未登录 Jumonji histone demethylases are therapeutic targets in small cell lung cancer Nguyen, Aiden; Nunez, Clarissa G.; Tran, Tram Anh; Girard, Luc; Peyton, Michael; Catalan, Rodrigo; Guerena, Cristina; Avila, Kimberley; Drapkin, Benjamin J.; Chandra, Raghav; Minna, John D.; Martinez, Elisabeth D. 分享 收藏
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In vivo CRISPR screen identifies SOAT1 as a chemotherapy chemosensitizing target for non-small cell lung cancer (NSCLC) Li, Long Shan; Huffman, Kenneth; Li, Huiyu; Peyton, Michael; Park, Hyunsil; Avila, Kimberley; Girard, Luc; Augustine, Mathew; Mendell, Joshua T.; Minna, John D. 分享 收藏
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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells Li, Huiyu; Liu, Zhida; Liu, Longchao; Zhang, Hongyi; Han, Chuanhui; Girard, Luc; Park, Hyunsil; Zhang, Anli; Dong, Chunbo; Ye, Jianfeng; Rayford, Austin; Peyton, Michael; Li, Xiaoguang; Avila, Kimberley; Cao, Xuezhi; Hu, Shuiqing; Alam, Md Maksudul; Akbay, Esra A.; Solis, Luisa M.; Behrens, Carmen; Hernandez-Ruiz, Sharia; Lu, Wei; Wistuba, Ignacio; Heymach, John, V; Chisamore, Michael; Micklem, David; Gabra, Hani; Gausdal, Gro; Lorens, James B.; Li, Bo; Fu, Yang-Xin; Minna, John D.; Brekken, Rolf A. 分享 收藏
Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations Yenerall, Paul; Kollipara, Rahul K.; Avila, Kimberley; Peyton, Michael; Eide, Christopher A.; Bottomly, Daniel; McWeeney, Shannon K.; Liu, Yan; Westover, Kenneth D.; Druker, Brian J.; Minna, John D.; Kittler, Ralf 分享 收藏
An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis Hight, Suzie K.; Mootz, Allison; Kollipara, Rahul K.; McMillan, Elizabeth; Yenerall, Paul; Otaki, Yoichi; Li, Long-Shan; Avila, Kimberley; Peyton, Michael; Rodriguez-Canales, Jaime; Mino, Barbara; Villalobos, Pamela; Girard, Luc; Dospoy, Patrick; Larsen, Jill; White, Michael A.; Heymach, John V.; Wistuba, Ignacio I.; Kittler, Ralf; Minna, John D. 分享 收藏
eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer Suresh, Shruthy; Chen, BeiBei; Zhu, Jingfei; Golden, Ryan J.; Lu, Changzheng; Evers, Bret M.; Novaresi, Nicole; Smith, Bethany; Zhan, Xiaowei; Schmid, Vanessa; Jun, Sojeong; Karacz, Chelsea M.; Peyton, Michael; Zhong, Lin; Wen, Zhuoyu; Sathe, Adwait Amod; Xing, Chao; Behrens, Carmen; Wistuba, Ignacio I.; Xiao, Guanghua; Xie, Yang; Fu, Yang-Xin; Minna, John D.; Mendell, Joshua T.; O'Donnell, Kathryn A. 分享 收藏
EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer Gong, Ke; Guo, Gao; Panchani, Nishah; Bender, Matthew E.; Gerber, David E.; Minna, John D.; Fattah, Farjana; Gao, Boning; Peyton, Michael; Kernstine, Kemp; Mukherjee, Bipasha; Burma, Sandeep; Chiang, Cheng-Ming; Zhang, Shanrong; Amod Sathe, Adwait; Xing, Chao; Dao, Kathryn H.; Zhao, Dawen; Akbay, Esra A.; Habib, Amyn A. 分享 收藏
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Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells Chen, Pei-Hsuan; Cai, Ling; Huffman, Kenneth; Yang, Chendong; Kim, Jiyeon; Faubert, Brandon; Boroughs, Lindsey; Ko, Bookyung; Sudderth, Jessica; McMillan, Elizabeth A.; Girard, Luc; Chen, Dong; Peyton, Michael; Shields, Misty D.; Yao, Bo; Shames, David S.; Kim, Hyun Seok; Timmons, Brenda; Sekine, Ikuo; Britt, Rebecca; Weber, Stephanie; Byers, Lauren A.; Heymach, John V.; Chen, Jing; White, Michael A.; Minna, John D.; Xiao, Guanghua; DeBerardinis, Ralph J. 分享 收藏
Telomerase-Mediated Strategy for Overcoming Non-Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance Mender, Igen; LaRanger, Ryan; Luitel, Krishna; Peyton, Michael; Girard, Luc; Lai, Tsung-Po; Batten, Kimberly; Cornelius, Crystal; Dalvi, Maithili P.; Ramirez, Michael; Du, Wenting; Wu, Lani F.; Altschuler, Steven J.; Brekken, Ron; Martinez, Elisabeth D.; Minna, John D.; Wright, Woodring E.; Shay, Jerry W. 分享 收藏
