Trudler, Dorit; Ghatak, Swagata; Bula, Michael; Parker, James; Talantova, Maria; Luevanos, Melissa; Labra, Sergio; Grabauskas, Titas; Noveral, Sarah Moore; Teranaka, Mayu; Schahrer, Emily; Dolatabadi, Nima; Bakker, Clare; Lopez, Kevin; Sultan, Abdullah; Patel, Parth; Chan, Agnes; Choi, Yongwook; Kawaguchi, Riki; Stankiewicz, Pawel; Garcia-Bassets, Ivan; Kozbial, Piotr; Rosenfeld, Michael G.; Nakanishi, Nobuki; Geschwind, Daniel H.; Chan, Shing Fai; Lin, Wei; Schork, Nicholas J.; Ambasudhan, Rajesh; Lipton, Stuart A.

Redox modulation of the NMDA receptor

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-08-31147

Single-Cell Patch-Clamp/Proteomics of Human Alzheimer's Disease iPSC-Derived Excitatory Neurons Versus Isogenic Wild-Type Controls Suggests Novel Causation and Therapeutic Targets

人类阿尔茨海默氏病iPSC衍生的兴奋性神经元与等基因野生型对照的单细胞膜片钳/蛋白质组学提示新的病因和治疗靶点

ADVANCED SCIENCE

IF14.1

2024-05-212

OAAI

Metabolic Bypass Rescues Aberrant S-nitrosylation-Induced TCA Cycle Inhibition and Synapse Loss in Alzheimer's Disease Human Neurons

代谢旁路挽救了阿尔茨海默氏病人类神经元中异常的S-亚硝基化诱导的TCA循环抑制和突触丢失

ADVANCED SCIENCE

IF14.1

2024-01-189

OAAI

Enzymatic and non-enzymatic transnitrosylation: SCANning the SNO-proteome

酶和非酶转亚硝基化: 扫描SNO蛋白质组

MOLECULAR CELL

IF16.6

2024-01-011

PRE

Dark Matter Pathways of Protein Transnitrosylation Injure Synapses in Alzheimer's Disease

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2023-11-010

PRE

Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection

NATURE CHEMICAL BIOLOGY

IF13.7

2023-10-050

PRE

S-Nitrosylation-mediated dysfunction of TCA cycle enzymes in synucleinopathy studied in postmortem human brains and hiPSC-derived neurons

