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Alexandra C. Newton

University of California System

77H指数
335论文数
2.5W被引数
收录论文 151
发表时间
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Protein kinase C theta: evolution, regulation, and function蛋白激酶C θ：进化、调控与功能
errBiochemical Journal
IF4.3
err2026-05-01
err0
PREAI
errHodapp, Stefanie J.; Manning, Gerard; Newton, Alexandra C.
err分享
err收藏
C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases蛋白激酶C和Akt的C-spine突变作为一种创建稳定假激酶的新型可推广方法
errJournal of Biological Chemistry
IF3.9
err2025-11-07
err0
errOAAI
errStefanie J. Hodapp; Tiffany H. Kao; Jian Wu; Nileeka Balasuriya; Corina E. Antal; Susan S. Taylor; Alexandra C. Newton
err分享
err收藏
A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s diseasePKCη错义突变增强了高尔基体定位的信号传导，并与隐性遗传性家族性阿尔茨海默病相关。
errScience Signaling
IF6.6
err2025-07-01
err0
PREAI
errMaria Celeste Gauron; Dmitry Prokopenko; Sanghun Lee; Sarah A. Wolfe; Julian Hecker; Julian Willett; Mohammad Waqas; Gema Lordén; Yimin Yang; Joshua E. Mayfield; Isabel Castanho; Kristina Mullin; Sarah Morgan; Georg Hahn; Dawn L. Demeo; Winston Hide; Lars Bertram; Christoph Lange; Alexandra C. Newton; Rudolph E. Tanzi
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err收藏
Sensitive fluorescent biosensor reveals differential subcellular regulation of PKC
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-10-11
err1
PREAI
errSu, Qi; Zhang, Jing; Lin, Wei; Zhang, Jin-Fan; Newton, Alexandra C.; Mehta, Sohum; Yang, Jing; Zhang, Jin
err分享
err收藏
Cancer-associated mutations in protein kinase C theta are loss-of-function
errBIOCHEMICAL JOURNAL
IF4.3
err2024-06-10
err0
errOAAI
errHodapp, Stefanie J.; Gravel, Nathan; Kannan, Natarajan; Newton, Alexandra C.
err分享
err收藏
Exploring Protein Kinase C Theta (PKC.) Signaling In The Generation Of Procoagulant Platelet: Insights From Phosphoproteomics And Systems Analysis
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2024-05-01
err0
PREAI
errZheng, Yiheng; Reitsma, Stephanie; Jordan, Sandler; Babur, Ozgun; Melrose, Alexander; Pang, Jiaqing; Hodapp, Stefanie; Newton, Alexandra; Wilmarth, Phillip; Reddy, Ashok; McCarty, Owen J.; Aslan, Joseph E.
err分享
err收藏
Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput以翻译后修饰为中心的碱基编辑器筛选以评估高通量的磷酸化位点功能
errNATURE METHODS
IF32.1
err2024-04-29
err3
PREAI
errKennedy, Patrick H.; Sheikh, Amin Alborzian Deh; Balakar, Matthew; Jones, Alexander C.; Olive, Meagan E.; Hegde, Mudra; Matias, Maria I.; Pirete, Natan; Burt, Rajan; Levy, Jonathan; Little, Tamia; Hogan, Patrick G.; Liu, David R.; Doench, John G.; Newton, Alexandra C.; Gottschalk, Rachel A.; de Boer, Carl G.; Alarcon, Suzie; Newby, Gregory A.; Myers, Samuel A.
err分享
err收藏
Functional characterisation of a novel mutation in PRKCA, a major driver of chordoid gliomas
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errBellamy, Charlotte; Tovell, Hannah; Dingli, Florent; Loew, Damarys; Liva, Stephane; Schwaighofer, Selina; Stefan, Eduard; Newton, Alexandra; Sanson, Marc; Bielle, Franck
err分享
err收藏
Tatenda Murigo: A passionate advocate for science in Africa (June 17, 2000-July 14, 2023)
errIUBMB LIFE
IF3.2
err2023-09-04
err0
PREAI
