未登录 MERS-CoV spike vaccine-induced N-terminal domain specific antibodies are more protective than receptor binding domain-specific antibodies- MERS-CoV刺突疫苗诱导的N端结构域特异性抗体比受体结合结构域特异性抗体具有更强的保护作用。 Abiona, Olubukola M.; Wang, Nianshuang; Leist, Sarah R.; Schafer, Alexandra; Cockrell, Adam S.; Wang, Lingshu; Bangaru, Sandhya; Stevens, Laura; Graham, Rachel L.; Kocher, Jacob F.; Tsybovsky, Yaroslav; Kanekiyo, Masaru; Kumar, Azad; Morabito, Kaitlyn M.; Rosen, Osnat; Shi, Wei; Werner, Anne; Zhang, Yi; Ziwawo, Cynthia; Dzuvor, Christian K. O.; Palandjian, Charis; Eastman, Connor; Matthews, Hannah R.; Chappell, James D.; Kong, Wing-Pui; Mascola, John R.; Ward, Andrew B.; Denison, Mark R.; Baric, Ralph; Mclellan, Jason S.; Graham, Barney S.; Corbett-Helaire, Kizzmekia S. 分享 收藏
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Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination Voss, William N.; Mallory, Michael A.; Byrne, Patrick O.; Marchioni, Jeffrey M.; Knudson, Sean A.; Powers, John M.; Leist, Sarah R.; Dadonaite, Bernadeta; Townsend, Douglas R.; Kain, Jessica; Huang, Yimin; Satterwhite, Ed; Castillo, Izabella N.; Mattocks, Melissa; Paresi, Chelsea; Munt, Jennifer E.; Scobey, Trevor; Seeger, Allison; Premkumar, Lakshmanane; Bloom, Jesse D.; Georgiou, George; McLellan, Jason S.; Baric, Ralph S.; Lavinder, Jason J.; Ippolito, Gregory C. 分享 收藏
The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo Rhodin, Michael H. J.; Reyes, Archie C.; Balakrishnan, Anand; Bisht, Nalini; Kelly, Nicole M.; Gibbons, Joyce Sweeney; Lloyd, Jonathan; Vaine, Michael; Cressey, Tessa; Crepeau, Miranda; Shen, Ruichao; Manalo, Nathan; Castillo, Jonathan; Levene, Rachel E.; Leonard, Daniel; Zang, Tianzhu; Jiang, Lijuan; Daniels, Kellye; Cox, Robert M.; Lieber, Carolin M.; Wolf, Josef D.; Plemper, Richard K.; Leist, Sarah R.; Scobey, Trevor; Baric, Ralph S.; Wang, Guoqiang; Goodwin, Bryan; Or, Yat Sun 分享 收藏
Efficacy of host cell serine protease inhibitor MM3122 against SARS-CoV-2 for treatment and prevention of COVID-19 Boon, Adrianus C. M.; Bricker, Traci L.; Fritch, Ethan J.; Leist, Sarah R.; Gully, Kendra; Baric, Ralph S.; Graham, Rachel L.; Troan, Brigid V.; Mahoney, Matthew; Janetka, James W. 分享 收藏
Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus Dillard, Jacob A.; Taft-Benz, Sharon A.; Knight, Audrey C.; Anderson, Elizabeth J.; Pressey, Katia D.; Parotti, Breantie; Martinez, Sabian A.; Diaz, Jennifer L.; Sarkar, Sanjay; Madden, Emily A.; de la Cruz, Gabriela; Adams, Lily E.; Dinnon, Kenneth H.; Leist, Sarah R.; Martinez, David R.; Schafer, Alexandra; Powers, John M.; Yount Jr, Boyd L.; Castillo, Izabella N.; Morales, Noah L.; Burdick, Jane; Evangelista, Mia Katrina D.; Ralph, Lauren M.; Pankow, Nicholas C.; Linnertz, Colton L.; Lakshmanane, Premkumar; Montgomery, Stephanie A.; Ferris, Martin T.; Baric, Ralph S.; Baxter, Victoria K.; Heise, Mark T. 分享 收藏
Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge Hsieh, Ching-Lin; Leist, Sarah R.; Miller, Emily Happy; Zhou, Ling; Powers, John M.; Tse, Alexandra L.; Wang, Albert; West, Ande; Zweigart, Mark R.; Schisler, Jonathan C.; Jangra, Rohit K.; Chandran, Kartik; Baric, Ralph S.; Mclellan, Jason S. 分享 收藏
Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice Alves, Rubens Prince dos Santos; Timis, Julia; Miller, Robyn; Valentine, Kristen; Pinto, Paolla Beatriz Almeida; Gonzalez, Andrew; Regla-Nava, Jose Angel; Maule, Erin; Nguyen, Michael N.; Shafee, Norazizah; Landeras-Bueno, Sara; Olmedillas, Eduardo; Laffey, Brett; Dobaczewska, Katarzyna; Mikulski, Zbigniew; Mcardle, Sara; Leist, Sarah R.; Kim, Kenneth; Baric, Ralph S.; Ollmann Saphire, Erica; Elong Ngono, Annie; Shresta, Sujan 分享 收藏
Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population Cisneros, Marta C. Cruz; Anderson, Elizabeth J.; Hampton, Brea K.; Parotti, Breantie; Sarkar, Sanjay; Taft-Benz, Sharon; Bell, Timothy A.; Blanchard, Matthew; Dillard, Jacob A.; Dinnon III, Kenneth H.; Hock, Pablo; Leist, Sarah R.; Madden, Emily A.; Shaw, Ginger D.; West, Ande; Baric, Ralph S.; Baxter, Victoria K.; de Villena, Fernando Pardo-Manuel; Heise, Mark T.; Ferris, Martin T. 分享 收藏
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BCG vaccination stimulates integrated organ immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance BCG疫苗接种通过适应性免疫反应的反馈来刺激整合器官免疫，以印记长期的先天抗病毒药物抗性 Lee, Audrey; Floyd, Katharine; Wu, Shengyang; Fang, Zhuoqing; Tan, Tze Kai; Froggatt, Heather M.; Powers, John M.; Leist, Sarah R.; Gully, Kendra L.; Hubbard, Miranda L.; Li, Chunfeng; Hui, Harold; Scoville, David; Ruggiero, Alistaire D.; Liang, Yan; Pavenko, Anna; Lujan, Victor; Baric, Ralph S.; Nolan, Garry P.; Arunachalam, Prabhu S.; Suthar, Mehul S.; Pulendran, Bali 分享 收藏
A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus Tse, Longping V.; Hou, Yixuan J.; Mcfadden, Elizabeth; Lee, Rhianna E.; Scobey, Trevor D.; Leist, Sarah R.; Martinez, David R.; Meganck, Rita M.; Schafer, Alexandra; Yount, Boyd L.; Mascenik, Teresa; Powers, John M.; Randell, Scott H.; Zhang, Yi; Wang, Lingshu; Mascola, John; Mclellan, Jason S.; Baric, Ralph S. 分享 收藏
Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice 宿主遗传变异指导小鼠肝病毒清除，慢性和肝纤维化 Brown, Ariane J.; Won, John J.; Wolfisberg, Raphael; Fahnoe, Ulrik; Catanzaro, Nicholas; West, Ande; Moreira, Fernando R.; Nogueira Batista, Mariana; Ferris, Martin T.; Linnertz, Colton L.; Leist, Sarah R.; Nguyen, Cameron; De la Cruz, Gabriela; Midkiff, Bentley R.; Xia, Yongjuan; Evangelista, Mia D.; Montgomery, Stephanie A.; Billerbeck, Eva; Bukh, Jens; Scheel, Troels K. H.; Rice, Charles M.; Sheahan, Timothy P. 分享 收藏
