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A

Alice Lepelley

universite paris cite
H指数:22
被引数:7,463

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ATRX deficiency drives aberrant type I interferon signalling through cGAS-dependent transcriptional dysregulation

ATRX缺乏通过cGAS依赖性转录失调驱动异常I型干扰素信号传导

Nature Communications
IF15.7
2026-10-080
OAAI
Marie-Thérèse A. El-Daher; Eve L. White; Andreas Fellas; Graeme Grimes; Simone Pelliciari; Gaofeng Zhu; Tom A. Tait; Carolina Uggenti; Natalie Blair; Erisa Nita; Philippe Gautier; Hywel Dunn-Davies; Sophie Glen; Somdutta Dhir; Mathieu P. Rodero; Gillian I. Rice; Luis Seabra; Richard Clark; Angie Fawkes; Joseph A. Marsh; Minke HW Huibers; Joost B. Koedijk; Erika Van Nieuwenhove; John H. Livingston; Evangeline Wassmer; Swati Naik; Julie Vogt; Bertrand Isidor; Tom D. Deegan; Alice Lepelley; Rebekah Tillotson; Patrick Revy; Richard J. Gibbons; Yanick J. Crow
NAP1 switches from an activator to a limiter of interferon induction by trapping TBK1 in condensates

NAP1通过捕获TBK1在凝聚体中从干扰素诱导的激活剂转变为限制因子

Nature Communications
IF15.7
2026-08-190
OAAI
Damien Glon; Quentin Riller; Lucía Álvarez; Louise Gioja; Frédéric Rivière; Benjamin Léonardon; Zackie Aktary; Ariane Guillemot; Laïla Sago; Olivier Pellé; Nhat-Duong Ho; Karine Brochard; Camille Brunaud; Luís Seabra; Gillian I. Rice; Vincent Bondet; Darragh Duffy; Brigitte Bader-Meunier; Marie-Louise Frémond; Alice Lepelley; Yanick J. Crow; Maud Tusseau; Alexandre Belot; Cécile Lagaudrière-Gesbert; Frédéric Rieux-Laucat; Yves Gaudin
From variant interpretation to structural discovery: A new Zinc-binding domain in PARS2

从变异注释到结构发现：PARS2中一个新的锌结合结构域

Mitochondrion
IF4.5
2026-05-010
OAAI
Hoebeke, Celia; Engel, Camille; Berat, Claire-Marine; Milh, Mathieu; Chaussenot, Annabelle; Boddaert, Nathalie; Chabrol, Brigitte; Saadi, Samira Ait-El-Mkadem; Fragaki, Konstantina; Pereira, Silvia; Lepelley, Alice; Bannwarth, Sylvie; Navarro, Lucile Riera; Paquis-Flucklinger, Veronique; Schiff, Manuel; Sissler, Marie; Rouzier, Cecile
No Correlation Between Interferon Signaling and Cytosolic Mitochondrial DNA/RNA Leakage in Cultured Skin Fibroblasts of Patients With Mitochondrial Diseases

干扰素信号与线粒体疾病患者培养的皮肤成纤维细胞中线粒体DNA/RNA的细胞质泄漏之间无相关性

European Journal of Immunology
IF3.7
2026-04-010
OAAI
Marchais, Manon; Pennisi, Alessandra; Pierga, Alexandre; Lepelley, Alice; Cagnard, Nicolas; Bole, Christine; Nitschke, Patrick; Hamici, Mohamed; Rieux-Laucat, Frederic; Schiff, Manuel; Munnich, Arnold; Rotig, Agnes
Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndrome

药物稳定缺氧诱导因子1-α可减弱干扰素反应并促进Aicardi-Goutières综合征中的糖酵解

Nature Communications
IF15.7
2026-03-030
OA
Maxime Batignes; Marine Luka; Surabhi Jagtap; Camille de Cevins; Ivan Nemazanyy; Jacqueline Leib; Tinhinane Fali; Alexandre Pierga; Mohammed Zarhrate; Víctor García-Paredes; Francesco Carbone; Brieuc P. Pérot; Bénédicte Neven; Brigitte Bader-Meunier; Pierre Quartier; Marie Hully; Alexandre Belot; Alice Lepelley; Marie-Louise Frémond; Alain Fischer; Mickaël M. Ménager
Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus and chilblain lupus
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2024-06-1310
OAAI
David, Clemence; Arango-Franco, Carlos A.; Badonyi, Mihaly; Fouchet, Julien; Rice, Gillian I.; Didry-Barca, Blaise; Maisonneuve, Lucie; Seabra, Luis; Kechiche, Robin; Masson, Cecile; Cobat, Aurelie; Abel, Laurent; Talouarn, Estelle; Beziat, Vivien; Deswarte, Caroline; Livingstone, Katie; Paul, Carle; Malik, Gulshan; Ross, Alison; Adam, Jane; Walsh, Jo; Kumar, Sathish; Bonnet, Damien; Bodemer, Christine; Bader-Meunier, Brigitte; Marsh, Joseph A.; Casanova, Jean-Laurent; Crow, Yanick J.; Manoury, Benedicte; Fremond, Marie-Louise; Bohlen, Jonathan; Lepelley, Alice
Interface Gain-of-Function Mutations in TLR7 Cause Systemic and Neuro-inflammatory Disease
JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2024-02-0711
OAAI
David, Clemence; Badonyi, Mihaly; Kechiche, Robin; Insalaco, Antonella; Zecca, Marco; De Benedetti, Fabrizio; Orcesi, Simona; Chiapparini, Luisa; Comoli, Patrizia; Federici, Silvia; Gattorno, Marco; Ginevrino, Monia; Giorgio, Elisa; Matteo, Valentina; Moran-Alvarez, Patricia; Politano, Davide; Prencipe, Giusi; Sirchia, Fabio; Volpi, Stefano; Masson, Cecile; Rice, Gillian I.; Fremond, Marie-Louise; Lepelley, Alice; Marsh, Joseph A.; Crow, Yanick J.
Heterozygous mutations in the C-terminal domain of COPA underlie a complex autoinflammatory syndrome
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-01-044
OAAI
Delafontaine, Selket; Iannuzzo, Alberto; Bigley, Tarin M.; Mylemans, Bram; Rana, Ruchit; Baatsen, Pieter; Poli, Maria Cecilia; Rymen, Daisy; Jansen, Katrien; Mekahli, Djalila; Casteels, Ingele; Cassiman, Catherine; Demaerel, Philippe; Lepelley, Alice; Fremond, Marie -Louise; Schrijvers, Rik; Bossuyt, Xavier; Vints, Katlijn; Huybrechts, Wim; Tacine, Rachida; Willekens, Karen; Corveleyn, Anniek; Boeckx, Bram; Baggio, Marco; Ehlers, Lisa; Munck, Sebastian; Lambrechts, Diether; Voet, Arnout; Moens, Leen; Bucciol, Giorgia; Cooper, Megan A.; Davis, Carla M.; Delon, Jerome; Meyts, Isabelle
ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling
NATURE COMMUNICATIONS
IF15.7
2023-11-0117
OAAI
Hirschenberger, Maximilian; Lepelley, Alice; Rupp, Ulrich; Klute, Susanne; Hunszinger, Victoria; Koepke, Lennart; Merold, Veronika; Didry-Barca, Blaise; Wondany, Fanny; Bergner, Tim; Moreau, Tatiana; Rodero, Mathieu P.; Roesler, Reinhild; Wiese, Sebastian; Volpi, Stefano; Gattorno, Marco; Papa, Riccardo; Lynch, Sally-Ann; Haug, Marte G.; Houge, Gunnar; Wigby, Kristen M.; Sprague, Jessica; Lenberg, Jerica; Read, Clarissa; Walther, Paul; Michaelis, Jens; Kirchhoff, Frank; Mann, Carina C. de Oliveira; Crow, Yanick J.; Sparrer, Konstantin M. J.
