Mikako Shirouzu - Publications, H-index & Citations

Mikako Shirouzu

riken

75H指数

795论文数

2.1W被引数

收录论文 197

发表时间

Structural basis for auto-inhibition of the Rac1/Cdc42 guanine nucleotide exchange factor DOCK6 by oligomer formation DOCK6寡聚体形成对Rac1/Cdc42鸟嘌呤核苷酸交换因子的自抑制的结构基础

Communications Biology

IF5.1

2026-05-29

OAAI

Mutsuko Kukimoto-Niino; Kazushige Katsura; Kota Yoshimura; Yoshiko Ishizuka-Katsura; Yuki Miyamoto; Mayumi Yonemochi; Kazuharu Hanada; Junji Yamauchi; Richard W. Wong; Mikako Shirouzu

Downregulation of claudin-2 expression and chemoresistance by saquinavir in human lung adenocarcinoma cells 沙奎那韦下调人肺腺癌细胞中Claudin-2表达和化疗耐药性

European Journal of Pharmacology

IF4.7

2026-05-02

PREAI

Sayaka Komoto; Riho Kimura; Yuta Yoshino; Kazushi Morimoto; Takehiro Shinoda; Mikako Shirouzu; Yoshinobu Ishikawa; Toshiyuki Matsunaga; Satoshi Endo; Akira Ikari

CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting CXCR4诱导car-t细胞耗竭后的记忆形成以实现持久的白血病靶向

Nature Communications

IF15.7

2026-01-26

OAAI

Ari Itoh-Nakadai; Minggao Liang; Michiho Shindo; Chen Bibi; Mariko Tomizawa-Murasawa; Saera Fujiki; Akiko Kaneko; Emi Kanamaru; Mari Hashimoto; Hiroshi Kajita; Yoshinari Ando; Miki Kojima; Jonathan Moody; Makoto Iwasaki; Shinsuke Takagi; Ryo Nakagawa; Saumya Agrawal; Hanae Amitani-Iijima; Kaori Sato; Yuriko Sorimachi; Nahoko Suzuki; Takehiro Fukami; Kazuharu Hanada; Satoshi Morita; Kazushige Katsura; Takehisa Matsumoto; Maiko Kobayashi; Masahiko Kato; Yasuyuki Negishi; Mikako Shirouzu; Yuho Najima; Keiyo Takubo; Chung Chau Hon; Naoyuki Uchida; Shuichi Taniguchi; Yukihide Momozawa; Piero Carninci; Leonard D. Shultz; Yoriko Saito; Michiel de Hoon; Jay W. Shin; Fumihiko Ishikawa

Hypoxia-induced ribosomal RNA modifications in the peptidyl-transferase center contribute to anaerobic growth of bacteria 缺氧诱导的核糖体RNA修饰在肽基转移酶中心，有助于细菌的厌氧生长。

Molecular Cell

IF16.6

2025-12-10

OAAI

Kensuke Ishiguro; Karin Midorikawa; Naoki Shigi; Satoshi Kimura; Aivar Liiv; Takeshi Yokoyama; Takuhiro Ito; Mikako Shirouzu; Jaanus Remme; Kenjyo Miyauchi; Tsutomu Suzuki

1H, 13C, and 15N resonance assignments and solution structure of the CID domain of SR-related- and CTD-associated factor 8 (SCAF8)1H、13C和15N共振信号分配以及SR相关-CTD相关因子8（SCAF8）的CID结构域的溶液结构

BIOMOLECULAR NMR ASSIGNMENTS

IF0.6

2025-12-09

PREAI

Dang, Weirong; Muto, Yutaka; He, Fahu; Takahashi, Mari; Tsuda, Kengo; Nagata, Takashi; Tanaka, Akiko; Kobayashi, Naohiro; Kigawa, Takanori; Guentert, Peter; Shirouzu, Mikako; Yokoyama, Shigeyuki; Kuwasako, Kanako

Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture 基因尺度的体外重组实验表明，组蛋白乙酰化直接调控染色质结构。

Science Advances

IF12.5

2025-11-19

PREAI

Yohsuke T. Fukai; Tomoya Kujirai; Masatoshi Wakamori; Setsuko Kanamura; Lisa Yamauchi; Somayeh Zeraati; Satoshi Morita; Chiharu Tanegashima; Mitsutaka Kadota; Mikako Shirouzu; Hitoshi Kurumizaka; Takashi Umehara; Kyogo Kawaguchi

Structural basis for E3 ubiquitin ligase UHRF1 binding to nucleosome core particle and histone H3 ubiquitination E3泛素连接酶UHRF1与核小体核心颗粒结合及组蛋白H3泛素化的结构基础

Journal of Biological Chemistry

IF3.9

2025-11-04

OAAI

Reia Shikimachi; Shun Matsuzawa; Hiroki Onoda; Tsuyoshi Konuma; Atsushi Yamagata; Mikako Shirouzu; Kosuke Yamaguchi; Kyohei Arita

Monoclonal antibodies against human TMPRSS2 prevent infection by any SARS-CoV-2 variant 针对人TMPRSS2的单克隆抗体可阻止任何SARS-CoV-2变种的感染

iScience

IF4.1

2025-08-22

OAAI

Michishige Harada; Takehisa Matsumoto; Mizuki Yamamoto; Jin Goda; Akiko Idei; Kenichi Ohtaki; Natsuki Kojima; Natsumi Yoneda; Kosuke Miyauchi; Kazushige Katsura; Mariko Ikeda; Kazuharu Hanada; Yoshiko Ishizuka-Katsura; Toshiaki Hosaka; Tamao Hisano; Toshie Kaizuka; Takako Yamamoto; Masashi Matsuda; Manabu Nakayama; Akiko Sugimoto-Ishige; Machie Sakuma; Rina Hashimoto; Kazuo Takayama; Misako Nakayama; Cong Thanh Nguyen; Hirohito Ishigaki; Yasushi Itoh; Yoshinobu Hashizume; Minoru Yoshida; Yasushi Kawaguchi; Makoto Takeda; Haruhiko Koseki; Mikako Shirouzu; Jun-ichiro Inoue; Takashi Saito

A new BMP type 1 receptor kinase inhibitor for safe and efficient oral treatment to prevent genetically induced heterotopic ossification in mice 一种新型BMP type 1受体激酶抑制剂，用于安全高效地口服治疗以预防小鼠中遗传性诱导的异位骨化

Bone

IF3.6

2025-06-12

PREAI

Jingwen Yang; Haichun Pan; Katsuhiko Sekimata; Charles Hwang; Anshul Kulkarni; Hannah Thomas; Jade Lindenau; Tyler Duford; Hiroki Ueharu; Akiko Tanaka; Naoki Sakai; Mikako Shirouzu; Yoshinobu Hashizume; Benjamin Levi; Hiroo Koyama; Yuji Mishina

Structural insights into promoter-proximal pausing of RNA polymerase II at+1 nucleosome RNA聚合酶II在+1核小体处的启动子邻近暂停的结构见解

SCIENCE ADVANCES

IF12.5

2025-03-07

OAAI

Naganuma, Masahiro; Kujirai, Tomoya; Ehara, Haruhiko; Uejima, Tamami; Ito, Tomoko; Goto, Mie; Aoki, Mari; Henmi, Masami; Miyamoto-Kohno, Sayako; Shirouzu, Mikako; Kurumizaka, Hitoshi

Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2024-12-01

PREAI

Murayama, Kazutaka; Kato-Murayama, Miyuki; Hosaka, Toshiaki; Kitamura, Toshio; Yokoyama, Shigeyuki; Shirouzu, Mikako

Cyanorhodopsin-II represents a yellow-absorbing proton-pumping rhodopsin clade within cyanobacteria

