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H

Helmut Grasberger

university of michigan system
H指数:34
被引数:4,096

个人简介

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教育背景

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工作经历

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荣誉奖项

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IL-15 Promotes Inflammatory Th17 Cells in the Intestine

IL-15 促进肠道炎症性Th17细胞

INFLAMMATORY BOWEL DISEASES
IF4.3
2025-11-010
PRE
Hou, Guoqing; Lee, Allen; Golob, Jonathan L.; Grasberger, Helmut; Berinstein, Elliott; Swanson, Benjamin J.; Bishu, Shreenath R.; El Zataari, Mohamed; Khaykin, Valerie; Berinstein, Jeff A.; Fry, Christopher; Nemzek, Jean; Kamada, Nobuhiko; Kao, John; Bishu, Shrinivas
STR mutations on chromosome 15q cause thyrotropin resistance by activating a primate-specific enhancer of MIR7-2/MIR1179
NATURE GENETICS
IF31.8
2024-05-073
PRE
Grasberger, Helmut; Dumitrescu, Alexandra M.; Liao, Xiao-Hui; Swanson, Elliott G.; Weiss, Roy E.; Srichomkwun, Panudda; Pappa, Theodora; Chen, Junfeng; Yoshimura, Takashi; Hoffmann, Phillip; Franca, Monica Malheiros; Tagett, Rebecca; Onigata, Kazumichi; Costagliola, Sabine; Ranchalis, Jane; Vollger, Mitchell R.; Stergachis, Andrew B.; Chong, Jessica X.; Bamshad, Michael J.; Smits, Guillaume; Vassart, Gilbert; Refetoff, Samuel
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

肠上皮内质网应激启动嘌呤代谢产物合成并促进Th17细胞分化

IMMUNITY
IF26.3
2023-05-0129
OAAI
Duan, Jinzhi; Matute, Juan D.; Unger, Lukas W.; Hanley, Thomas; Schnell, Alexandra; Lin, Xi; Krupka, Niklas; Griebel, Paul; Lambden, Conner; Sit, Brandon; Grootjans, Joep; Pyzik, Michal; Sommer, Felix; Kaiser, Sina; Falk-Paulsen, Maren; Grasberger, Helmut; Kao, John Y.; Fuhrer, Tobias; Li, Hai; Paik, Donggi; Lee, Yunjin; Refetoff, Samuel; Glickman, Jonathan N.; Paton, Adrienne W.; Bry, Lynn; Paton, James C.; Sauer, Uwe; Macpherson, Andrew J.; Rosenstiel, Philip; Kuchroo, Vijay K.; Waldor, Matthew K.; Huh, Jun R.; Kaser, Arthur; Blumberg, Richard S.
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation
SCIENCE SIGNALING
IF6.6
2021-11-1634
OA
Gu, Feng; Krueger, Aileen; Roggenkamp, Hannes G.; Alpers, Rick; Lodygin, Dmitri; Jaquet, Vincent; Moeckl, Franziska; Hernandez, Lola C. C.; Winterberg, Kai; Bauche, Andreas; Rosche, Anette; Grasberger, Helmut; Kao, John Y.; Schetelig, Daniel; Werner, Rene; Schroeder, Katrin; Carty, Michael; Bowie, Andrew G.; Huber, Samuel; Meier, Chris; Mittruecker, Hans-Willi; Heeren, Joerg; Krause, Karl-Heinz; Fluegel, Alexander; Diercks, Bjoern-Philipp; Guse, Andreas H.
DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-05-0335
OA
Grasberger, Helmut; Magis, Andrew T.; Sheng, Elisa; Conomos, Matthew P.; Zhang, Min; Garzotto, Lea S.; Hou, Guoqing; Bishu, Shrinivas; Nagao-Kitamoto, Hiroko; El-Zaatari, Mohamad; Kitamoto, Sho; Kamada, Nobuhiko; Stidham, Ryan W.; Akiba, Yasutada; Kaunitz, Jonathan; Haberman, Yael; Kugathasan, Subra; Denson, Lee A.; Omenn, Gilbert S.; Kao, John Y.
CD4+ Tissue-resident Memory T Cells Expand and Are a Major Source of Mucosal Tumour Necrosis Factor α in Active Crohn's Disease

CD4组织驻留记忆T细胞扩增，是活动性克罗恩病中粘膜肿瘤坏死因子 α 的主要来源

JOURNAL OF CROHNS & COLITIS
IF8.7
2019-02-0443
OAAI
Bishu, Shrinivas; El Zaatari, Mohammed; Hayashi, Atsushi; Hou, Guoqing; Bowers, Nicole; Kinnucan, Jami; Manoogian, Beth; Muza-Moons, Michelle; Zhang, Min; Grasberger, Helmut; Bourque, Charlie; Zou, Weiping; Higgins, Peter D. R.; Spence, Jason R.; Stidham, Ryan W.; Kamada, Nobuhiko; Kao, John Y.

研究方向

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S
Samuel Refetoff
H 指数:94论文数:706被引数:3.0万
J
John Y. Kao
H 指数:61论文数:293被引数:1.3万
M
Mohamad El‐Zaatari
H 指数:27论文数:87被引数:2,611
N
Nobuhiko Kamada
H 指数:69论文数:217被引数:2.2万
S
Shrinivas Bishu
H 指数:33论文数:175被引数:3,752
O
Onno E. Janßen
H 指数:44论文数:157被引数:1.1万
张
张敏
H 指数:37论文数:211被引数:4,888
R
Roy E. Weiss
H 指数:62论文数:269被引数:1.1万
A
Andrew B. Shreiner
H 指数:16论文数:40被引数:3,144
M
Marília Cascalho
H 指数:40论文数:194被引数:8,935