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C

Christoph Lange

harvard university

71H指数
334论文数
1.7W被引数
收录论文 90
发表时间
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Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer’s disease兴奋性神经元和抑制性神经元对阿尔茨海默病的分子特征
errMolecular Neurodegeneration
IF17.5
err2025-10-03
err0
errOAAI
errIsabel Castanho; Pourya Naderi Yeganeh; Carles A. Boix; Sarah L. Morgan; Hansruedi Mathys; Dmitry Prokopenko; Bartholomew White; Larisa M. Soto; Giulia Pegoraro; Saloni Shah; Athanasios Ploumakis; Nikolas Kalavros; David A. Bennett; Christoph Lange; Doo Yeon Kim; Lars Bertram; Li-Huei Tsai; Manolis Kellis; Rudolph E. Tanzi; Winston Hide
err分享
err收藏
The Importance of Sensitivity Analyses for the MR Steiger Approach敏感性分析对MR Steiger方法的重要性
errGENETIC EPIDEMIOLOGY
IF3.8
err2025-10-01
err0
errOAAI
errLutz, Sharon M.; Voorhies, Kirsten; Hokanson, John E.; Vansteelandt, Stijn; Lange, Christoph
err分享
err收藏
Factors associated with new onset of depression and anxiety symptoms differ by sex in the COPDGene studyCOPDGene研究中，与抑郁和焦虑症状新发相关的因素因性别而异。
errJournal of Psychosomatic Research
IF3.3
err2025-08-07
err0
PREAI
errKirsten Voorhies; Jess G. Fiedorowicz; Abebaw M. Yohannes; Gregory L. Kinney; Dawn L. DeMeo; Elizabeth A. Regan; James D. Crapo; Edwin K. Silverman; Christoph Lange; Karin F. Hoth; Sharon M. Lutz
err分享
err收藏
A calcium-sensing receptor allelic series and underdiagnosis of genetically driven hypocalcemia钙离子感受器等位基因系列及基因驱动的低钙血症漏诊
erramerican journal of human genetics
IF0
err2025-07-14
err0
errOAAI
errJeremy B. Chang; Connor P. Barnhill; Alexander M. Apostolov; Marcus M. Soliai; Julian Hecker; Jovia L. Nierenberg; Lyndsay M. Stapleton Smith; Arun S. Mathew; Xue Zeng; Jiayin Diao; C. Dilanka Fernando; Qingwen Chen; Ben W. Dulken; Aleksandr Petukhov; Russ Altman; Tracy M. Josephs; Jessica A. Lasky-Su; Caroline M. Gorvin; Mary Scott Roberts; Scott H. Adler; Jonathan C. Fox; Christoph Lange; Sun-Gou Ji
err分享
err收藏
A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s diseasePKCη错义突变增强了高尔基体定位的信号传导，并与隐性遗传性家族性阿尔茨海默病相关。
errScience Signaling
IF6.6
err2025-07-01
err0
PREAI
errMaria Celeste Gauron; Dmitry Prokopenko; Sanghun Lee; Sarah A. Wolfe; Julian Hecker; Julian Willett; Mohammad Waqas; Gema Lordén; Yimin Yang; Joshua E. Mayfield; Isabel Castanho; Kristina Mullin; Sarah Morgan; Georg Hahn; Dawn L. Demeo; Winston Hide; Lars Bertram; Christoph Lange; Alexandra C. Newton; Rudolph E. Tanzi
err分享
err收藏
Associations of APOE variants with sphingomyelin and cholesterol metabolites across the life-course in diverse populationsAPOE变异与鞘磷脂和胆固醇代谢物在生命历程中不同人群中的关联
errMETABOLOMICS
IF3.3
err2025-05-07
err0
PREAI
errLee, Sanghun; Kelly, Rachel S.; Chen, Yulu; Waqas, Mohammad; Mendez, Kevin M.; Hecker, Julian; Hahn, Georg; Lutz, Sharon M.; Celedon, Juan C.; Clish, Clary B.; Litonjua, Augusto A.; Chen, Qingwen; Mcgeachie, Michael; Choi, Younjung; Weiss, Scott T.; Tanzi, Rudolph E.; Lange, Christoph; Prokopenko, Dmitry; Lasky-Su, Jessica A.
err分享
err收藏
On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs代谢物数量性状位点的分析：不同数据转换和研究设计的影响
errSCIENCE ADVANCES
IF12.5
err2025-04-11
err0
errOAAI
