassan; Bernd Coester; Sofia Lundh; Tune Pers; Anna Secher; Kirsten Raun; Thomas A. Lutz; Christelle Le Foll

Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety

NATURE METABOLISM

IF20.8

2024-12-03

PREAI

Webster, Addison N.; Becker, Jordan J.; Li, Chia; Schwalbe, Dana C.; Kerspern, Damien; Karolczak, Eva O.; Bundon, Catherine B.; Onoharigho, Roberta A.; Crook, Maisie; Jalil, Maira; Godschall, Elizabeth N.; Dame, Emily G.; Dawer, Adam; Belmont-Rausch, Dylan Matthew; Pers, Tune H.; Lutas, Andrew; Habib, Naomi; Gueler, Ali D.; Krashes, Michael J.; Campbell, John N.

Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R 防止过度喂养引起的体重增加在肥胖中得到保护，但不需要FGF21或MC4R

NATURE COMMUNICATIONS

IF15.7

2024-02-08

OAAI

Lund, Camilla; Ranea-Robles, Pablo; Falk, Sarah; Rausch, Dylan M.; Skovbjerg, Grethe; Vibe-Petersen, Victoria Kamma; Krauth, Nathalie; Skytte, Jacob Lercke; Vana, Vasiliki; Roostalu, Urmas; Pers, Tune H.; Lund, Jens; Clemmensen, Christoffer

Assessing household lifestyle exposures from consumer purchases, the My Purchases cohort

SCIENTIFIC REPORTS

IF3.9

2023-12-07

OAAI

Moller, Frederik T.; Junker, Thor Gronborg; Sorensen, Kathrine Kold; Eves, Caroline; Wohlfahrt, Jan; Dillner, Joakim; Torp-Pedersen, Christian; Wilkowski, Bartlomiej; Chong, Steven; Pers, Tune H.; Yakimov, Victor; Mueller, Heimo; Ethelberg, Steen; Melbye, Mads

GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification 476,326个体中随机葡萄糖的gis提供了对糖尿病病理生理学，并发症和治疗分层的见解

NATURE GENETICS

IF31.8

2023-09-07

OAAI

Lagou, Vasiliki; Jiang, Longda; Ulrich, Anna; Zudina, Liudmila; Gonzalez, Karla Sofia Gutierrez; Balkhiyarova, Zhanna; Faggian, Alessia; Maina, Jared G.; Chen, Shiqian; Todorov, Petar V.; Sharapov, Sodbo; David, Alessia; Marullo, Letizia; Magi, Reedik; Rujan, Roxana-Maria; Ahlqvist, Emma; Thorleifsson, Gudmar; Gao, He; Evangelou, Evangelos; Benyamin, Beben; Scott, Robert A.; Isaacs, Aaron; Zhao, Jing Hua; Willems, Sara M.; Johnson, Toby; Gieger, Christian; Grallert, Harald; Meisinger, Christa; Mueller-Nurasyid, Martina; Strawbridge, Rona J.; Goel, Anuj; Rybin, Denis; Albrecht, Eva; Jackson, Anne U.; Stringham, Heather M.; Correa, Ivan R., Jr.; Farber-Eger, Eric; Steinthorsdottir, Valgerdur; Uitterlinden, Andre G.; Munroe, Patricia B.; Brown, Morris J.; Schmidberger, Julian; Holmen, Oddgeir; Thorand, Barbara; Hveem, Kristian; Wilsgaard, Tom; Mohlke, Karen L.; Wang, Zhe; Shmeliov, Aleksey; den Hoed, Marcel; Loos, Ruth J. F.; Kratzer, Wolfgang; Haenle, Mark; Koenig, Wolfgang; Boehm, Bernhard O.; Tan, Tricia M.; Tomas, Alejandra; Salem, Victoria; Barroso, Ines; Tuomilehto, Jaakko; Boehnke, Michael; Florez, Jose C.; Hamsten, Anders; Watkins, Hugh; Njolstad, Inger; Wichmann, H. -Erich; Caulfield, Mark J.; Khaw, Kay-Tee; van Duijn, Cornelia M.; Hofman, Albert; Wareham, Nicholas J.; Langenberg, Claudia; Whitfield, John B.; Martin, Nicholas G.; Montgomery, Grant; Scapoli, Chiara; Tzoulaki, Ioanna; Elliott, Paul; Thorsteinsdottir, Unnur; Stefansson, Kari; Brittain, Evan L.; McCarthy, Mark I.; Froguel, Philippe; Sexton, Patrick M.; Wootten, Denise; Groop, Leif; Dupuis, Josee; Meigs, James B.; Deganutti, Giuseppe; Demirkan, Ayse; Pers, Tune H.; Reynolds, Christopher A.; Aulchenko, Yurii S.; Kaakinen, Marika A.; Jones, Ben; Prokopenko, Inga

Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots 成脂细胞和SWAT细胞与人类棕色和白色脂肪库中的共同祖细胞分开

NATURE METABOLISM

IF20.8

2023-06-19

OAAI

Palani, Nagendra P.; Horvath, Carla; Timshel, Pascal N.; Folkertsma, Pytrik; Gronning, Alexander G. B.; Henriksen, Tora I.; Peijs, Lone; Jensen, Verena H.; Sun, Wenfei; Jespersen, Naja Z.; Wolfrum, Christian; Pers, Tune H.; Nielsen, Soren; Scheele, Camilla

GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity GLP-1和尼古丁联合治疗可通过下丘脑和中脑边缘途径逆转肥胖

CELL REPORTS

IF6.9

2023-05-01

OAAI

Falk, Sarah; Petersen, Jonas; Svendsen, Charlotte; Romero-Leguizamon, Cesar R.; Jorgensen, Soren Heide; Krauth, Nathalie; Ludwig, Mette Q.; Lundo, Kathrine; Roostalu, Urmas; Skovbjerg, Grethe; Nielsen, Duy Anh Gurskov; Ejdrup, Aske Lykke; Pers, Tune H.; Dmytriyeva, Oksana; Hecksher-Sorensen, Jacob; Gether, Ulrik; Kohlmeier, Kristi A.; Clemmensen, Christoffer

A Lipopolysaccharide Mouse Model Mirrors Neuroinflammatory Transcriptional Signatures of Human AD, and the Glucagon-Like Peptide-1 Receptor Agonist Semaglutide Attenuates Neuroinflammation in this Model

NEUROLOGY

IF8.5

2023-04-25

PREAI

Ludwig, Mette Q.; Belmont-Rausch, Dylan M.; Secher, Anna; Bentsen, Marie A.; Hansen, Stine Normann; Bjerregaard, Anne-Mette; Niss, Kristoffer; Egerod, Kristoffer L.; Hansen, Charlotte T.; Dalgaard, Kevin D.; Merkestein, Myrte; Holst, Dorte; Pyke, Charles; Wichern, Franziska; Polex-Wolf, Joseph; Pers, Tune H.; Knudsen, Lotte B.

A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development

SCIENCE ADVANCES

IF12.5

2023-04-07

OAAI

Lee, Julie; Moller, Andreas Fonss; Chae, Shinhyeok; Bussek, Alexandra; Park, Tae Joo; Kim, Youni; Lee, Hyun-Shik; Pers, Tune H.; Kwon, Taejoon; Sedzinski, Jakub; Natarajan, Kedar Nath

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention 身体活动和久坐行为的全基因组关联分析提供了对疾病预防的潜在机制和作用的见解

