未登录 First-in-child phase I trial of p-STAT3 inhibitor WP1066 in pediatric brain tumor patients Castellino, Robert C.; Mumme, Hope; Franson, Andrea; Yu, Bing; Robinson, Hope; Dhodapkar, Kavita; Aguilera, Dolly; Schniederjan, Matthew; Keesari, Rohali; He, Zhulin; Bhasin, Manoj; Priebe, Waldemar; Heimberger, Amy B.; Macdonald, Tobey J. 分享 收藏
Robust activation and clonal expansion of early, non-exhausted, stem-like endogenous T cells induced by chemo-immunotherapy treatment in patients with pediatric brain tumors is predictive of clinical outcome 在儿科脑肿瘤患者中，由化疗免疫疗法治疗诱导的早期、非耗竭、干细胞样内源T细胞的稳健激活和克隆扩增，可预测临床结局。 Johnson, Theodore S.; Pacholczyk, Rafal; Satpathy, Sarthak; Berrong, Zuzana; Chien, Franklin; Huang, Chenbin; Thomas, Beena E.; Chi, Susan N.; Baird, Lissa; Sadek, Ramses F.; Friedman, Gregory; Hummel, Trent R.; Yeo, Kee Kiat; Macdonald, Tobey J.; Bhasin, Manoj K.; Munn, David H. 分享 收藏
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CIRCULATING TUMOR CELLS IN MEDULLOBLASTOMA: A NOVEL PERIPHERAL BIOMARKER FOR CNS DISEASE Ozkaya, Tevhide; Chien, Franklin; Boya, Mert; Gray, Rachel; Arthur, Robert; Claussen, Henry; Vega, Jose Velazquez-Vega Velazquez; Schneiderjan, Matthew; Bhasin, Manoj; Sarioglu, Fatih; Macdonald, Tobey 分享 收藏
A phase 1 study of abemaciclib, a CDK 4/6 inhibitor, with radiation in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG) Cash, Thomas; Aguilera, Dolly; He, Zhulin; Schink, Melissa; Sykes, Amanda; Pitou, Celine; Connelly, Erin; Eaton, Bree; Esiashvili, Natia; Mangum, Ross; Macy, Margaret E.; Castellino, Robert C.; Fangusaro, Jason; MacDonald, Tobey J.; Wetmore, Cynthia; Hoffman, Lindsey 分享 收藏
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ANAPLASTIC TRANSFORMATION OF DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMORS: TWO PEDIATRIC CASES Aguilera, Dolly; Janss, Anna; Schniederjan, Matthew; Goldman-Yassen, Adam; Velazquez, Jose; Mazewski, Claire; Gray, Rachel; Macdonald, Tobey; Fangusaro, Jason; Castellino, Robert Craig 分享 收藏
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PHASE 1 STUDY OF THE CD40 AGONISTIC MONOCLONAL ANTIBODY APX005M (SOTIGALIMAB) IN PEDIATRIC, ADOLESCENT, AND YOUNG ADULT PATIENTS WITH RECURRENT OR PROGRESSIVE CNS TUMORS AND NEWLY DIAGNOSED BRAIN STEM GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM STUDY (PBTC-051; NCT03389802) Lindsay, Holly B.; Billups, Catherine; Baxter, Patricia; Hwang, Eugene; Lenzen, Alicia; MacDonald, Tobey; Pollack, Ian F.; Robison, Nathan; Vinitsky, Anna; Poussaint, Tina Young; Onar-Thomas, Arzu; Fangusaro, Jason; Dunkel, Ira J. 分享 收藏
PHASE 2 TRIAL USING INDOXIMOD-BASED CHEMO-IMMUNOTHERAPY FOR PATIENTS WITH CHILDHOOD BRAIN CANCER: INTERIM ANALYSIS OF THE GCC1949 STUDY (NCT04049669) Johnson, Theodore S.; Pacholczyk, Rafal; Ring, Eric K.; Aguilera, Dolly; Castellino, Robert C.; Fangusaro, Jason R.; Eaton, Bree R.; Chi, Susan; Yeo, Kee Kiat; Hummel, Trent R.; Berrong, Zuzana; Creager, Julianne; Ingerski, Lisa; Schniederjan, Matthew; Huang, Chenbin; Satpathy, Sarthak; Thomas, Beena E.; Sadek, Ramses F.; Kennedy, Eugene P.; Bhasin, Manoj K.; Macdonald, Tobey J.; Munn, David H. 分享 收藏
