未登录 A Sitewise Model of Natural Selection on Individual Antibodies via a Transformer-Encoder 通过Transformer-Encoder实现的针对单个抗体的位点模型自然选择 Matsen IV, Frederick A.; Sung, Kevin; Johnson, Mackenzie M.; Dumm, Will; Rich, David; Starr, Tyler N.; Song, Yun S.; Bradley, Philip; Fukuyama, Julia; Haddox, Hugh K. 分享 收藏
Delineating the functional activity of antibodies with cross-reactivity to SARS-CoV-2, SARS-CoV-1 and related sarbecoviruses Ruiz, Felicitas; Foreman, William B.; Lilly, Michelle; Baharani, Viren A.; Depierreux, Delphine M.; Chohan, Vrasha; Taylor, Ashley L.; Guenthoer, Jamie; Ralph, Duncan; Matsen, Frederick A.; Chu, Helen Y.; Bieniasz, Paul D.; Cote, Marceline; Starr, Tyler N.; Overbaugh, Julie 分享 收藏
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Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor 从接种BNT162b2的传染性非典型肺炎幸存者中分离出的有效泛huACE2-dependent肉瘤病毒中和单克隆抗体 Chia, Wan Ni; Tan, Chee Wah; Tan, Aaron Wai Kit; Young, Barnaby; Starr, Tyler N.; Lopez, Ester; Fibriansah, Guntur; Barr, Jennifer; Cheng, Samuel; Yeoh, Aileen Ying-Yan; Yap, Wee Chee; Lim, Beng Lee; Ng, Thiam-Seng; Sia, Wan Rong; Zhu, Feng; Chen, Shiwei; Zhang, Jinyan; Kwek, Madeline Sheng Si; Greaney, Allison J.; Chen, Mark; Au, Gough G.; Paradkar, Prasad N.; Peiris, Malik; Chung, Amy W.; Bloom, Jesse D.; Lye, David; Lok, Sheemei; Wang, Lin-Fa 分享 收藏
Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail Addetia, Amin; Park, Young -Jun; Starr, Tyler; Greaney, Allison J.; Sprouse, Kaitlin R.; Bowen, John E.; Tiles, Sasha W.; Voorhis, Wesley C. Van; Bloom, Jesse D.; Corti, Davide; Walls, Alexandra C.; Veesler, David 分享 收藏
Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection Guenthoer, Jamie; Lilly, Michelle; Starr, Tyler N.; Dadonaite, Bernadeta; Lovendahl, Klaus N.; Croft, Jacob T.; Stoddard, Caitlin I.; Chohan, Vrasha; Ding, Shilei; Ruiz, Felicitas; Kopp, Mackenzie S.; Bloom, Jesse D.; Chu, Helen Y.; Lee, Kelly K.; Overbaugh, Julie 分享 收藏
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Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1 Moulana, Alief; Dupic, Thomas; Phillips, Angela M.; Chang, Jeffrey; Nieves, Serafina; Roffler, Anne A.; Greaney, Allison J.; Starr, Tyler N.; Bloom, Jesse D.; Desai, Michael M. 分享 收藏
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice Hunt, Andrew C.; Case, James Brett; Park, Young-Jun; Cao, Longxing; Wu, Kejia; Walls, Alexandra C.; Liu, Zhuoming; Bowen, John E.; Yeh, Hsien-Wei; Saini, Shally; Helms, Louisa; Zhao, Yan Ting; Hsiang, Tien-Ying; Starr, Tyler N.; Goreshnik, Inna; Kozodoy, Lisa; Carter, Lauren; Ravichandran, Rashmi; Green, Lydia B.; Matochko, Wadim L.; Thomson, Christy A.; Vogeli, Bastian; Kruger, Antje; VanBlargan, Laura A.; Chen, Rita E.; Ying, Baoling; Bailey, Adam L.; Kafai, Natasha M.; Boyken, Scott E.; Ljubetic, Ajasja; Edman, Natasha; Ueda, George; Chow, Cameron M.; Johnson, Max; Addetia, Amin; Navarro, Mary-Jane; Panpradist, Nuttada; Gale, Michael, Jr.; Freedman, Benjamin S.; Bloom, Jesse D.; Ruohola-Baker, Hannele; Whelan, Sean P. J.; Stewart, Lance; Diamond, Michael S.; Veesler, David; Jewett, Michael C.; Baker, David 分享 收藏
