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M

Makoto Ihara

kindai university
H指数:32
被引数:4,957

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The functional impact of mutations in the orthosteric binding site of the Drosophila melanogaster Dα2- containing nicotinic receptors points to a greater contribution to neonicotinoid selectivity of an arginine in loop D of Dβ1 than an introduced serine in loop C of Dα2

果蝇 *Drosophila melanogaster* 中Dα2亚基含有的烟碱型受体正构结合位点的突变对功能的影响表明，位于Dβ1环中的精氨酸对拟除虫菊酯选择性的贡献大于在Dα2环C中引入的丝氨酸。

Insect Biochemistry and Molecular Biology
IF3.7
2025-08-060
PRE
Ryo Ito; Hisanori Ojima; Miyu Takeuchi; Hiyori Takahashi; Makoto Ihara; David B. Sattelle; Kazuhiko Matsuda
'Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae' (2024), by Ito et al. (vol 15, 250033, 2024)

'解析新烟碱类杀虫剂对疟疾媒介按蚊 *Anopheles gambiae* 熏杀作用中尼古丁受体和配体的特征' (2024)，作者：Ito et al. (卷 15，250033，2024)

OPEN BIOLOGY
IF3.6
2025-04-100
OA
Ito, Ryo; Kamiya, Masaki; Takayama, Koichi; Mori, Sumito; Matsumoto, Rei; Takebayashi, Mayuka; Ojima, Hisanori; Fujimura, Shota; Yamamoto, Haruki; Ohno, Masayuki; Ihara, Makoto; Okajima, Toshihide; Yamashita, Atsuko; Colman, Fraser; Lycett, Gareth J.; Sattelle, David B.
Binding site loops D and G make a stronger contribution than loop C to the actions of neonicotinoids on the NACHO-assisted, robustly expressed Drosophila melanogaster Dα1/Dβ1 nicotinic acetylcholine receptor

结合位点环D和G对新烟碱类化合物在NACHO辅助下稳定表达的Drosophila melanogaster Dα1/Dβ1烟碱型乙酰胆碱受体上的作用贡献强于环C。

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
IF4
2025-04-010
PRE
Ito, Ryo; Ojima, Hisanori; Takebayashi, Mayuka; Takeuchi, Miyu; Takahashi, Hiyori; Mori, Sumito; Ihara, Makoto; Sattelle, David B.
Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions

果蝇，蜜蜂和大黄蜂烟碱受体的辅因子功能表达揭示了皮摩尔新烟碱类作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-07-0169
OAAI
Ihara, Makoto; Furutani, Shogo; Shigetou, Sho; Shimada, Shota; Niki, Kunihiro; Komori, Yuma; Kamiya, Masaki; Koizumi, Wataru; Magara, Leo; Hikida, Mai; Noguchi, Akira; Okuhara, Daiki; Yoshinari, Yuto; Kondo, Shu; Tanimoto, Hiromu; Niwa, Ryusuke; Sattelle, David B.; Matsuda, Kazuhiko

研究方向

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K
Kazuhiko Matsuda
H 指数:39论文数:194被引数:6,519
D
David B. Sattelle
H 指数:75论文数:375被引数:2.0万
S
Shogo Furutani
H 指数:16论文数:41被引数:779
K
Koichi Takayama
H 指数:4论文数:9被引数:51
S
S. Mori
H 指数:7论文数:53被引数:185
H
Hideo Hayashi
H 指数:37论文数:280被引数:6,433
M
Masaki Kamiya
H 指数:13论文数:79被引数:512
R
Ryo Ito
H 指数:4论文数:16被引数:105
H
Hisanori Ojima
H 指数:3论文数:13被引数:21
A
Atsuko Yamashita
H 指数:27论文数:123被引数:6,213