Brian Ciruna - Publications, H-index & Citations

Brian Ciruna

The Hospital for Sick Children

29H指数

68论文数

6.0K被引数

收录论文 32

发表时间

tRNA-overlapping long non-coding RNA loci repress codon-biased genes tRNA重叠的长链非编码RNA位点抑制密码子偏好性基因

Cell Reports

IF6.9

2025-10-09

OAAI

Sameen Ahmed; Jacob L. Fine; Jordan J. Chalmers; Katerina Kiriakopulos; Lindsay A. Clarke; Carla Casanova Suárez; Katty Soleimanpour; Winona Oliveros; Kate Delfosse; Milad Mokhtaridoost; Cassandra J. Wong; Anne-Claude Gingras; Brian Ciruna; Marc R. Fabian; Benjamin J. Blencowe; Philipp G. Maass

Oxidative stress-induced intervertebral disc remodelling and elevated stiffness drive idiopathic scoliosis in preclinical models 氧化应激诱导的椎间盘重塑和高刚度驱动预临床模型中的特发性脊柱侧凸

Nature Communications

IF15.7

2025-09-30

OAAI

Patrick G. Pumputis; Ran Xu; Josh Gopaul; Arash Panahifar; Vida Erfani; Jenica L. M. Van Gennip; B. Frank Eames; Nikan Fakhari; Jerome Baranger; David E. Lebel; Olivier Villemain; Brian Ciruna

Fluid shear stress activates a targetable mechano-metastatic cascade to promote medulloblastoma metastasis 流体剪切应力激活了一个可靶向的机械性转移级联，以促进髓母细胞瘤转移。

Nature Biomedical Engineering

IF26.6

2025-09-02

PREAI

Hyun-Kee Min; Hongyu Zhao; Alexander Bahcheli; Peng Pan; Jade Chan; Junsheng Chen; Esther Low; Yuxiao Zhou; Xian Wang; Savo Bajic; Ran Peng; Siyi Wanggou; Qi Yang; Robert Du Yang Zhang; Leiming Wang; Xiufang Ren; Haoyue Qi; Yu Shi; Madeline N. Hayes; Brian Ciruna; Jüri Reimand; Xinyu Liu; Xi Huang

Tissue stiffness mapping by light sheet elastography 光片弹性成像技术进行组织刚度成像

SCIENCE ADVANCES

IF12.5

2025-03-14

OAAI

Zhu, Min; Zhang, Kaiwen; Thomas, Evan C.; Xu, Ran; Ciruna, Brian

Two zebrafish cacna1s loss-of-function variants provide models of mild and severe CACNA1S-related myopathy

HUMAN MOLECULAR GENETICS

IF3.2

2023-10-31

OAAI

Endo, Yukari; Groom, Linda; Wang, Sabrina M.; Pannia, Emanuela; Griffiths, Nigel W.; Van Gennip, Jenica L. M.; Ciruna, Brian; Laporte, Jocelyn; Dirksen, Robert T.; Dowling, James J.

Loss of zebrafish pkd1l1 causes biliary defects that have implications for biliary atresia splenic malformation

DISEASE MODELS & MECHANISMS

IF3.3

2023-10-11

OAAI

Ali, Rouknuddin Q.; Meyer-Miner, Anne; David-Rachel, Marie; Lee, Fiona J. H.; Wilkins, Benjamin J.; Karpen, Saul J.; Ciruna, Brian; Ghanekar, Anand; Kamath, Binita M.

Apollo-NADP+ reveals in vivo adaptation of NADPH/NADP+ metabolism in electrically activated pancreatic β cells

SCIENCE ADVANCES

IF12.5

2023-10-06

OAAI

Bui, Cindy V.; Boswell, Curtis W.; Ciruna, Brian; Rocheleau, Jonathan V.

