Kenneth Wu

Gladstone Institute of Cardiovascular Disease

H指数:27

被引数:3,922

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A microphysiological system for screening lipid nanoparticle−mRNA complexes predicts in vivo heart transfection efficacy

一种微生理系统用于筛选脂质纳米颗粒−mRNA复合物，可预测体内心脏转染效率

Nature Biomedical Engineering

IF26.6

2025-11-030

PRE

COMET enables direct screening for interactions between E3 ubiquitin ligases and their proteolytic target proteins

COMET能够直接筛选E3泛素连接酶与其蛋白水解底物蛋白之间的相互作用。

MOLECULAR CELL

IF16.6

2025-02-010

PRE

Modulation of Cullin-RING E3 ubiquitin ligase-dependent ubiquitination by small molecule compounds

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-011

OAAI

Monoubiquitination empowers ubiquitin chain elongation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-03-010

OAAI

CRL4b Inhibition Ameliorates Experimental Autoimmune Encephalomyelitis Progression

JOURNAL OF IMMUNOLOGY

IF3.4

2024-01-241

PRE

Functional analysis of a common BAG3 allele associated with protection from heart failure

cardiovascular research

IF10.8

2023-06-263

The SCFHOS/β-TRCP-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28112

OAAI

Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2740

OAAI

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential

具有抗肿瘤潜力的cullin环E3泛素连接酶4的抑制剂

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-02-1814

OAAI

A new FRET-based platform to track substrate ubiquitination by fluorescence

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-016

OAAI

IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5

JOURNAL OF PROTEOME RESEARCH

IF3.6

2020-01-177

Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes

NATURE GENETICS

IF31.8

2019-07-31135

OAAI

SCFFBXO22 targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-05-2837

OAAI

Suramin inhibits cullin-RING E3 ubiquitin ligases

苏拉明抑制cullin-ring E3泛素连接酶

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-03-2146

OAAI

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination

泛素Y59-E51环在赖氨酸48聚泛素化中的关键作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-05-2732

OAAI

A SnapShot of Ubiquitin Chain Elongation LYSINE 48-TETRA-UBIQUITIN SLOWS DOWN UBIQUITINATION

泛素链延长赖氨酸48-四泛素的快照减慢泛素化

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-03-018

OAAI

Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-05-0152

OAAI

Mono-ubiquitination Drives Nuclear Export of the Human DCN1-like Protein hDCNL1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-09-0128

OAAI

Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of Unfolded Cytosolic Proteins

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2010-07-01134

OAAI

The Human Cdc34 Carboxyl Terminus Contains a Non-covalent Ubiquitin Binding Activity That Contributes to SCF-dependent Ubiquitination

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-06-0124

OAAI

Kenneth Wu

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