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Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function 选择分析确定了Omicron谱系BA.1中可能影响尖峰功能的异常突变变化簇 Martin, Darren P.; Lytras, Spyros; Lucaci, Alexander G.; Maier, Wolfgang; Gruening, Bjoern; Shank, Stephen D.; Weaver, Steven; MacLean, Oscar A.; Orton, Richard J.; Lemey, Philippe; Boni, Maciej F.; Tegally, Houriiyah; Harkins, Gordon W.; Scheepers, Cathrine; Bhiman, Jinal N.; Everatt, Josie; Amoako, Daniel G.; San, James Emmanuel; Giandhari, Jennifer; Sigal, Alex; Williamson, Carolyn; Hsiao, Nei-yuan; von Gottberg, Anne; De Klerk, Arne; Shafer, Robert W.; Robertson, David L.; Wilkinson, Robert J.; Sewell, B. Trevor; Lessells, Richard; Nekrutenko, Anton; Greaney, Allison J.; Starr, Tyler N.; Bloom, Jesse D.; Murrell, Ben; Wilkinson, Eduan; Gupta, Ravindra K.; de Oliveira, Tulio; Kosakovsky Pond, Sergei L. 分享 收藏
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy Greaney, Allison; Starr, Tyler E.; Eguia, Rachel K.; Loes, Andrea; Khan, Khadija; Karim, Farina Y.; Cele, Sandile; Bowen, John D.; Logue, Jennifer L.; Corti, Davide; Veesler, David L.; Chu, Helen; Sigal, Alex L.; Bloom, Jesse 分享 收藏
Neutralizing Monoclonal Antibodies That Target the Spike Receptor Binding Domain Confer Fc Receptor-Independent Protection against SARS-CoV-2 Infection in Syrian Hamsters Su, Wen; Sia, Sin Fun; Schmitz, Aaron J.; Bricker, Traci L.; Starr, Tyler N.; Greaney, Allison J.; Turner, Jackson S.; Mohammed, Bassem M.; Liu, Zhuoming; Choy, Ka Tim; Darling, Tamarand L.; Joshi, Astha; Cheng, Ka Man; Wong, Alvina Y. L.; Harastani, Houda H.; Nicholls, John M.; Whelan, Sean P. J.; Bloom, Jesse D.; Yen, Hui-Ling; Ellebedy, Ali H.; Boon, Adrianus C. M. 分享 收藏
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies Greaney, Allison J.; Starr, Tyler N.; Barnes, Christopher O.; Weisblum, Yiska; Schmidt, Fabian; Caskey, Marina; Gaebler, Christian; Cho, Alice; Agudelo, Marianna; Finkin, Shlomo; Wang, Zijun; Poston, Daniel; Muecksch, Frauke; Hatziioannou, Theodora; Bieniasz, Paul D.; Robbiani, Davide F.; Nussenzweig, Michel C.; Bjorkman, Pamela J.; Bloom, Jesse D. 分享 收藏
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Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design Ellis, Daniel; Brunette, Natalie; Crawford, Katharine H. D.; Walls, Alexandra C.; Pham, Minh N.; Chen, Chengbo; Herpoldt, Karla-Luise; Fiala, Brooke; Murphy, Michael; Pettie, Deleah; Kraft, John C.; Malone, Keara D.; Navarro, Mary Jane; Ogohara, Cassandra; Kepl, Elizabeth; Ravichandran, Rashmi; Sydeman, Claire; Ahlrichs, Maggie; Johnson, Max; Blackstone, Alyssa; Carter, Lauren; Starr, Tyler N.; Greaney, Allison J.; Lee, Kelly K.; Veesler, David; Bloom, Jesse D.; King, Neil P. 分享 收藏
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