在死后人脑和hiPSC衍生的神经元中研究的突触核蛋白病中，S-亚硝基化介导的TCA循环酶功能障碍

CELL CHEMICAL BIOLOGY

IF7.2

2023-08-017

OAAI

Apoptotic cell death in disease-Current understanding of the NCCD 2023

疾病中的凋亡细胞死亡-对NCCD 2023的当前理解

CELL DEATH AND DIFFERENTIATION

IF15.4

2023-04-26143

OAAI

Vitale, Ilio; Pietrocola, Federico; Guilbaud, Emma; Aaronson, Stuart A.; Abrams, John M.; Adam, Dieter; Agostini, Massimiliano; Agostinis, Patrizia; Alnemri, Emad S.; Altucci, Lucia; Amelio, Ivano; Andrews, David W.; Aqeilan, Rami, I; Arama, Eli; Baehrecke, Eric H.; Balachandran, Siddharth; Bano, Daniele; Barlev, Nickolai A.; Bartek, Jiri; Bazan, Nicolas G.; Becker, Christoph; Bernassola, Francesca; Bertrand, Mathieu J. M.; Bianchi, Marco E.; Blagosklonny, Mikhail V.; Blander, J. Magarian; Blandino, Giovanni; Blomgren, Klas; Borner, Christoph; Bortner, Carl D.; Bove, Pierluigi; Boya, Patricia; Brenner, Catherine; Broz, Petr; Brunner, Thomas; Damgaard, Rune Busk; Calin, George A.; Campanella, Michelangelo; Candi, Eleonora; Carbone, Michele; Carmona-Gutierrez, Didac; Cecconi, Francesco; Chan, Francis K-M; Chen, Guo-Qiang; Chen, Quan; Chen, Youhai H.; Cheng, Emily H.; Chipuk, Jerry E.; Cidlowski, John A.; Ciechanover, Aaron; Ciliberto, Gennaro; Conrad, Marcus; Cubillos-Ruiz, Juan R.; Czabotar, Peter E.; D'Angiolella, Vincenzo; Daugaard, Mads; Dawson, Ted M.; Dawson, Valina L.; De Maria, Ruggero; De Strooper, Bart; Debatin, Klaus-Michael; Deberardinis, Ralph J.; Degterev, Alexei; Del Sal, Giannino; Deshmukh, Mohanish; Di Virgilio, Francesco; Diederich, Marc; Dixon, Scott J.; Dynlacht, Brian D.; El-Deiry, Wafik S.; Elrod, John W.; Engeland, Kurt; Fimia, Gian Maria; Galassi, Claudia; Ganini, Carlo; Garcia-Saez, Ana J.; Garg, Abhishek D.; Garrido, Carmen; Gavathiotis, Evripidis; Gerlic, Motti; Ghosh, Sourav; Green, Douglas R.; Greene, Lloyd A.; Gronemeyer, Hinrich; Haecker, Georg; Hajnoczky, Gyorgy; Hardwick, J. Marie; Haupt, Ygal; He, Sudan; Heery, David M.; Hengartner, Michael O.; Hetz, Claudio; Hildeman, David A.; Ichijo, Hidenori; Inoue, Satoshi; Jaeaettelae, Marja; Janic, Ana; Joseph, Bertrand; Jost, Philipp J.; Kanneganti, Thirumala-Devi; Karin, Michael; Kashkar, Hamid; Kaufmann, Thomas; Kelly, Gemma L.; Kepp, Oliver; Kimchi, Adi; Kitsis, Richard N.; Klionsky, Daniel J.; Kluck, Ruth; Krysko, Dmitri, V; Kulms, Dagmar; Kumar, Sharad; Lavandero, Sergio; Lavrik, Inna N.; Lemasters, John J.; Liccardi, Gianmaria; Linkermann, Andreas; Lipton, Stuart A.; Lockshin, Richard A.; Lopez-Otin, Carlos; Luedde, Tom; MacFarlane, Marion; Madeo, Frank; Malorni, Walter; Manic, Gwenola; Mantovani, Roberto; Marchi, Saverio; Marine, Jean-Christophe; Martin, Seamus J.; Martinou, Jean-Claude; Mastroberardino, Pier G.; Medema, Jan Paul; Mehlen, Patrick; Meier, Pascal; Melino, Gerry; Melino, Sonia; Miao, Edward A.; Moll, Ute M.; Munoz-Pinedo, Cristina; Murphy, Daniel J.; Niklison-Chirou, Maria Victoria; Novelli, Flavia; Nunez, Gabriel; Oberst, Andrew; Ofengeim, Dimitry; Opferman, Joseph T.; Oren, Moshe; Pagano, Michele; Panaretakis, Theocharis; Pasparakis, Manolis; Penninger, Josef M.; Pentimalli, Francesca; Pereira, David M.; Pervaiz, Shazib; Peter, Marcus E.; Pinton, Paolo; Porta, Giovanni; Prehn, Jochen H. M.; Puthalakath, Hamsa; Rabinovich, Gabriel A.; Rajalingam, Krishnaraj; Ravichandran, Kodi S.; Rehm, Markus; Ricci, Jean-Ehrland; Rizzuto, Rosario; Robinson, Nirmal; Rodrigues, Cecilia M. P.; Rotblat, Barak; Rothlin, Carla, V; Rubinsztein, David C.; Rudel, Thomas; Rufini, Alessandro; Ryan, Kevin M.; Sarosiek, Kristopher A.; Sawa, Akira; Sayan, Emre; Schroder, Kate; Scorrano, Luca; Sesti, Federico; Shao, Feng; Shi, Yufang; Sica, Giuseppe S.; Silke, John; Simon, Hans-Uwe; Sistigu, Antonella; Stephanou, Anastasis; Stockwell, Brent R.; Strapazzon, Flavie; Strasser, Andreas; Sun, Liming; Sun, Erwei; Sun, Qiang; Szabadkai, Gyorgy; Tait, Stephen W. G.; Tang, Daolin; Tavernarakis, Nektarios; Troy, Carol M.; Turk, Boris; Urbano, Nicoletta; Vandenabeele, Peter; Vanden Berghe, Tom; Vander Heiden, Matthew G.; Vanderluit, Jacqueline L.; Verkhratsky, Alexei; Villunger, Andreas; von Karstedt, Silvia; Voss, Anne K.; Vousden, Karen H.; Vucic, Domagoj; Vuri, Daniela; Wagner, Erwin F.; Walczak, Henning; Wallach, David; Wang, Ruoning; Wang, Ying; Weber, Achim; Wood, Will; Yamazaki, Takahiro; Yang, Huang-Tian; Zakeri, Zahra; Zawacka-Pankau, Joanna E.; Zhang, Lin; Zhang, Haibing; Zhivotovsky, Boris; Zhou, Wenzhao; Piacentini, Mauro; Kroemer, Guido; Galluzzi, Lorenzo

Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27232

OAAI

Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis

DNA甲基转移酶3B的S-亚硝基化在肿瘤发生的表观遗传调控中的关键作用

NATURE COMMUNICATIONS

IF15.7

2023-02-0410

OAAI

Okuda, Kosaku; Nakahara, Kengo; Ito, Akihiro; Iijima, Yuta; Nomura, Ryosuke; Kumar, Ashutosh; Fujikawa, Kana; Adachi, Kazuya; Shimada, Yuki; Fujio, Satoshi; Yamamoto, Reina; Takasugi, Nobumasa; Onuma, Kunishige; Osaki, Mitsuhiko; Okada, Futoshi; Ukegawa, Taichi; Takeuchi, Yasuo; Yasui, Norihisa; Yamashita, Atsuko; Marusawa, Hiroyuki; Matsushita, Yosuke; Katagiri, Toyomasa; Shibata, Takahiro; Uchida, Koji; Niu, Sheng-Yong; Lang, Nhi B.; Nakamura, Tomohiro; Zhang, Kam Y. J.; Lipton, Stuart A.; Uehara, Takashi

Aberrant protein S-nitrosylation contributes to hyperexcitability-induced synaptic damage in Alzheimer's disease: Mechanistic insights and potential therapies

FRONTIERS IN NEURAL CIRCUITS

IF3

2023-02-0212

OAAI

Stuart A. Lipton

个人简介

教育背景

工作经历

荣誉奖项

研究方向