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M

Maria-Clemencia Hernandez

roche innovation center basel
H指数:22
被引数:2,572

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RO4938581, a GABAA-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndrome

RO4938581，一种GABAA-α5负性别构调节剂，拯救了Dup15q综合征小鼠模型的表型和EEG表型。

Molecular Psychiatry
IF10.1
2026-01-050
OAAI
Ryoko Nakagawa; Francesca Nani; Joerg F. Hipp; Michael Honer; Frederic Knoflach; Rodolfo Gasser; Laurence Ozmen; Kota Tamada; Fatiha Fjeldskaar; Livia Takacs; Audrey Vautheny; Stephen R. Morairty; Michael Saxe; Toru Takumi; Maria-Clemencia Hernandez
A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a GABAA-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome
JOURNAL OF NEURODEVELOPMENTAL DISORDERS
IF4
2022-02-0519
OAAI
Goeldner, Celia; Kishnani, Priya S.; Skotko, Brian G.; Casero, Julian Lirio; Hipp, Joerg F.; Derks, Michael; Hernandez, Maria-Clemencia; Khwaja, Omar; Lennon-Chrimes, Sian; Noeldeke, Jana; Pellicer, Sabine; Squassante, Lisa; Visootsak, Jeannie; Wandel, Christoph; Fontoura, Paulo; D'Ardhuy, Xavier Liogier
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man
SCIENTIFIC REPORTS
IF3.9
2021-04-0823
OAAI
Hipp, Joerg F.; Knoflach, Frederic; Comley, Robert; Ballard, Theresa M.; Honer, Michael; Trube, Gerhard; Gasser, Rodolfo; Prinssen, Eric; Wallace, Tanya L.; Rothfuss, Andreas; Knust, Henner; Lennon-Chrimes, Sian; Derks, Michael; Bentley, Darren; Squassante, Lisa; Nave, Stephane; Noldeke, Jana; Wandel, Christoph; Thomas, Andrew W.; Hernandez, Maria-Clemencia

研究方向

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F
Frédéric Knoflach
H 指数:34论文数:77被引数:4,993
J
Joerg F. Hipp
H 指数:36论文数:117被引数:6,648
M
Mark A. Israel
H 指数:65论文数:562被引数:1.6万
D
Daniel Bertrand
H 指数:85论文数:464被引数:2.6万
L
Lisa Squassante
H 指数:25论文数:101被引数:2,544
O
Omar Khwaja
H 指数:34论文数:143被引数:6,211
S
Sian Lennon-Chrimes
H 指数:4论文数:16被引数:117
C
Christoph Wandel
H 指数:19论文数:88被引数:2,356
T
Theresa M. Ballard
H 指数:27论文数:76被引数:3,119
M
Michael Honer
H 指数:41论文数:230被引数:6,004