Daniel Bedinger - Publications, H-index & Citations

Daniel Bedinger

carterra

18H指数

40论文数

1.4K被引数

收录论文 19

发表时间

A blinded, prospective benchmark of in silico antibody discovery anchored to experimental affinity and developability 一项基于实验亲和力与可开发性的模拟抗体发现的盲法前瞻性基准研究

Nature Biotechnology

IF41.7

2026-08-19

OAAI

M. Frank Erasmus; Daniel Bedinger; Elizabeth Hopkins; Ginger Ferguson; Justine Strickler; Christilyn P. Graff; Samantha R. Summers; Stacy L. Capehart; Joshua D. Slocum; Crystal Richardson; Sumit Kumar; Zhifei Sun; Yujie Shang; Jixian Zhang; Ming Gu; Lixia Yi; Alon Wellner; Shuangjia Zheng; Wei Lu; Pietro Sormanni; Matthew Greenig; Haiping Zhang; Brendan T. Mann; Mahdi Baghbanzadeh; Ali Rahnavard; Gregory L. Moore; Huaiyu Sun; Ying Ding; Alex Nisthal; Jitendra Kanodia; Matthew J. Bernett; Aurélien Pélissier; Yanjun Shao; Maria Rodriguez Martinez; Karthik Ramesh; Horacio Nastri; Andreas Evers; Anhar Abdelatif; Andrew J. Bordner; Mykola Bordyuh; Lim Heo; Brian A. Kidd; H. Serhat Tetikol; Shuai Wei; Jung-Eun Shin; Ryan Peckner; Leigh Manley; Ajitesh Lunge; Yashas Devasurmutt; Bora Guloglu; Liviu Copoiu; Miles McGibbon; Monica L. Fernandez-Quintero; Nitesh Mishra; Sean M. Callaghan; Olivia M. Swanson; Daniel L. V. Bader; James A. Ferguson; Sai S. R. Raghavan; Benjamin Nemoz; Colleen A. Maillie; Charles Bowman; Bryan Briney; Andrew B. Ward; Paolo Marcatili; Rahmad Akbar; Bing He; Fandi Wu; Jianhua Yao; Bin Hu; Michal Kucer; Kaetlyn Rose Gibson; Rahul Somasundaram; Li-Wei Hung; Tomasz Kaszuba; Daved H. Fremont; Hyeongsun Jeong; Vinodh Babu Kurella; Shipra Malhotra; Satyendra Kumar; Yanyun Liu; Lingling Xu; Joshua Misa; Alexander Nicholas St. John; Jeff Vogt; Fátima A. Dávila-Hernández; Da Xu; Michael Chungyoun; Zyaja D. Huggan; Jeffrey J. Gray; Jonathan Parkinson; Young Su Ko; Wei Wang; Franziska Geiger; Jonathon D. Ziegler; Nikhil Haas; Chance Challacombe; Ahmad Qamar; Akshita Singh; Yi-Ching Tang; Zhiqiang An; Xiaoqian Jiang; Yejin Kim; Xinyan Zhao; Erik Swanson; Jürgen Klattig; Karsten Winkler; Tschimegma Bataa; Volker Sandig; Lilian Denzler; Chunan Liu; Randall J. Brezski; Laura Spector; Katheryn Perea-Schmittle; Sara D’Angelo; Fortunato Ferrara; Andrew R. M. Bradbury

SARS-CoV-2 antibody-dependent enhancement of infection depends on antibody binding to both ACE2 and Fc receptors SARS-CoV-2抗体依赖性增强感染取决于抗体同时结合ACE2和Fc受体

JCI Insight

IF6.1

2026-02-23

OAAI

Kuzmina, Natalia A.; Periasamy, Sivakumar; Kedarinath, Kritika; Hernandez, Keziah; Atyeo, Caroline; Dennison, S. Moses; Li, Kan; Bedinger, Daniel; Schendel, Sharon L.; Tomaras, Georgia D.; Ali, Hanif; Alter, Galit; Saphire, Erica Ollmann; Bukreyev, Alexander

A global collaboration for systematic analysis of broad-ranging antibodies against the SARS-CoV-2 spike protein 一项全球合作，用于对针对SARS-CoV-2刺突蛋白的广谱抗体的系统分析

CELL REPORTS

IF6.9

2025-04-01

OAAI

Schendel, Sharon L.; Yu, Xiaoying; Halfmann, Peter J.; Mahita, Jarjapu; Ha, Brendan; Hastie, Kathryn M.; Li, Haoyang; Bedinger, Daniel; Troup, Camille; Li, Kan; Kuzmina, Natalia; Torrelles, Jordi B.; Munt, Jennifer E.; Maddocks, Melissa; Osei-Twum, Mary; Callaway, Heather M.; Reece, Stephen; Palser, Anne; Kellam, Paul; Dennison, S. Moses; Huntwork, Richard H. C.; Horn, Gillian Q.; Abraha, Milite; Feeney, Elizabeth; Martinez-Sobrido, Luis; Pino, Paula A.; Hicks, Amberlee; Ye, Chengjin; Park, Jun-Gyu; Maingot, Billie; Periasamy, Sivakumar; Mallory, Michael; Scobey, Trevor; Lepage, Marie-Noelle; St-Amant, Natalie; Khan, Sarwat; Gambiez, Anais; Baric, Ralph S.; Bukreyev, Alexander; Gagnon, Luc; Germann, Timothy; Kawaoka, Yoshihiro; Tomaras, Georgia D.; Peters, Bjoern; Saphire, Erica Ollmann