COL11A2 as a candidate gene for vertebral malformations and congenital scoliosis

HUMAN MOLECULAR GENETICS

IF3.2

2023-07-18

PREAI

Rebello, Denise; Wohler, Elizabeth; Erfani, Vida; Li, Guozhuang; Aguilera, Alexya N.; Santiago-Cornier, Alberto; Zhao, Sen; Hwang, Steven W.; Steiner, Robert D.; Zhang, Terry Jianguo; Gurnett, Christina A.; Raggio, Cathleen; Wu, Nan; Sobreira, Nara; Giampietro, Philip F.; Ciruna, Brian

Live imaging and conditional disruption of native PCP activity using endogenously tagged zebrafish sfGFP-Vangl2

NATURE COMMUNICATIONS

IF15.7

2022-09-23

OAAI

Jussila, Maria; Boswell, Curtis W.; Griffiths, Nigel W.; Pumputis, Patrick G.; Ciruna, Brian

The NEMP family supports metazoan fertility and nuclear envelope stiffness NEMP家族支持后生动物的生育能力和核膜硬度

SCIENCE ADVANCES

IF12.5

2020-08-28

OAAI

Tsatskis, Yonit; Rosenfeld, Robyn; Pearson, Joel D.; Boswell, Curtis; Qu, Yi; Kim, Kyunga; Fabian, Lacramioara; Mohammad, Ariz; Wang, Xian; Robson, Michael, I; Krchma, Karen; Wu, Jun; Goncalves, Joao; Hodzic, Didier; Wu, Shu; Potter, Daniel; Pelletier, Laurence; Dunham, Wade H.; Gingras, Anne-Claude; Sun, Yu; Meng, Jin; Godt, Dorothea; Schedl, Tim; Ciruna, Brian; Choi, Kyunghee; Perry, John R. B.; Bremner, Rod; Schirmer, Eric C.; Brill, Julie A.; Jurisicova, Andrea; McNeill, Helen

SCO-Spondin Defects and Neuroinflammation Are Conserved Mechanisms Driving Spinal Deformity across Genetic Models of Idiopathic Scoliosis

CURRENT BIOLOGY

IF7.5

2020-06-01

OAAI

Rose, Chloe D.; Pompili, David; Henke, Katrin; Van Gennip, Jenica L. M.; Meyer-Miner, Anne; Rana, Rahul; Gobron, Stephane; Harris, Matthew P.; Nitz, Mark; Ciruna, Brian

Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy

NATURE COMMUNICATIONS

IF15.7

2020-01-30

OAAI

Hengel, Holger; Bosso-Lefevre, Celia; Grady, George; Szenker-Ravi, Emmanuelle; Li, Hankun; Pierce, Sarah; Lebigot, Elise; Tan, Thong-Teck; Eio, Michelle Y.; Narayanan, Gunaseelan; Utami, Kagistia Hana; Yau, Monica; Handal, Nader; Deigendesch, Werner; Keimer, Reinhard; Marzouqa, Hiyam M.; Gunay-Aygun, Meral; Muriello, Michael J.; Verhelst, Helene; Weckhuysen, Sarah; Mahida, Sonal; Naidu, Sakkubai; Thomas, Terrence G.; Lim, Jiin Ying; Tan, Ee Shien; Haye, Damien; Willemsen, Michel A. A. P.; Oegema, Renske; Mitchell, Wendy G.; Pierson, Tyler Mark; Andrews, Marisa V.; Willing, Marcia C.; Rodan, Lance H.; Barakat, Tahsin Stefan; van Slegtenhorst, Marjon; Gavrilova, Ralitza H.; Martinelli, Diego; Gilboa, Tal; Tamim, Abdullah M.; Hashem, Mais O.; AlSayed, Moeenaldeen D.; Abdulrahim, Maha M.; Al-Owain, Mohammed; Awaji, Ali; Mahmoud, Adel A. H.; Faqeih, Eissa A.; Al Asmari, Ali; Algain, Sulwan M.; Jad, Lamyaa A.; Aldhalaan, Hesham M.; Helbig, Ingo; Koolen, David A.; Riess, Angelika; Kraegeloh-Mann, Ingeborg; Bauer, Peter; Gulsuner, Suleyman; Stamberger, Hannah; Ng, Alvin Yu Jin; Tang, Sha; Tohari, Sumanty; Keren, Boris; Schultz-Rogers, Laura E.; Klee, Eric W.; Barresi, Sabina; Tartaglia, Marco; Mor-Shaked, Hagar; Maddirevula, Sateesh; Begtrup, Amber; Telegrafi, Aida; Pfundt, Rolph; Schuele, Rebecca; Ciruna, Brian; Bonnard, Carine; Pouladi, Mahmoud A.; Stewart, James C.; Claridge-Chang, Adam; Lefeber, Dirk J.; Alkuraya, Fowzan S.; Mathuru, Ajay S.; Venkatesh, Byrappa; Barycki, Joseph J.; Simpson, Melanie A.; Jamuar, Saumya S.; Schoels, Ludger; Reversade, Bruno