Safety and pharmacokinetics of ONC201 (dordaviprone) administered two consecutive days per week in pediatric patients with H3 K27M-mutant glioma Odia, Yazmin; Koschmann, Carl; Vitanza, Nicholas A.; de Blank, Peter; Aguilera, Dolly; Allen, Jeffrey; Daghistani, Doured; Hall, Matthew; Khatib, Ziad; Kline, Cassie; Macdonald, Tobey; Mueller, Sabine; Faison, Shamia L.; Allen, Joshua E.; Naderer, Odin J.; Ramage, Samuel C.; Tarapore, Rohinton S.; Mcgovern, Susan Lynne; Khatua, Soumen; Zaky, Wafik; Gardner, Sharon L. 分享 收藏
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Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial Johnson, Theodore S.; MacDonald, Tobey J.; Pacholczyk, Rafal; Aguilera, Dolly; Al-Basheer, Ahmad; Bajaj, Manish; Bandopadhayay, Pratiti; Berrong, Zuzana; Bouffet, Eric; Castellino, Robert C.; Dorris, Kathleen; Eaton, Bree R.; Esiashvili, Natia; Fangusaro, Jason R.; Foreman, Nicholas; Fridlyand, Diana; Giller, Cole; Heger, Ian M.; Huang, Chenbin; Kadom, Nadja; Kennedy, Eugene P.; Manoharan, Neevika; Martin, William; McDonough, Colleen; Parker, Rebecca S.; Ramaswamy, Vijay; Ring, Eric; Rojiani, Amyn; Sadek, Ramses F.; Satpathy, Sarthak; Schniederjan, Matthew; Smith, Amy; Smith, Christopher; Thomas, Beena E.; Vaizer, Rachel; Yeo, Kee Kiat; Bhasin, Manoj K.; Munn, David H. 分享 收藏
The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival Shahab, Shubin W.; Roggeveen, Christianna M.; Sun, Jiarong; Kunhiraman, Haritha; McSwain, Leon F.; Juraschka, Kyle; Kumar, Sachin A.; Saulnier, Olivier; Taylor, Michael D.; Schniederjan, Matthew; Schnepp, Robert W.; MacDonald, Tobey J.; Kenney, Anna Marie 分享 收藏
YB1 modulates the DNA damage response in medulloblastoma (vol 13, 8087, 2023) McSwain, Leon F. F.; Pillsbury, Claire E. E.; Haji-Seyed-Javadi, Ramona; Rath, Sandip Kumar; Chen, Victor; Huang, Tiffany; Shahab, Shubin W. W.; Kunhiraman, Haritha; Ross, James; Price, Gabrielle A. A.; Dey, Abhinav; Hambardzumyan, Dolores; MacDonald, Tobey; Yu, David S. S.; Porter, Christopher C. C.; Kenney, Anna M. M. 分享 收藏
INTERIM ANALYSIS OF THE GCC1949 PHASE 2 TRIAL USING INDOXIMOD-BASED CHEMO-IMMUNOTHERAPY FOR PATIENTS WITH PEDIATRIC BRAIN TUMORS Johnson, Theodore S.; Pacholczyk, Rafal; Aguilera, Dolly; Berrong, Zuzana; Castellino, Robert C.; Chi, Susan; Creager, Julianne; Eaton, Bree R.; Fangusaro, Jason R.; Huang, Chenbin; Hummel, Trent; Ingerski, Lisa; Kennedy, Eugene P.; Ring, Eric; Sadek, Ramses F.; Satpathy, Sarthak; Schniederjan, Matthew; Thomas, Beena E.; Yeo, Kee Kiat; Bhasin, Manoj; MacDonald, Tobey J.; Munn, David H. 分享 收藏
OUTCOMES UTILIZING BRAF INHIBITION MONOTHERAPY IN BRAFV600E MUTATED PEDIATRIC LOW GRADE GLIOMAS McThenia, Sheila; Reddy, Kartik; Goldman-Yassen, Adam E.; Gray, Rachel; Connelly, Erin; Patteson, Brooke; Aguilera, Dolly; Castellino, Robert Craig; Fangusaro, Jason Ronald; Janss, Anna; Mazewski, Claire; MacDonald, Tobey 分享 收藏
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