AIntibody: an experimentally validated in silico antibody discovery design challenge

NATURE BIOTECHNOLOGY

IF41.7

2024-11-04

OAAI

Erasmus, M. Frank; Spector, Laura; Ferrara, Fortunato; Diniro, Roberto; Pohl, Thomas J.; Perea-Schmittle, Katheryn; Wang, Wei; Tessier, Peter M.; Richardson, Crystal; Turner, Laure; Kumar, Sumit; Bedinger, Daniel; Sormanni, Pietro; Fernandez-Quintero, Monica L.; Ward, Andrew B.; Loeffler, Johannes R.; Swanson, Olivia M.; Deane, Charlotte M.; Raybould, Matthew I. J.; Evers, Andreas; Sellmann, Carolin; Bachas, Sharrol; Ruffolo, Jeff; Nastri, Horacio G.; Ramesh, Karthik; Sorensen, Jesper; Croasdale-Wood, Rebecca; Hijano, Oliver; Leal-Lopes, Camila; Shahsavarian, Melody; Qiu, Yu; Marcatili, Paolo; Vernet, Erik; Akbar, Rahmad; Friedensohn, Simon; Wagner, Rick; Kurella, Vinodh babu; Malhotra, Shipra; Kumar, Satyendra; Kidger, Patrick; Almagro, Juan C.; Furfine, Eric; Stanton, Marty; Graff, Christilyn P.; Villalba, Santiago David; Tomszak, Florian; Teixeira, Andre A. R.; Hopkins, Elizabeth; Dovner, Molly; D'Angelo, Sara; Bradbury, Andrew R. M.

Widespread monoclonal IgE antibody convergence to an immunodominant, proanaphylactic Ara h 2 epitope in peanut allergy

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IF11.2

2024-01-01

OAAI

Croote, Derek; Wong, Joyce J. W.; Pecalvel, Cyprien; Leveque, Edouard; Casanovas, Natacha; Kamphuis, Jasper B. J.; Creeks, Paige; Romero, Johanna; Sohail, Saba; Bedinger, Daniel; Nadeau, Kari C.; Chinthrajah, Rebecca S.; Reber, Laurent L.; Lowman, Henry B.

Cryptic-site-specific antibodies to the SARS-CoV-2 receptor binding domain can retain functional binding affinity to spike variants

JOURNAL OF VIROLOGY

IF3.8

2023-12-21

OAAI

Li, Kan; Huntwork, Richard H. C.; Horn, Gillian Q.; Abraha, Milite; Hastie, Kathryn M.; Li, Haoyang; Rayaprolu, Vamseedhar; Olmedillas, Eduardo; Feeney, Elizabeth; Cronin, Kenneth; Schendel, Sharon L.; Heise, Mark; Bedinger, Daniel; Mattocks, Melissa D.; Baric, Ralph S.; Alam, S. Munir; Ollmann Saphire, Erica; Tomaras, Georgia D.; Dennison, S. Moses

Coronavirus Immunotherapeutic Consortium Database

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION

IF3.6

2023-02-10

OAAI

Mahita, Jarjapu; Ha, Brendan; Gambiez, Anais; Schendel, Sharon L.; Li, Haoyang; Hastie, Kathryn M.; Dennison, S. Moses; Li, Kan; Kuzmina, Natalia; Periasamy, Sivakumar; Bukreyev, Alexander; Munt, Jennifer E.; Osei-Twum, Mary; Atyeo, Caroline; Overton, James A.; Vita, Randi; Guzman-Orozco, Hector; Mendes, Marcus; Kojima, Mari; Halfmann, Peter J.; Kawaoka, Yoshihiro; Alter, Galit; Gagnon, Luc; Baric, Ralph S.; Tomaras, Georgia D.; Germann, Tim; Bedinger, Daniel; Greenbaum, Jason A.; Saphire, Erica Ollmann; Peters, Bjoern

Healthy humans can be a source of antibodies countering COVID-19

BIOENGINEERED

IF4.2

2022-05-21

OAAI

Velappan, Nileena; Nguyen, Hau B.; Micheva-Viteva, Sofiya; Bedinger, Daniel; Ye, Chunyan; Mangadu, Betty; Watts, Austin J.; Meagher, Robert; Bradfute, Steven; Hu, Bin; Waldo, Geoffrey S.; Lillo, Antonietta M.

