Cahir J. O’Kane - Publications, H-index & Citations

Cahir J. O’Kane

University of Cambridge

54H指数

125论文数

1.7W被引数

收录论文 53

发表时间

How neurons maintain their axons long-term: an integrated view of axon biology and pathology

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-07-26

OAAI

Smith, Gaynor; Sweeney, Sean T.; O'Kane, Cahir J.; Prokop, Andreas

Mushroom body output neurons MBON-a1/a2 define an odor intensity channel that regulates behavioral odor discrimination learning in larval Drosophila

FRONTIERS IN PHYSIOLOGY

IF3.4

2023-05-15

OAAI

Mohamed, Abdulkadir; Malekou, Iro; Sim, Timothy; O'Kane, Cahir J.; Maait, Yousef; Scullion, Benjamin; Masuda-Nakagawa, Liria M.

Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics

JOURNAL OF CELL BIOLOGY

IF6.4

2023-03-23

OAAI

Jose Perez-Moreno, Juan; Smith, Rebecca C.; Oliva, Megan K.; Gallo, Filomena; Ojha, Shainy; Muller, Karin H.; O'Kane, Cahir J.

Virtual Fly Brain—An interactive atlas of the Drosophila nervous system

FRONTIERS IN PHYSIOLOGY

IF3.4

2023-01-26

OAAI

Court, Robert; Costa, Marta; Pilgrim, Clare; Millburn, Gillian; Holmes, Alex; McLachlan, Alex; Larkin, Aoife; Matentzoglu, Nicolas; Kir, Huseyin; Parkinson, Helen; Brown, Nicolas H.; O'Kane, Cahir J.; Armstrong, J. Douglas; Jefferis, Gregory S. X. E.; Osumi-Sutherland, David

Editorial: Hereditary Spastic Paraplegias: At the Crossroads of Molecular Pathways and Clinical Options

FRONTIERS IN NEUROSCIENCE

IF3.2

2021-06-22

OAAI

Martinuzzi, Andrea; Blackstone, Craig; O'Kane, Cahir J.; Stevanin, Giovanni

A multicomponent screen for feeding behaviour and nutritional status in Drosophila to interrogate mammalian appetite-related genes

MOLECULAR METABOLISM

IF6.6

2021-01-01

OAAI

Chalmers, J.; Tung, Y. C. L.; Liu, C. H.; O'Kane, C. J.; O'Rahilly, S.; Yeo, G. S. H.

Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics

FRONTIERS IN NEUROSCIENCE

IF3.2

2020-08-10

OAAI

Oliva, Megan K.; Perez-Moreno, Juan Jose; O'Shaughnessy, Jillian; Wardill, Trevor J.; O'Kane, Cahir J.

Axonal Endoplasmic Reticulum Dynamics and Its Roles in Neurodegeneration

FRONTIERS IN NEUROSCIENCE

IF3.2

2020-01-29

OAAI

Ozturk, Zeynep; O'Kane, Cahir J.; Perez-Moreno, Juan Jose

Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins

ELIFE

IF0

2017-07-25

OAAI

Yalcin, Belgin; Zhao, Lu; Stofanko, Martin; O'Sullivan, Niamh C.; Kang, Zi Han; Roost, Annika; Thomas, Matthew R.; Zaessinger, Sophie; Blard, Oliver; Patto, Alex L.; Sohail, Anood; Baena, Valentina; Terasaki, Mark; O'Kane, Cahir J.

CCT complex restricts neuropathogenic protein aggregation via autophagy

NATURE COMMUNICATIONS

IF15.7

2016-12-08

108

OAAI

Pavel, Mariana; Imarisio, Sara; Menzies, Fiona M.; Jimenez-Sanchez, Maria; Siddiqi, Farah H.; Wu, Xiaoting; Renna, Maurizio; O'Kane, Cahir J.; Crowther, Damian C.; Rubinsztein, David C.

