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Xinheng He

Chinese Academy of Sciences

37H指数
125论文数
4.2K被引数
收录论文 66
发表时间
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Rational design of a Kappa opioid receptor peptide agonist with attenuated β-arrestin signalingκ阿片受体肽激动剂的理性设计及其β抑制蛋白信号减弱
errNature Communications
IF15.7
err2026-04-14
err0
errOAAI
errHuanhuan Zhang; Ruolan Wang; Pan Shi; Gaoming Wang; Qingjun Zhu; Xinheng He; Youwei Xu; Qingning Yuan; Wen Hu; Kai Wu; Yong Zheng; Li Zhou; Jun Liang; Pei Lv; Ziyan Xu; Fan Yang; Yingbin Liu; Youwen Zhuang; H. Eric Xu; Yue Wang; Changlin Tian
err分享
err收藏
Structure-based design of an opioid receptor modulator for enhanced morphine analgesia基于结构的阿片受体调节剂的设计，以增强吗啡镇痛效果
errScience Advances
IF12.5
err2026-02-11
err0
errOAAI
errYue Wang; Ping Luo; Haiyan Xu; Li Zhan; Kensuke Sakamoto; Mingyu Li; Jing Wang; Xi-Ping Huang; Jianhui Zhou; Tao Liu; Yanrui Suo; Wenjia Fan; Xinheng He; Youwei Xu; Yongjie Cai; Chao Wang; Yuxi Zhao; Antao Dai; Yali Lai; Qingning Yuan; Wen Hu; Kai Wu; Dehua Yang; Xi Cheng; Xiaojie Lu; Brian Krumm; Terry Kenakin; Jian Zhang; Bryan L. Roth; Zhaobing Gao; H. Eric Xu; Youwen Zhuang
err分享
err收藏
Structures of Ostα/β reveal a unique fold and bile acid transport mechanismOstα/β 的结构揭示了独特的折叠和胆汁酸转运机制
errNature
IF48.5
err2026-01-28
err0
PREAI
errXuemei Yang; Nana Cui; Tianyu Li; Xinheng He; Heng Zhang; Canrong Wu; Yang Li; Xiong Ma; H. Eric Xu
err分享
err收藏
An update for AlphaFold3 versus experimental structures: assessing the precision of small molecule binding in GPCRsAlphaFold3与实验结构的更新: 评估gpcr中小分子结合的精确度
errActa Pharmacologica Sinica
IF8.4
err2025-07-09
err0
PREAI
errShi-yi Shen; Jun-rui Li; Yu-song Wang; Shao-ning Li; H. Eric Xu; Xin-heng He
err分享
err收藏
Molecular mechanism of pH sensing and activation in GPR4 reveals proton-mediated GPCR signalingGPR4中pH感应和激活的分子机制揭示了质子介导的GPCR信号
errCell Discovery
IF12.5
err2025-06-25
err0
errOAAI
errChongzhao You; Shimeng Guo; Tianwei Zhang; Xinheng He; Tianyu Gao; Wenwen Xin; Zining Zhu; Yujie Lu; Youwei Xu; Zhen Li; Yumu Zhang; Xi Cheng; Yi Jiang; Xin Xie; H. Eric Xu
err分享
err收藏
Advances in structure-based allosteric drug design
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2025-02-01
err0
PREAI
errLi, Rui; He, Xinheng; Wu, Chengwei; Li, Mingyu; Zhang, Jian
err分享
err收藏
GlycanInsight: an open platform for carbohydrate-binding pocket prediction and characterizationGlycanInsight：一个用于碳水化合物结合口袋预测与表征的开放平台
errCHEMICAL SCIENCE
IF7.4
err2025-01-01
err0
errOAAI
errChu, Qinyu; He, Xinheng; Tan, Xinyi; Gu, Zhiyong; Luo, Yin; Huang, Zifu; Zheng, Mingyue; Cheng, Xi
err分享
err收藏
Molecular basis of lipid and ligand regulation of prostaglandin receptor DP2前列腺素受体DP2的脂质和配体调节的分子基础
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-12-12
err0
errOAAI
errXu, Jiuyin; Xu, Youwei; Hou, Li; He, Xinheng; Li, Yang; Zhao, Jing; Meng, Xue; Wang, James Jiqi; Wu, Yanli; Zhang, Heng; Li, Yunhai; Hu, Wen; Yuan, Qingning; Wu, Kai; Cheng, Xi; Jiang, Yi; Xia, Yu; Xu, H. Eric; Wu, Canrong
err分享
err收藏
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors
errACTA PHARMACOLOGICA SINICA
IF8.4
err2024-12-06
err0
PREAI
errHe, Xin-heng; Li, Jun-rui; Shen, Shi-yi; Xu, H. Eric
err分享
err收藏
Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3生长抑素受体SSTR1和SSTR3的选择性配体识别和激活
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-10-03
err0
errOAAI
errWang, Yujue; Xu, Youwei; Wang, Yue; Zhang, Jie; Chen, Lan; He, Xinheng; Fan, Wenjia; Wu, Kai; Hu, Wen; Cheng, Xi; Yang, Guizhu; Xu, H. Eric; Zhuang, Youwen; Sun, Shuyang
