Zhen Guo - Publications, H-index & Citations

Zhen Guo

Nanjing Medical University and Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research

31H指数

154论文数

4.1K被引数

收录论文 42

发表时间

Double-dose firmonertinib as first-line treatment in patients with locally advanced or metastatic non-small-cell lung cancer harboring EGFR L858R mutation: a prospective, multicenter, phase II study (FIRM)双重剂量的firmonertinib作为一线治疗EGFR L858R突变的局部晚期或转移性非小细胞肺癌患者: 一项前瞻性，多中心，II期研究 (FIRM)

Nature Communications

IF15.7

2026-01-19

OAAI

Bo Shen; Chun Wang; Liqin Zhang; Yingying Zhu; Xing Zhang; Xiaoxuan Wang; Zhen Guo; Li Wang; Xiaohua Wang; Liqun Zhu; Yun Zhou; Danting Liao; Meiqi Shi

Nanosized natural products for immune dysregulation: A systematic review of mechanisms, therapeutic applications, and translational challenges 纳米级天然产物用于免疫失调：机制、治疗应用和转化挑战的系统综述

Phytomedicine

IF8.3

2025-11-22

PREAI

Zhen Guo; Peng Xian; Don Green; Kai-Li Hu; Lei-Miao Yin

Lactobacillus reuteri attenuates methotrexate-induced liver injury via modulation of oxidative stress and inflammation through HO-1/GPX4 and NF-κB/NLRP3 pathways Lactobacillus reuteri通过调节氧化应激和炎症，经由HO-1/GPX4和NF-κB/NLRP3通路减轻甲氨蝶呤诱导的肝脏损伤。

European Journal of Pharmacology

IF4.7

2025-09-22

PREAI

Wen-Ru Li; Yi-Ke Li; Huan Ren; Zhen Guo; Chen-Lin Xiao; Jian-Quan Luo

CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability (vol 20, 101, 2021)circDIDO1通过编码一种新型的DIDO1-529aa蛋白并调控PRDX2蛋白稳定性来抑制胃癌进展（卷20，101，2021）

MOLECULAR CANCER

IF33.9

2025-05-21

OAAI

Zhang, Yu; Jiang, Jiajia; Zhang, Jiayin; Shen, Han; Wang, Maoye; Guo, Zhen; Zang, Xueyan; Shi, Hui; Gao, Jiayan; Cai, Hui; Fang, Xinjian; Qian, Hui; Xu, Wenrong

Solasodine suppresses nasopharyngeal carcinoma progression by inducing ferroptosis Solasodine通过诱导铁死亡抑制鼻咽癌进展

SCIENTIFIC REPORTS

IF3.9

2025-05-18

OAAI

Wang, Jing; Wang, Donghua; Ma, Siqing; He, Binsheng; Lu, Jiaoyang; Guo, Zhen

Discovery of a Novel Multitarget Analgesic Through an In Vivo-Guided Approach

PHARMACEUTICALS

IF4.8

2025-02-03

OAAI

Zhen, Guo; Do, Nayeon; Van Manh, Nguyen; Ha, Hee-Jin; Kim, Hee; Kim, Hyunsoo; Choi, Kwanghyun; Ann, Jihyae; Lee, Jeewoo

Formononetin alleviates no reflow after myocardial ischemia-reperfusion via modulation of gut microbiota to inhibit inflammation 芒柄花素通过调节肠道菌群抑制炎症反应减轻心肌缺血再灌注后无复流

LIFE SCIENCES

IF5.1

2024-12-01

OAAI

Zhang, Yanyan; Deng, Jiaxin; Chen, Ting; Liu, Siqi; Tang, Yan; Zhao, Ji Rui; Guo, Zhen; Zhang, Wei; Chen, Ting.

Myricetin ameliorates prediabetes through gut microbiota-SCFAs-Gpr43 axis

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

IF8.8

2024-08-10

PREAI

Yang, Li; Gao, Yongchao; Gong, Jupeng; Su, Qiaoling; Guo, Zhen; Farag, Mohamed A.; Xiao, Jianbo

Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling

BME FRONTIERS

IF7.7

2024-07-23

OAAI

Selcuk, Sahan Yoruc; Yang, Xilin; Bai, Bijie; Zhang, Yijie; Li, Yuzhu; Aydin, Musa; Unal, Aras Firat; Gomatam, Aditya; Guo, Zhen; Angus, Darrow Morgan; Kolodney, Goren; Atlan, Karine; Haran, Tal Keidar; Pillar, Nir; Ozcan, Aydogan