JAK Inhibition in Aicardi-Goutieres Syndrome: a Monocentric Multidisciplinary Real-World Approach Study
JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2023-05-1216
OAAI
Fremond, Marie-Louise; Hully, Marie; Fournier, Benjamin; Barrois, Remi; Levy, Romain; Aubart, Melodie; Castelle, Martin; Chabalier, Delphine; Gins, Clarisse; Sarda, Eugenie; Al Adba, Buthaina; Couderc, Sophie; D' Almeida, Celine; Berat, Claire-Marine; Durrleman, Chloe; Espil, Caroline; Lambert, Laetitia; Meni, Cecile; Perivier, Maximilien; Pillet, Pascal; Polivka, Laura; Schiff, Manuel; Todosi, Calina; Uettwiller, Florence; Lepelley, Alice; Rice, Gillian I.; Seabra, Luis; Sanquer, Sylvia; Hulin, Anne; Pressiat, Claire; Goldwirt, Lauriane; Bondet, Vincent; Duffy, Darragh; Moshous, Despina; Bader-Meunier, Brigitte; Bodemer, Christine; Robin-Renaldo, Florence; Boddaert, Nathalie; Blanche, Stephane; Desguerre, Isabelle; Crow, Yanick J.; Neven, Benedicte
Juvenile Neuropsychiatric Systemic Lupus Erythematosus: Identification of Novel Central Neuroinflammation Biomarkers
JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2022-12-0512
OAAI
Labouret, Mathilde; Costi, Stefania; Bondet, Vincent; Trebossen, Vincent; Le Roux, Enora; Ntorkou, Alexandra; Bartoli, Sophie; Auvin, Stephane; Bader-Meunier, Brigitte; Baudouin, Veronique; Corseri, Olivier; Dingulu, Glory; Ducrocq, Camille; Dumaine, Cecile; Elmaleh, Monique; Fabien, Nicole; Faye, Albert; Hau, Isabelle; Hentgen, Veronique; Kwon, Theresa; Meinzer, Ulrich; Ouldali, Naim; Parmentier, Cyrielle; Pouletty, Marie; Renaldo, Florence; Savioz, Isabelle; Rozenberg, Flore; Fremond, Marie-Louise; Lepelley, Alice; Rice, Gillian I.; Seabra, Luis; Benoist, Jean-Francois; Duffy, Darragh; Crow, Yanick J.; Ellul, Pierre; Melki, Isabelle
Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2021-08-1351
OAAI
Lepelley, Alice; Della Mina, Erika; Van Nieuwenhove, Erika; Waumans, Lise; Fraitag, Sylvie; Rice, Gillian I.; Dhir, Ashish; Fremond, Marie-Louise; Rodero, Mathieu P.; Seabra, Luis; Carter, Edwin; Bodemer, Christine; Buhas, Daniela; Callewaert, Bert; de Lonlay, Pascale; De Somer, Lien; Dyment, David A.; Faes, Fran; Grove, Lucy; Holden, Simon; Hully, Marie; Kurian, Manju A.; McMillan, Hugh J.; Suetens, Kristin; Tyynismaa, Henna; Chhun, Stephanie; Wai, Timothy; Wouters, Carine; Bader-Meunier, Brigitte; Crow, Yanick J.
Differential Expression of Interferon-Alpha Protein Provides Clues to Tissue Specificity Across Type I Interferonopathies
JOURNAL OF CLINICAL IMMUNOLOGY
IF5.7
2021-01-0725
OA
Lodi, Lorenzo; Melki, Isabelle; Bondet, Vincent; Seabra, Luis; Rice, Gillian I.; Carter, Edwin; Lepelley, Alice; Martin-Niclos, Maria Jose; Al Adba, Buthaina; Bader-Meunier, Brigitte; Barth, Magalie; Blauwblomme, Thomas; Bodemer, Christine; Boespflug-Tanguy, Odile; Dale, Russel C.; Desguerre, Isabelle; Ducrocq, Camille; Dulieu, Fabienne; Dumaine, Cecile; Ellul, Pierre; Hadchouel, Alice; Hentgen, Veronique; Hie, Miguel; Hully, Marie; Jeziorski, Eric; Levy, Romain; Mochel, Fanny; Orcesi, Simona; Passemard, Sandrine; Pouletty, Marie; Quartier, Pierre; Renaldo, Florence; Seidl, Rainer; Shetty, Jay; Neven, Benedicte; Blanche, Stephane; Duffy, Darragh; Crow, Yanick J.; Fremond, Marie-Louise
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

