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Distinct outcomes from targeted perturbations of the multi-subunit SCFSkp2 E3 ubiquitin ligase in blocking Trp53/Rb1-null prostate tumorigenesis Xue, Yingjiao; Zhu, Liang; Karan, Saumen; Locker, Joseph D.; Branch, Craig; Zhang, Jinghang; Hoang, Bang; Maianti, Juan Pablo; Zhao, Hongling; Schwartz, Edward L. 分享 收藏
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Hepatocyte-specific fi c Epidermal Growth Factor Receptor Deletion Promotes Fibrosis but has no Effect on Steatosis in Fast-food Diet Model of Metabolic Dysfunction-associated Steatotic Liver Disease Bano, Shehnaz; Copeland, Matthew A.; Stoops, John W.; Orr, Anne; Jain, Siddhi; Paranjpe, Shirish; Mooli, Raja Gopal Reddy; Ramakrishnan, Sadeesh K.; Locker, Joseph; Mars, Wendy M.; Michalopoulos, George K.; Bhushan, Bharat 分享 收藏
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Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease Chen, Tianyi; Dalton, George; Oh, Seh-Hoon; Maeso-Diaz, Raquel; Du, Kuo; Meyers, Rachel A.; Guy, Cynthia; Abdelmalek, Manal F.; Henao, Ricardo; Guarnieri, Paolo; Pullen, Steven S.; Gregory, Simon; Locker, Joseph; Brown, J. Mark; Diehl, Anna Mae 分享 收藏
Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells Long, Kimberly R.; Rbaibi, Youssef; Bondi, Corry D.; Ford, B. Rhodes; Poholek, Amanda C.; Boyd-Shiwarski, Cary R.; Tan, Roderick J.; Locker, Joseph D.; Weisz, Ora A. 分享 收藏
Yes-Associated Protein Is Crucial for Constitutive Androstane Receptor-Driven Hepatocyte Proliferation But Not for Induction of Drug Metabolism Genes in Mice Bhushan, Bharat; Molina, Laura; Koral, Kelly; Stoops, John W.; Mars, Wendy M.; Banerjee, Swati; Orr, Anne; Paranjpe, Shirish; Monga, Satdarshan P.; Locker, Joseph; Michalopoulos, George K. 分享 收藏
Transcriptional Programs Driving Shear Stress-Induced Differentiation of Kidney Proximal Tubule Cells in Culture Park, Hyun Jung; Fan, Zhenjiang; Bai, Yulong; Ren, Qidong; Rbaibi, Youssef; Long, Kimberly R.; Gliozzi, Megan L.; Rittenhouse, Natalie; Locker, Joseph D.; Poholek, Amanda C.; Weisz, Ora A. 分享 收藏
Genetic and pharmacologic inhibition of Skp2, an E3 ubiquitin ligase and RB1-target, has antitumor activity in RB1-deficient human and mouse small cell lung cancer (SCLC) Zhao, Hongling; Sukrithan, Vineeth; Iqbal, Niloy; Nicholas, Cari; Xue, Yingjiao; Locker, Joseph; Zou, Juntao; Zhu, Liang; Schwartz, Edward L. 分享 收藏
Targeted Inhibition of the E3 Ligase SCFSkp2/Cks1 Has Antitumor Activity in RB1-Deficient Human and Mouse Small-Cell Lung Cancer Zhao, Hongling; Iqbal, Niloy J.; Sukrithan, Vineeth; Nicholas, Cari; Xue, Yingjiao; Yu, Cindy; Locker, Joseph; Zou, Juntao; Schwartz, Edward L.; Zhu, Liang 分享 收藏
Pharmacologic Inhibition of Epidermal Growth Factor Receptor Suppresses Nonalcoholic Fatty Liver Disease in a Murine Fast-Food Diet Model Bhushan, Bharat; Banerjee, Swati; Paranjpe, Shirish; Koral, Kelly; Mars, Wendy M.; Stoops, John W.; Orr, Anne; Bowen, William C.; Locker, Joseph; Michalopoulos, George K. 分享 收藏
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Shear stress and oxygen availability drive differential changes in opossum kidney proximal tubule cell metabolism and endocytosis Ren, Qidong; Gliozzi, Megan L.; Rittenhouse, Natalie L.; Edmunds, Lia R.; Rbaibi, Youssef; Locker, Joseph D.; Poholek, Amanda C.; Jurczak, Michael J.; Baty, Catherine J.; Weisz, Ora A. 分享 收藏
Hdac1 Regulates Differentiation of Bipotent Liver Progenitor Cells During Regeneration via Sox9b and Cdk8 Ko, Sungjin; Russell, Jacquelyn O.; Tian, Jianmin; Gao, Ce; Kobayashi, Makoto; Feng, Rilu; Yuan, Xiaodong; Shao, Chen; Ding, Huiguo; Poddar, Minakshi; Singh, Sucha; Locker, Joseph; Weng, Hong-Lei; Monga, Satdarshan P.; Shin, Donghun 分享 收藏
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