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T

Timothy C. Burn

incyte research institute
H指数:51
被引数:1.2万

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荣誉奖项

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TYRA-300, an oral, FGFR3-selective inhibitor: Preliminary pharmacokinetic and pharmacodynamic analysis from SURF301, the multicenter open-label phase 1/2 study of TYRA-300 in advanced urothelial carcinoma and other solid tumors with activating FGFR3 alterations
EUROPEAN JOURNAL OF CANCER
IF7.1
2024-10-010
PRE
Loriot, Y.; Zhang, A.; Hansen, A.; Mantia, C.; Boni, V.; Weickhardt, A.; Yu, E. Y.; Robert, M.; Iyer, G.; Murtha, A.; Owens, S.; Suttle, B.; Vandekerkhove, G.; Wyatt, A.; Gammon, G.; Burn, T.; Tran, B.
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
Nature
IF48.5
2022-08-100
OAAI
Daniel Zingg; Jinhyuk Bhin; Julia Yemelyanenko; Sjors M. Kas; Frank Rolfs; Catrin Lutz; Jessica K. Lee; Sjoerd Klarenbeek; Ian M. Silverman; Stefano Annunziato; Chang S. Chan; Sander R. Piersma; Timo Eijkman; Madelon Badoux; Ewa Gogola; Bjørn Siteur; Justin Sprengers; Bim de Klein; Richard R. de Goeij-de Haas; Gregory M. Riedlinger; Hua Ke; Russell Madison; Anne Paulien Drenth; Eline van der Burg; Eva Schut; Linda Henneman; Martine H. van Miltenburg; Natalie Proost; Huiling Zhen; Ellen Wientjens; Roebi de Bruijn; Julian R. de Ruiter; Ute Boon; Renske de Korte-Grimmerink; Bastiaan van Gerwen; Luis Féliz; Ghassan K. Abou-Alfa; Jeffrey S. Ross; Marieke van de Ven; Sven Rottenberg; Edwin Cuppen; Anne Vaslin Chessex; Siraj M. Ali; Timothy C. Burn; Connie R. Jimenez; Shridar Ganesan; Lodewyk F. A. Wessels; Jos Jonkers
Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing
BRITISH JOURNAL OF CANCER
IF6.8
2022-07-2335
OA
Neumann, Olaf; Burn, Timothy C.; Allgaeuer, Michael; Ball, Markus; Kirchner, Martina; Albrecht, Thomas; Volckmar, Anna-Lena; Beck, Susanne; Endris, Volker; Goldschmid, Hannah; Lehmann, Ulrich; Seker-Cin, Huriye; Uhrig, Sebastian; Roessler, Stephanie; Budczies, Jan; Froehling, Stefan; Longerich, Thomas; Wagner, Alex H.; Vogel, Arndt; Schirmacher, Peter; Stenzinger, Albrecht; Kazdal, Daniel
Discovery of Pemigatinib: A Potent and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-07-1645
PREAI
Wu, Liangxing; Zhang, Colin; He, Chunhong; Qian, Dingquan; Lu, Liang; Sun, Yaping; Xu, Meizhong; Zhuo, Jincong; Liu, Phillip C. C.; Klabe, Ronald; Wynn, Richard; Covington, Maryanne; Gallagher, Karen; Leffet, Lynn; Bowman, Kevin; Diamond, Sharon; Koblish, Holly; Zhang, Yue; Soloviev, Maxim; Hollis, Gregory; Burn, Timothy C.; Scherle, Peggy; Yeleswaram, Swamy; Huber, Reid; Yao, Wenqing
Parsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell Malignancy
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
2020-07-0135
OAAI
Shin, Niu; Stubbs, Matthew; Koblish, Holly; Yue, Eddy W.; Soloviev, Maxim; Douty, Brent; Wang, Kathy He; Wang, Qian; Gao, Mingming; Feldman, Patricia; Yang, Gengjie; Hall, Leslie; Hansbury, Michael; O'Connor, Sybil; Leffet, Lynn; Collins, Robert; Katiyar, Kamna; He, Xin; Waeltz, Paul; Collier, Paul; Lu, Jin; Li, Yun-Long; Li, Yanlong; Liu, Phillip C. C.; Burn, Timothy; Covington, Maryanne; Diamond, Sharon; Shuey, Dana; Roberts, Alan; Yeleswaram, Swamy; Hollis, Greg; Metcalf, Brian; Yao, Wenqing; Huber, Reid; Combs, Andrew; Newton, Robert; Scherle, Peggy
The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies
