冯娟 (Juan Feng)

Peking University专职副研究员

H指数:39

被引数:4,798

个人简介

"冯娟，副教授，硕士生导师，深圳市“鹏程孔雀计划”特聘岗位人才（C）\n邮箱：fengjuan@sztu.edu.cn\n2013年本科毕业于山东大学，2019年获得清华大学生物学博士学位，2019年7月加入深圳技术大学。主要研究方向包括：基于人工智能/多组学的疾病标志物/靶点/药物发现；代谢性疾病/炎性衰老诊疗。已发表SCI论文30多篇，其中以第一作者或通讯作者发表SCI论文15篇（其中包括中科院1区TOP期刊5篇，JCR Q1期刊10篇）。担任多个中科院一区期刊审稿人，申请专利7项（授权2项），参编中英文专著各1部。主持国家自然科学基金青年项目、深圳市优秀科技创新人才培养计划、深圳市自然科学基础研究面上项目、省级重点实验室开放课题以及校级项目2项。本科期间获国家奖学金、一等奖学金等多项荣誉，博士期间获清华大学研究生综合优秀一等奖学金。在深圳技术大学任职期间获“润园优秀教师”“校优秀班主任”“校讲课竞赛三等奖”，指导研究生获得国家级学术论坛奖项1项，指导本科生参与互联网+项目获奖10余项，“优秀毕业论文”1项，多名学生升学国内985/211高校或入职行业头部企业。\n主持或参与的基金项目\n1.国家自然科学基金青年科学基金项目，2023-01-01至2025-12-31，30万元，在研，结题。\n2.深圳市基础研究专项（自然科学基金）基础研究面上项目，2024-11-27至2027-11-26，30万元，在研，主持\n3.深圳市优秀科技创新人才培养计划，2022-04-01至2024-04-01，30万元，在研，结题\n4.广东省新药筛选重点实验室开放基金，2021-07-01至2022-07-01，2.5万元，结题，主持\n5.深圳市科技创新委员会面上项目，2020-01-01至2022-12-31，40万元，在研，主要参与人。\n6.广东省教育厅抗新型冠状病毒专项，2020-04-01至2021-09-30，30万元，结题，参与。\n专著\n1.《精准健康管理》，陈大方著，北京大学医学出版社，2021，ISBN：9787565922381（参编第四章《多组学》）\n代表文章\n1.Feng J#, Zuo L#, Li WX, Wang XW, Hong JM, Qixin Weng QX, Chenghao Lv CH, Saeede MS, Qin S*, Li LR*, Zheng YF*. Hawk tea extract inhibits hepatic de novo lipogenesis and lipid accumulation in MAFLD via the ROCK1-PPP1CB-AMPK pathway. Food & Medicine Homology, 2026,In presss\n2.Wang XW#, Hong JM#,Liang R#, Bao SQ, Li LR*, Wang J*,Feng J*. Obacunone ameliorates high-fat diet-induced MAFLD by regulating the PPARγ-FABP1/CD36 axis and the gut-liver crosstalk. Phytomedicine, 2025, 147:157180.\n3.Wang J, Li XC, Li CH, Bao SQ, Liu LJ, Wang ZJ,Feng J*. The Codonopsis pilosula water extract improves testicular inflammatory aging in D-galactose-induced aging mice by modulating the CLEC7A/inflammasome pathway. Journal of Ethnopharmacology, 2025, 346:119645.\n4.Wang J, Bao SQ, Li CH, An Q,Feng J*. Roles of extracellular vesicles from different origins in metabolic-associated fatty liver disease: Progress and perspectives. Frontiers in Immunology, 2025, 1544012.\n3.Feng J, Dang HL, Zhang XL, Huang WT, Ma CM; Zhang AX, Hao MM，Xie L, Auniversal gene expression signature-based strategy for the high-throughput discovery of anti-inflammatory drugs. Inflammation Research, 2025, 74(1).\n5.Zhang LL,Zheng Y, Shao MY; Chen AP, Liu MY, Sun WL, Li TX, Fang YN, Dong Y, Zhao SP, Luo H,Feng J* Wang Q*, Li LR*, Zheng YF*. AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease. Pharmacological Research, 2025, 212: 107617.\n6.Wang XW, Kang JC, Li XC, Wu PM, Yong Huang Y, Duan YQ,Feng J*, Wang J*. Codonopsis pilosula water extract delays D-galactose-induced aging of the brain in mice by activating autophagy and regulating metabolism. Journal of Ethnopharmacology, 2024, 327: 118016.\n7.Feng，J., Wang, Y.F., Li, W.X., Zhao,Y., Liu，Y., Yao, X.G., Liu, S.W., Yu, P., Li, R.S. High levels of oxidized fatty acids in HDL impair the antioxidant function of HDL in patients with diabetes. Frontiers in Endocrinology 2022, 993193.\n8.Feng, J., Ge, C.C., Li, W.X., Li, R.S. 3-(3-Hydroxyphenyl) propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression. Fitoterapia 2022, 156:105071.\n9.Ge, C.C.#,Feng, J.#, Zhang, J.M., Hu, K., Wang, D., Zha, L., Hu, X.J., Li, R.S. Aptamer/antibody sandwich method for digital detection of SARS-CoV2 nucleocapsid Protein. Talanta, 2021, 236:122847\n10.Feng, J., Cavallero, S., Hsiai, T., Li, R.S. Impact of air pollution on intestinal redox lipidome and microbiome. Free Radic Biol Med, 2020, 151:99-110.\n11.Feng, J., Yang, J., Chang, Y.J, Qiao L.S., Dang, H.L., Luo, K., Guo H.Y., An, Y.N., Ma, C.M., Shao, H., Tian, J., Yuan, Y., Xie, L., Xing, W.L., Cheng, J. Caffeine-free hawk tea lowers cholesterol by reducing free cholesterol uptake and the production of very low-density lipoprotein. Commun Biol, 2019, 2:173.\n招聘信息\n欢迎各类专业背景（生物学、生物信息学、医学、生医工程、化学、药学等）的本科生报考硕士研究生，欢迎本科生和硕士生加入本课题组学习，实习和交换。"