Shizhong Han - Publications, H-index & Citations

Shizhong Han

Lieber Institute for Brain Development

36H指数

139论文数

5.0K被引数

收录论文 45

发表时间

Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer’s vulnerability 人脑蓝斑中的分子程序将APOE和神经黑色素与阿尔茨海默病易感性联系起来

Acta Neuropathologica

IF9.3

2026-09-11

PREAI

Bernard Mulvey; Heena R. Divecha; Madhavi Tippani; Svitlana V. Bach; Rahul Bharadwaj; Ishbel Del Rosario; Sarah E. Maguire; Ryan A. Miller; Aaron J. Salisbury; Atharv Chandra; Beau A. Oster; Kelsey D. Montgomery; Sang Ho Kwon; Haya A. Algrain; Alexis R. Papariello; Louise A. Huuki-Myers; Joel E. Kleinman; Leonardo Collado-Torres; Thomas M. Hyde; Shizhong Han; Stephanie C. Hicks; Daniel R. Weinberger; Stephanie C. Page; Kristen R. Maynard; Keri Martinowich

SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia SETD1A调控涉及基因组稳定性和突触功能的精神病基因网络，在罕见和散发型精神分裂症中发挥作用。

Nature Communications

IF15.7

2025-12-20

OAAI

Tomoyo Sawada; Arthur S. Feltrin; Yanhong Wang; Bruno Araujo; Alejandra E. McCord; Hunter H. Giles; Shizhong Han; Eugenia Radulescu; Qiang Chen; Bareera Qamar; André R. Barbosa; Ricardo S. Jacomini; Alan P. R. Lorenzetti; Violeta Dimitrova; Radka Kaneva; Vladimir Vladimirov; Joel E. Kleinman; Thomas M. Hyde; Daniel R. Weinberger; Apuã C. M. Paquola; Jennifer A. Erwin

An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus 整合单核与空间转录组学图谱揭示了人类海马体的分子景观

Nature Neuroscience

IF20

2025-07-30

OAAI

Jacqueline R. Thompson; Erik D. Nelson; Madhavi Tippani; Anthony D. Ramnauth; Heena R. Divecha; Ryan A. Miller; Nicholas J. Eagles; Elizabeth A. Pattie; Sang Ho Kwon; Svitlana V. Bach; Uma M. Kaipa; Jianing Yao; Christine Hou; Joel E. Kleinman; Leonardo Collado-Torres; Shizhong Han; Kristen R. Maynard; Thomas M. Hyde; Keri Martinowich; Stephanie C. Page; Stephanie C. Hicks

Classification of schizophrenia, bipolar disorder and major depressive disorder with comorbid traits and deep learning algorithms

SCHIZOPHRENIA

IF4.1

2025-02-05

OAAI

Chen, Xiangning; Lu, Yimei; Cue, Joan Manuel; Han, Mira V.; Nimgaonkar, Vishwajit L.; Weinberger, Daniel R.; Han, Shizhong; Zhao, Zhongming; Chen, Jingchun

Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex

BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE

IF3.7

2024-11-01

OAAI

White, Julie D.; Minto, Melyssa S.; Willis, Caryn; Quach, Bryan C.; Han, Shizhong; Tao, Ran; Deep-Soboslay, Amy; Zillich, Lea; Witt, Stephanie H.; Spanagel, Rainer; Hansson, Anita C.; Clark, Shaunna L.; van den Oord, Edwin J. C. G.; Hyde, Thomas M.; Mayfield, R. Dayne; Webb, Bradley T.; Johnson, Eric O.; Kleinman, Joel E.; Bierut, Laura J.; Hancock, Dana B.

Gene expression differences associated with alcohol use disorder in human brain

MOLECULAR PSYCHIATRY

IF10.1

2024-10-12

OAAI

Willis, Caryn; White, Julie D.; Minto, Melyssa S.; Quach, Bryan C.; Han, Shizhong; Tao, Ran; Shin, Joo Heon; Deep-Soboslay, Amy; Hyde, Thomas M.; Mayfield, R. Dayne; Webb, Bradley T.; Johnson, Eric O.; Kleinman, Joel E.; Bierut, Laura J.; Hancock, Dana B.

Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci

NEUROPSYCHOPHARMACOLOGY

IF7.1

2024-06-04

OAAI

Carnes, Megan Ulmer; Quach, Bryan C.; Zhou, Linran; Han, Shizhong; Tao, Ran; Mandal, Meisha; Deep-Soboslay, Amy; Marks, Jesse A.; Page, Grier P.; Maher, Brion S.; Jaffe, Andrew E.; Won, Hyejung; Bierut, Laura J.; Hyde, Thomas M.; Kleinman, Joel E.; Johnson, Eric O.; Hancock, Dana B.

Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia

PLOS GENETICS

IF3.7

2023-10-13

OAAI

Radulescu, Eugenia; Chen, Qiang; Pergola, Giulio; Di Carlo, Pasquale; Han, Shizhong; Shin, Joo Heon; Hyde, Thomas M.; Kleinman, Joel E.; Weinberger, Daniel R.