由于组蛋白前mRNA加工的先天性错误，cGAS介导的I型干扰素的诱导

NATURE GENETICS
IF31.8
2020-11-23121
OAAI
Uggenti, Carolina; Lepelley, Alice; Depp, Marine; Badrock, Andrew P.; Rodero, Mathieu P.; El-Daher, Marie-Therese; Rice, Gillian I.; Dhir, Somdutta; Wheeler, Ann P.; Dhir, Ashish; Albawardi, Waad; Fremond, Marie-Louise; Seabra, Luis; Doig, Jennifer; Blair, Natalie; Martin-Niclos, Maria Jose; Della Mina, Erika; Rubio-Roldan, Alejandro; Garcia-Perez, Jose L.; Sproul, Duncan; Rehwinkel, Jan; Hertzog, Jonny; Boland-Auge, Anne; Olaso, Robert; Deleuze, Jean-Francois; Baruteau, Julien; Brochard, Karine; Buckley, Jonathan; Cavallera, Vanessa; Cereda, Cristina; De Waele, Liesbeth M. H.; Dobbie, Angus; Doummar, Diane; Elmslie, Frances; Koch-Hogrebe, Margarete; Kumar, Ram; Lamb, Kate; Livingston, John H.; Majumdar, Anirban; Lorenco, Charles Marques; Orcesi, Simona; Peudenier, Sylviane; Rostasy, Kevin; Salmon, Caroline A.; Scott, Christiaan; Tonduti, Davide; Touati, Guy; Valente, Marialuisa; van der Linden, Helio, Jr.; Van Esch, Hilde; Vermelle, Marie; Webb, Kate; Jackson, Andrew P.; Reijns, Martin A. M.; Gilbert, Nick; Crow, Yanick J.
Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2020-07-28142
OAAI
Lepelley, Alice; Martin-Niclos, Maria Jose; Le Bihan, Melvin; Marsh, Joseph A.; Uggenti, Carolina; Rice, Gillian, I; Bondet, Vincent; Duffy, Darragh; Hertzog, Jonny; Rehwinkel, Jan; Amselem, Serge; Boulisfane-El Khalifi, Siham; Brennan, Mary; Carter, Edwin; Chatenoud, Lucienne; Chhun, Stephanie; l'Hermine, Aurore Coulomb; Depp, Marine; Legendre, Marie; Mackenzie, Karen J.; Marey, Jonathan; McDougall, Catherine; McKenzie, Kathryn J.; Molina, Thierry Jo; Neven, Benedicte; Seabra, Luis; Thumerelle, Caroline; Wislez, Marie; Nathan, Nadia; Manel, Nicolas; Crow, Yanick J.; Fremond, Marie-Louise
Reverse-Transcriptase Inhibitors in the Aicardi-Goutieres Syndrome
NEW ENGLAND JOURNAL OF MEDICINE
IF78.5
2018-12-06116
OAAI
Rice, Gillian I.; Meyzer, Candice; Bouazza, Naim; Hully, Marie; Boddaert, Nathalie; Semeraro, Michaela; Zeef, Leo A. H.; Rozenberg, Flore; Bondet, Vincent; Duffy, Darragh; Llibre, Alba; Baek, Jinmi; Sambe, Mame N.; Henry, Elodie; Jolaine, Valerie; Barnerias, Christine; Barth, Magalie; Belot, Alexandre; Cances, Claude; Debray, Francois-Guillaume; Doummar, Diane; Fremond, Marie-Louise; Kitabayashi, Naoki; Lepelley, Alice; Levrat, Virginie; Melki, Isabelle; Meyer, Pierre; Nougues, Marie-Christine; Renaldo, Florence; Rodero, Mathieu P.; Rodriguez, Diana; Roubertie, Agathe; Seabra, Luis; Uggenti, Carolina; Abdoul, Hendy; Treluyer, Jean-Marc; Desguerre, Isabelle; Blanche, Stephane; Crow, Yanick J.

研究方向

暂未获取到该数据
Y
Yanick J. Crow
H 指数:91论文数:430被引数:3.1万
M
Marie‐Louise Frémond
H 指数:33论文数:119被引数:4,140
G
Gillian Rice
H 指数:64论文数:311被引数:1.8万
L
Luís Seabra
H 指数:20论文数:41被引数:1,655
D
Darragh Duffy
H 指数:62论文数:361被引数:2.4万
V
Vincent Bondet
H 指数:35论文数:135被引数:8,734
B
Brigitte Bader‐Meunier
H 指数:72论文数:527被引数:1.8万
O
Olivier Schwartz
H 指数:100论文数:497被引数:4.6万
J
Joseph A. Marsh
H 指数:47论文数:207被引数:8,683
C
Christine Bodemer
H 指数:73论文数:627被引数:2.4万