CLINICAL CANCER RESEARCH
IF10.2
2019-01-0335
OAAI
Stubbs, Matthew C.; Burn, Timothy C.; Sparks, Richard; Maduskuie, Thomas; Diamond, Sharon; Rupar, Mark; Wen, Xiaoming; Volgina, Alla; Zolotarjova, Nina; Waeltz, Paul; Favata, Margaret; Jalluri, Ravi; Liu, Huiqing; Liu, Xuesong Mike; Li, Jun; Collins, Robert; Falahatpisheh, Nikoo; Polam, Padmaja; DiMatteo, Darlise; Feldman, Patricia; Dostalik, Valerie; Thekkat, Pramod; Gardiner, Christine; He, Xin; Li, Yanlong; Covington, Maryanne; Wynn, Richard; Ruggeri, Bruce; Yeleswaram, Swamy; Xue, Chu-Biao; Yao, Wenqing; Combs, Andrew P.; Huber, Reid; Hollis, Gregory; Scherle, Peggy; Liu, Phillip C. C.
The LSD1 specific inhibitor INCB059872 enhances the activity of mechanistically distinct immunotherapeutic agents in the syngeneic 4T1 mouse mammary tumor model
MOLECULAR CANCER THERAPEUTICS
IF5.5
2018-01-010
PRE
Lee, Sang Hyun; Diamond, Melody; Chadderton, Antony; Condamine, Thomas; Liu, Huiqing; Roman, Valerie; Lu, Jin; Zhang, Yan; Soloviev, Maxim; He, Chunhong; Wu, Liangxing; Koblish, Holly; Burn, Timothy; Combs, Andrew; Yeleswaram, Swamy; Roberts, Alan; Yao, Wenqing; Hollis, Gregory; Huber, Reid; Scherle, Peggy; Ruggeri, Bruce
INCB040093 Is a Novel PI3Kδ Inhibitor for the Treatment of B Cell Lymphoid Malignancies
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
2018-01-0121
OAAI
Shin, Niu; Li, Yun-Long; Mei, Song; Wang, Kathy He; Hall, Leslie; Katiyar, Kamna; Wang, Qian; Yang, Gengjie; Rumberger, Beth; Leffet, Lynn; He, Xin; Rupar, Mark; Bowman, Kevin; Favata, Margaret; Li, Jun; Liu, Mike; Li, Yanlong; Covington, Maryanne; Koblish, Holly; Soloviev, Maxim; Shuey, Dana; Burn, Timothy; Diamond, Sharon; Fridman, Jordan; Combs, Andrew; Yao, Wenqing; Yeleswaram, Swamy; Hollis, Gregory; Vaddi, Kris; Huber, Reid; Newton, Robert; Scherle, Peggy
Preclinical characterization of the potent and selective BET inhibitor INCB057643 in models of hematologic malignancies
CANCER RESEARCH
IF16.6
2017-07-0110
PRE
Stubbs, Matthew C.; Maduskuie, Thomas; Burn, Timothy; Diamond-Fosbenner, Sharon; Falahatpisheh, Nikoo; Volgina, Alla; Zolotarjova, Nina; Wen, Xiaoming; Feldman, Patricia; Rupar, Mark; Collins, Robert; Marando, Cindy; Ruggeri, Bruce; Covington, Maryanne; Liu, Xuesong Mike; Wynn, Richard; Yeleswaram, Swamy; Yao, Wenqing; Huber, Reid; Hollis, Gregory; Scherle, Peggy; Combs, Andrew P.; Liu, Phillip C.
Selective inhibition of FGFR4 by INCB062079 is efficacious in models of FGF19-and FGFR4-dependent cancers
CANCER RESEARCH
IF16.6
2017-07-013
PRE
Liu, Phillip C. C.; Lu, Liang; Bowman, Kevin; Stubbs, Matthew C.; Wu, Liangxing; DiMatteo, Darlise; Condon, Sindy; Klabe, Ronald; Qian, Ding-Quan; Wen, Xiaoming; Collier, Paul; Gallagher, Karen; Hansbury, Michael; He, Xin; Ruggeri, Bruce; Yang, Yan-ou; Covington, Maryanne; Burn, Timothy C.; Diamond-Fosbenner, Sharon; Wynn, Richard; Huber, Reid; Yao, Wenqing; Yeleswaram, Swamy; Scherle, Peggy; Hollis, Gregory

研究方向

暂未获取到该数据
P
Peggy Scherle
H 指数:56论文数:386被引数:1.6万
G
Gregory Hollis
H 指数:44论文数:218被引数:8,337
R
Reid Huber
H 指数:28论文数:184被引数:5,399
A
Andrew P. Combs
H 指数:34论文数:166被引数:6,444
R
Richard Wynn
H 指数:54论文数:239被引数:1.0万
S
Swamy Yeleswaram
H 指数:34论文数:189被引数:4,107
W
Wenqing Yao
H 指数:31论文数:138被引数:3,589
M
Maryanne Covington
H 指数:39论文数:199被引数:6,178
K
Kris Vaddi
H 指数:39论文数:196被引数:9,977
H
Holly K. Koblish
H 指数:26论文数:115被引数:4,107