errLee, Sanghun; Kelly, Rachel S.; Mendez, Kevin M.; Prokopenko, Dmitry; Hahn, Georg; Lutz, Sharon M.; Celedon, Juan C.; Clish, Clary B.; Weiss, Scott T.; Lange, Christoph; Lasky-Su, Jessica A.
err分享
err收藏
Assessing polyomic risk to predict Alzheimer's disease using a machine learning model使用机器学习模型评估多因素风险以预测阿尔茨海默氏病
errALZHEIMERS & DEMENTIA
IF11.1
err2024-11-07
err0
errOAAI
errNgai, Tiffany; Willett, Julian; Waqas, Mohammad; Fishbein, Lucas H.; Choi, Younjung; Hahn, Georg; Mullin, Kristina; Lange, Christoph; Hecker, Julian; Tanzi, Rudolph E.; Prokopenko, Dmitry
err分享
err收藏
Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2024-06-05
err1
errOAAI
errHahn, Georg; Prokopenko, Dmitry; Hecker, Julian; Lutz, Sharon M.; Mullin, Kristina; Sejour, Leinal; Hide, Winston; Vlachos, Ioannis; DeSantis, Stacia; Tanzi, Rudolph E.; Lange, Christoph
err分享
err收藏
A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables
errPLOS GENETICS
IF3.7
err2022-11-16
err3
errOAAI
errHecker, Julian; Prokopenko, Dmitry; Moll, Matthew; Lee, Sanghun; Kim, Wonji; Qiao, Dandi; Voorhies, Kirsten; Kim, Woori; Vansteelandt, Stijn; Hobbs, Brian D.; Cho, Michael H.; Silverman, Edwin K.; Lutz, Sharon M.; DeMeo, Dawn L.; Weiss, Scott T.; Lange, Christoph
err分享
err收藏
FGF20 and PGM2 variants are associated with childhood asthma in family-based whole-genome sequencing studies
errHUMAN MOLECULAR GENETICS
IF3.2
err2022-10-18
err2
errOAAI
errHecker, Julian; Chun, Sung; Samiei, Ahmad; Liu, Cuining; Laurie, Cecelia; Kachroo, Priyadarshini; Lutz, Sharon M.; Lee, Sanghun; Smith, Albert, V; Lasky-Su, Jessica; Cho, Michael H.; Sharma, Sunita; Quiros, Manuel Enrique Soto; Avila, Lydiana; Celedon, Juan C.; Raby, Benjamin; Zhou, Xiaobo; Silverman, Edwin K.; DeMeo, Dawn L.; Lange, Christoph; Weiss, Scott T.
err分享
err收藏
DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and AdolescentsDDX58与儿童和青少年重症流感病毒感染易感性相关
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2022-08-20
err4
errOAAI
errLee, Sanghun; Zhang, Yu; Newhams, Margaret; Novak, Tanya; Thomas, Paul G.; Mourani, Peter M.; Hall, Mark W.; Loftis, Laura L.; Cvijanovich, Natalie Z.; Tarquinio, Keiko M.; Schwarz, Adam J.; Weiss, Scott L.; Thomas, Neal J.; Markovitz, Barry; Cullimore, Melissa L.; Sanders, Ronald C., Jr.; Zinter, Matt S.; Sullivan, Janice E.; Halasa, Natasha B.; Bembea, Melania M.; Giuliano, John S.; Typpo, Katri, V; Nofziger, Ryan A.; Shein, Steven L.; Kong, Michele; Coates, Bria M.; Weiss, Scott T.; Lange, Christoph; Su, Helen C.; Randolph, Adrienne G.
err分享
err收藏
Zinc finger protein 33B demonstrates sex interaction with atopy-related markers in childhood asthma
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2022-08-11
err1
PREAI
errLee, Sanghun; Prokopenko, Dmitry; Kelly, Rachel S.; Lutz, Sharon; Lasky-Su, Jessica Ann; Cho, Michael H.; Laurie, Cecelia; Celedon, Juan C.; Lange, Christoph; Weiss, Scott T.; Hecker, Julian; DeMeo, Dawn L.
err分享
err收藏
Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data使用全基因组序列数据评估罕见遗传变异对慢性阻塞性肺疾病表型的贡献
errHUMAN MOLECULAR GENETICS
IF3.2
err2022-06-29
err3
errOAAI
