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张

张长生 (Changsheng Zhang)

South China Sea Institute of Oceanology, Chinese Academy of Sciences

51H指数
377论文数
9.7K被引数
收录论文 157
发表时间
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Genome-directed discovery of an octalin-containing polyether ionophore improves diabetic skin wound healing基因组导向发现的一种含八氢萘环的多醚离子载体可改善糖尿病皮肤伤口愈合
errNature Communications
IF15.7
err2026-09-09
err0
errOAAI
errChunyan Fang; Zhiwen Liu; Liangliang Bai; Liang Ma; Weiliang Xiong; Lili Sun; Linping Wu; Jing Ni; Wenjun Zhang; Yiguang Zhu; Yanxin Luo; Yingjie Li; Changsheng Zhang
err分享
err收藏
A Cytochrome P450 Enzyme-Catalyzed Acetyl Migration in Cyanogramide Biosynthesis细胞色素P450酶催化的氰基糖胺生物合成中的乙酰基迁移
errAngewandte Chemie-International Edition
IF16.9
err2026-08-25
err0
PREAI
errYiguang Zhu; Yongchao Wang; Liping Zhang; Chunyan Fang; Youhua Yong; Ruijie Chen; Jiahai Zhou; Qingbo Zhang; Binju Wang; Changsheng Zhang
err分享
err收藏
Deciphering Early Oxidative Steps in Spirotetronate Biosynthesis Reveals a Two-Enzyme Cascade for Macrocyclic Lactone Formation解析螺旋四酮生物合成中的早期氧化步骤揭示了形成大环内酯的两酶级联反应
errOrganic Letters
IF5
err2026-05-13
err0
PREAI
errSiqiang Chen; Zuer Lin; Qingbo Zhang; Bin Tan; Xinya Zhang; Wenjun Zhang; Haibo Zhang; Yiguang Zhu; Liping Zhang; Changsheng Zhang
err分享
err收藏
Minute-scale synthesis of hierarchical and nanosized ZSM-5 zeolites with high space-time yields
errCHEMICAL ENGINEERING SCIENCE
IF4.3
err2026-01-21
err0
PREAI
errZhang, Changsheng; Lu, Fangxu; Zhao, Jinchong; Wen, Song; Sun, Bing; Jiang, Jie
err分享
err收藏
Discovery; bioactivities and biosynthesis of spirooxindole alkaloids发现；螺吲哚里西丁类生物碱的生物活性与生物合成
errnat. prod. rep.
IF0
err2026-01-06
err0
errOAAI
errRuijie Chen; Lihan Zhang; Xiaoyang Zhao; Zhuangjie Fang; Liping Zhang; Qingbo Zhang; Changsheng Zhang; Yiguang Zhu
err分享
err收藏
Genome mining guided discovery of new pentangular polyketides from the marine rare actinomycete Actinoalloteichus hymeniacidonis DSM 45092基因组挖掘指导下的海洋稀有放线菌Actinoalloteichus hymeniacidonis DSM 45092中新五元聚酮化合物的发现
errJournal of Asian Natural Products Research
IF1.3
err2026-01-01
err0
PREAI
errYang, Zi-Yi; Sun, Li-Li; Fang, Zhuang-Jie; Chen, Yu-Chan; Zhang, Wei-Min; Zhu, Yi-Guang; Zhang, Chang-Sheng; Zhang, Qing-Bo
err分享
err收藏
Novel lipopeptides featuring unusual C–C and C–N linkages between cyclic peptides and fatty acyl chains新型脂肽，其特征在于环肽与脂肪酸链之间具有不寻常的C–C和C–N连接
errChinese Chemical Letters
IF8.9
err2025-12-17
err0
PREAI
errWeixia Ye; Kai Liu; Wei Liu; Xianbo Chen; Xuemin Ding; Haiyan Tian; Wenjun Zhang; Changsheng Zhang
err分享
err收藏
Efficient catalytic deoxygenation with a Zr-modified Pd-based industrial catalyst高效的Zr改性Pd基工业催化剂催化脱氧
errNew J. Chem.
IF2.5
err2025-11-20
err0
PREAI
errFangxu Lu; Changsheng Zhang; Song Wen; Jinchong Zhao; Jie Jiang; Dong Cao; Bing Sun; Wei Xu
err分享
err收藏
DiffPepDock: Efficient protein–peptide docking and binder screening via SE(3)-equivariant diffusionDiffPepDock：通过SE(3)-equivariant扩散实现高效蛋白质-肽段对接和结合物筛选
errProtein Science
IF5.2
err2025-10-14
err0
PREAI
errYuzhe Wang; Fanhao Wang; Laiyi Feng; Changsheng Zhang; Luhua Lai
err分享
err收藏
Development of A Salt-Enhanced Promoter Strategy for Activating Silent Biosynthetic Gene Clusters from Streptomycetes盐增强型启动子策略在链霉菌中激活沉默生物合成基因簇的开发
errMetabolic Engineering
IF6.8
err2025-07-25
err0
PREAI
errLijuan Wang; Mengyi Zhu; Chunfang Yang; Siqi Zhu; Bin Tan; Shu-Hua Qi; Yiguang Zhu; Changsheng Zhang
err分享
err收藏
Fungal 4-Hydroxy-2-Pyridone alkaloids: Structures, synthesis, biosynthesis, and bioactivities (2010–2024)真菌4-羟基-2-吡啶酮生物碱：结构、合成、生物合成及生物活性（2010–2024）
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-07-07
err0
PREAI
errXiangliu Chen; Xiaoyang Zhao; Mengjing Cong; Yiwei Hu; Changsheng Zhang; Yonghong Liu; Yiguang Zhu; Junfeng Wang
