Kam Y. J. Zhang - Publications, H-index & Citations

Kam Y. J. Zhang

RIKEN

47H指数

218论文数

1.2W被引数

收录论文 98

发表时间

Phosphorylation of Runx protein controls helper CD4+ T cell versus cytotoxic CD8+ T cell lineage choice Runx蛋白的磷酸化控制辅助CD4 T细胞与细胞毒性CD8 T细胞谱系的选择

Nature Immunology

IF27.6

2026-02-19

OAAI

Chihiro Ogawa; Kazuki Okuyama; Satoshi Kojo; Kohei Nishino; Hiroaki Machiyama; Aditya K. Padhi; Hirotaka Takahashi; Takashi Ebihara; Mari Tenno; Qin Zhizhen; Sawako Muroi; Kosei Ito; Tatsuya Sawasaki; Kam Y. J. Zhang; Hai-Hui Xue; Tadashi Yokosuka; Hidetaka Kosako; Ichiro Taniuchi

The Ser7 phosphorylation of RNA polymerase II-CTD is required for the recruitment of E3 ubiquitin ligase Asr1 and subtelomeric gene silencing RNA聚合酶II-CTD的Ser7磷酸化对于招募E3泛素连接酶Asr1以及亚端粒基因沉默是必需的。

Journal of Biological Chemistry

IF3.9

2025-07-01

OAAI

Nikita Sudarshan; Mohd. Asalam; Ashutosh Kumar; Neha Singh; Adity Gupta; Ishita De; Sanjeev Kumar Singh; Kam YJ. Zhang; Md. Sohail Akhtar

Identification of substituted acetanilide compounds as small molecule CBX2 inhibitors via in silico screening 通过计算机筛选鉴定出取代的乙酰苯胺类化合物作为小分子CBX2抑制剂

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IF2.2

2025-06-01

OAAI

Takase, Shohei; Kumar, Ashutosh; Yokoyama, Sho; Maemoto, Yuki; Aoki, Komei; Arata, Mayumi; Maruo, Hiroki; Dohi, Sayaka; Yun, Young Sook; Inoue, Hideshi; Hamamoto, Makiko; Yoshida, Minoru; Zhang, Kam Y. J.; Ito, Akihiro

Discovery of a Compound That Inhibits IRE1α S-Nitrosylation and Preserves the Endoplasmic Reticulum Stress Response under Nitrosative Stress

ACS CHEMICAL BIOLOGY

IF3.8

2024-11-12

OAAI

Kurogi, Haruna; Takasugi, Nobumasa; Kubota, Sho; Kumar, Ashutosh; Suzuki, Takehiro; Dohmae, Naoshi; Sawada, Daisuke; Zhang, Kam Y. J.; Uehara, Takashi

