Brian Gabrielli - Publications, H-index & Citations

Brian Gabrielli

the university of queensland

52H指数

241论文数

7.7K被引数

收录论文 95

发表时间

S-phase targeted treatment triggers caspase-dependent lytic immunogenic cell death with pyroptotic features in cancers S期靶向治疗在癌症中触发具有焦亡特征的半胱天冬酶依赖性裂解性免疫原性细胞死亡

Cell Death and Differentiation

IF15.4

2026-07-10

OAAI

Rituparna Bhatt; Si En Ong; Dan A. Erkes; Katia Maria Xavier Leung; Koyo Kinase; Khai Yee Lim; Alexis Bonfim-Melo; Enaam Alghamdi; Sheena Daignault-Mill; Yoon Lim; Nur Jannah Abdul Rahim; Aditya Gopalakrishnan; Xin Yee Ong; Nicole Lisa Li-Ann Goh; Anastasia Gandini; Martina Proctor; Sharad Kumar; Zhen Zeng; Nikolas K. Haass; Mathew JK Jones; Paul Clarke; Andrew E. Aplin; Brian Gabrielli

Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer 采用靶向疗法促进高级别浆液性卵巢癌的促炎肿瘤微环境及抗肿瘤免疫反应

British Journal of Cancer

IF6.8

2026-04-07

OAAI

Zhen Zeng; Anastasia Gandini; Rituparna Bhatt; Martina Proctor; Nicole-Lisa Li-Ann Goh; Shivam Vora; Thomas P. Walsh; Sherry Y. Wu; Kaltin Ferguson; Jermaine I. Coward; Snehlata Kumari; Nikolas K. Haass; James W. Wells; Janet Hardy; Lewis Perrin; Yaowu He; John D. Hooper; Gwo-Yaw Ho; Jazmina L. Gonzalez Cruz; Brian Gabrielli

Tetraploids or polyploid giants: who is truly dangerous?四倍体或多倍体巨体：谁才是真正的危险？

Trends in Cell Biology

IF18.1

2026-03-28

OAAI

Mathew Bloomfield; Shivam Vora; Dinethra Epa; Brian Gabrielli; Daniela Cimini

Aurora B inhibition induces hyper-polyploidy and loss of long-term proliferative potential in RB and p53 defective cells

CELL DEATH & DISEASE

IF9.6

2025-01-08

OAAI

Vora, Shivam; Chatterjee, Saptarshi; Andrew, Ariel; Kumar, Ramyashree Prasanna; Proctor, Martina; Zeng, Zhen; Bhatt, Rituparna; Nazareth, Deborah; Fernando, Madushan; Jones, Mathew J. K.; He, Yaowu; Hooper, John D.; Mcmillan, Nigel A. J.; Urosevic, Jelena; Saeh, Jamal; Travers, Jon; Cimini, Daniela; Chen, Jing; Gabrielli, Brian

Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition Aurora B抑制剂促进RB低磷酸化和衰老，而与p53-dependent CDK2/4抑制无关

CELL DEATH & DISEASE

IF9.6

2024-11-09

OAAI

Vora, Shivam; Andrew, Ariel; Kumar, Ramyashree Prasanna; Nazareth, Deborah; Bonfim-Melo, Alexis; Lim, Yoon; Ong, Xin Yee; Fernando, Madushan; He, Yaowu; Hooper, John D.; McMillan, Nigel A. J.; Urosevic, Jelena; Travers, Jon; Saeh, Jamal; Kumar, Sharad; Jones, Mathew J. K.; Gabrielli, Brian

Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells 抑制Aurora B激酶 (AURKB) 增强5-氟尿嘧啶化疗对结直肠癌细胞的有效性

BRITISH JOURNAL OF CANCER

IF6.8

2024-01-29

OAAI

Shah, Esha T.; Molloy, Christopher; Gough, Madeline; Kryza, Thomas; Samuel, Selwin G.; Tucker, Amos; Bhatia, Maneet; Ferguson, Genevieve; Heyman, Rebecca; Vora, Shivam; Monkman, James; Bolderson, Emma; Kulasinghe, Arutha; He, Yaowu; Gabrielli, Brian; Hooper, John D.; Richard, Derek J.; O'Byrne, Kenneth J.; Adams, Mark N.

Checkpoint kinase 1 inhibitor? plus ?low-dose hydroxyurea efficiently kills BRAF inhibitor- and immune checkpoint inhibitor-resistant melanomas

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2023-08-23

OAAI

Zeng, Zhen; Ngo, Hung Long; Proctor, Martina; Rizos, Helen; Dolcetti, Riccardo; Cruz, Jazmina Gonzalez; Wells, James W.; Gabrielli, Brian

CtBPs Promote Cell Survival through the Maintenance of Mitotic Fidelity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Bergman, Lee M.; Birts, Charles N.; Darley, Matthew; Gabrielli, Brian; Blaydes, Jeremy P.

