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G

Gennaro Napolitano

telethon institute of genetics and medicine
H指数:28
被引数:1.2万

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A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation

TBK1/ULK1信号轴将溶酶体应激与TFEB激活相偶联

Nature
IF48.5
2026-09-300
PRE
Alessandra Esposito; Ibrahim Bayramoglu; Chiara Varriale; Maria Pia Cavaliere; Maria Elsa Brunetti; Rossella Agostinis; Rachel M. Jansen; Dan A. Tudorica; Yongjia Duan; Martina Spacci; Alessia Calcagnì; Carolin D. Strobl; Verena Passerini; Fabrizio Andreone; Jlenia Monfregola; Julia Richter; Francesca Sacco; Wolfram Klapper; Oliver Weigert; Andrea Ballabio; Roberto Zoncu; James H. Hurley; Joern Dengjel; Gennaro Napolitano
A network-based approach to overcome BCR::ABL1-independent resistance in chronic myeloid leukemia (vol 23, 179, 2025)

基于网络的策略以克服慢性髓性白血病中BCR::ABL1非依赖性耐药（vol 23, 179, 2025）

CELL COMMUNICATION AND SIGNALING
IF8.9
2025-04-280
OA
Bica, Valeria; Venafra, Veronica; Massacci, Giorgia; Graziosi, Simone; Gualdi, Sara; Minnella, Gessica; Sora, Federica; Chiusolo, Patrizia; Brunetti, Maria Elsa; Napolitano, Gennaro; Breccia, Massimo; Mougiakakos, Dimitrios; Boettcher, Martin; Fischer, Thomas; Perfetto, Livia; Sacco, Francesca
A network-based approach to overcome BCR::ABL1-independent resistance in chronic myeloid leukemia

一种基于网络的方法来克服BCR:: 慢性粒细胞白血病的ABL1-independent耐药性

CELL COMMUNICATION AND SIGNALING
IF8.9
2025-04-100
OAAI
Bica, Valeria; Venafra, Veronica; Massacci, Giorgia; Graziosi, Simone; Gualdi, Sara; Minnella, Gessica; Sora, Federica; Chiusolo, Patrizia; Brunetti, Maria Elsa; Napolitano, Gennaro; Breccia, Massimo; Mougiakakos, Dimitrios; Boettcher, Martin; Fischer, Thomas; Perfetto, Livia; Sacco, Francesca
TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex
NATURE COMMUNICATIONS
IF15.7
2024-01-0910
OAAI
Alesi, Nicola; Khabibullin, Damir; Rosenthal, Dean M.; Akl, Elie W.; Cory, Pieter M.; Alchoueiry, Michel; Salem, Samer; Daou, Melissa; Gibbons, William F.; Chen, Jennifer A.; Zhang, Long; Filippakis, Harilaos; Graciotti, Laura; Miceli, Caterina; Monfregola, Jlenia; Vilardo, Claudia; Morroni, Manrico; Di Malta, Chiara; Napolitano, Gennaro; Ballabio, Andrea; Henske, Elizabeth P.
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury (vol 22, pg 1252, 2020)
NATURE CELL BIOLOGY
IF19.1
2022-10-040
OA
Nakamura, Shuhei; Shigeyama, Saki; Minami, Satoshi; Shima, Takayuki; Akayama, Shiori; Matsuda, Tomoki; Esposito, Alessandra; Napolitano, Gennaro; Kuma, Akiko; Namba-Hamano, Tomoko; Nakamura, Jun; Yamamoto, Kenichi; Sasai, Miwa; Tokumura, Ayaka; Miyamoto, Mika; Oe, Yukako; Fujita, Toshiharu; Terawaki, Seigo; Takahashi, Atsushi; Hamasaki, Maho; Yamamoto, Masahiro; Okada, Yukinori; Komatsu, Masaaki; Nagai, Takeharu; Takabatake, Yoshitsugu; Xu, Haoxing; Isaka, Yoshitaka; Ballabio, Andrea; Yoshimori, Tamotsu
Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy
SCIENCE ADVANCES
IF12.5
2022-09-0218
OAAI
Di Lorenzo, Giorgia; Iavarone, Francescopaolo; Maddaluno, Marianna; Belen Plata-Gomez, Ana; Aureli, Simone; Meza, Camila Paz Quezada; Cinque, Laura; Palma, Alessandro; Reggio, Alessio; Cirillo, Carmine; Sacco, Francesca; Stolz, Alexandra; Napolitano, Gennaro; Marin, Oriano; Pinna, Lorenzo A.; Ruzzene, Maria; Limongelli, Vittorio; Efeyan, Alejo; Grumati, Paolo; Settembre, Carmine
Current methods to analyze lysosome morphology, positioning, motility and function
TRAFFIC
IF2.5
2022-04-2464
OAAI
Barral, Duarte C.; Staiano, Leopoldo; Guimas Almeida, Claudia; Cutler, Dan F.; Eden, Emily R.; Futter, Clare E.; Galione, Antony; Marques, Andre R. A.; Medina, Diego Luis; Napolitano, Gennaro; Settembre, Carmine; Vieira, Otilia V.; Aerts, Johannes M. F. G.; Atakpa-Adaji, Peace; Bruno, Gemma; Capuozzo, Antonella; De Leonibus, Elvira; Di Malta, Chiara; Escrevente, Cristina; Esposito, Alessandra; Grumati, Paolo; Hall, Michael J.; Teodoro, Rita O.; Lopes, Susana S.; Luzio, J. Paul; Monfregola, Jlenia; Montefusco, Sandro; Platt, Frances M.; Polishchuck, Roman; De Risi, Maria; Sambri, Irene; Soldati, Chiara; Seabra, Miguel C.
Fluoxetine ameliorates mucopolysaccharidosis type IIIA
MOLECULAR THERAPY
IF12
2022-04-0113
OAAI
Capuozzo, Antonella; Montefusco, Sandro; Cacace, Vincenzo; Sofia, Martina; Esposito, Alessandra; Napolitano, Gennaro; Nusco, Eduardo; Polishchuk, Elena; Pizzo, Maria Teresa; De Risi, Maria; De Leonibus, Elvira; Sorrentino, Nicolina Cristina; Medina, Diego Luis
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype

他莫昔芬的再利用改善了CLN3和CLN7疾病表型

EMBO MOLECULAR MEDICINE
IF8.3
2021-08-1932
OAAI
Soldati, Chiara; Lopez-Fabuel, Irene; Wanderlingh, Luca G.; Garcia-Macia, Marina; Monfregola, Jlenia; Esposito, Alessandra; Napolitano, Gennaro; Guevara-Ferrer, Marta; Scotto Rosato, Anna; Krogsaeter, Einar K.; Paquet, Dominik; Grimm, Christian M.; Montefusco, Sandro; Braulke, Thomas; Storch, Stephan; Mole, Sara E.; De Matteis, Maria A.; Ballabio, Andrea; Sampaio, Julio L.; McKay, Tristan; Johannes, Ludger; Bolanos, Juan P.; Medina, Diego L.
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury

在对肾损伤的溶酶体损伤反应期间，LC3脂质化对于TFEB活化至关重要

NATURE CELL BIOLOGY
IF19.1
2020-09-28135
PREAI
Nakamura, Shuhei; Shigeyama, Saki; Minami, Satoshi; Shima, Takayuki; Akayama, Shiori; Matsuda, Tomoki; Esposito, Alessandra; Napolitano, Gennaro; Kuma, Akiko; Namba-Hamano, Tomoko; Nakamura, Jun; Yamamoto, Kenichi; Sasai, Miwa; Tokumura, Ayaka; Miyamoto, Mika; Oe, Yukako; Fujita, Toshiharu; Terawaki, Seigo; Takahashi, Atsushi; Hamasaki, Maho; Yamamoto, Masahiro; Okada, Yukinori; Komatsu, Masaaki; Nagai, Takeharu; Takabatake, Yoshitsugu; Xu, Haoxing; Isaka, Yoshitaka; Ballabio, Andrea; Yoshimori, Tamotsu

研究方向

暂未获取到该数据
A
Andrea Ballabio
H 指数:120论文数:595被引数:7.5万
J
Jlenia Monfregola
H 指数:23论文数:52被引数:2,431
A
Alessandra Esposito
H 指数:11论文数:19被引数:1,445
S
Sergio Catz
H 指数:35论文数:103被引数:7,005
J
Jennifer L. Johnson
H 指数:31论文数:114被引数:3,268
D
Diego L. Medina
H 指数:41论文数:121被引数:2.3万
F
Francesca Sacco
H 指数:20论文数:91被引数:3,211
C
Chiara Di Malta
H 指数:21论文数:35被引数:1.0万
J
Jing He
H 指数:21论文数:70被引数:1,916
S
Sandro Montefusco
H 指数:18论文数:71被引数:2,734