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine 用AS03佐剂新型冠状病毒肺炎疫苗预防接种猕猴产生的针对sarbecovirus的广泛中和抗体 Feng, Yupeng; Yuan, Meng; Powers, John M.; Hu, Mengyun; Munt, Jennifer E.; Arunachalam, Prabhu S.; Leist, Sarah R.; Bellusci, Lorenza; Kim, JungHyun; Sprouse, Kaitlin R.; Adams, Lily E.; Sundaramurthy, Sumana; Zhu, Xueyong; Shirreff, Lisa M.; Mallory, Michael L.; Scobey, Trevor D.; Moreno, Alberto; O'Hagan, Derek T.; Kleanthous, Harry; Villinger, Francois J.; Veesler, David; King, Neil P.; Suthar, Mehul S.; Khurana, Surender; Baric, Ralph S.; Wilson, Ian A.; Pulendran, Bali 分享 收藏
Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination Adams, Lily E.; Leist, Sarah R.; Dinnon III, Kenneth H.; West, Ande; Gully, Kendra L.; Anderson, Elizabeth J.; Loome, Jennifer F.; Madden, Emily A.; Powers, John M.; Schafer, Alexandra; Sarkar, Sanjay; Castillo, Izabella N.; Maron, Jenny S.; McNamara, Ryan P.; Bertera, Harry L.; Zweigert, Mark R.; Higgins, Jaclyn S.; Hampton, Brea K.; Premkumar, Lakshmanane; Alter, Galit; Montgomery, Stephanie A.; Baxter, Victoria K.; Heise, Mark T.; Baric, Ralph S. 分享 收藏
Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory Mice Amruta, Narayanappa; Ismael, Saifudeen; Leist, Sarah R.; Gressett, Timothy E.; Srivastava, Akhilesh; Dinnon III, Kenneth H.; Engler-Chiurazzi, Elizabeth B.; Maness, Nicholas J.; Qin, Xuebin; Kolls, Jay K.; Baric, Ralph S.; Bix, Gregory 分享 收藏
A C57BL/6 Mouse Model of SARS-CoV-2 Infection Recapitulates Age- and Sex-Based Differences in Human COVID-19 Disease and Recovery Davis, Michael A.; Voss, Kathleen; Turnbull, J. Bryan; Gustin, Andrew T.; Knoll, Megan; Muruato, Antonio; Hsiang, Tien-Ying; Dinnon, Kenneth H.; Leist, Sarah R.; Nickel, Katie; Baric, Ralph S.; Ladiges, Warren; Akilesh, Shreeram; Smith, Kelly D.; Gale, Michael 分享 收藏
IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern Chang, Matthew R.; Tomasovic, Luke; Kuzmina, Natalia A.; Ronk, Adam J.; Byrne, Patrick O.; Johnson, Rebecca; Storm, Nadia; Olmedillas, Eduardo; Hou, Yixuan J.; Schafer, Alexandra; Leist, Sarah R.; Tse, Longping V.; Ke, Hanzhong; Coherd, Christian; Nguyen, Katrina; Kamkaew, Maliwan; Honko, Anna; Zhu, Quan; Alter, Galit; Saphire, Erica Ollmann; McLellan, Jason S.; Griffiths, Anthony; Baric, Ralph S.; Bukreyev, Alexander; Marasco, Wayne A. 分享 收藏
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice Dinnon, Kenneth H., III; Leist, Sarah R.; Okuda, Kenichi; Dang, Hong; Fritch, Ethan J.; Gully, Kendra L.; De la Cruz, Gabriela; Evangelista, Mia D.; Asakura, Takanori; Gilmore, Rodney C.; Hawkins, Padraig; Nakano, Satoko; West, Ande; Schafer, Alexandra; Gralinski, Lisa E.; Everman, Jamie L.; Sajuthi, Satria P.; Zweigart, Mark R.; Dong, Stephanie; McBride, Jennifer; Cooley, Michelle R.; Hines, Jesse B.; Love, Miriya K.; Groshong, Steve D.; VanSchoiack, Alison; Phelan, Stefan J.; Liang, Yan; Hether, Tyler; Leon, Michael; Zumwalt, Ross E.; Barton, Lisa M.; Duval, Eric J.; Mukhopadhyay, Sanjay; Stroberg, Edana; Borczuk, Alain; Thorne, Leigh B.; Sakthivel, Muthu K.; Lee, Yueh Z.; Hagood, James S.; Mock, Jason R.; Seibold, Max A.; O'Neal, Wanda K.; Montgomery, Stephanie A.; Boucher, Richard C.; Baric, Ralph S. 分享 收藏
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