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D

Donald E. Spratt

Clark University

H指数:20

被引数:1,663

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Conserved IQ motifs, divergent apo-calmodulin recognition in UBE3B and UBE3C

保守的IQ基序，UBE3B和UBE3C中apo-钙调素识别的差异

Protein Science

IF5.2

2026-10-240

OAAI

Best practices for isothermal titration calorimetry of protein–DNA interactions

蛋白质-核酸相互作用等温滴定量热法的最佳实践

Analytical Biochemistry

IF2.5

2026-09-070

PRE

Structural modification of the propyl linker of cjoc42 in combination with sulfonate ester and triazole replacements for enhanced gankyrin binding and anti-proliferative activity

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2024-08-010

PRE

Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders

FUTURE MEDICINAL CHEMISTRY

IF3.4

2024-01-110

PRE

Exchange Broadening Underlies the Enhancement of IDE-Dependent Degradation of Insulin by Anionic Membranes

IF4.3

2022-07-072

OAAI

Small-Molecule Gankyrin Inhibition as a Therapeutic Strategy for Breast and Lung Cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-06-277

OA

Extending the Catalytic HECT Domain Boundaries for the HECT E3 Ubiquitin Ligase HACE1 Increases Solubility and Enzymatic Activity

IF4.2

2022-05-130

PRE

Differential Effects of Polyphenols on Insulin Proteolysis by the Insulin-Degrading Enzyme

IF6.6

2021-08-256

OAAI

Intersection of Redox Chemistry and Ubiquitylation: Post-Translational Modifications Required for Maintaining Cellular Homeostasis and Neuroprotection

IF5.2

2021-08-182

OAAI

HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response

IF3.5

2021-06-0943

OAAI

Exploring the Roles of HERC2 and the NEDD4L HECT E3 Ubiquitin Ligase Subfamily in p53 Signaling and the DNA Damage Response

FRONTIERS IN ONCOLOGY

IF3.3

2021-03-3114

OAAI

HECT E3 ubiquitin ligases - emerging insights into their biological roles and disease relevance (vol 133, jcs228072, 2020)

JOURNAL OF CELL SCIENCE

IF3.6

2020-12-213

OA

Lysine 33 polyubiquitin chain formation by the HECT Ubiquitin E3 Ligase AREL1

IF4.2

2020-04-200

PRE

Structural and Mechanistic Characterization of HERC2 E3 Ubiquitin Ligase C-lobe with Implications in Cancer, Prader-Willi Syndrome, and Eye Color

IF4.2

2020-04-200

PRE

HECT E3 ubiquitin ligases - emerging insights into their biological roles and disease relevance

HECT E3泛素连接酶-对其生物学作用和疾病相关性的新见解

JOURNAL OF CELL SCIENCE

IF3.6

2020-04-07112

OA

A subset of calcium-binding S100 proteins show preferential heterodimerization

IF4.2

2019-02-2117

OAAI

Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme

BIOSCIENCE REPORTS

IF4.7

2018-11-0712

OAAI

Resveratrol Sustains Insulin-Degrading Enzyme Activity toward Aβ42

IF4.3

2018-10-1621

OAAI

The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme

ACS CHEMICAL NEUROSCIENCE

IF3.9

2018-08-017

OAAI

Generation of phospho-ubiquitin variants by orthogonal translation reveals codon skipping

IF3

2016-05-0437

PREAI