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S

Shi‐Yong Sun

Emory University and Winship Cancer Institute

64H指数
532论文数
2.2W被引数
收录论文 167
发表时间
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Targeting MKK3/c-Myc interaction to overcome osimertinib acquired resistance in EGFR mutant lung cancer靶向MKK3/c-Myc相互作用以克服EGFR突变型肺癌中的奥希替尼获得性耐药
errCancer Letters
IF10.1
err2025-08-29
err0
PREAI
errZhen Chen; Karin A. Vallega; Dongsheng Wang; Elsa Bildtsen; Haian Fu; Suresh S. Ramalingam; Andrey A. Ivanov; Shi-Yong Sun
err分享
err收藏
Targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition to delay emergence of acquired resistance of lung cancer to osimertinib通过抑制Mcl-1靶向激活内源性凋亡通路，以延缓肺癌对奥希替尼获得性耐药的出现
errCancer Letters
IF10.1
err2025-07-30
err0
PREAI
errGuangzhi Ma; Dongsheng Wang; Yunfu Deng; Weijia Huang; Yifan Zhai; Shi-Yong Sun
err分享
err收藏
Amino acid transporters mediate autonomous delivery of nanoparticle vehicles into living plants氨基酸转运蛋白介导纳米颗粒载体自主进入活体植物
errNature Communications
IF15.7
err2025-07-21
err0
errOAAI
errXue Xia; Jiawei Dong; Aijie Li; Yanlin Wang; Yang Liu; Yingfang Zhu; Liang Xu; Zhiyang Jing; Jing Wang; Yan Zou; Shiyong Sun; Lu Wang; Yiqing Lu; Alex Soeriyadi; Xuelu Wang; John W. Patrick; Christina E. Offler; Meng Zheng; Chun-Peng Song; Bingyang Shi
err分享
err收藏
Is tumor microenvironment important for targeted therapy in lung cancer?
errCANCER LETTERS
IF10.1
err2024-11-01
err0
PREAI
errSun, Shi-Yong
err分享
err收藏
Spatially resolved subcellular protein-protein interactomics in drug-perturbed lung-cancer cultures and tissues
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-10-30
err0
PREAI
errCai, Shuangyi; Hu, Thomas; Venkataraman, Abhijeet; Moctezuma, Felix G. Rivera; Ozturk, Efe; Zhang, Nicholas; Wang, Mingshuang; Zvidzai, Tatenda; Das, Sandip; Pillai, Adithya; Schneider, Frank; Ramalingam, Suresh S.; Oh, You-Take; Sun, Shi-Yong; Coskun, Ahmet F.
err分享
err收藏
Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E (vol 12, pg 848, 2010)
errNEOPLASIA
IF7.7
err2024-10-01
err0
errOAAI
errLi, Yikun; Yue, Ping; Deng, Xingming; Ueda, Takeshi; Fukunaga, Rikiro; Khuri, Fadlo R.; Sun, Shi-Yong
err分享
err收藏
Inhibition of hTERT/telomerase/telomere mediates therapeutic efficacy of osimertinib in EGFR mutant lung cancer抑制hTERT/端粒酶/端粒介导奥希替尼治疗EGFR突变型肺癌的疗效
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2024-09-19
err1
errOAAI
errChen, Zhen; Vallega, Karin A.; Wang, Dongsheng; Quan, Zihan; Fan, Songqing; Wang, Qiming; Leal, Ticiana; Ramalingam, Suresh S.; Sun, Shi-Yong
err分享
err收藏
SHP2 ablation mitigates osteoarthritic cartilage degeneration by promoting chondrocyte anabolism through SOX9SHP2消融通过SOX9促进软骨细胞合成代谢减轻骨关节炎软骨退变
errFASEB JOURNAL
IF4.2
err2024-09-03
err0
errOAAI
errWang, Lijun; Yang, Huiliang; Wang, Changwei; Wang, Mingliang; Huang, Jiahui; Nyunt, Thedoe; Osorio, Camilo; Sun, Shi-Yong; Pacifici, Maurizio; Lefebvre, Veronique; Moore, Douglas C.; Wang, Shaomeng; Yang, Wentian
err分享
err收藏
Targeting Transient Receptor Potential Melastatin-2 (TRPM2) Enhances Therapeutic Efficacy of Third Generation EGFR Inhibitors against EGFR Mutant Lung Cancer靶向瞬时受体电位Melastatin-2 (TRPM2) 增强第三代EGFR抑制剂对EGFR突变型肺癌的治疗效果
errADVANCED SCIENCE
IF14.1
err2024-07-23
err3
errOAAI
errChen, Zhen; Vallega, Karin A.; Boda, Vijay K.; Quan, Zihan; Wang, Dongsheng; Fan, Songqing; Wang, Qiming; Ramalingam, Suresh S.; Li, Wei; Sun, Shi-Yong
err分享
err收藏
Targeting DNA topoisomerase II to manage acquired resistance to third generation EGFR tyrosine kinase inhibitors in the treatment of EGFR mutant NSCLC
