Xian Wang - Publications, H-index & Citations

王献 (Xian Wang)

Hainan Medical University

64H指数

486论文数

1.6W被引数

收录论文 176

发表时间

Interaction Mechanisms of KRAS G12C Inhibitors (Sotorasib and Adagrasib) with Human Serum Albumin: Insights from Spectroscopic and Molecular Docking Studies KRAS G12C 抑制剂（Sotorasib 和 Adagrasib）与人血清白蛋白的相互作用机制：来自光谱学和分子对接研究的见解

Molecules

IF4.6

2026-03-03

OAAI

Junsong Qin; Zhepeng Chen; Chuangyan Wang; Lin Mai; Xian Wang; Junfeng Li; Hui Liu; Yun Song

Novel CDK2/4/6 inhibitor culmerciclib (TQB3616) plus fulvestrant in previously treated, HR-positive, HER2-negative advanced breast cancer: a randomized, double-blind, phase 3 trial 新型CDK2/4/6抑制剂culmerciclib (TQB3616) 联合氟维司群治疗HR阳性HER2-negative晚期乳腺癌: 一项随机、双盲、3期临床试验

Signal Transduction and Targeted Therapy

IF52.7

2025-12-18

OAAI

Yongmei Yin; Qingyuan Zhang; Tao Sun; Chunfang Hao; Zhihong Wang; Jin Yang; Yongsheng Wang; Yanxia Shi; Jing Sun; Quchang Ouyang; Haichuan Su; Jinsheng Wu; Lu Gan; Meng Han; Liming Gao; Xiaojia Wang; Bing Zhao; Hui Li; Jiuda Zhao; Hongwei Yang; Fangling Ning; Fuguo Tian; Juliang Zhang; Hongmei Sun; Zhaofeng Niu; Hong Zong; Aimin Zang; Xinshuai Wang; Xinyu Qian; Shikai Wu; Jianyun Nie; Lijia He; Ying Cheng; Yanrong Hao; Yi Zhai; Huiping Li; Jingfen Wang; Shihong Wei; Man Li; Yunjiang Liu; Hongqiang Guo; Qun Hu; Lina Liu; Xinghua Han; Ruizhen Luo; Mingli Ni; Xianjun Tang; Zhenhua Zhai; Meiqian Ding; Haibo Wang; Peng Shen; Xian Wang; Lian Liu; Wenyan Chen; Gang Liu; Zhengwen Cai; Zefei Jiang

Multi-Omics Decoding of Dendrobium huoshanense's Dual-Target Mechanism: Modulating Purine and Ether Lipid Metabolism for Type 2 Diabetes Therapy 多组学解析霍山石斛的双靶点机制：调节嘌呤和醚脂质代谢以治疗2型糖尿病

eFood

IF5.7

2025-12-08

OAAI

Jun Dai; Zhibo Wang; Xian Wang; Sifan Guo; Yan Wang; Ying Cai; Dandan Xie; Yujuan Wang; Aihua Zhang; Shi Qiu; Shaojiang Zheng

Sacituzumab Tirumotecan in Participants With Advanced or Metastatic Urothelial Carcinoma and Disease Progression after Chemotherapy and Immune Checkpoint Inhibitors 萨卡图zumab替拉他滨在具有进展期或转移性尿路上皮癌且在化疗和免疫检查点抑制剂治疗后疾病进展的受试者中的应用

Annals of Oncology

IF65.4

2025-11-21

PREAI

Y. Zhu; S. Jiang; Y. Shi; S. Wang; F. Yuan; F. Zhou; K. Jiang; X. Zhang; L. Seneviratne; G. Yu; M. Zhang; T. Liu; X. Li; X. Chen; X. Wang; S. Zhang; Y. Liu; Y. Ge; M. Chen; G. Blumenthal

Exploration of hanging coffin customs and the bo people in China through comparative genomics 通过比较基因组学研究中国悬棺习俗和博人群体

Nature Communications

IF15.7

2025-11-20

OAAI

Hui Zhou; Le Tao; Yinhui Zhao; Haifeng He; Hong Shi; Tengsong Yu; Yaozheng Guo; Yaoxi He; Hong Liu; Yun Wu; Jiayong Cao; Zhenyu Kuang; Shifeng Wu; Fuchun Lin; Yundong Yang; Lifeng Xiong; Yilan Liu; Kongyang Zhu; Yu Xu; Shengmin Huang; Xiaomin Yang; Rui Wang; Baitong Wang; Xian Wang; Wen-Jing Lu; Wibhu Kutanan; Rasmi Shoocongdej; Bing Su; Chuan-Chao Wang; Xueping Ji; Xiaoming Zhang

The metformin mediated MAPK signaling pathway influences D-Xylose regulation during diabetic kidney disease therapy 二甲双胍介导的MAPK信号通路影响糖尿病肾病治疗期间D-木糖的调控

Communications Medicine

IF6.3

2025-11-04

OAAI

Dandan Xie; Yongjun Zhu; Sifan Guo; Hao Li; Zhibo Wang; Xian Wang; Ying Cai; Jinxuan Chai; Yan Wang; Zhencai Hu; Shiwei Wang; Lasi Chen; Shi Qiu; Yiqiang Xie; Aihua Zhang

