David B. Ascher - Publications, H-index & Citations

David B. Ascher

university of queensland

61H指数

333论文数

2.0W被引数

收录论文 134

发表时间

Tracking breast cancer progression using Methylscape 利用Methylscape追踪乳腺癌进展

Science Advances

IF12.5

2026-08-28

OAAI

Zhen Zhang; Emtiaz Ahmed; Nicolas Constantin; Jennifer Lu; Stephanie Portelli; David B. Ascher; Darren Korbie; Alain Wuethrich; Abu Ali Ibn Sina; Matt Trau

Transformers as a substrate for structural biology Transformer作为结构生物学的基础

Current Opinion in Structural Biology

IF7

2026-02-06

PREAI

Ashar J. Malik; Stephanie Portelli; David B. Ascher

mCSM-metal: A Deep Learning Resource to Predict Effect of Mutations on Metal Ion Binding

Journal of Molecular Biology

IF4.5

2026-02-05

PREAI

Akshita Kumar; Ashar J. Malik; David B. Ascher

Systematic evaluation of computational tools to predict the effects of mutations on protein-ligand binding affinity in the absence of experimental structures 对缺乏实验结构条件下，用于预测突变对蛋白质-配体结合亲和力影响的计算工具的系统评价

Briefings in Bioinformatics

IF7.7

2026-02-05

OAAI

Qisheng Pan; Stephanie Portelli; Thanh Binh Nguyen; David B Ascher

Structome-AlignViewer: On Confidence Assessment in Structure-Aware Alignments 结构组-对齐查看器：结构感知对齐中的置信度评估

Genome Biology and Evolution

IF2.8

2026-01-01

PREAI

Malik, Ashar J.; Mao, Siying; Hugenholtz, Philip; Ascher, David B.

Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK biobank 探索ME/CFS中代谢扰动的遗传基础：使用UK biobank

iScience

IF4.1

2025-12-03

OAAI

Katherine Huang; Muhammad Muneeb; Natalie Thomas; Elena K. Schneider-Futschik; Paul R. Gooley; David B. Ascher; Christopher W. Armstrong

kinCSM-RTK: Machine Learning-Based Screening of Receptor Tyrosine Kinase Inhibitors in Drug Discovery

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2025-12-01

PREAI

Serghini, Adam; Zhou, Yunzhuo; Myung, Yoochan; de Sa, Alex G. C.; Portelli, Stephanie; Ascher, David B.

Combinatorial Discovery of RAFT Cationic Polymers for mRNA Delivery: Structure–Function Insights from High-Throughput Screening and Machine Learning 组合发现用于mRNA递送的RAFT阳离子聚合物：高通量筛选和机器学习得到的结构-功能见解

Biomacromolecules

IF5.4

2025-10-07

PREAI

Wenting Yang; Shangqian Li; Siqi Yu; Alex G. C. de Sá; Tanmayee Sai Sivani Ita; Tian Liang; Helen Forgham; Ruirui Qiao; Jiulong Li; Patrick S. Stayton; David B. Ascher; Huan Meng; Andrew K. Whittaker; Changkui Fu

Haploinsufficient variants in SMAD5 are associated with isolated congenital heart disease SMAD5基因中的剂量敏感性不足变异与孤立性先天性心脏病相关

Human Genetics and Genomics Advances

IF3.6

2025-07-05

OAAI

Dimuthu Alankarage; Iryna Leshchynska; Stephanie Portelli; Alena Sipka; Gillian M. Blue; Victoria O’Reilly; Debjani Das; Emma M. Rath; Annabelle Enriquez; Michael Troup; Miriam Fine; Nicola Poplawski; Maxim Verlee; David T. Humphreys; Richard P. Harvey; Gavin Chapman; Edwin P. Kirk; David S. Winlaw; Bert Callewaert; Wendy K. Chung; David Ascher; Eleni Giannoulatou; Sally L. Dunwoodie

Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites 邻近蛋白质组学揭示了脂质滴-线粒体-内质网接触位点上的脂肪酸转移机制

NATURE COMMUNICATIONS

IF15.7

2025-03-03

OAAI

Bezawork-Geleta, Ayenachew; Devereux, Camille J.; Keenan, Stacey N.; Lou, Jieqiong; Cho, Ellie; Nie, Shuai; De Souza, David P.; Narayana, Vinod K.; Siddall, Nicole A.; Rodrigues, Carlos H. M.; Portelli, Stephanie; Zheng, Tenghao; Nim, Hieu T.; Ramialison, Mirana; Hime, Gary R.; Dodd, Garron T.; Hinde, Elizabeth; Ascher, David B.; Stroud, David A.

Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges

HUMAN GENETICS

IF3.6

2025-02-20

PREAI

Turina, Paola; Petrosino, Maria; Enriquez Sandoval, Carlos A.; Novak, Leonore; Pasquo, Alessandra; Alexov, Emil; Alladin, Muttaqi Ahmad; Ascher, David B.; Babbi, Giulia; Bakolitsa, Constantina; Casadio, Rita; Cheng, Jianlin; Fariselli, Piero; Folkman, Lukas; Kamandula, Akash; Katsonis, Panagiotis; Li, Minghui; Li, Dong; Lichtarge, Olivier; Mahmud, Sajid; Martelli, Pier Luigi; Pal, Debnath; Panday, Shailesh Kumar; Pires, Douglas E. V.; Portelli, Stephanie; Pucci, Fabrizio; Rodrigues, Carlos H. M.; Rooman, Marianne; Savojardo, Castrense; Schwersensky, Martin; Shen, Yang; Strokach, Alexey V.; Sun, Yuanfei; Woo, Junwoo; Radivojac, Predrag; Brenner, Steven E.; Chiaraluce, Roberta; Consalvi, Valerio; Capriotti, Emidio

Drug resistance-associated mutations in Plasmodium UBP-1 disrupt its essential deubiquitinating activity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-02-01

OAAI

Smith, Cameron J.; Eavis, Heledd; Briggs, Carla; Henrici, Ryan; Karpiyevich, Maryia; Ansbro, Megan R.; Hoshizaki, Johanna; van Noort, Gerbrand J. van der Heden; Ascher, David B.; Sutherland, Colin J.; Lee, Marcus C. S.; Artavanis-Tsakonas, Katerina

Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges

HUMAN GENETICS

IF3.6

2024-12-23

PREAI

Turina, Paola; Dal Cortivo, Giuditta; Sandoval, Carlos A. Enriquez; Alexov, Emil; Ascher, David B.; Babbi, Giulia; Bakolitsa, Constantina; Casadio, Rita; Fariselli, Piero; Folkman, Lukas; Kamandula, Akash; Katsonis, Panagiotis; Li, Dong; Lichtarge, Olivier; Martelli, Pier Luigi; Panday, Shailesh Kumar; Pires, Douglas E. V.; Portelli, Stephanie; Pucci, Fabrizio; Rodrigues, Carlos H. M.; Rooman, Marianne; Savojardo, Castrense; Schwersensky, Martin; Shen, Yang; Strokach, Alexey V.; Sun, Yuanfei; Woo, Junwoo; Radivojac, Predrag; Brenner, Steven E.; Dell'Orco, Daniele; Capriotti, Emidio

Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank

COMMUNICATIONS MEDICINE

IF6.3

2024-11-26

OAAI

Huang, Katherine; de Sa, Alex G. C.; Thomas, Natalie; Phair, Robert D.; Gooley, Paul R.; Ascher, David B.; Armstrong, Christopher W.

A new method for network bioinformatics identifies novel drug targets for mucinous ovarian carcinoma

genomics proteomics bioinformatics

IF2.8

2024-08-24

OAAI

Craig, Olivia; Lee, Samuel; Pilcher, Courtney; Saoud, Rita; Abdirahman, Suad; Salazar, Carolina; Williams, Nathan; Ascher, David B.; Vary, Robert; Luu, Jennii; Cowley, Karla J.; Ramm, Susanne; Li, Mark Xiang; Thio, Niko; Li, Jason; Semple, Tim; Simpson, Kaylene J.; Gorringe, Kylie L.; Holien, Jessica K.

piscesCSM: prediction of anticancer synergistic drug combinations piscesCSM: 抗癌协同药物组合的预测

JOURNAL OF CHEMINFORMATICS

IF5.7

2024-07-19

OAAI

AlJarf, Raghad; Rodrigues, Carlos H. M.; Myung, Yoochan; Pires, Douglas E. V.; Ascher, David B.

DDMut-PPI: predicting effects of mutations on protein-protein interactions using graph-based deep learning

NUCLEIC ACIDS RESEARCH

IF13.1

2024-05-23

OAAI

Zhou, Yunzhuo; Myung, Yoochan; Rodrigues, Carlos H. M.; Ascher, David B.

Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-05-13

OAAI

King, Harry R.; Bycroft, Mark; Nguyen, Thanh-Binh; Kelly, Geoff; Vinogradov, Alexander A.; Rowling, Pamela J. E.; Stott, Katherine; Ascher, David B.; Suga, Hiroaki; Itzhaki, Laura S.; Artavanis -Tsakonas, Katerina

Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification

NATURE GENETICS

IF31.8

2024-04-24

PREAI

Ryu, Jayoung; Barkal, Sam; Yu, Tian; Jankowiak, Martin; Zhou, Yunzhuo; Francoeur, Matthew; Phan, Quang Vinh; Li, Zhijian; Tognon, Manuel; Brown, Lara; Love, Michael I.; Bhat, Vineel; Lettre, Guillaume; Ascher, David B.; Cassa, Christopher A.; Sherwood, Richard I.; Pinello, Luca

Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction

NUCLEIC ACIDS RESEARCH

IF13.1

2024-04-18

OAAI

Myung, Yoochan; de Sa, Alex G. C.; Ascher, David B.

研究方向