ISME JOURNAL

IF10

2024-11-01

OAAI

Hasegawa-Takano, Masumi; Hosaka, Toshiaki; Kojima, Keiichi; Nishimura, Yosuke; Kurihara, Marie; Nakajima, Yu; Ishizuka-Katsura, Yoshiko; Kimura-Someya, Tomomi; Shirouzu, Mikako; Sudo, Yuki; Yoshizawa, Susumu

EVA1-antibody drug conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells EVA1-antibody药物偶联物是消除胶质母细胞瘤起始细胞的新治疗策略

NEURO-ONCOLOGY

IF13.4

2024-10-29

PREAI

Hou, Jiahui; Uejima, Tamami; Tanaka, Miho; Son, You Lee; Hanada, Kazuharu; Kukimoto-Niino, Mutsuko; Yamaguchi, Shigeru; Hashimoto, Shigeru; Yokoyama, Shigeyuki; Takemori, Toshitada; Saito, Takashi; Shirouzu, Mikako; Kondo, Toru

A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis 用氨基戊酰胺进行的tRNA修饰有助于蛋白质合成中的AUA解码

NATURE CHEMICAL BIOLOGY

IF13.7

2024-09-19

OAAI

Miyauchi, Kenjyo; Kimura, Satoshi; Akiyama, Naho; Inoue, Kazuki; Ishiguro, Kensuke; Vu, Thien-Son; Srisuknimit, Veerasak; Koyama, Kenta; Hayashi, Gosuke; Soma, Akiko; Nagao, Asuteka; Shirouzu, Mikako; Okamoto, Akimitsu; Waldor, Matthew K.; Suzuki, Tsutomu

E22G Aβ40 fibril structure and kinetics illuminate how Aβ40 rather than Aβ42 triggers familial Alzheimer's

NATURE COMMUNICATIONS

IF15.7

2024-08-15

OAAI

Tehrani, Mohammad Jafar; Matsuda, Isamu; Yamagata, Atsushi; Kodama, Yu; Matsunaga, Tatsuya; Sato, Mayuko; Toyooka, Kiminori; Mcelheny, Dan; Kobayashi, Naohiro; Shirouzu, Mikako; Ishii, Yoshitaka

Structural analyses of the GI.4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies

JOURNAL OF VIROLOGY

IF3.8

2024-05-14

OAAI

Kimura-Someya, Tomomi; Katsura, Kazushige; Kato-Murayama, Miyuki; Hosaka, Toshiaki; Uchikubo-Kamo, Tomomi; Ihara, Kentaro; Hanada, Kazuharu; Sato, Shin; Murayama, Kazutaka; Kataoka, Michiyo; Shirouzu, Mikako; Someya, Yuichi

Structural and dynamic insights into the activation of the μ-opioid receptor by an allosteric modulator

NATURE COMMUNICATIONS

IF15.7

2024-05-13

OAAI

Kaneko, Shun; Imai, Shunsuke; Uchikubo-Kamo, Tomomi; Hisano, Tamao; Asao, Nobuaki; Shirouzu, Mikako; Shimada, Ichio

Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A

NATURE COMMUNICATIONS

IF15.7

2024-04-18

OAAI

Yamagata, Atsushi; Ito, Kaori; Suzuki, Takehiro; Dohmae, Naoshi; Terada, Tohru; Shirouzu, Mikako

Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine 对异亮氨酸trna与赖苷和阿马替丁的解码能力的结构见解

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-03-27

PREAI

Akiyama, Naho; Ishiguro, Kensuke; Yokoyama, Takeshi; Miyauchi, Kenjyo; Nagao, Asuteka; Shirouzu, Mikako; Suzuki, Tsutomu

Molecular basis of ligand recognition specificity of flavone glucosyltransferases in Nemophila menziesii

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2024-03-01

PREAI

Murayama, Kazutaka; Kato-Murayama, Miyuki; Hosaka, Toshiaki; Okitsu, Naoko; Tanaka, Yoshikazu; Shirouzu, Mikako

研究方向