Spatial Metabolomics Identifies Riboflavin Metabolism as a Therapeutic Target of Huangqi Guizhi Wuwu Decoction in Diabetic Nephropathy

BIOMEDICAL CHROMATOGRAPHY

IF1.7

2025-11-01

PREAI

Qiu, Shi; Wang, Zhibo; Wang, Xian; Guo, Sifan; Cai, Ying; Xie, Dandan; Hu, Zhencai; Wang, Shiwei; Yang, Qiang; Zhang, Aihua

Beamion BCGC-1: phase Ib/II trial of zongertinib for advanced HER2-positive breast or gastroesophageal cancers Beamion BCGC-1：zongertinib治疗晚期HER2阳性乳腺癌或胃肠癌的Ib/II期临床试验

Future Oncology

IF2.6

2025-10-17

OAAI

Sara Hurvitz; Matteo Simonelli; Ramón Yarza; David Berz; Shigehisa Kitano; Gianluca Del Conte; Daniel Acosta Eyzaguirre; Bernard Gaston Doger de Speville Uribe; Daniela Maier; Damijan Erzen; Sila Aykut Yazgili; Giuseppe Curigliano; Ting Deng; Min Yan; Qingyuan Zhang; Xian Wang; Izuma Nakayama; Kohei Shitara

Inhibition of LARP4-mediated quiescence exit of naive CD4+ T cells ameliorates autoimmune and allergic diseases 抑制幼稚CD4 T细胞的LARP4-mediated静止退出可改善自身免疫和过敏性疾病

Nature Biomedical Engineering

IF26.6

2025-10-16

PREAI

Jian Zhou; Di Yang; Chao Han; Hui Dong; Shufeng Wang; Xiang Li; Jun Hu; Cui Wang; Jie Luo; Zhiyuan Wei; Taiping Liu; Shuai Xu; Chen Xu; Yiwei Zhang; Xian Wang; Yuanyu Deng; Baiqing Li; Ruihan Mao; Mingyang Zhang; Yi Sun; Xinyuan Zhou; Lilin Ye; Bing Ni; Jun Zhu; Juan Li; Jingbo Zhang; Tingting Zhao; Xiangmei Chen; Rong Lin; Yi Zhang; Yuzhang Wu; Yi Tian

Satellite data-driven estimation of daily and 500 m net ecosystem exchange over China during 2003–2020 基于卫星数据的2003—2020年中国区域日尺度与500米净生态系统交换量估算

Remote Sensing of Environment

IF11.4

2025-09-30

PREAI

Xian Wang; Yongqiang Zhang; Xuanze Zhang; Shaoyang He; Dongdong Kong; Jing Tian; Haoshan Wei; Longhao Wang; Yu Quan; Yufeng Zheng; Yingping Wang

Identification of a new CD46 gene mutation site in a family with atypical hemolytic uremic syndrome 在一个具有非典型溶血尿毒综合征的家族中发现一个新的CD46基因突变位点

BMC NEPHROLOGY

IF2.4

2025-09-22

OAAI

Hu, Benjin; Wang, Xu; Wang, Xian; Zhang, Hongchuan; Mei, Dongdong; Guo, Xiaohua; Li, Xiaowei

Tumor-associated neutrophils promote breast cancer progression via RLN2/RXFP1-C6orf99-STAT3 axis 肿瘤相关中性粒细胞通过RLN2/RXFP1-C6orf99-STAT3轴促进乳腺癌进展

International Immunopharmacology

IF4.7

2025-09-08

PREAI

Shujing Wang; Youjing Sheng; Wuqin Xu; Xian Wang; Leon Müller; Zhengsheng Wu; Zhenzhong Feng; Qiang Wu

Fluid shear stress activates a targetable mechano-metastatic cascade to promote medulloblastoma metastasis 流体剪切应力激活了一个可靶向的机械性转移级联，以促进髓母细胞瘤转移。

Nature Biomedical Engineering

IF26.6

2025-09-02

PREAI

Hyun-Kee Min; Hongyu Zhao; Alexander Bahcheli; Peng Pan; Jade Chan; Junsheng Chen; Esther Low; Yuxiao Zhou; Xian Wang; Savo Bajic; Ran Peng; Siyi Wanggou; Qi Yang; Robert Du Yang Zhang; Leiming Wang; Xiufang Ren; Haoyue Qi; Yu Shi; Madeline N. Hayes; Brian Ciruna; Jüri Reimand; Xinyu Liu; Xi Huang

Metabolite-Guided Acetylation Therapy: Astragaloside IV Reverses Diabetic Nephropathy via Gna13-Driven Purine Metabolic Reprogramming 代谢物引导的乙酰化疗法：Astragaloside IV通过Gna13驱动的嘌呤代谢重编程逆转糖尿病肾病

