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N

Niek N. Sanders

Ghent University
H指数:58
被引数:1.2万

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Engineered adipose-derived stem cells with self-amplifying RNA enhance vascular network formation in porous GelMA hydrogels

工程化脂肪来源干细胞与自扩增RNA增强多孔GelMA水凝胶中的血管网络形成

Biomaterials Science
IF5.7
2026-01-010
PRE
Florian Vanlauwe; Thaïs De Witte; Gerben Michiels; Viktor Eeckhout; Arjen Dewaele; Amber Demeulenaere; Ode Mattheeuws; Sabina Shamieva; E. Aslan; Laura Schelfaut; Pieter Vervaeke; Thomas Naert; Sandra Van Vlierberghe; Niek N. Sanders; Phillip Nicholas Blondeel
Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye

LNP介导的mRNA和自扩增RNA经玻璃体内注射在 MOUSE EYE 中的有效性对比免疫原性

Journal of Controlled Release
IF11.5
2025-07-120
PRE
Weiran Li; Helena Vanluchene; Laura Raes; Karen Peynshaert; Lien Veys; Sofía González Hernández; Emily De Lombaerde; Bruno G. De Geest; Niek N. Sanders; Lieve Moons; Koen Raemdonck; Lies De Groef; Katrien Remaut
Mucosal administration of lipid nanoparticles containing self-amplifying mRNA induces local uptake and expression in a pig model as a potential vaccination platform against STIs

脂质纳米颗粒含自扩增mRNA的黏膜给药在猪模型中诱导局部摄取和表达，作为一种针对STIs的潜在疫苗接种平台

Drug Delivery and Translational Research
IF5.5
2025-06-110
OAAI
Ibe Van de Casteele; Magalie Plovyt; Magdalena Stuchlíková; Michiel Lanssens; Ben Verschueren; Quenten Denon; Paul Van der Meeren; Sean McCafferty; Arlieke Gitsels; Pieter Cornillie; Niek N. Sanders; Aster Vandierendonck; Katrien C. K. Poelaert; Daisy Vanrompay
A Fentanyl Hapten-Displaying Lipid Nanoparticle Vaccine that Non-Covalently Encapsulates a TLR7/8 Agonist and T-Helper Epitope Induces Protective Anti-Fentanyl Immunity
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2024-11-211
PRE
Zhong, Zifu; Deventer, Marie H.; Chen, Yong; Vanhee, Stijn; Lammens, Ines; Deswarte, Kim; Huang, Yi; Ye, Tingting; Wang, Haixiu; Nuhn, Lutz; Vandeputte, Marthe M.; Gontsarik, Mark; Cui, Xiaole; Sanders, Niek N.; Lienenklaus, Stefan; Lambrecht, Bart N.; Baptista, Antonio P.; Stove, Christophe P.; G. De Geest, Bruno
Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β-Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activation

通过在含有 β-氨基酯可电离脂质的脂质纳米颗粒中递送的自我扩增mRNA来扩增蛋白质表达与降低的先天免疫激活相关

ACS NANO
IF16
2024-10-010
PRE
De Lombaerde, Emily; Cui, Xiaole; Chen, Yong; Zhong, Zifu; Deckers, Julie; Mencarelli, Giulia; Opsomer, Lisa; Wang, Haixiu; De Baere, Jamie; Lienenklaus, Stefan; Lambrecht, Bart N.; Sanders, Niek N.; De Geest, Bruno G.
Chitin-mediated blockade of chitinase-like proteins reduces tumor immunosuppression, inhibits lymphatic metastasis and enhances anti-PD-1 efficacy in complementary TNBC models

几丁质介导的几丁质酶样蛋白阻断可减少肿瘤免疫抑制，抑制淋巴转移并增强互补TNBC模型中的anti-PD-1功效

BREAST CANCER RESEARCH
IF5.6
2024-04-111
OAAI
Salembier, Robbe; De Haes, Caro; Bellemans, Julie; Demeyere, Kristel; van den Broeck, Wim; Sanders, Niek N.; Van Laere, Steven; Lyons, Traci R.; Meyer, Evelyne; Steenbrugge, Jonas
Combinatorial Screening of Biscarbamate Ionizable Lipids Identifies a Low Reactogenicity Lipid for Lipid Nanoparticle mRNA Delivery

双氨基甲酸酯可电离脂质的组合筛选确定了用于脂质纳米颗粒mRNA递送的低反应原性脂质

ADVANCED FUNCTIONAL MATERIALS
IF19
2024-02-016
OA
De Lombaerde, Emily; Chen, Yong; Ye, Tingting; Deckers, Julie; Mencarelli, Giulia; De Swarte, Kim; Lauwers, Heleen; De Coen, Ruben; Kasmi, Sabah; Bevers, Sanne; Kuchmiy, Anna; Bogaert, Bram; Baekens, Lies; Zhong, Zifu; Lamoot, Alexander; Sanders, Niek N.; Lambrecht, Bart N.; Baptista, Antonio P.; De Koker, Stefaan; De Geest, Bruno G.

研究方向

暂未获取到该数据
J
Joseph Demeester
H 指数:44论文数:139被引数:7,631
Z
Zifu Zhong
H 指数:20论文数:60被引数:1,548
S
Stefaan C. De Smedt
H 指数:106论文数:616被引数:3.9万
B
Bruno G. De Geest
H 指数:65论文数:313被引数:1.5万
S
Stefan Lienenklaus
H 指数:49论文数:167被引数:8,480
R
Roosmarijn E. Vandenbroucke
H 指数:60论文数:229被引数:1.4万
D
De Smedt, Stefaan C.
H 指数:0论文数:197被引数:53
B
Bart N. Lambrecht
H 指数:123论文数:763被引数:6.3万
F
Francis Combes
H 指数:15论文数:30被引数:823
I
Ine Lentacker
H 指数:41论文数:145被引数:6,762