Moorthy P. Ponnusamy - Publications, H-index & Citations

Moorthy P. Ponnusamy

University of Nebraska Medical Center

52H指数

263论文数

7.7K被引数

收录论文 120

发表时间

Abexinostat attenuates temozolomide-resistant glioma stem cells Abexinostat减轻替莫唑胺耐药性胶质瘤干细胞

Neuro-Oncology

IF13.4

2026-08-19

PREAI

Balaji Perumalsamy; Raghupathy Vengoji; Anand Thiraviyam; Indumati Ramireddy; Poonam Yadav; Ashu Shah; Kavita Mallya; Afshin Salehi; Sushil Kumar; Maneesh Jain; Moorthy P Ponnusamy; Surinder K Batra; Nicole Shonka

Distinct glycosyltransferase expression governs organ-specific survival in pancreatic cancer metastasis 特异性的糖基转移酶表达调控胰腺癌转移的器官特异性存活

Oncogene

IF7.3

2026-07-30

OAAI

Venkatesh Varadharaj; Frank Leon; Nivedeta Krishna Kumar; Palanisamy Nallasamy; Pratima Raut; Annant Bir Kaur; Kirtana Arikath; Wyatt Petersen; Sanchita Rauth; Neelanjana Gayen; Zahraa Wajih Alsafwani; Poompozhil Mathivanan; Saravanakumar Marimuthu; Kavita Mallya; Madhu Bommideni; Jesse L. Cox; Geoffrey A. Talmon; Paul M. Grandgenett; Michael A. Hollingsworth; Dominick J. DiMaio; Jean L. Grem; Surinder K. Batra; Moorthy P. Ponnusamy

Rab5 Nucleotide Binding Promotes Oxidative Metabolism to Fuel Hepatocellular Carcinoma Cell Proliferation Rab5核苷酸结合促进氧化代谢，为肝细胞癌细胞增殖提供能量

Journal of Biological Chemistry

IF3.9

2026-02-25

OAAI

Kelly O. Otakhor; Mohd Ali Abbas Zaidi; Rebecca Oberley-Deegan; Moorthy P. Ponnusamy; Kurt W. Fisher; Micah B. Schott

Targeting the DDX3/PAF1 Axis Enhances Chemotherapy Efficacy in Pancreatic Ductal Adenocarcinoma

Cancer Letters

IF10.1

2026-01-23

PREAI

Palanisamy Nallasamy; Parthasarathy Seshacharyulu; Sanchita Rauth; Ashu Shah; Saravanakumar Marimuthu; Venkatesh Varadharaj; Madhulatha Bommideni; Kavita Mallya; Zahraa Wajih Alsafwani; Subodh M. Lele; Venu Raman; Surinder K. Batra; Moorthy P. Ponnusamy

A Timeless Chronicle: Effects of Cigarette Smoke on GPR15 Receptor and Its Oncogenic Potential 永恒的编年史：香烟烟雾对GPR15受体及其致癌潜力的影响

Cancer Letters

IF10.1

2025-12-16

PREAI

Poompozhil Mathivanan; Pratima Raut; Neelanjana Gayen; Apar K. Ganti; Moorthy P. Ponnusamy; Surinder K. Batra

RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer RASH3D19通过正反馈回路介导KRAS突变癌症中的RAS激活

Nature Cell Biology

IF19.1

2025-12-01

PREAI

Warapen Treekitkarnmongkol; Hiroshi Katayama; Deivendran Sankaran; Mei-Chee Tai; Sanchita Rauth; Hanxiao Chen; Tristian Nguyen; Kieko Hara; Fredrik I. Thege; Moorthy P. Ponnusamy; Surinder K. Batra; Huamin Wang; Ignacio I. Wistuba; Thomas D. Schmittgen; John V. Heymach; Scott Kopetz; Tony Hu; Wantong Yao; Anirban Maitra; Subrata Sen

Unveiling the gut-pancreas axis: microbial influence on stemness and tumor microenvironment of PDAC

Stem Cells

IF3.6

2025-09-27

OAAI

Kirtana Arikath; Surinder K Batra; Moorthy P Ponnusamy

Targeting cancer-associated fibroblast-driven LIF/LIFR axis improves the therapeutic efficacy of gemcitabine and nab-paclitaxel in pancreatic cancer 靶向癌症相关成纤维细胞驱动的LIF/LIFR轴可提高吉西他滨和nab-紫杉醇在胰腺癌中的治疗效果

npj Precision Oncology

IF8

2025-08-22

OAAI

Rakesh Bhatia; Imran Khan; Xiaoqi Li; Shailendra Gautam; Parthasarathy Seshacharyulu; Zahraa Wajih Alsafwani; Namita Bhyravbhatla; Moorthy P. Ponnusamy; Maneesh Jain; Mokenge Malafa; Santhamma Bindu; Ahmed Gulzar; Hareesh Nair; Surinder K. Batra; Sushil Kumar

Emerging pathways yielding opportunities for future treatments in pancreatic ductal adenocarcinoma 新兴通路为胰腺导管腺癌的未来治疗带来机遇

Expert Opinion on Therapeutic Targets

IF4.4

2025-05-22

PREAI

Ashu Shah; Esther Johnson; Moorthy P. Ponnusamy; Surinder K. Batra

ProteotoxomiRs: Diagnostic and pathologic miRNA signatures for reductive stress induced proteotoxic heart disease 蛋白质组学：还原应激诱导的蛋白质毒性心脏病中用于诊断和病理学的miRNA特征

REDOX BIOLOGY

IF11.9

2025-04-01

OAAI

Karthikeyan, Santhosh Kumar; Nallasamy, Palanisamy; Cleveland, Jarrell Matthew; Arulmani, Ahila; Raveendran, Ashvanthi; Karimi, Mariam; Ansari, Mohammad Owais; Challa, Anil Kumar; Ponnusamy, Moorthy P.; Benjamin, Ivor J.; Rajasekaran, Namakkal S.