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errChen, Zhen; Vallega, Karin A.; Wang, Dongsheng; Quan, Zihan; Fan, Songqing; Wang, Qiming; Leal, Ticiana A.; Ramalingam, Suresh S.; Sun, Shi-Yong
err分享
err收藏
DNA topoisomerase II inhibition potentiates osimertinib's therapeutic efficacy in EGFR-mutant non-small cell lung cancer modelsDNA拓扑异构酶II抑制增强奥希替尼在EGFR突变非小细胞肺癌模型中的治疗效果
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-03-07
err2
errOAAI
errChen, Zhen; Vallega, Karin A.; Wang, Dongsheng; Quan, Zihan; Fan, Songqing; Wang, Qiming; Leal, Ticiana; Ramalingam, Suresh S.; Sun, Shi-Yong
err分享
err收藏
ALK inhibitors downregulate the expression of death receptor 4 in ALK-mutant lung cancer cells via facilitating Fra-1 and c-Jun degradation and subsequent AP-1 suppression
errNEOPLASIA
IF7.7
err2023-08-01
err1
errOAAI
errZhao, Wen; Yu, Danlei; Zhai, Yifan; Sun, Shi-Yong
err分享
err收藏
ALK inhibitors downregulate the expression of death receptor 4 in ALK-mutant NSCLC cells via facilitating Fra-1 and c-Jun degradation and subsequent AP-1 suppression
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errZhao, Wen; Yu, Danlei; Zhai, Yifan; Sun, Shi-Yong
err分享
err收藏
Darolutamide reverses osimertinib resistance in non-small cell lung cancer
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errSchmitz, John C.; Zhang, Guojing; Liu, Zhentao; Huang, Yufei; Sica, Gabriel; Sun, Shi-Yong; Owonikoko, Taofeek K.
err分享
err收藏
mTOR Complex 2 Stabilizes Mcl-1 Protein by Suppressing Its Glycogen Synthase Kinase 3-Dependent and SCF-FBXW7-Mediated Degradation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err53
errOAAI
errKoo, Junghui; Yue, Ping; Deng, Xingming; Khuri, Fadlo R.; Sun, Shi-Yong
err分享
err收藏
Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors靶向凋亡以管理对第三代EGFR抑制剂的获得性耐药
errFRONTIERS OF MEDICINE
IF3.5
err2022-09-24
err4
PREAI
errSun, Shi-Yong
err分享
err收藏
Therapeutic potential of the novel Bcl-2/Bcl-XL dual inhibitor, APG1252, alone or in combination against non-small cell lung cancer
errMOLECULAR CARCINOGENESIS
IF3.2
err2022-09-06
err3
PREAI
errQian, Luxi; Vallega, Karin A.; Yao, Weilong; Wang, Dongsheng; Zhai, Yifan; He, Xia; Sun, Shi-Yong
err分享
err收藏
Editorial: Challenges and opportunities of TKIs in the treatment of NSCLC patients with uncommon mutations
errFRONTIERS IN ONCOLOGY
IF3.3
err2022-07-26
err0
errOAAI
errSu, Chunxia; Sun, Shi-Yong
err分享
err收藏
Mcl-1 levels critically impact the sensitivities of human colorectal cancer cells to APG-1252-M1, a novel Bcl-2/Bcl-XL dual inhibitor that induces Bax-dependent apoptosis
errNEOPLASIA
IF7.7
err2022-07-01
err10
errOAAI
errYao, Weilong; Bai, Longchuan; Wang, Shaomeng; Zhai, Yifan; Sun, Shi-Yong
err分享
err收藏
Therapeutic efficacy of the novel SHP2 degrader SHP2-D26, alone or in combination, against lung cancer is associated with modulation of p70S6K/S6, Bim and Mcl-1 (Apr, 117, 2022)
errCANCER GENE THERAPY
IF5
err2022-05-10
err0
errOAAI
errDeng, Yunfu; Ma, Guangzhi; Vallega, Karin A.; Wang, Dongsheng; Wang, Mingliang; Wang, Changwei; Wang, Shaomeng; Ramalingam, Suresh S.; Sun, Shi-Yong
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Michael B. Sporn
H 指数: 151 · 论文数: 785
张
张军 (Jun Zhang)
H 指数: 124 · 论文数: 4.5K
S
Suresh S. Ramalingam
H 指数: 124 · 论文数: 1.2K
F
Fadlo R. Khuri
H 指数: 122 · 论文数: 1.1K
D
David H. Gutmann
H 指数: 118 · 论文数: 972
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