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Somatic copy number variant load in neurons of healthy controls and Alzheimer's disease patients Turan, Zeliha Gozde; Richter, Vincent; Bochmann, Jana; Parvizi, Poorya; Yapar, Etka; Isildak, Ulas; Waterholter, Sarah-Kristin; Leclere-Turbant, Sabrina; Son, Cagdas Devrim; Duyckaerts, Charles; Yet, Idil; Arendt, Thomas; Somel, Mehmet; Ueberham, Uwe 分享 收藏
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation 来自DNA甲基化遗传效应图谱的基因组和表型见解 Min, Josine L.; Hemani, Gibran; Hannon, Eilis; Dekkers, Koen F.; Castillo-Fernandez, Juan; Luijk, Rene; Carnero-Montoro, Elena; Lawson, Daniel J.; Burrows, Kimberley; Suderman, Matthew; Bretherick, Andrew D.; Richardson, Tom G.; Klughammer, Johanna; Iotchkova, Valentina; Sharp, Gemma; Al Khleifat, Ahmad; Shatunov, Aleksey; Iacoangeli, Alfredo; McArdle, Wendy L.; Ho, Karen M.; Kumar, Ashish; Soderhall, Cilia; Soriano-Tarraga, Carolina; Giralt-Steinhauer, Eva; Kazmi, Nabila; Mason, Dan; McRae, Allan F.; Corcoran, David L.; Sugden, Karen; Kasela, Silva; Cardona, Alexia; Day, Felix R.; Cugliari, Giovanni; Viberti, Clara; Guarrera, Simonetta; Lerro, Michael; Gupta, Richa; Bollepalli, Sailalitha; Mandaviya, Pooja; Zeng, Yanni; Clarke, Toni-Kim; Walker, Rosie M.; Schmoll, Vanessa; Czamara, Darina; Ruiz-Arenas, Carlos; Rezwan, Faisal, I; Marioni, Riccardo E.; Lin, Tian; Awaloff, Yvonne; Germain, Marine; Aissi, Dylan; Zwamborn, Ramona; van Eijk, Kristel; Dekker, Annelot; van Dongen, Jenny; Hottenga, Jouke-Jan; Willemsen, Gonneke; Xu, Cheng-Jian; Barturen, Guillermo; Catala-Moll, Francesc; Kerick, Martin; Wang, Carol; Melton, Phillip; Elliott, Hannah R.; Shin, Jean; Bernard, Manon; Yet, Idil; Smarts, Melissa; Gorrie-Stone, Tyler; Shaw, Chris; Al Chalabi, Ammar; Ring, Susan M.; Pershagen, Goran; Melen, Erik; Jimenez-Conde, Jordi; Roquer, Jaume; Lawlor, Deborah A.; Wright, John; Martin, Nicholas G.; Montgomery, Grant W.; Moffitt, Terrie E.; Poulton, Richie; Esko, Tonu; Milani, Lili; Metspalu, Andres; Perry, John R. B.; Ong, Ken K.; Wareham, Nicholas J.; Matullo, Giuseppe; Sacerdote, Carlotta; Panico, Salvatore; Caspi, Avshalom; Arseneault, Louise; Gagnon, France; Ollikainen, Miina; Kaprio, Jaakko; Felix, Janine F.; Rivadeneira, Fernando; Tiemeier, Henning; van IJzendoorn, Marinus H.; Uitterlinden, Andre G.; Jaddoe, Vincent W. V.; Hale, Chris; McIntosh, Andrew M.; Evans, Kathryn L.; Murray, Alison; Raikkonen, Katri; Lahti, Jari; Nohr, Ellen A.; Sorensen, Thorkild I. A.; Hansen, Torben; Morgen, Camilla S.; Binder, Elisabeth B.; Lucae, Susanne; Gonzalez, Juan Ramon; Bustamante, Mariona; Sunyer, Jordi; Holloway, John W.; Karmaus, Wilfried; Zhang, Hongmei; Deary, Ian J.; Wray, Naomi R.; Starr, John M.; Beekman, Marian; VanHeemst, Diana; Slagboom, P. Eline; Morange, Pierre-Emmanuel; Tregouet, David-Alexandre; Veldink, Jan H.; Davies, Gareth E.; de Geus, Eco J. C.; Boomsma, Dorret, I; Vonk, Judith