DEEP LEARNING PREDICTS BRAIN CELL TYPE-SPECIFIC REGULATORY VARIANTS FOR DNA METHYLATION AND IMPROVES FINE MAPPING FOR PSYCHIATRIC DISORDERS

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2023-10-01

PREAI

Han, Shizhong; Weinberger, Daniel

Prioritization of potential causative genes for schizophrenia in placenta

NATURE COMMUNICATIONS

IF15.7

2023-05-15

OAAI

Ursini, Gianluca; Di Carlo, Pasquale; Mukherjee, Sreya; Chen, Qiang; Han, Shizhong; Kim, Jiyoung; Deyssenroth, Maya; Marsit, Carmen J.; Chen, Jia; Hao, Ke; Punzi, Giovanna; Weinberger, Daniel R.

A self-inspected adaptive SMOTE algorithm (SASMOTE) for highly imbalanced data classification in healthcare

BIODATA MINING

IF6.1

2023-04-25

OAAI

Kosolwattana, Tanapol; Liu, Chenang; Hu, Renjie; Han, Shizhong; Chen, Hua; Lin, Ying

Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-08-15

OAAI

Zhou, Jiyun; Chen, Qiang; Braun, Patricia R.; Mandell, Kira A. Perzel; Jaffe, Andrew E.; Tan, Hao Yang; Hyde, Thomas M.; Kleinman, Joel E.; Potash, James B.; Shinozaki, Gen; Weinberger, Daniel R.; Han, Shizhong

Molecular phenotypes associated with antipsychotic drugs in the human caudate nucleus

MOLECULAR PSYCHIATRY

IF10.1

2022-03-02

OAAI

Mandell, Kira A. Perzel; Eagles, Nicholas J.; Deep-Soboslay, Amy; Tao, Ran; Han, Shizhong; Wilton, Richard; Szalay, Alexander S.; Hyde, Thomas M.; Kleinman, Joel E.; Jaffe, Andrew E.; Weinberger, Daniel R.

Effect of selection bias on two sample summary data based Mendelian randomization

SCIENTIFIC REPORTS

IF3.9

2021-04-07

OAAI

Wang, Kai; Han, Shizhong

Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals

TRANSLATIONAL PSYCHIATRY

IF6.2

2019-01-31

285

OAAI

Braun, Patricia R.; Han, Shizhong; Hing, Benjamin; Nagahama, Yasunori; Gaul, Lindsey N.; Heinzman, Jonathan T.; Grossbach, Andrew J.; Close, Liesl; Dlouhy, Brian J.; Howardiii, Matthew A.; Kawasaki, Hiroto; Potash, James B.; Shinozaki, Gen

GENOME-WIDE ASSOCIATION STUDY OF COMORBID ALCOHOL DEPENDENCE AND MAJOR DEPRESSION

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2019-01-01

PREAI

Zhou, Hang; Polimanti, Renato; Yang, Bao-Zhu; Wang, Qian; Han, Shizhong; Sherva, Richard; Nunez, Yaira; Zhao, Hongyu; Farrer, Lindsay; Kranzler, Henry; Gelernter, Joel

IMAGE-CpG: DEVELOPMENT OF A WEB-BASED SEARCH TOOL FOR GENOME-WIDE DNA METHYLATION CORRELATION BETWEEN LIVE HUMAN BRAIN AND PERIPHERAL TISSUES WITHIN INDIVIDUALS

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2019-01-01

PREAI

Braun, Patricia; Han, Shizhong; Nagahama, Yasunori; Gaul, Lindsey; Heinzman, Jonathan; Hing, Benjamin; Grossbach, Andrew; Dlouhy, Brian; Howard, Matthew; Kawasaki, Hiroto; Potash, James; Shinozaki, Gen

GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort

JOURNAL OF AFFECTIVE DISORDERS

IF4.9

2019-01-01

OAAI

Heinzman, Jonathan T.; Hoth, Karin F.; Cho, Michael H.; Sakornsakolpat, Phuwanat; Regan, Elizabeth A.; Make, Barry J.; Kinney, Gregory L.; Wamboldt, Frederick S.; Holm, Kristen E.; Bormann, Nicholas; Robles, Julian; Kim, Victor; Iyer, Anand S.; Silverman, Edwin K.; Crapo, James D.; Han, Shizhong; Potash, James B.; Shinozaki, Gen

Genome-wide association study of seasonal affective disorder

TRANSLATIONAL PSYCHIATRY

IF6.2

2018-09-14

OAAI

Ho, Kwo Wei David; Han, Shizhong; Nielsen, Jakob V.; Jancic, Dubravka; Hing, Benjamin; Fiedorowicz, Jess; Weissman, Myrna M.; Levinson, Douglas F.; Potash, James B.

Identifying noncoding risk variants using disease-relevant gene regulatory networks

NATURE COMMUNICATIONS

IF15.7

2018-02-16

OAAI

Gao, Long; Uzun, Yasin; Gao, Peng; He, Bing; Ma, Xiaoke; Wang, Jiahui; Han, Shizhong; Tan, Kai

研究方向