The IMPROVEMENT project: first report of the global liver transplant activity

DIGESTIVE AND LIVER DISEASE

IF3.8

2024-02-01

PREAI

Avolio, A. W.; Pascale, M. M.; Burra, P.; Bhoori, S.; De Maria, N.; Donato, F.; Fagiuoli, S.; Lanza, A. Galeota; Giannelli, V.; Corradini, S. Ginanni; Lenci, I.; Magro, B.; Martini, S.; Petruccelli, S.; Piscaglia, F.; Pompili, M.; Rendina, M.; Baroni, G. L. Svegliati; Violi, P.; Barbier, L.; Braun, F.; Boin, I.; Caccamo, L.; Cicarelli, O.; Cillo, U.; Carraro, A.; Cescon, M.; De Carlis, L.; De Carlis, R.; De Simone, P.; De Santibanes, M.; Deng, F.; Di Benedetto, F.; Ettorre, G. M.; Fernandez, H.; Gastaca, M.; Gruttadauria, S.; Guo, Z.; Hammond, J.; Lai, Q.; Lesurtel, M.; Llado, L.; Martins, P.; Mazzaferro, V.; Mejia, G.; Nadalin, S.; Oniscu, G.; Patel, M.; Perera, T.; Pinelli, D.; Polak, W.; Quintini, C.; Ravaioli, M.; Rela, M.; Romagnoli, R.; Salame, E.; Subash, G.; Tandoi, F.; Takashi, I.; Timucin, T.; Tisone, G.; Vennarecci, G.; Vivarelli, M.; Vorasittha, A.; Zieniewicz, K.; Agopian, V.

Peptide-graphene logic sensing system for dual-mode detection of exosomes, molecular information processing and protection

TALANTA

IF6.1

2024-01-01

PREAI

Lu, Jiao Yang; Guo, Zhen; Huang, Wei Tao; Bao, Meihua; He, Binsheng; Li, Guangyi; Lei, Jieni; Li, Yaqian

Co-Occurring EGFR S645C and EGFR L858R in a Patient with Lung Adenocarcinoma Induced Primary Resistance to Osimertinib 1例肺腺癌患者中EGFR S645C和EGFR L858R同时发生诱导对奥希替尼的原发性耐药

LUNG CANCER-TARGETS AND THERAPY

IF3.3

2023-10-01

OAAI

Wang, Li; Quan, Fei; Guo, Zhen; Lu, Zhongyu; Yang, Duoxia; Shi, Meiqi

AQP8 promotes glioma proliferation and growth, possibly through the ROS/PTEN/AKT signaling pathway

BMC CANCER

IF3.4

2023-06-06

OAAI

Zhang, Hao; Sheng, Huajun; Guo, Zhen; Xing, Yu; Liu, Qian; Cai, Ziling; Shen, Zihao; Xia, Qingqian; Zhu, Shujuan

LncRNA FAS-AS1 upregulated by its genetic variation rs6586163 promotes cell apoptosis in nasopharyngeal carcinoma through regulating mitochondria function and Fas splicing

SCIENTIFIC REPORTS

IF3.9

2023-05-22

OAAI

Guo, Zhen; Li, ZiBo; Zhang, MengLing; Bao, MeiHua; He, BinSheng; Zhou, XiaoLong

The ferroptosis signature predicts the prognosis and immune microenvironment of nasopharyngeal carcinoma

SCIENTIFIC REPORTS

IF3.9

2023-02-02

OAAI

Zhou, Ji; Guo, Tianyao; Zhou, Lin; Bao, Meihua; Wang, Lin; Zhou, Wenhu; Tan, Shan; Li, Guangyi; He, Binsheng; Guo, Zhen

E2F4-induced AGAP2-AS1 up-regulation accelerates the progression of colorectal cancer via miR-182-5p/CFL1 axis

DIGESTIVE AND LIVER DISEASE

IF3.8

2022-07-01

PREAI

Guo, Zhen; Liu, Xuezhong; Shao, Hongjin

HOXA11-AS facilitates the proliferation, cell cycle process and migration of keloid fibroblasts through sponging miR-188-5p to regulate VEGFA

JOURNAL OF DERMATOLOGICAL SCIENCE

IF4

2022-05-01

PREAI

Zhou, Xiaolong; Lu, Jiaoyang; Ben Wu; Zhen Guo

Selected using bioinformatics and molecular docking analyses, PHA-793887 is effective against osteosarcoma

AGING-US

IF3.9

2021-06-21

OAAI

Wu, Bo; Yang, Wenzhuo; Fu, Zhaoyu; Xie, Haoqun; Guo, Zhen; Liu, Daqun; Ge, Junliang; Zhong, Sheng; Liu, Luwei; Liu, Jingyi; Zhu, Dong

LINC-PINT impedes DNA repair and enhances radiotherapeutic response by targeting DNA-PKcs in nasopharyngeal cancer

CELL DEATH & DISEASE

IF9.6

2021-05-07

OAAI

Wang, You-hong; Guo, Zhen; An, Liang; Zhou, Yong; Xu, Heng; Xiong, Jing; Liu, Zhao-qian; Chen, Xiao-ping; Zhou, Hong-hao; Li, Xiong; Liu, Tao; Huang, Wei-hua; Zhang, Wei

LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma

CELL DEATH & DISEASE

IF9.6

2021-01-04

OAAI

Guo, Zhen; Wang, You-Hong; Xu, Heng; Yuan, Chun-Su; Zhou, Hong-Hao; Huang, Wei-Hua; Wang, Hui; Zhang, Wei

研究方向