Food Frontiers

IF6.9

2025-08-28

OAAI

Shi Qiu; Sifan Guo; Dandan Xie; Zhibo Wang; Ying Cai; Xian Wang; Qiang Yang; Chunsheng Lin; Hong Yao; Qiqi Zhao; Yu Guan; Songqi Tang; Yiqiang Xie; Aihua Zhang

Integrated Omics Reveal Dendrobium nobile Lindl.’s Anti-Diabetic Mechanisms via Arginine-Proline and Glycerophospholipid Pathways 整合组学揭示铁皮石斛通过精氨酸-脯氨酸和甘油磷脂通路发挥抗糖尿病机制

pharmaceuticals

IF0

2025-07-28

OAAI

Zhibo Wang; Xian Wang; Sifan Guo; Dandan Xie; Yujuan Wang; Jun Dai; Shi Qiu

Comprehensive multiomics revealed astragaloside IV regulating carbohydrate metabolism dysfunction through clinical, animal and cellular platforms 综合多组学分析揭示了黄芪甲苷IV通过临床、动物和细胞平台调节碳水化合物代谢功能障碍。

FOOD BIOSCIENCE

IF5.9

2025-06-01

PREAI

Qiu, Shi; Guo, Sifan; Xie, Dandan; Wang, Zhibo; Cai, Ying; Wang, Xian; Lin, Chunsheng; Yao, Hong

Raddeanin A exerts potent efficacy against non-small cell lung cancer by inhibiting cyclin-dependent kinase 6 Raddeanin A通过抑制cyclin-dependent kinase 6对非小细胞肺癌发挥显著疗效。

TRANSLATIONAL ONCOLOGY

IF4.1

2025-06-01

PREAI

Wang, Xian; Lin, Xiao; Liu, Yuxin; Ma, Chunbo; Liu, Mengchu; Bai, Jiayu; Ye, Yihan; Zhao, Chengguang; Yang, Lehe; Huang, Xiaoying; Wang, Liangxing

Housing and husbandry factors affecting zebrafish novel tank test responses: a global multi-laboratory study 影响斑马鱼新水箱测试反应的饲养和繁育因素：一项全球多实验室研究

LAB ANIMAL

IF3.9

2025-05-26

OAAI

Hillman, Courtney; Fontana, Barbara D.; Amstislavskaya, Tamara G.; Gorbunova, Maria A.; Altenhofen, Stefani; Barthelson, Karissa; Bastos, Leonardo M.; Borba, Joao V.; Bonan, Carla D.; Brennan, Caroline H.; Farias-Cea, Amaury; Cooper, Austin; Corcoran, Jamie; Dondossola, Eduardo R.; Martinez-Duran, Luis M.; Gallas-Lopes, Matheus; Galstyan, David S.; Garcia, Ella O.; Gerken, Ewan; Hindges, Robert; Kenney, Justin W.; Kleshchev, Maxim A.; Kolesnikova, Tatiana O.; Leggieri, Adele; Khatsko, Sergey L.; Lardelli, Michael; Lodetti, Guilherme; Lombardelli, Giulia; Luchiari, Ana C.; Portela, Stefani M.; Medan, Violeta; Moutinho, Lirane M.; Nekhoroshev, Evgeny V.; Petersen, Barbara D.; Petrunich-Rutherford, Maureen L.; Piato, Angelo; Porfiri, Maurizio; Read, Emily; Resmim, Cassio M.; Rico, Eduardo P.; Rosemberg, Denis B.; de Abreu, Murilo S.; Salazar, Catia A.; Stahlhofer-Buss, Thailana; Teixeira, Julia R.; Valentim, Ana M.; Zhdanov, Alexander V.; Iturriaga-Vasquez, Patricio; Wang, Xian; Wong, Ryan Y.; Parker, Matthew O.

Research on the three-body kelp harvesting ship based on floating raft aquaculture mode 基于浮动筏式养殖模式的三体式海带收割船研究

AQUACULTURAL ENGINEERING

IF4.3

2025-05-20

PREAI

Wang, Xian; Wang, Yanan; Li, Zhengzhong; Che, Hailong; Zhu, Lanlan; Sheng, Tongfei; Zhou, Hua; Geng, Duanyang

Capivasertib plus fulvestrant in patients with HR-positive/HER2-negative advanced breast cancer: phase 3 CAPItello-291 study extended Chinese cohort Capivasertib 联合 Fulvestrant 治疗HR阳性/HER2阴性晚期乳腺癌：CAPItello-291研究扩展的中国队列

NATURE COMMUNICATIONS

IF15.7

2025-05-09

OAAI

Hu, Xichun; Zhang, Qingyuan; Sun, Tao; Xiong, Huihua; Li, Wei; Teng, Yuee; Lu, Yen-Shen; Tseng, Ling-Ming; Yan, Min; Li, Hongsheng; Pang, Danmei; -Chen, Shin-Cheh; Chen, Wenyan; Jiang, Ou; Wang, Jingfen; Wu, Xinhong; Wang, Xian; Zang, Aimin; Wang, Xiaojia; Collins, Julie M.; Fan, Ethan; Jiang, Lin; Zeng, Xiaoling; Turner, Nicholas C.

研究方向