Contract to kill: GNAS mutation 合同杀人：GNAS突变

MOLECULAR CANCER

IF33.9

2025-03-07

OAAI

Raut, Pratima; Mathivanan, Poompozhil; Batra, Surinder K.; Ponnusamy, Moorthy P.

PAF1-mediated transcriptional reprogramming confers docetaxel resistance in advanced prostate cancer

CANCER LETTERS

IF10.1

2025-01-01

PREAI

Muniyan, Sakthivel; Vengoji, Raghupathy; Nimmakayala, Rama Krishna; Seshacharyulu, Parthasarathy; Perumalsamy, Balaji; Alsafwani, Zahraa Wajih; Kakar, Sham S.; Smith, Lynette M.; Shonka, Nicole; Teply, Benjamin A.; Lele, Subodh M.; Ponnusamy, Moorthy P.; Batra, Surinder K.

THE ROLE OF HOXC10 IN DRIVING GLIOBLASTOMA AGGRESSIVENESS

NEURO-ONCOLOGY

IF13.4

2024-11-11

PREAI

Vengoji, Raghupathy; Perumalsamy, Balaji; Thiraviyam, Anand; Ogunleye, Ayoola; Jain, Maneesh; Ponnusamy, Moorthy; Batra, Surinder; Shonka, Nicole

Unveiling the resistance to therapies in pancreatic ductal adenocarcinoma

DRUG RESISTANCE UPDATES

IF21.7

2024-11-01

PREAI

Shah, Ashu; Ganguly, Koelina; Rauth, Sanchita; Sheree, Shamema S.; Khan, Imran; Ganti, Apar K.; Ponnusamy, Moorthy P.; Kumar, Sushil; Jain, Maneesh; Batra, Surinder K.

Emerging Trends in Gastrointestinal Cancer Targeted Therapies: Harnessing Tumor Microenvironment, Immune Factors, and Metabolomics Insights 胃肠癌靶向治疗的新趋势: 利用肿瘤微环境，免疫因素和代谢组学见解

GASTROENTEROLOGY

IF25.1

2024-10-01

PREAI

Rauth, Sanchita; Malafa, Mokenge; Ponnusamy, Moorthy P.; Batra, Surinder K.

PAF1/HIF1α axis rewires the glycolytic metabolism to fuel aggressiveness of pancreatic cancer PAF1/HIF1α 轴重新连接糖酵解代谢以促进胰腺癌的侵袭性

CANCER & METABOLISM

IF5.3

2024-09-06

OAAI

Ogunleye, Ayoola O.; Gayen, Neelanjana; Rauth, Sanchita; Marimuthu, Saravanakumar; Nimmakayala, Rama Krishna; Alsafwani, Zahraa W.; Cox, Jesse L.; Batra, Surinder K.; Ponnusamy, Moorthy P.

Secretory Trefoil Factor 1 (TFF1) promotes gemcitabine resistance through chemokine receptor CXCR4 in Pancreatic Ductal Adenocarcinoma

CANCER LETTERS

IF10.1

2024-08-01

PREAI

Shah, Ashu; Jahan, Rahat; Kisling, Sophia G.; Atri, Pranita; Natarajan, Gopalakrishnan; Nallasamy, Palanisamy; Cox, Jesse L.; Macha, Muzafar A.; Sheikh, Ishfaq Ahmad; Ponnusamy, Moorthy P.; Kumar, Sushil; Batra, Surinder K.

Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis 癌症相关成纤维细胞通过LAMA5/ITGA4轴诱导腺泡-导管细胞转分化和胰腺癌的发生

GASTROENTEROLOGY

IF25.1

2024-05-01

PREAI

Parte, Seema; Kaur, Annant B.; Nimmakayala, Rama Krishna; Ogunleye, Ayoola O.; Chirravuri, Ramakanth; Vengoji, Raghupathy; Leon, Frank; Nallasamy, Palanisamy; Rauth, Sanchita; Alsafwani, Zahraa Wajih; Lele, Subodh; Cox, Jesse L.; Bhat, Ishfaq; Singh, Shailender; Batra, Surinder K.; Ponnusamy, Moorthy P.

PAF1 reprograms metabolism in pancreatic cancer by interacting with HIF1 α

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Ogunleye, Ayoola O.; Gayen, Neelanjana; Marimuthu, Saravanakumar; Nimmakayala, Rama Krishna; Rauth, Sanchita; Alsafwani, Zahraa; Cox, Jesse L.; Batra, Surinder K.; Ponnusamy, Moorthy P.

Connectivity mapping-based identification of pharmacological inhibitor targeting HDAC6 in aggressive pancreatic ductal adenocarcinoma

NPJ PRECISION ONCOLOGY

IF8

2024-03-07

OAAI

Atri, Pranita; Shah, Ashu; Natarajan, Gopalakrishnan; Rachagani, Satyanarayana; Rauth, Sanchita; Ganguly, Koelina; Carmicheal, Joseph; Ghersi, Dario; Cox, Jesse L.; Smith, Lynette M.; Jain, Maneesh; Kumar, Sushil; Ponnusamy, Moorthy P.; Seshacharyulu, Parthasarathy; Batra, Surinder K.

研究方向