Identification of two small molecules with small cell lung cancer growth inhibition response profiles different from etoposide/topotecan Mootz, Allison A.; Peyton, Michael; Yenerall, Paul; Avila, Kimberley; Huffman, Kenneth; Haruki, Tomohiro; Papari-Zareei, Mahboubeh; Stastny, Victor; Girard, Luc; McMillan, Elizabeth; Roth, Michael; MacMillan, John; Posner, Bruce; White, Michael; Adi, Gazdar; Minna, John 分享 收藏
TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer Gong, Ke; Guo, Gao; Gerber, David E.; Gao, Boning; Peyton, Michael; Huang, Chun; Minna, John D.; Hatanpaa, Kimmo J.; Kernstine, Kemp; Cai, Ling; Xie, Yang; Zhu, Hong; Fattah, Farjana J.; Zhang, Shanrong; Takahashi, Masaya; Mukherjee, Bipasha; Burma, Sandeep; Dowell, Jonathan; Dao, Kathryn; Papadimitrakopoulou, Vassiliki A.; Olivas, Victor; Bivona, Trever G.; Zhao, Dawen; Habib, Amyn A. 分享 收藏
Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis Zhou, Xiaorong; Updegraff, Barrett L.; Guo, Yabin; Peyton, Michael; Girard, Luc; Larsen, Jill E.; Xie, Xian-Jin; Zhou, Yunyun; Hwang, Tae Hyun; Xie, Yang; Rodriguez-Canales, Jaime; Villalobos, Pamela; Behrens, Carmen; Ignacio, Wistuba I.; Minna, John D.; O'Donnell, Kathryn A. 分享 收藏
SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers Tagal, Vural; Wei, Shuguang; Zhang, Wei; Brekken, Rolf A.; Posner, Bruce A.; Peyton, Michael; Girard, Luc; Hwang, TaeHyun; Wheeler, David A.; Minna, John D.; White, Michael A.; Gazdar, Adi F.; Roth, Michael G. 分享 收藏
PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis Zhou, Xiaorong; Updegraff, Barrett L.; Guo, Yabin; Peyton, Michael; Girard, Luc; Larsen, Jill E.; Xie, Xian-Jin; Zhou, Yunyun; Hwang, Tae Hyun; Xie, Yang; Rodriguez-Canales, Jaime; Villalobos, Pamela; Behrens, Carmen; Wistuba, Ignacio I.; Minna, John D.; O'Donnell, Kathryn A. 分享 收藏
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Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities 共同发生的基因组改变定义了KRAS突变型肺腺癌的主要子集，具有不同的生物学，免疫谱和治疗脆弱性 Skoulidis, Ferdinandos; Byers, Lauren A.; Diao, Lixia; Papadimitrakopoulou, Vassiliki A.; Tong, Pan; Izzo, Julie; Behrens, Carmen; Kadara, Humam; Parra, Edwin R.; Canales, Jaime Rodriguez; Zhang, Jianjun; Giri, Uma; Gudikote, Jayanthi; Cortez, Maria A.; Yang, Chao; Fan, Youhong; Peyton, Michael; Girard, Luc; Coombes, Kevin R.; Toniatti, Carlo; Heffernan, Timothy P.; Choi, Murim; Frampton, Garrett M.; Miller, Vincent; Weinstein, John N.; Herbst, Roy S.; Wong, Kwok-Kin; Zhang, Jianhua; Sharma, Padmanee; Mills, Gordon B.; Hong, Waun K.; Minna, John D.; Allison, James P.; Futreal, Andrew; Wang, Jing; Wistuba, Ignacio I.; Heymach, John V. 分享 收藏
Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma (LUAC) with distinct biology and therapeutic vulnerabilities Skoulidis, Ferdinandos; Byers, Lauren; Diao, Lixia; Papadimitrakopoulou, Vassiliki; Tong, Pan; Izzo, Julie; Behrens, Carmen; Kadara, Humam; Parra, Edwin R.; Rodriguez-Canales, Jaime; Zhang, Jianjun; Giri, Uma; Gudikote, Jayanthi; Cortez, Maria Angelica; Yang, Chao; Fan, You Hong; Peyton, Michael; Girard, Luc; Coombes, Kevin R.; Toniatti, Carlo; Heffernan, Timothy P.; Choi, Murim; Frampton, Garrett M.; Miller, Vincent; Weinstein, John N.; Herbst, Roy S.; Wong, Kwok-Kin; Zhang, Jianhua; Sharma, Padmanee; Mills, Gordon M.; Hong, Waun Ki; Minna, John D.; Allison, James P.; Futreal, Andrew; Wang, Jing; Wistuba, Ignacio; Heymach, John V. 分享 收藏
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