err分享
err收藏
AI-driven antibody design with generative diffusion models: current insights and future directions具有生成扩散模型的AI驱动抗体设计: 当前见解和未来方向
errACTA PHARMACOLOGICA SINICA
IF8.4
err2024-09-30
err1
PREAI
errHe, Xin-heng; Li, Jun-rui; Xu, James; Shan, Hong; Shen, Shi-yi; Gao, Si-han; Xu, H. Eric
err分享
err收藏
Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor催乳素释放肽通过其g蛋白偶联受体识别和信号传导的分子机制
errCELL DISCOVERY
IF12.5
err2024-09-03
err0
errOAAI
errLi, Yang; Yuan, Qingning; He, Xinheng; Zhang, Yumu; You, Chongzhao; Wu, Canrong; Li, Jingru; Xu, H. Eric; Zhao, Li-Hua
err分享
err收藏
Structural insights into ligand recognition, selectivity, and activation of bombesin receptor subtype-3对蛙皮素受体subtype-3的配体识别，选择性和激活的结构见解
errCELL REPORTS
IF6.9
err2024-08-01
err0
errOAAI
errLi, Changyao; Xu, Youwei; Su, Wenxin; He, Xinheng; Li, Jingru; Li, Xinzhu; Xu, H. Eric; Yin, Wanchao
err分享
err收藏
Structural and functional evidence that GPR30 is not a direct estrogen receptor (Vol 34, Pg 530, 2024)
errCELL RESEARCH
IF25.9
err2024-07-29
err0
errOAAI
errLiu, Heng; Guo, Shimeng; Dai, Antao; Xu, Peiyu; Li, Xin; Huang, Sijie; He, Xinheng; Wu, Kai; Zhang, Xinyue; Yang, Dehua; Xie, Xin; Xu, H. Eric
err分享
err收藏
Structural basis for hormone recognition and distinctive Gq protein coupling by the kisspeptin receptor
errCELL REPORTS
IF6.9
err2024-07-01
err2
errOAAI
errShen, Shiyi; Wang, Dongxue; Liu, Heng; He, Xinheng; Cao, Yinglong; Chen, Juanhua; Li, Shujie; Cheng, Xi; Xu, H. Eric; Duan, Jia
err分享
err收藏
Molecular basis for the activation of PAF receptor by PAF
errCELL REPORTS
IF6.9
err2024-07-01
err1
PREAI
errFan, Wenjia; Xu, Youwei; He, Xinheng; Luo, Ping; Zhu, Jingpeng; Li, Junrui; Wang, Ruolan; Yuan, Qingning; Wu, Kai; Hu, Wen; Zhao, Yuxi; Xu, Shiqi; Cheng, Xi; Wang, Yue; Xu, H. Eric; Zhuang, Youwen
err分享
err收藏
Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2
errACTA PHARMACEUTICA SINICA B
IF14.6
err2024-07-01
err1
errOAAI
errZheng, Miao; Feng, Bo; Zhang, Yumin; Liu, Xin; Zhao, Na; Liu, Hui; Xu, Zichao; He, Xinheng; Qu, Zhiyan; Chen, Shizhao; Jiang, Zhidong; Cheng, Xi; Liu, Hong; Zang, Yi; Zhao, Lin- xiang; Zheng, Jie; Zhang, Leike; Li, Jia; Zhou, Yu
err分享
err收藏
Highly accurate carbohydrate-binding site prediction with DeepGlycanSite使用DeepGlycanSite进行高度准确的碳水化合物结合位点预测
errNATURE COMMUNICATIONS
IF15.7
err2024-06-17
err4
errOAAI
errHe, Xinheng; Zhao, Lifen; Tian, Yinping; Li, Rui; Chu, Qinyu; Gu, Zhiyong; Zheng, Mingyue; Wang, Yusong; Li, Shaoning; Jiang, Hualiang; Jiang, Yi; Wen, Liuqing; Wang, Dingyan; Cheng, Xi
err分享
err收藏
Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor
errCELL DISCOVERY
IF12.5
err2024-06-04
err0
errOAAI
errJin, Sanshan; Guo, Shimeng; Xu, Youwei; Li, Xin; Wu, Canrong; He, Xinheng; Pan, Benxun; Xin, Wenwen; Zhang, Heng; Hu, Wen; Yin, Yuling; Zhang, Tianwei; Wu, Kai; Yuan, Qingning; Xu, H. Eric; Xie, Xin; Jiang, Yi
err分享
err收藏
Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1人琥珀酸受体sukr1的配体识别和激活的分子基础
errCELL RESEARCH
IF25.9
err2024-06-04
err1
PREAI
errLi, Changyao; Liu, Heng; Li, Jingru; He, Xinheng; Zhu, Haoran; Fu, Wei; Xu, H. Eric
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
B
Bryan L. Roth
H 指数: 139 · 论文数: 971
蒋
蒋华良 (Hualiang Jiang)
H 指数: 101 · 论文数: 983
H
H. Eric Xu
H 指数: 100 · 论文数: 624
张建 封面图
张建 (Jian Zhang)
H 指数: 99 · 论文数: 1.6K
邓
邓海腾 (Haiteng Deng)
H 指数: 81 · 论文数: 470
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