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A

Arne van Hoeck

University Medical Center Utrecht
H指数:29
被引数:8,689

个人简介

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教育背景

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工作经历

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荣誉奖项

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Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers

在早期结直肠癌中，肿瘤胚胎可塑性普遍存在

Nature
IF48.5
2026-04-150
OA
Julian R. Buissant des Amorie; Joris H. Hageman; Sascha R. Brunner; Suzanne E. M. van der Horst; Maria C. Puschhof; Arne van Hoeck; Inge van Lierop; Sjors Middelkamp; Lisa van der Schee; Sven van Kempen; Folkert Morsink; Robin Geene; Sander Mertens; David S. Cavigelli; Ingrid Verlaan-Klink; Lianne J. Kraaier; Jorieke Salij; Renate Bezemer; Onno Kranenburg; Miangela M. Laclé; Leon M. G. Moons; Hugo J. G. Snippert
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer

均聚物开关介导错配修复缺陷型结直肠癌的适应性可变性

NATURE GENETICS
IF31.8
2024-07-031
OAAI
Kayhanian, Hamzeh; Cross, William; van der Horst, Suzanne E. M.; Barmpoutis, Panagiotis; Lakatos, Eszter; Caravagna, Giulio; Zapata, Luis; Van Hoeck, Arne; Middelkamp, Sjors; Litchfield, Kevin; Steele, Christopher; Waddingham, William; Patel, Dominic; Milite, Salvatore; Jin, Chen; Baker, Ann-Marie; Alexander, Daniel C.; Khan, Khurum; Hochhauser, Daniel; Novelli, Marco; Werner, Benjamin; van Boxtel, Ruben; Hageman, Joris H.; Buissant des Amorie, Julian R.; Linares, Josep; Ligtenberg, Marjolijn J. L.; Nagtegaal, Iris D.; Lacle, Miangela M.; Moons, Leon M. G.; Brosens, Lodewijk A. A.; Pillay, Nischalan; Sottoriva, Andrea; Graham, Trevor A.; Rodriguez-Justo, Manuel; Shiu, Kai-Keen; Snippert, Hugo J. G.; Jansen, Marnix
EXO1 protects BRCA1-deficient cells against toxic DNA lesions
MOLECULAR CELL
IF16.6
2024-02-0110
OAAI
van de Kooij, Bert; Schreuder, Anne; Pavani, Raphael; Garzero, Veronica; Uruci, Sidrit; Wendel, Tiemen J.; Hoeck, Arne van; Alonso, Marta San Martin; Everts, Marieke; Koerse, Dana; Callen, Elsa; Boom, Jasper; Mei, Hailiang; Cuppen, Edwin; Luijsterburg, Martijn S.; van Vugt, Marcel A. T. M.; Nussenzweig, Andre; van Attikum, Haico; Noordermeer, Sylvie M.
Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests
ONCOGENE
IF7.3
2022-06-0310
OAAI
Meijer, Titia G.; Nguyen, Luan; Van Hoeck, Arne; Sieuwerts, Anieta M.; Verkaik, Nicole S.; Ladan, Marjolijn M.; Ruigrok-Ritstier, Kirsten; van Deurzen, Carolien H. M.; van de Werken, Harmen J. G.; Lips, Esther H.; Linn, Sabine C.; Memari, Yasin; Davies, Helen; Nik-Zainal, Serena; Kanaar, Roland; Martens, John W. M.; Cuppen, Edwin; Jager, Agnes; van Gent, Dik C.
Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

基因毒性pks大肠杆菌引起的结直肠癌的突变特征

Nature
IF48.5
2020-02-270
PREAI
Cayetano Pleguezuelos-Manzano; Jens Puschhof; Axel Rosendahl Huber; Arne van Hoeck; Henry M. Wood; Jason Nomburg; Carino Gurjao; Freek Manders; Guillaume Dalmasso; Paul B. Stege; Fernanda L. Paganelli; Maarten H. Geurts; Joep Beumer; Tomohiro Mizutani; Yi Miao; Reinier van der Linden; Stefan van der Elst; K. Christopher Garcia; Janetta Top; Rob J. L. Willems; Marios Giannakis; Richard Bonnet; Phil Quirke; Matthew Meyerson; Edwin Cuppen; Ruben van Boxtel; Hans Clevers
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening

胰腺癌类器官重述疾病并允许个性化药物筛选

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-12-09297
OAAI
Driehuis, Else; van Hoeck, Arne; Moore, Kat; Kolders, Sigrid; Francies, Hayley E.; Gulersonmez, M. Can; Stigter, Edwin C. A.; Burgering, Boudewijn; Geurts, Veerle; Gracanin, Ana; Bounova, Gergana; Morsink, Folkert H.; Vries, Robert; Boj, Sylvia; van Es, Johan; Offerhaus, G. Johan A.; Kranenburg, Onno; Garnett, Mathew J.; Wessels, Lodewyk; Cuppen, Edwin; Brosens, Lodewijk A. A.; Clevers, Hans
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies
NATURE GENETICS
IF31.8
2019-09-30226
OAAI
Angus, Lindsay; Smid, Marcel; Wilting, Saskia M.; van Riet, Job; Van Hoeck, Arne; Luan Nguyen; Nik-Zainal, Serena; Steenbruggen, Tessa G.; Tjan-Heijnen, Vivianne C. G.; Labots, Mariette; van Riel, Johanna M. G. H.; Bloemendal, Haiko J.; Steeghs, Neeltje; Lolkema, Martijn P.; Voest, Emile E.; van de Werken, Harmen J. G.; Jager, Agnes; Cuppen, Edwin; Sleijfer, Stefan; Martens, John W. M.

研究方向

暂未获取到该数据
E
Edwin Cuppen
H 指数:102论文数:534被引数:4.9万
R
Ruben van Boxtel
H 指数:46论文数:211被引数:1.8万
L
Luan Nguyen
H 指数:14论文数:39被引数:1,748
N
Nicolle Besselink
H 指数:21论文数:72被引数:2,086
E
Ewart Kuijk
H 指数:27论文数:61被引数:5,087
J
John W.M. Martens
H 指数:100论文数:913被引数:4.9万
H
Hans Clevers
H 指数:236论文数:1,340被引数:24.9万
O
Onno Kranenburg
H 指数:60论文数:359被引数:1.3万
R
Roel Janssen
H 指数:17论文数:57被引数:1,883
B
Bastiaan van der Roest
H 指数:8论文数:22被引数:686