err分享
err收藏
Biochemical and Structural Insights of the N-Methyltransferase CyaF in Cyanogramide Biosynthesis
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2025-03-01
err0
PREAI
errChen, Ruijie; Zhang, Qingbo; Zhang, Liping; Fang, Chunyan; Zhu, Hanning; Zhu, Weiming; Zhang, Changsheng; Zhu, Yiguang
err分享
err收藏
Discovery of MK8383s with Antifungal Activity from Mangrove Endophytic Fungi Medicopsis sp. SCSIO 40440 Against Fusarium Wilt of Banana
errMARINE DRUGS
IF5.4
err2025-02-18
err0
errOAAI
errZhou, Tianyu; Qiao, Yulei; Wang, Lu; Li, Zifeng; Zhang, Haibo; Zhang, Liping; Liao, Shengrong; Li, Minhui; Zhang, Changsheng; Zhang, Wenjun
err分享
err收藏
Static X-ray differential phase contrast imaging via bidirectional-misalignment grating
errMEASUREMENT
IF5.6
err2025-01-01
err0
PREAI
errGuan, Wei; Zhang, Changsheng; Gao, Zhiyu; Xu, Linhai; Lan, Haibin; Gao, Yenan; Chen, Xiaolong; Li, Jianjun; Wang, Qianni; Jiang, Chongwen; Zhao, Gang; Fu, Jian
err分享
err收藏
XSNet: A Lightweight X-Ray Security Image Segmentation Model Combining State-Space Models and Convolutional Neural NetworksXSNet: 结合状态空间模型和卷积神经网络的轻量级x射线安全图像分割模型
errieee signal processing magazine
IF3.9
err2025-01-01
err0
PREAI
errJia, Weichao; Liu, Wei; Zhang, Changsheng; Fu, Jian; Liu, Qiong
err分享
err收藏
Deciphering the Biosynthetic Logic for C14 Oxidative Modifications of Polycyclic Tetramate Macrolactams
errCHINESE JOURNAL OF CHEMISTRY
IF5.5
err2024-11-21
err0
errOAAI
errJiang, Peng; Jin, Hongbo; Zhang, Wenjun; Tang, Wei; Jiang, Xiaodong; Zhu, Yiguang; Wang, Ying; Zhang, Liping; Zhang, Changsheng
err分享
err收藏
Achieving Regioselectivity for Remote C-H Activation by Substructure Conformations: an Approach of Paralogous Cytochrome P450 Enzymes
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2024-10-23
err0
PREAI
errZhang, Liping; Jiang, Peng; Jin, Hongbo; Zhang, Changsheng
err分享
err收藏
Discovery of Kebanmycins with Antibacterial and Cytotoxic Activities from the Mangrove-Derived Streptomyces sp. SCSIO 40068
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2024-06-11
err5
PREAI
errZhao, Mengran; Zhang, Wenjun; Yang, Chunfang; Zhang, Liping; Huang, Huarong; Zhu, Yiguang; Ratnasekera, Disna; Zhang, Changsheng
err分享
err收藏
Discovery and Biosynthesis of Cihanmycins Reveal Cytochrome P450-Catalyzed Intramolecular C-O Phenol Coupling Reactions
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-06-06
err4
PREAI
errFang, Chunyan; Zhang, Liping; Wang, Yongchao; Xiong, Weiliang; Yan, Zier; Zhang, Wenjun; Zhang, Qingbo; Wang, Binju; Zhu, Yiguang; Zhang, Changsheng
err分享
err收藏
Replenishment of mitochondrial Na+ and H+ by ionophores potentiates cutaneous wound healing in diabetes离子载体补充线粒体Na和H可增强糖尿病的皮肤伤口愈合
errMATERIALS TODAY BIO
IF10.2
err2024-06-01
err3
errOAAI
errBai, Liangliang; Wu, Linping; Zhang, Changsheng; Liu, Zhiwen; Ma, Liang; Ni, Jing; He, Dezhen; Zhu, Mingxuan; Peng, Shaoyong; Liu, Xiaoxia; Yu, Huichuan; Lei, Yuhe; Luo, Yanxin; Zhang, Yu; Wang, Xiaolin; Wei, Gang; Li, Yingjie
err分享
err收藏

研究方向

海洋微生物源药物分子发现海洋微生物源药物分子生物合成海洋微生物源药物分子代谢工程海洋微生物源药物分子开发应用多组学指导下海洋微生物源药物分子发现海洋微生物源药物分子生物合成途径海洋微生物源药物分子酶催化机制海洋微生物源药物分子生物活性海洋微生物源药物分子成药性评价合成生物学代谢工程海洋微生物活性物质发现生物活性与成药性评价药源分子生物合成新功能酶的作用机制研究酶定向改造联合基金重点项目 2025-2028重点国际（地区）合作研究项目 2019-2023国际(地区)合作与交流项目 2019-2020重点项目 2017-2021杰出青年基金 2012-2015面上项目（3）中国科学院前沿领域重点项目 2016-2022中国科学院重要方向性项目 2009-2011中国科学院先导专项重点任务 2013-2017广东省海洋经济创新发展区域示范项目，课题 2013-2017广东省自然基金重大培育项目 2015-2018广东省渔港建设和渔业产业发展专项 2016-2018代表性文章
合作学者
合作期刊
Chuan He 封面图
Chuan He (Chuan He)
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H 指数: 161 · 论文数: 1.5K
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H 指数: 144 · 论文数: 852
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Yang REN 封面图
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