A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library

MABS

IF7.3

2018-02-01

OAAI

Adler, Adam S.; Bedinger, Daniel; Adams, Matthew S.; Asensio, Michael A.; Edgar, Robert C.; Leong, Renee; Leong, Jackson; Mizrahi, Rena A.; Spindler, Matthew J.; Bandi, Srinivasa Rao; Huang, Haichun; Tawde, Pallavi; Brams, Peter; Johnson, David S.

Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets

MABS

IF7.3

2017-11-02

OAAI

Ching, Kathryn H.; Collarini, Ellen J.; Abdiche, Yasmina N.; Bedinger, Daniel; Pedersen, Darlene; Izquierdo, Shelley; Harriman, Rian; Zhu, Lei; Etches, Robert J.; van de Lavoir, Marie-Cecile; Harriman, William D.; Leighton, Philip A.

Impacting Humoral Hypercalcemia of Malignancy (HHM) and associated PTH1R-mediated morbidities: Characterization of an anti-PTH1R antagonist monoclonal antibody to reverse hypercalcemia

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Mirza, Amer M.; Choppin, Agnes; Bedinger, Daniel; Hunt, Rachel; Cotter, Robyn; Pongo, Elizabeth; Ahluwalia, Kiran; Tran, Catarina; Lao, Llewelyn; Lind, Kristin; Wijesuriya, Sujeewa; Webster, Lynn; Zhang, Fangjiu; Johnson, Kirk; Takeuchi, Toshihiko; Levy, Raphael

Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms

MABS

IF7.3

2015-11-13

OAAI

Bedinger, Daniel; Lao, Llewelyn; Khan, Shireen; Lee, Steve; Takeuchi, Toshihiko; Mirza, Amer M.

Metabolic, anabolic, and mitogenic insulin responses: A tissue-specific perspective for insulin receptor activators

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2015-11-01

PREAI

Bedinger, Daniel H.; Adams, Sean H.

Acute Treatment With XMetA Activates Hepatic Insulin Receptors and Lowers Blood Glucose in Normal Mice

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2015-07-23

PREAI

Bedinger, Daniel H.; Kieffer, Dorothy A.; Goldfine, Ira D.; Roell, Marina K.; Adams, Sean H.

Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2015-04-01

OAAI

Bedinger, Daniel H.; Goldfine, Ira D.; Corbin, John A.; Roell, Marina K.; Adams, Sean H.

Discovery and characterization of fully human monoclonal antibodies that neutralize multiple TGFβ isoforms

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Mirza, Amer; Bedinger, Daniel; Lao, Llewelyn; Khan, Shireen; Takeuchi, Toshihiko

Inhibition of insulin receptor function by a human, allosteric monoclonal antibody A potential new approach for the treatment of hyperinsulinemic hypoglycemia

MABS

IF7.3

2013-10-28

OAAI

Corbin, John A.; Bhaskar, Vinay; Goldfine, Ira D.; Issafras, Hassan; Bedinger, Daniel H.; Lau, Angela; Michelson, Kristen; Gross, Lisa M.; Maddux, Betty A.; Kuan, Hua F.; Tran, Catarina; Lao, Llewelyn; Handa, Masahisa; Watson, Susan R.; Narasimha, Ajay J.; Zhu, Shirley; Levy, Raphael; Webster, Lynn; Wijesuriya, Sujeewa D.; Liu, Naichi; Wu, Xiaorong; Chemla-Vogel, David; Lee, Steve R.; Wong, Steve; Wilcock, Diane; Rubin, Paul; White, Mark L.

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control

DIABETES

IF7.5

2012-04-13

OAAI

Bhaskar, Vinay; Goldfine, Ira D.; Bedinger, Daniel H.; Lau, Angela; Kuan, Hua F.; Gross, Lisa M.; Handa, Masahisa; Maddux, Betty A.; Watson, Susan R.; Zhu, Shirley; Narasimha, Ajay J.; Levy, Raphael; Webster, Lynn; Wijesuriya, Sujeewa D.; Liu, Naichi; Wu, Xiaorong; Chemla-Vogel, David; Catarina Tran; Lee, Steve R.; Wong, Steve; Wilcock, Diane; White, Mark L.; Corbin, John A.

Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-07-01

OAAI

Roell, Marina K.; Issafras, Hassan; Bauer, Robert J.; Michelson, Kristen S.; Mendoza, Nerissa; Vanegas, Sandra I.; Gross, Lisa M.; Larsen, Paul D.; Bedinger, Daniel H.; Bohmann, David J.; Nonet, Genevieve H.; Liu, Naichi; Lee, Steve R.; Handa, Masahisa; Kantak, Seema S.; Horwitz, Arnold H.; Hunter, John J.; Owyang, Alexander M.; Mirza, Amer M.; Corbin, John A.; White, Mark L.

研究方向