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-11-05

OAAI

Li, Fengling; Ackloo, Suzanne; Arrowsmith, Cheryl H.; Ban, Fuqiang; Barden, Christopher J.; Beck, Hartmut; Beranek, Jan; Berenger, Francois; Bolotokova, Albina; Bret, Guillaume; Breznik, Marko; Carosati, Emanuele; Chau, Irene; Chen, Yu; Cherkasov, Artem; Della Corte, Dennis; Denzinger, Katrin; Dong, Aiping; Draga, Sorin; Dunn, Ian; Edfeldt, Kristina; Edwards, Aled; Eguida, Merveille; Eisenhuth, Paul; Friedrich, Lukas; Fuerll, Alexander; Gardiner, Spencer S.; Gentile, Francesco; Ghiabi, Pegah; Gibson, Elisa; Glavatskikh, Marta; Gorgulla, Christoph; Guenther, Judith; Gunnarsson, Anders; Gusev, Filipp; Gutkin, Evgeny; Halabelian, Levon; Harding, Rachel J.; Hillisch, Alexander; Hoffer, Laurent; Hogner, Anders; Houliston, Scott; Irwin, John J.; Isayev, Olexandr; Ivanova, Aleksandra; Jacquemard, Celien; Jarrett, Austin J.; Jensen, Jan H.; Kireev, Dmitri; Kleber, Julian; Koby, S. Benjamin; Koes, David; Kumar, Ashutosh; Kurnikova, Maria G.; Kutlushina, Alina; Lessel, Uta; Liessmann, Fabian; Liu, Sijie; Lu, Wei; Meiler, Jens; Mettu, Akhila; Minibaeva, Guzel; Moretti, Rocco; Morris, Connor J.; Narangoda, Chamali; Noonan, Theresa; Obendorf, Leon; Pach, Szymon; Pandit, Amit; Perveen, Sumera; Poda, Gennady; Polishchuk, Pavel; Puls, Kristina; Puetter, Vera; Rognan, Didier; Roskams-Edris, Dylan; Schindler, Christina; Sindt, Francois; Spiwok, Vojtech; Steinmann, Casper; Stevens, Rick L.; Talagayev, Valerij; Tingey, Damon; Vu, Oanh; Walters, W. Patrick; Wang, Xiaowen; Wang, Zhenyu; Wolber, Gerhard; Wolf, Clemens Alexander; Wortmann, Lars; Zeng, Hong; Zepeda, Carlos A.; Zhang, Kam Y. J.; Zhang, Jixian; Zheng, Shuangjia; Schapira, Matthieu

RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-07-01

OAAI

Kukimoto-Niino, Mutsuko; Katsura, Kazushige; Ishizuka-Katsura, Yoshiko; Mishima-Tsumagari, Chiemi; Yonemochi, Mayumi; Inoue, Mio; Nakagawa, Reiko; Kaushik, Rahul; Zhang, Kam Y. J.; Shirouzu, Mikako

The Ser7 of RNA Pol II-CTD influences the recruitment of Cdc73 for mRNA transcription RNA polii-ctd的Ser7影响Cdc73的mRNA转录募集

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-01-01

PREAI

Gupta, Adity; Kumar, Ashutosh; Singh, Neha; Patel, Madhu; Studitsky, Vasily M.; Zhang, Kam Y. J.; Akhtar, Md. Sohail

The Saccharomyces cerevisiae SR protein Npl3 interacts with hyperphosphorylated CTD of RNA Polymerase II 酿酒酵母SR蛋白Npl3与RNA聚合酶II的高磷酸化CTD相互作用

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2023-12-01

PREAI

Gupta, Adity; Kumar, Ashutosh; Singh, Neha; Sudarshan, Nikita; Studitsky, Vasily M.; Zhang, Kam Y. J.; Akhtar, Md. Sohail

Impaired tissue homing by the Ikzf3N159S variant is mediated by interfering with Ikaros function

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-08-17

OAAI

Chang, Jingjie; Yamashita, Motoi; Padhi, Aditya K.; Zhang, Kam Y. J.; Taniuchi, Ichiro

Dorzolamide suppresses PKCd -TIRAP-p38 MAPK signaling axis to dampen the inflammatory response

FUTURE MEDICINAL CHEMISTRY

IF3.4

2023-04-27

OAAI

Rajpoot, Sajjan; Kumar, Ashutosh; Gaponenko, Vadim; Thurston, Teresa L. M.; Mehta, Dolly; Faisal, Syed M.; Zhang, Kam Y. J.; Jha, Hem C.; Darwhekar, Gajanan N.; Baig, Mirza S.

Identification of Fungal and Bacterial Denitrification Inhibitors Targeting Copper Nitrite Reductase

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2023-03-27

PREAI

Kumar, Ashutosh; Matsuoka, Masaki; Matsuyama, Akihisa; Yoshida, Minoru; Zhang, Kam Y. J.

Targeting Ras-binding domain of ELMO1 by computational nanobody design

COMMUNICATIONS BIOLOGY

IF5.1

2023-03-17

OAAI

Tam, Chunlai; Kukimoto-Niino, Mutsuko; Miyata-Yabuki, Yukako; Tsuda, Kengo; Mishima-Tsumagari, Chiemi; Ihara, Kentaro; Inoue, Mio; Yonemochi, Mayumi; Hanada, Kazuharu; Matsumoto, Takehisa; Shirouzu, Mikako; Zhang, Kam Y. J.

Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis DNA甲基转移酶3B的S-亚硝基化在肿瘤发生的表观遗传调控中的关键作用

NATURE COMMUNICATIONS

IF15.7

2023-02-04

OAAI

Okuda, Kosaku; Nakahara, Kengo; Ito, Akihiro; Iijima, Yuta; Nomura, Ryosuke; Kumar, Ashutosh; Fujikawa, Kana; Adachi, Kazuya; Shimada, Yuki; Fujio, Satoshi; Yamamoto, Reina; Takasugi, Nobumasa; Onuma, Kunishige; Osaki, Mitsuhiko; Okada, Futoshi; Ukegawa, Taichi; Takeuchi, Yasuo; Yasui, Norihisa; Yamashita, Atsuko; Marusawa, Hiroyuki; Matsushita, Yosuke; Katagiri, Toyomasa; Shibata, Takahiro; Uchida, Koji; Niu, Sheng-Yong; Lang, Nhi B.; Nakamura, Tomohiro; Zhang, Kam Y. J.; Lipton, Stuart A.; Uehara, Takashi

A novel consensus-based computational pipeline for screening of antibody therapeutics for efficacy against SARS-CoV-2 variants of concern including Omicron variant

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2023-01-16

PREAI

Kumar, Naveen; Kaushik, Rahul; Zhang, Kam Y. J.; Uversky, Vladimir N.; Sahu, Upasana; Sood, Richa; Bhatia, Sandeep

Bayesian Molecular Dating Analyses Combined with Mutational Profiling Suggest an Independent Origin and Evolution of SARS-CoV-2 Omicron BA.1 and BA.2 Sub-Lineages

VIRUSES-BASEL

IF3.5

2022-12-12

OAAI

Kumar, Naveen; Kaushik, Rahul; Singh, Ashutosh; Uversky, Vladimir N.; Zhang, Kam Y. J.; Sahu, Upasana; Bhatia, Sandeep; Sanyal, Aniket

A novel structure-based approach for identification of vertebrate susceptibility to SARS-CoV-2: Implications for future surveillance programmes

ENVIRONMENTAL RESEARCH

IF7.7

2022-09-01

OAAI

Kaushik, Rahul; Kumar, Naveen; Zhang, Kam Y. J.; Srivastava, Pratiksha; Bhatia, Sandeep; Malik, Yashpal Singh

Targeting LIF/LIFR signaling in cancer

GENES & DISEASES

IF9.4

2022-07-01

OAAI

Viswanadhapalli, Suryavathi; Dileep, Kalarickal, V; Zhang, Kam Y. J.; Nair, Hareesh B.; Vadlamudi, Ratna K.

Cell-Free Mutant Analysis Combined with Structure Prediction of a Lasso Peptide Biosynthetic Protease B2

ACS SYNTHETIC BIOLOGY

IF3.9

2022-06-08

OAAI

Alfi, Almasul; Popov, Aleksandr; Kumar, Ashutosh; Zhang, Kam Y. J.; Dubiley, Svetlana; Severinov, Konstantin; Tagami, Shunsuke

Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2022-06-01

PREAI

Dileep, K., V; Ihara, Kentaro; Mishima-Tsumagari, Chiemi; Kukimoto-Niino, Mutsuko; Yonemochi, Mayumi; Hanada, Kazuharu; Shirouzu, Mikako; Zhang, Kam Y. J.

TIRAP-mediated activation of p38 MAPK in inflammatory signaling

SCIENTIFIC REPORTS

IF3.9

2022-04-04

OAAI

Rajpoot, Sajjan; Kumar, Ashutosh; Zhang, Kam Y. J.; Gan, Siew Hua; Baig, Mirza S.

研究方向