M.; Brunekreef, Bert; Koppelman, Gerard H.; Alarcon-Riquelme, Marta E.; Huang, Rae-Chi; Pennell, Craig E.; van Meurs, Joyce; Ikram, M. Arfan; Hughes, Alun D.; Tillin, Therese; Chaturvedi, Nish; Pausova, Zdenka; Paus, Tomas; Spector, Timothy D.; Kumari, Meena; Schalkwyk, Leonard C.; Visscher, Peter M.; Smith, George Davey; Bock, Christoph; Gaunt, Tom R.; Bell, Jordana T.; Heijmans, Bastiaan T.; Mill, Jonathan; Relton, Caroline L. 分享 收藏
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging 全基因组关联研究确定衰老的DNA甲基化生物标志物的137遗传位点 McCartney, Daniel L.; Min, Josine L.; Richmond, Rebecca C.; Lu, Ake T.; Sobczyk, Maria K.; Davies, Gail; Broer, Linda; Guo, Xiuqing; Jeong, Ayoung; Jung, Jeesun; Kasela, Silva; Katrinli, Seyma; Kuo, Pei-Lun; Matias-Garcia, Pamela R.; Mishra, Pashupati P.; Nygaard, Marianne; Palviainen, Teemu; Patki, Amit; Raffield, Laura M.; Ratliff, Scott M.; Richardson, Tom G.; Robinson, Oliver; Soerensen, Mette; Sun, Dianjianyi; Tsai, Pei-Chien; van der Zee, Matthijs D.; Walker, Rosie M.; Wang, Xiaochuan; Wang, Yunzhang; Xia, Rui; Xu, Zongli; Yao, Jie; Zhao, Wei; Correa, Adolfo; Boerwinkle, Eric; Dugue, Pierre-Antoine; Durda, Peter; Elliott, Hannah R.; Gieger, Christian; de Geus, Eco J. C.; Harris, Sarah E.; Hemani, Gibran; Imboden, Medea; Kahonen, Mika; Kardia, Sharon L. R.; Kresovich, Jacob K.; Li, Shengxu; Lunetta, Kathryn L.; Mangino, Massimo; Mason, Dan; McIntosh, Andrew M.; Mengel-From, Jonas; Moore, Ann Zenobia; Murabito, Joanne M.; Ollikainen, Miina; Pankow, James S.; Pedersen, Nancy L.; Peters, Annette; Polidoro, Silvia; Porteous, David J.; Raitakari, Olli; Rich, Stephen S.; Sandler, Dale P.; Sillanpaa, Elina; Smith, Alicia K.; Southey, Melissa C.; Strauch, Konstantin; Tiwari, Hemant; Tanaka, Toshiko; Tillin, Therese; Uitterlinden, Andre G.; van den Berg, David J.; van Dongen, Jenny; Wilson, James G.; Wright, John; Yet, Idil; Arnett, Donna; Bandinelli, Stefania; Bell, Jordana T.; Binder, Alexandra M.; Boomsma, Dorret I.; Chen, Wei; Christensen, Kaare; Conneely, Karen N.; Elliott, Paul; Ferrucci, Luigi; Fornage, Myriam; Hagg, Sara; Hayward, Caroline; Irvin, Marguerite; Kaprio, Jaakko; Lawlor, Deborah A.; Lehtimaki, Terho; Lohoff, Falk W.; Milani, Lili; Milne, Roger L.; Probst-Hensch, Nicole; Reiner, Alex P.; Ritz, Beate; Rotter, Jerome; Smith, Jennifer A.; Taylor, Jack A.; van Meurs, Joyce B. J.; Vineis, Paolo; Waldenberger, Melanie; Deary, Ian J.; Relton, Caroline L.; Horvath, Steve; Marioni, Riccardo E. 分享 收藏
Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium van der Spek, Ashley; Broer, Linda; Draisma, Harmen H. M.; Pool, Rene; Albrecht, Eva; Beekman, Marian; Mangino, Massimo; Raag, Mait; Nyholt, Dale R.; Dharuri, Harish K.; Codd, Veryan; Amin, Najaf; de Geus, Eco J. C.; Deelen, Joris; Demirkan, Ayse; Yet, Idil; Fischer, Krista; Haller, Toomas; Henders, Anjali K.; Isaacs, Aaron; Medland, Sarah E.; Montgomery, Grant W.; Mooijaart, Simon P.; Strauch, Konstantin; Suchiman, H. Eka D.; Vaarhorst, Anika A. M.; van Heemst, Diana; Wang-Sattler, Rui; Whitfield, John B.; Willemsen, Gonneke; Wright, Margaret J.; Martin, Nicholas G.; Samani, Nilesh J.; Metspalu, Andres; Slagboom, P. Eline; Spector, Tim D.; Boomsma, Dorret, I; van Duijn, Cornelia M.; Gieger, Christian 分享 收藏