NATURE GENETICS

IF31.8

2022-09-07

OAAI

Wang, Zhe; Emmerich, Andrew; Pillon, Nicolas J.; Moore, Tim; Hemerich, Daiane; Cornelis, Marilyn C.; Mazzaferro, Eugenia; Broos, Siacia; Ahluwalia, Tarunveer S.; Bartz, Traci M.; Bentley, Amy R.; Bielak, Lawrence F.; Chong, Mike; Chu, Audrey Y.; Berry, Diane; Dorajoo, Rajkumar; Dueker, Nicole D.; Kasbohm, Elisa; Feenstra, Bjarke; Feitosa, Mary F.; Gieger, Christian; Graff, Mariaelisa; Hall, Leanne M.; Haller, Toomas; Hartwig, Fernando P.; Hillis, David A.; Huikari, Ville; Heard-Costa, Nancy; Holzapfel, Christina; Jackson, Anne U.; Johansson, Asa; Jorgensen, Anja Moltke; Kaakinen, Marika A.; Karlsson, Robert; Kerr, Kathleen F.; Kim, Boram; Koolhaas, Chantal M.; Kutalik, Zoltan; Lagou, Vasiliki; Lind, Penelope A.; Lorentzon, Mattias; Lyytikainen, Leo-Pekka; Mangino, Massimo; Metzendorf, Christoph; Monroe, Kristine R.; Pacolet, Alexander; Perusse, Louis; Pool, Rene; Richmond, Rebecca C.; Rivera, Natalia, V; Robiou-Du-Pont, Sebastien; Schraut, Katharina E.; Schulz, Christina-Alexandra; Stringham, Heather M.; Tanaka, Toshiko; Teumer, Alexander; Turman, Constance; Van der Most, Peter J.; Vanmunster, Mathias; Van Rooij, Frank J. A.; Van Vliet-Ostaptchouk, Jana V.; Zhang, Xiaoshuai; Zhao, Jing-Hua; Zhao, Wei; Balkhiyarova, Zhanna; Balslev-Harder, Marie N.; Baumeister, Sebastian E.; Beilby, John; Blangero, John; Boomsma, Dorret, I; Brage, Soren; Braund, Peter S.; Brody, Jennifer A.; Bruinenberg, Marcel; Ekelund, Ulf; Liu, Ching-Ti; Cole, John W.; Collins, Francis S.; Cupples, L. Adrienne; Esko, Tonu; Enroth, Stefan; Faul, Jessica D.; Fernandez-Rhodes, Lindsay; Fohner, Alison E.; Franco, Oscar H.; Galesloot, Tessel E.; Gordon, Scott D.; Grarup, Niels; Hartman, Catharina A.; Heiss, Gerardo; Hui, Jennie; Illig, Thomas; Jago, Russell; James, Alan; Joshi, Peter K.; Jung, Taeyeong; Kahonen, Mika; Kilpelainen, Tuomas O.; Koh, Woon-Puay; Kolcic, Ivana; Kraft, Peter P.; Kuusisto, Johanna; Launer, Lenore J.; Li, Aihua; Linneberg, Allan; Luan, Jian'An; Vidal, Pedro Marques; Medland, Sarah E.; Milaneschi, Yuri; Moscati, Arden; Musk, Bill; Nelson, Christopher P.; Nolte, Ilja M.; Pedersen, Nancy L.; Peters, Annette; Peyser, Patricia A.; Power, Christine; Raitakari, Olli T.; Reedik, Magi; Reiner, Alex P.; Ridker, Paul M.; Rudan, Igor; Ryan, Kathy; Sarzynski, Mark A.; Scott, Laura J.; Scott, Robert A.; Sidney, Stephen; Siggeirsdottir, Kristin; Smith, Albert, V; Smith, Jennifer A.; Sonestedt, Emily; Strom, Marin; Tai, E. Shyong; Teo, Koon K.; Thorand, Barbara; Toenjes, Anke; Tremblay, Angelo; Uitterlinden, Andre G.; Vangipurapu, Jagadish; Van Schoor, Natasja; Volker, Uwe; Willemsen, Gonneke; Williams, Kayleen; Wong, Quenna; Xu, Huichun; Young, Kristin L.; Yuan, Jian Min; Zillikens, M. Carola; Zonderman, Alan B.; Ameur, Adam; Bandinelli, Stefania; Bis, Joshua C.; Boehnke, Michael; Bouchard, Claude; Chasman, Daniel, I; Smith, George Davey; De Geus, Eco J. C.; Deldicque, Louise; Dorr, Marcus; Evans, Michele K.; Ferrucci, Luigi; Fornage, Myriam; Fox, Caroline; Garland, Theodore, Jr.; Gudnason, Vilmundur; Gyllensten, Ulf; Hansen, Torben; Hayward, Caroline; Horta, Bernardo L.; Hypponen, Elina; Jarvelin, Marjo-Riitta; Johnson, W. Craig; Kardia, Sharon L. R.; Kiemeney, Lambertus A.; Laakso, Markku; Langenberg, Claudia; Lehtimaki, Terho; Le Marchand, Loic; Magnusson, Patrik K. E.; Martin, Nicholas G.; Melbye, Mads; Metspalu, Andres; Meyre, David; North, Kari E.; Ohlsson, Claes; Oldehinkel, Albertine J.; Orho-Melander, Marju; Pare, Guillaume; Park, Taesung; Pedersen, Oluf; Penninx, Brenda W. J. H.; Pers, Tune H.; Polasek, Ozren; Prokopenko, Inga; Rotimi, Charles N.; Samani, Nilesh J.; Sim, Xueling; Snieder, Harold; Sorensen, Thorkild I. A.; Spector, Tim D.; Timpson, Nicholas J.; Van Dam, Rob M.; Van der Velde, Nathalie; Van Duijn, Cornelia M.; Vollenweider, Peter; Volzke, Henry; Voortman, Trudy; Waeber, Gerard; Wareham, Nicholas J.; Weir, David R.; Wichmann, Heinz-Erich; Wilson, James F.; Hevener, Andrea L.; Krook, Anna; Zierath, Juleen R.; Thomis, Martine A., I; Loos, Ruth J. F.; Den Hoed, Marcel

Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis 人非酒精性脂肪性肝炎的单细胞转录组和细胞类型特异性分子途径

SCIENTIFIC REPORTS

IF3.9

2022-08-05

OAAI

Fred, Rikard G.; Pedersen, Julie Steen; Thompson, Jonatan J.; Lee, Julie; Timshel, Pascal N.; Stender, Stefan; Rygg, Marte Opseth; Gluud, Lise Lotte; Kristiansen, Viggo Bjerregaard; Bendtsen, Flemming; Hansen, Torben; Pers, Tune H.

Hindbrain circuits in the control of eating behaviour and energy balance 控制饮食行为和能量平衡的后脑回路

NATURE METABOLISM

IF20.8

2022-07-25

PREAI

Cheng, Wenwen; Gordian, Desiree; Ludwig, Mette Q.; Pers, Tune H.; Seeley, Randy J.; Myers, Martin G., Jr.

研究方向