J. Wade Davis

AbbVie

H指数:38

被引数:8,450

个人简介

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工作经历

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荣誉奖项

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Progression GWAS followed by functional characterization implicates E3 ubiquitin ligase TRIM2 as a potential genetic modifier of Parkinson’s disease progression

进展性全基因组关联研究结合功能表征表明E3泛素连接酶TRIM2可能是帕金森病进展的潜在遗传修饰因子

Scientific Reports

IF3.9

2026-09-020

OAAI

A Pharmacophore-Based Method for Rapid and Accurate Virtual Screening of Antibody Libraries against Antigens

基于药效团的抗体库对抗原进行快速准确的虚拟筛选方法

Molecular Pharmaceutics

IF4.5

2025-07-220

Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease

ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING

IF4.4

2022-09-2011

Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes

CELL GENOMICS

IF9

2022-09-0191

OAAI

Karczewski, Konrad J.; Solomonson, Matthew; Chao, Katherine R.; Goodrich, Julia K.; Tiao, Grace; Lu, Wenhan; Riley-Gillis, Bridget M.; Tsai, Ellen A.; Kim, Hye In; Zheng, Xiuwen; Rahimov, Fedik; Esmaeeli, Sahar; Grundstad, A. Jason; Reppell, Mark; Waring, Jeff; Jacob, Howard; Sexton, David; Bronson, Paola G.; Chen, Xing; Hu, Xinli; Goldstein, Jacqueline I.; King, Daniel; Vittal, Christopher; Poterba, Timothy; Palmer, Duncan S.; Churchhouse, Claire; Howrigan, Daniel P.; Zhou, Wei; Watts, Nicholas A.; Nguyen, Kevin; Nguyen, Huy; Mason, Cara; Farnham, Christopher; Tolonen, Charlotte; Gauthier, Laura D.; Gupta, Namrata; MacArthur, Daniel G.; Rehm, Heidi L.; Seed, Cotton; Philippakis, Anthony A.; Daly, Mark J.; Davis, J. Wade; Runz, Heiko; Miller, Melissa R.; Neale, Benjamin M.

The SEQC2 epigenomics quality control (EpiQC) study (vol 22, 332, 2021)

GENOME BIOLOGY

IF9.4

2021-12-230

OAAI

Foox, Jonathan; Nordlund, Jessica; Lalancette, Claudia; Gong, Ting; Lacey, Michelle; Lent, Samantha; Langhorst, Bradley W.; Ponnaluri, V. K. Chaithanya; Williams, Louise; Padmanabhan, Karthik Ramaswamy; Cavalcante, Raymond; Lundmark, Anders; Butler, Daniel; Mozsary, Christopher; Gurvitch, Justin; Greally, John M.; Suzuki, Masako; Menor, Mark; Nasu, Masaki; Alonso, Alicia; Sheridan, Caroline; Scherer, Andreas; Bruinsma, Stephen; Golda, Gosia; Muszynska, Agata; Labaj, Pawel P.; Campbell, Matthew A.; Wos, Frank; Raine, Amanda; Liljedahl, Ulrika; Axelsson, Tomas; Wang, Charles; Chen, Zhong; Yang, Zhaowei; Li, Jing; Yang, Xiaopeng; Wang, Hongwei; Melnick, Ari; Guo, Shang; Blume, Alexander; Franke, Vedran; de Caceres, Inmaculada Ibanez; Rodriguez-Antolin, Carlos; Rosas, Rocio; Davis, Justin Wade; Ishii, Jennifer; Megherbi, Dalila B.; Xiao, Wenming; Liao, Will; Xu, Joshua; Hong, Huixiao; Ning, Baitang; Tong, Weida; Akalin, Altuna; Wang, Yunliang; Deng, Youping; Mason, Christopher E.

The SEQC2 epigenomics quality control (EpiQC) study

GENOME BIOLOGY

IF9.4

2021-12-0619

OAAI

Foox, Jonathan; Nordlund, Jessica; Lalancette, Claudia; Gong, Ting; Lacey, Michelle; Lent, Samantha; Langhorst, Bradley W.; Ponnaluri, V. K. Chaithanya; Williams, Louise; Padmanabhan, Karthik Ramaswamy; Cavalcante, Raymond; Lundmark, Anders; Butler, Daniel; Mozsary, Christopher; Gurvitch, Justin; Greally, John M.; Suzuki, Masako; Menor, Mark; Nasu, Masaki; Alonso, Alicia; Sheridan, Caroline; Scherer, Andreas; Bruinsma, Stephen; Golda, Gosia; Muszynska, Agata; Labaj, Pawel P.; Campbell, Matthew A.; Wos, Frank; Raine, Amanda; Liljedahl, Ulrika; Axelsson, Tomas; Wang, Charles; Chen, Zhong; Yang, Zhaowei; Li, Jing; Yang, Xiaopeng; Wang, Hongwei; Melnick, Ari; Guo, Shang; Blume, Alexander; Franke, Vedran; Ibanez de Caceres, Inmaculada; Rodriguez-Antolin, Carlos; Rosas, Rocio; Davis, Justin Wade; Ishii, Jennifer; Megherbi, Dalila B.; Xiao, Wenming; Liao, Will; Xu, Joshua; Hong, Huixiao; Ning, Baitang; Tong, Weida; Akalin, Altuna; Wang, Yunliang; Deng, Youping; Mason, Christopher E.

Association of peripheral blood DNA methylation level with Alzheimer's disease progression

CLINICAL EPIGENETICS

IF4.4

2021-10-1535

OAAI

Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

通过英国生物库的外显子组测序推进人类遗传学研究和药物发现

NATURE GENETICS

IF31.8

2021-06-28194

OAAI

Szustakowski, Joseph D.; Balasubramanian, Suganthi; Kvikstad, Erika; Khalid, Shareef; Bronson, Paola G.; Sasson, Ariella; Wong, Emily; Liu, Daren; Wade Davis, J.; Haefliger, Carolina; Katrina Loomis, A.; Mikkilineni, Rajesh; Noh, Hyun Ji; Wadhawan, Samir; Bai, Xiaodong; Hawes, Alicia; Krasheninina, Olga; Ulloa, Ricardo; Lopez, Alex E.; Smith, Erin N.; Waring, Jeffrey F.; Whelan, Christopher D.; Tsai, Ellen A.; Overton, John D.; Salerno, William J.; Jacob, Howard; Szalma, Sandor; Runz, Heiko; Hinkle, Gregory; Nioi, Paul; Petrovski, Slave; Miller, Melissa R.; Baras, Aris; Mitnaul, Lyndon J.; Reid, Jeffrey G.

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

CLINICAL EPIGENETICS

IF4.4

2020-06-1553

OAAI

A Genetic Variant in the BCL2 Gene Associates with Adalimumab Response in Hidradenitis Suppurativa Clinical Trials and Regulates Expression of BCL2

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2020-03-0116

OAAI

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval

PLOS GENETICS