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health Tsai, Pei-Chien; Glastonbury, Craig A.; Eliot, Melissa N.; Bollepalli, Sailalitha; Yet, Idil; Castillo-Fernandez, Juan E.; Carnero-Montoro, Elena; Hardiman, Thomas; Martin, Tiphaine C.; Vickers, Alice; Mangino, Massimo; Ward, Kirsten; Pietilaeinen, Kirsi H.; Deloukas, Panos; Spector, Tim D.; Vinuela, Ana; Loucks, Eric B.; Ollikainen, Miina; Kelsey, Karl T.; Small, Kerrin S.; Bell, Jordana T. 分享 收藏
GWAS of epigenetic aging rates in blood reveals a critical role for TERT Lu, Ake T.; Xue, Luting; Salfati, Elias L.; Chen, Brian H.; Ferrucci, Luigi; Levy, Daniel; Joehanes, Roby; Murabito, Joanne M.; Kiel, Douglas P.; Tsai, Pei-Chien; Yet, Idil; Bell, Jordana T.; Mangino, Massimo; Tanaka, Toshiko; McRae, Allan F.; Marioni, Riccardo E.; Visscher, Peter M.; Wray, Naomi R.; Deary, Ian J.; Levine, Morgan E.; Quach, Austin; Assimes, Themistocles; Tsao, Philip S.; Absher, Devin; Stewart, James D.; Li, Yun; Reiner, Alex P.; Hou, Lifang; Baccarelli, Andrea A.; Whitsel, Eric A.; Aviv, Abraham; Cardona, Alexia; Day, Felix R.; Wareham, Nicholas J.; Perry, John R. B.; Ong, Ken K.; Raj, Kenneth; Lunetta, Kathryn L.; Horvath, Steve 分享 收藏
Genetic Variation at 16q24.2 Is Associated With Small Vessel Stroke Traylor, Matthew; Malik, Rainer; Nalls, Mike A.; Cotlarciuc, Ioana; Radmanesh, Farid; Thorleifsson, Gudmar; Hanscombe, Ken B.; Langefeld, Carl; Saleheen, Danish; Rost, Natalia S.; Yet, Idil; Spector, Tim D.; Bell, Jordana T.; Hannon, Eilis; Mill, Jonathan; Chauhan, Ganesh; Debette, Stephanie; Bis, Joshua C.; Longstreth, W. T., Jr.; Ikram, M. Arfan; Launer, Lenore J.; Seshadri, Sudha; Hamilton-Bruce, Monica Anne; Jimenez-Conde, Jordi; Cole, John W.; Schmidt, Reinhold; Slowik, Agnieszka; Lemmens, Robin; Lindgren, Arne; Melander, Olle; Grewal, Raji P.; Sacco, Ralph L.; Rundek, Tatjana; Rexrode, Kathryn; Arnett, Donna K.; Johnson, Julie A.; Benavente, Oscar R.; Wasssertheil-Smoller, Sylvia; Lee, Jin-Moo; Pulit, Sara L.; Wong, Quenna; Rich, Stephen S.; de Bakker, Paul I. W.; McArdle, Patrick F.; Woo, Daniel; Anderson, Christopher D.; Xu, Huichun; Heitsch, Laura; Fornage, Myriam; Jern, Christina; Stefansson, Kari; Thorsteinsdottir, Unnur; Gretarsdottir, Solveig; Lewis, Cathryn M.; Sharma, Pankaj; Sudlow, Cathie L. M.; Rothwell, Peter M.; Boncoraglio, Giorgio B.; Thijs, Vincent; Levi, Chris; Meschia, James F.; Rosand, Jonathan; Kittner, Steven J.; Mitchell, Braxton D.; Dichgans, Martin; Worrall, Bradford B.; Markus, Hugh S. 分享 收藏