errKim, Wonji; Hecker, Julian; Barr, R. Graham; Boerwinkle, Eric; Cade, Brian; Correa, Adolfo; Dupuis, Josee; Gharib, Sina A.; Lange, Leslie; London, Stephanie J.; Morrison, Alanna C.; O'Connor, George T.; Oelsner, Elizabeth; Psaty, Bruce M.; Vasan, Ramachandran S.; Redline, Susan; Rich, Stephen S.; Rotter, Jerome, I; Yu, Bing; Lange, Christoph; Manichaikul, Ani; Zhou, Jin J.; Sofer, Tamar; Silverman, Edwin K.; Qiao, Dandi; Cho, Michael H.
err分享
err收藏
Genome-wide polygenic score to predict chronic kidney disease across ancestries
errNATURE MEDICINE
IF50
err2022-06-16
err62
errOAAI
errKhan, Atlas; Turchin, Michael C.; Patki, Amit; Srinivasasainagendra, Vinodh; Shang, Ning; Nadukuru, Rajiv; Jones, Alana C.; Malolepsza, Edyta; Dikilitas, Ozan; Kullo, Iftikhar J.; Schaid, Daniel J.; Karlson, Elizabeth; Ge, Tian; Meigs, James B.; Smoller, Jordan W.; Lange, Christoph; Crosslin, David R.; Jarvik, Gail P.; Bhatraju, Pavan K.; Hellwege, Jacklyn N.; Chandler, Paulette; Torvik, Laura Rasmussen; Fedotov, Alex; Liu, Cong; Kachulis, Christopher; Lennon, Niall; Abul-Husn, Noura S.; Cho, Judy H.; Ionita-Laza, Iuliana; Gharavi, Ali G.; Chung, Wendy K.; Hripcsak, George; Weng, Chunhua; Nadkarni, Girish; Irvin, Marguerite R.; Tiwari, Hemant K.; Kenny, Eimear E.; Limdi, Nita A.; Kiryluk, Krzysztof
err分享
err收藏
Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C
errNATURE COMMUNICATIONS
IF15.7
err2022-05-27
err34
errOAAI
errTang, Juanjie; Novak, Tanya; Hecker, Julian; Grubbs, Gabrielle; Zahra, Fatema Tuz; Bellusci, Lorenza; Pourhashemi, Sara; Chou, Janet; Moffitt, Kristin; Halasa, Natasha B.; Schwartz, Stephanie P.; Walker, Tracie C.; Tarquinio, Keiko M.; Zinter, Matt S.; Staat, Mary A.; Gertz, Shira J.; Cvijanovich, Natalie Z.; Schuster, Jennifer E.; Loftis, Laura L.; Coates, Bria M.; Mack, Elizabeth H.; Irby, Katherine; Fitzgerald, Julie C.; Rowan, Courtney M.; Kong, Michele; Flori, Heidi R.; Maddux, Aline B.; Shein, Steven L.; Crandall, Hillary; Hume, Janet R.; Hobbs, Charlotte, V; Tremoulet, Adriana H.; Shimizu, Chisato; Burns, Jane C.; Chen, Sabrina R.; Moon, Hye Kyung; Lange, Christoph; Randolph, Adrienne G.; Khurana, Surender
err分享
err收藏
Promoting Sustainability through Next-Generation Biologics Drug Development
errSUSTAINABILITY
IF3.3
err2022-04-07
err2
errOAAI
errPaulick, Katharina; Seidel, Simon; Lange, Christoph; Kemmer, Annina; Cruz-Bournazou, Mariano Nicolas; Baier, Andre; Haehn, Daniel
err分享
err收藏
Reply to Neupane et al.: Replication study of AD-associated rare variants
errALZHEIMERS & DEMENTIA
IF11.1
err2022-02-09
err0
errOAAI
errProkopenko, Dmitry; Morgan, Sarah L.; Lange, Christoph; Hide, Winston; Bertram, Lars; Tanzi, Rudolph E.
err分享
err收藏
Novel recessive locus for body mass index in childhood asthma
errTHORAX
IF7.7
err2021-04-22
err3
errOAAI
errLee, Sanghun; Lasky-Su, Jessica; Won, Sungho; Laurie, Cecelia; Celedon, Juan Carlos; Lange, Christoph; Weiss, Scott; Hecker, Julian
err分享
err收藏
The Role of SNP Interactions when Determining Independence of Novel Signals in Genetic Association Studies-An Application to ARG1 and Bronchodilator Response
errJOURNAL OF PERSONALIZED MEDICINE
IF3
err2021-02-19
err0
errOAAI
errWalsh, Ryan; Voorhies, Kirsten; Mcdonald, Merry-Lynn; McGeachie, Michael; Sordillo, Joanne E.; Lange, Christoph; Wu, Ann Chen; Lutz, Sharon M.
err分享
err收藏

研究方向

暂无研究方向
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