Neuroinflammatory signals drive spinal curve formation in zebrafish models of idiopathic scoliosis

SCIENCE ADVANCES

IF12.5

2018-12-07

OAAI

Van Gennip, J. L. M.; Boswell, C. W.; Ciruna, B.

Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development

PLOS GENETICS

IF3.7

2018-11-26

OAAI

Konjikusic, Mia J.; Yeetong, Patra; Boswell, Curtis W.; Lee, Chanjae; Roberson, Elle C.; Ittiwut, Rungnapa; Suphapeetiporn, Kanya; Ciruna, Brian; Gurnett, Christina A.; Wallingford, John B.; Shotelersuk, Vorasuk; Gray, Ryan S.

Understanding Idiopathic Scoliosis: A New Zebrafish School of Thought

TRENDS IN GENETICS

IF16.3

2017-03-01

PREAI

Boswell, Curtis W.; Ciruna, Brian

Anisotropy Imaging of Apollo-NADP+ In Vivo to Track NADPH Dynamics in the Pancreatic Beta Cells of Living Zebrafish

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

Bui, Cindy V.; Boswell, Curtis W.; McFaul, Christopher M.; Yip, Christopher M.; Ciruna, Brian; Rocheleau, Jonathan V.

Anisotropic stress orients remodelling of mammalian limb bud ectoderm

NATURE CELL BIOLOGY

IF19.1

2015-04-20

102

OAAI

Lau, Kimberly; Tao, Hirotaka; Liu, Haijiao; Wen, Jun; Sturgeon, Kendra; Sorfazlian, Natalie; Lazic, Savo; Burrows, Jeffrey T. A.; Wong, Michael D.; Li, Danyi; Deimling, Steven; Ciruna, Brian; Scott, Ian; Simmons, Craig; Henkelman, R. Mark; Williams, Trevor; Hadjantonakis, Anna-Katerina; Fernandez-Gonzalez, Rodrigo; Sun, Yu; Hopyan, Sevan

The clathrin adaptor AP-1 complex and Arf1 regulate planar cell polarity in vivo

NATURE COMMUNICATIONS

IF15.7

2015-04-07

OAAI

Carvajal-Gonzalez, Jose Maria; Balmer, Sophie; Mendoza, Meg; Dussert, Aurore; Collu, Giovanna; Roman, Angel-Carlos; Weber, Ursula; Ciruna, Brian; Mlodzik, Marek

ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease

NATURE COMMUNICATIONS

IF15.7

2014-09-03

134

OAAI

Hayes, Madeline; Gao, Xiaochong; Yu, Lisa X.; Paria, Nandina; Henkelman, R. Mark; Wise, Carol A.; Ciruna, Brian

IFT88 Plays a Cilia- and PCP-Independent Role in Controlling Oriented Cell Divisions during Vertebrate Embryonic Development

CELL REPORTS

IF6.9

2013-10-01

OAAI

Borovina, Antonia; Ciruna, Brian

研究方向