errPatten, Victoria; Fischer, Elyse; Penndorf, Patrick; Newton, Alexandra C.
err分享
err收藏
Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation (vol 21, pg 359, 2019)
errNATURE CELL BIOLOGY
IF19.1
err2023-08-14
err0
errOAAI
errJung, Hae-Yun; Fattet, Laurent; Tsai, Jeff H. H.; Kajimoto, Taketoshi; Chang, Qiang; Newton, Alexandra C. C.; Yang, Jing
err分享
err收藏
Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness果糖-1，6-双磷酸酶是一种非酶安全阀，可减少AKT激活以防止胰岛素高反应性
errCELL METABOLISM
IF30.9
err2023-06-01
err8
errOAAI
errGu, Li; Zhu, Yahui; Watari, Kosuke; Lee, Maiya; Liu, Junlai; Perez, Sofia; Thai, Melinda; Mayfield, Joshua E.; Zhang, Bichen; Cunha e Rocha, Karina; Li, Fuming; Kim, Laura C.; Jones, Alexander C.; Wierzbicki, Igor H.; Liu, Xiao; Newton, Alexandra C.; Kisseleva, Tatiana; Lee, Jun Hee; Ying, Wei; Gonzalez, David J.; Saltiel, Alan R.; Simon, M. Celeste; Karin, Michael
err分享
err收藏
Protein Kinase C Theta (PKC.) Signaling Associated With The Generation Of Procoagulant Platelets Revealed By Phosphoproteomics And Systems Analysis
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2023-05-01
err0
PREAI
errZheng, Yiheng; Reitsma, Stephanie; Babur, Ozgun; Melrose, Alexander; Pang, Jiaqing; Hodapp, Stefanie; Newton, Alexandra; Wilmarth, Phillip; Reddy, Ashok; McCarty, Owen J.; Aslan, Joseph E.
err分享
err收藏
Preface to IUBMB life special issue on protein phosphorylation dedicated to Eddy Fischer
errIUBMB LIFE
IF3.2
err2023-03-11
err0
PREAI
errNewton, Alexandra C.; Alessi, Dario R.
err分享
err收藏
The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome SwitchPHLPP1 N端延伸是有丝分裂的Cdk1底物，并控制相互作用的组开关
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err4
errOAAI
errKawashima, Agnieszka T.; Wong, Cassandra; Lorden, Gema; King, Charles C.; Lara-Gonzalez, Pablo; Desai, Arshad; Gingras, Anne-Claude; Newton, Alexandra C.
err分享
err收藏
Protein kinase C showcases allosteric control: activation of LRRK1
errBIOCHEMICAL JOURNAL
IF4.3
err2023-02-10
err2
errOAAI
errTovell, Hannah; Newton, Alexandra C.
err分享
err收藏
The C1A Domain of PKC Confers Sensitivity to Down-Regulation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errKao, Tiffany; Newton, Alexandra
err分享
err收藏
Single Residue Mutation in Protein Kinase C Toggles Between Cancer and Neurodegeneration
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errJones, Alexander; Kornev, Alexandr; Weng, Jody; Manning, Gerard; Taylor, Susan; Newton, Alexandra
err分享
err收藏
Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model
errNATURE COMMUNICATIONS
IF15.7
err2022-11-23
err12
errOAAI
errLorden, Gema; Wozniak, Jacob M.; Dore, Kim; Dozier, Lara E.; Cates-Gatto, Chelsea; Patrick, Gentry N.; Gonzalez, David J.; Roberts, Amanda J.; Tanzi, Rudolph E.; Newton, Alexandra C.
err分享
err收藏
Protein kinase C: release from quarantine by mTORC2蛋白激酶C: mTORC2从检疫中释放
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2022-06-01
err12
errOAAI
errBaffi, Timothy R.; Newton, Alexandra C.
err分享
err收藏
Novel PKC signaling in Alzheimer's Disease
errFASEB JOURNAL
IF4.2
err2022-05-13
err1
PREAI
errGauron, M. C.; Lorden, Gema; Prokopenko, Dmitry; Tanzi, Rudolph; Newton, Alexandra
err分享
err收藏

研究方向

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