Dysregulated G2 phase checkpoint recovery pathway reduces DNA repair efficiency and increases chromosomal instability in a wide range of tumours

ONCOGENESIS

IF6.4

2021-05-15

OAAI

Fernando, Madushan; Duijf, Pascal H. G.; Proctor, Martina; Stevenson, Alexander J.; Ehmann, Anna; Vora, Shivam; Skalamera, Dubravka; Adams, Mark; Gabrielli, Brian

Unexpected High Levels of BRN2/POU3F2 Expression in Human Dermal Melanocytic Nevi

JOURNAL OF INVESTIGATIVE DERMATOLOGY

IF5.7

2020-06-01

OAAI

Chitsazan, Arash; Lambie, Duncan; Ferguson, Blake; Handoko, Herlina Y.; Gabrielli, Brian; Walker, Graeme J.; Boyle, Glen M.

Multiple interaction nodes define the postreplication repair response to UV-induced DNA damage that is defective in melanomas and correlated with UV signature mutation load

MOLECULAR ONCOLOGY

IF4.5

2019-12-19

OAAI

Pavey, Sandra; Pinder, Alex; Fernando, Winnie; D'Arcy, Nicholas; Matigian, Nicholas; Skalamera, Dubravka; Le Cao, Kim-Anh; Loo-Oey, Dorothy; Hill, Michelle M.; Stark, Mitchell; Kimlin, Michael; Burgess, Andrew; Cloonan, Nicole; Sturm, Richard A.; Gabrielli, Brian

Melanoma mutations modify melanocyte dynamics in co-culture with keratinocytes or fibroblasts

JOURNAL OF CELL SCIENCE

IF3.6

2019-12-13

OAAI

Skalamera, Dubravka; Stevenson, Alexander J.; Ehmann, Anna; Ainger, Stephen A.; Lanagan, Catherine; Sturm, Richard A.; Gabrielli, Brian

Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress

MOLECULAR CANCER THERAPEUTICS

IF5.5

2019-12-01

PREAI

Andrews, Ariel; Kumar, Ramyashree Prasanna; Nazareth, Deborah; Ehmann, Anna; Hooper, John; McMillan, Nigel; Gabrielli, Brian

Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Oo, Zay Yar; Proctor, Martina; Stevenson, Alex; Nazareth, Deborah; Larsen, Jill; Haass, Nikolas; Gabrielli, Brian G.

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

MOLECULAR ONCOLOGY

IF4.5

2019-06-14

OAAI

Oo, Zay Yar; Proctor, Martina; Stevenson, Alexander J.; Nazareth, Deborah; Fernando, Madushan; Daignault, Sheena M.; Lanagan, Catherine; Walpole, Sebastian; Bonazzi, Vanessa; Skalamera, Dubravka; Snell, Cameron; Haass, Nikolas K.; Larsen, Jill E.; Gabrielli, Brian

Aurora kinases are a novel therapeutic target for HPV-positive head and neck cancers Aurora激酶是HPV阳性头颈癌的新治疗靶点

ORAL ONCOLOGY

IF3.9

2018-11-01

PREAI

Shaikh, Mushfiq H.; Idris, Adi; Johnson, Newell W.; Fallaha, Sora; Clarke, Daniel T. W.; Martin, David; Morgan, Iain M.; Gabrielli, Brian; McMillan, Nigel A. J.

Pathway dysregulation analysis of the nucleotide excision repair mechanisms reveals it is not a common feature of melanomas

PIGMENT CELL & MELANOMA RESEARCH

IF2.6

2018-10-22

OAAI

D'Arcy, Nicholas; Matigian, Nicholas; Cao, Kim-Anh Le; Gabrielli, Brian

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer

EMBO MOLECULAR MEDICINE

IF8.3

2018-08-14

OAAI

Kalimutho, Murugan; Sinha, Debottam; Jeffery, Jessie; Nones, Katia; Srihari, Sriganesh; Fernando, Winnie C.; Duijf, Pascal H. G.; Vennin, Claire; Raninga, Prahlad; Nanayakkara, Devathri; Mittal, Deepak; Saunus, Jodi M.; Lakhani, Sunil R.; Lopez, J. Alejandro; Spring, Kevin J.; Timpson, Paul; Gabrielli, Brian; Waddell, Nicola; Khanna, Kum Kum

Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo

CLINICAL CANCER RESEARCH

IF10.2

2018-06-14

OAAI

Oo, Zay Yar; Stevenson, Alexander J.; Proctor, Martina; Daignault, Sheena M.; Walpole, Sebastian; Lanaganl, Catherine; Chen, James; Skalamera, Dubravka; Spoerri, Loredana; Ainger, Stephen A.; Sturm, Richard A.; Haass, Nikolas K.; Gabrielli, Brian

Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells

CELL CYCLE

IF3.4

2018-04-25

OAAI

Levrier, Claire; Rockstroh, Anja; Gabrielli, Brian; Kavallaris, Maria; Lehman, Melanie; Davis, Rohan A.; Sadowski, Martin C.; Nelson, Colleen C.

研究方向