A DNA methylation biomarker of alcohol consumption Liu, C.; Marioni, R. E.; Hedman, A. K.; Pfeiffer, L.; Tsai, P-C; Reynolds, L. M.; Just, A. C.; Duan, Q.; Boer, C. G.; Tanaka, T.; Elks, C. E.; Aslibekyan, S.; Brody, J. A.; Kuehnel, B.; Herder, C.; Almli, L. M.; Zhi, D.; Wang, Y.; Huan, T.; Yao, C.; Mendelson, M. M.; Joehanes, R.; Liang, L.; Love, S-A; Guan, W.; Shah, S.; Mcrae, A. F.; Kretschmer, A.; Prokisch, H.; Strauch, K.; Peters, A.; Visscher, P. M.; Wray, N. R.; Guo, X.; Wiggins, K. L.; Smith, A. K.; Binder, E. B.; Ressler, K. J.; Irvin, M. R.; Absher, D. M.; Hernandez, D.; Ferrucci, L.; Bandinelli, S.; Lohman, K.; Ding, J.; Trevisi, L.; Gustafsson, S.; Sandling, J. H.; Stolk, L.; Uitterlinden, A. G.; Yet, I.; Castillo-Fernandez, J. E.; Spector, T. D.; Schwartz, J. D.; Vokonas, P.; Lind, L.; Li, Y.; Fornage, M.; Arnett, D. K.; Wareham, N. J.; Sotoodehnia, N.; Ong, K. K.; van Meurs, J. B. J.; Conneely, K. N.; Baccarelli, A. A.; Deary, I. J.; Bell, J. T.; North, K. E.; Liu, Y.; Waldenberger, M.; London, S. J.; Ingelsson, E.; Levy, D. 分享 收藏
Heritable components of the human fecal microbiome are associated with visceral fat 人类粪便微生物组的可遗传成分与内脏脂肪有关 Beaumont, Michelle; Goodrich, Julia K.; Jackson, Matthew A.; Yet, Idil; Davenport, Emily R.; Vieira-Silva, Sara; Debelius, Justine; Pallister, Tess; Mangino, Massimo; Raes, Jeroen; Knight, Rob; Clark, Andrew G.; Ley, Ruth E.; Spector, Tim D.; Bell, Jordana T. 分享 收藏
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Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels Draisma, Harmen H. M.; Pool, Rene; Kobl, Michael; Jansen, Rick; Petersen, Ann-Kristin; Vaarhorst, Anika A. M.; Yet, Idil; Haller, Toomas; Demirkan, Ayse; Esko, Tonu; Zhu, Gu; Boehringer, Stefan; Beekman, Marian; van Klinken, Jan Bert; Roemisch-Margl, Werner; Prehn, Cornelia; Adamski, Jerzy; de Craen, Anton J. M.; van Leeuwen, Elisabeth M.; Amin, Najaf; Dharuri, Harish; Westra, Harm-Jan; Franke, Lude; de Geus, Eco J. C.; Hottenga, Jouke Jan; Willemsen, Gonneke; Henders, Anjali K.; Montgomery, Grant W.; Nyholt, Dale R.; Whitfield, John B.; Penninx, Brenda W.; Spector, Tim D.; Metspalu, Andres; Slagboom, P. Eline; van Dijk, Ko Willems; 't Hoen, Peter A. C.; Strauch, Konstantin; Martin, Nicholas G.; van Ommen, Gert-Jan B.; Illig, Thomas; Bell, Jordana T.; Mangino, Massimo; Suhre, Karsten; McCarthy, Mark I.; Gieger, Christian; Isaacs, Aaron; van Duijn, Cornelia M.; Boomsma, Dorret I. 分享 收藏
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins Yuan, Wei; Xia, Yudong; Bell, Christopher G.; Yet, Idil; Ferreira, Teresa; Ward, Kirsten J.; Gao, Fei; Loomis, A. Katrina; Hyde, Craig L.; Wu, Honglong; Lu, Hanlin; Liu, Yuan; Small, Kerrin S.; Vinuela, Ana; Morris, Andrew P.; Berdasco, Maria; Esteller, Manel; Brosnan, M. Julia; Deloukas, Panos; McCarthy, Mark I.; John, Sally L.; Bell, Jordana T.; Wang, Jun; Spector, Tim D. 分享 收藏
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