siRNA screen identifies QPCT as a druggable target for Huntington's disease

NATURE CHEMICAL BIOLOGY

IF13.7

2015-04-06

OAAI

Jimenez-Sanchez, Maria; Lam, Wun; Hannus, Michael; Soennichsen, Birte; Imarisio, Sara; Fleming, Angeleen; Tarditi, Alessia; Menzies, Fiona; Dami, Teresa Ed; Xu, Catherine; Gonzalez-Couto, Eduardo; Lazzeroni, Giulia; Heitz, Freddy; Diamanti, Daniela; Massai, Luisa; Satagopam, Venkata P.; Marconi, Guido; Caramelli, Chiara; Nencini, Arianna; Andreini, Matteo; Sardone, Gian Luca; Caradonna, Nicola P.; Porcari, Valentina; Scali, Carla; Schneider, Reinhard; Pollio, Giuseppe; O'Kane, Cahir J.; Caricasole, Andrea; Rubinsztein, David C.

PICALM modulates autophagy activity and tau accumulation (vol 5, 4998, 2014)

NATURE COMMUNICATIONS

IF15.7

2015-01-28

OAAI

Moreau, Kevin; Fleming, Angeleen; Imarisio, Sara; Ramirez, Ana Lopez; Mercer, Jacob L.; Jimenez-Sanchez, Maria; Bento, Carla F.; Puri, Claudia; Zavodszky, Eszter; Siddiqi, Farah; Lavau, Catherine P.; Betton, Maureen; O'Kane, Cahir J.; Wechsler, Daniel S.; Rubinsztein, David C.

Dyneins, autophagy, aggregation and neurodegeneration

AUTOPHAGY

IF14.3

2014-10-27

OAAI

Rubinsztein, DC; Ravikumar, B; Acevedo-Arozena, A; Imarisio, S; O'Kane, CJ; Brown, SDM

Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity

CELL DEATH AND DIFFERENTIATION

IF15.4

2014-09-26

OAAI

Menzies, F. M.; Garcia-Arencibia, M.; Imarisio, S.; O'Sullivan, N. C.; Ricketts, T.; Kent, B. A.; Rao, M. V.; Lam, W.; Green-Thompson, Z. W.; Nixon, R. A.; Saksida, L. M.; Bussey, T. J.; O'Kane, C. J.; Rubinsztein, D. C.

PICALM modulates autophagy activity and tau accumulation

NATURE COMMUNICATIONS

IF15.7

2014-09-22

209

OAAI

A single GABAergic neuron mediates feedback of odor-evoked signals in the mushroom body of larval Drosophila

FRONTIERS IN NEURAL CIRCUITS

IF3

2014-04-09

OAAI

Masuda-Nakagawa, Liria M.; Ito, Kei; Awasaki, Takeshi; O'Kane, Cahir J.

Characterization of the Drosophila Atlastin Interactome Reveals VCP as a Functionally Related Interactor

JOURNAL OF GENETICS AND GENOMICS

IF7.1

2013-06-01

PREAI

O'Sullivan, Niamh C.; Draeger, Nina; O'Kane, Cahir J.

Reticulon-like-1, the Drosophila orthologue of the Hereditary Spastic Paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons

HUMAN MOLECULAR GENETICS

IF3.2

2012-04-27

OAAI

O'Sullivan, Niamh C.; Jahn, Thomas R.; Reid, Evan; O'Kane, Cahir J.

Complex Inhibitory Effects of Nitric Oxide on Autophagy

MOLECULAR CELL

IF16.6

2011-07-01

352

OAAI

Sarkar, Sovan; Korolchuk, Viktor I.; Renna, Maurizio; Imarisio, Sara; Fleming, Angeleen; Williams, Andrea; Garcia-Arencibia, Moises; Rose, Claudia; Luo, Shouqing; Underwood, Benjamin R.; Kroemer, Guido; O'Kane, Cahir J.; Rubinsztein, David C.

Lysosomal positioning coordinates cellular nutrient responses

NATURE CELL BIOLOGY

IF19.1

2011-03-13

741

OAAI

Korolchuk, Viktor I.; Saiki, Shinji; Lichtenberg, Maike; Siddiqi, Farah H.; Roberts, Esteban A.; Imarisio, Sara; Jahreiss, Luca; Sarkar, Sovan; Futter, Marie; Menzies, Fiona M.; O'Kane, Cahir J.; Deretic, Vojo; Rubinsztein, David C.

研究方向